1.Easy
Why is HIV treated with a combination of antiretroviral drugs?
- ABecause each single drug cures only part of the infection
- BBecause one drug alone causes no side effects
- CTo make the treatment shorter, usually a few weeks
- DTo suppress the virus and prevent drug resistance
2.Easy
Which drug can be used in beta blocker overdose because it raises heart rate through a non-adrenergic pathway?
- AFlumazenil
- BGlucagon
- CInsulin
- DNaloxone
3.Easy
Why do nurses wear chemotherapy-tested gloves and gowns when handling cytotoxic drugs?
- ATo avoid exposure to drugs that may cause cancer or birth defects
- BBecause cytotoxic drugs are radioactive and give off radiation
- CTo protect the drug from light
- DTo keep the drugs warm during the infusion
4.Medium
Benzathine benzylpenicillin (penicillin G benzathine) is ordered. Which route is correct?
- AIntravenous infusion over 30 minutes
- BDeep intramuscular only
- CSubcutaneous in the abdomen
- DIntravenous push
5.Medium
Which statement about allopurinol is correct?
- AIt increases uric acid production to flush out crystals
- BIt lowers uric acid over time and does not relieve the pain of an acute attack
- CIt is taken only during an acute attack and stopped as soon as the pain settles
- DIt works within an hour to relieve joint pain
6.Medium
Why should doxycycline not be taken at the same time as milk or antacids?
- AThe combination causes severe constipation
- BAntacids turn it into a toxic compound
- CMilk speeds up its breakdown in the liver by inducing enzymes
- DCalcium and other metal ions bind it and reduce absorption
7.Hard
During an IV glyceryl trinitrate (nitroglycerin) infusion for chest pain, the patient's blood pressure drops to 82/50 mmHg and he feels faint. What is the nurse's first action?
- AStop or reduce the infusion as per protocol, lay the patient flat and notify the prescriber
- BSit the patient fully upright and give paracetamol for the headache
- CGive a sublingual nitroglycerin tablet and increase the rate to relieve the remaining chest pain
- DIncrease the infusion rate to improve blood flow to the heart
8.Hard
Zero-order elimination, as seen with alcohol at normal intake, means that:
- AA constant amount is eliminated per unit of time
- BElimination stops at high concentrations
- CA constant fraction is eliminated per unit of time
- DThe half-life stays constant whatever the level
Answer key
- 1. D · To suppress the virus and prevent drug resistance
- 2. B · Glucagon
- 3. A · To avoid exposure to drugs that may cause cancer or birth defects
- 4. B · Deep intramuscular only
- 5. B · It lowers uric acid over time and does not relieve the pain of an acute attack
- 6. D · Calcium and other metal ions bind it and reduce absorption
- 7. A · Stop or reduce the infusion as per protocol, lay the patient flat and notify the prescriber
- 8. A · A constant amount is eliminated per unit of time
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