1.Easy
Which drug reverses the effect of heparin?
- AProtamine sulfate
- BVitamin K
- CFlumazenil
- DNaloxone
2.Easy
Montelukast, used in asthma, belongs to which drug class?
- AAntimuscarinic bronchodilators
- BInhaled corticosteroids
- CLeukotriene receptor antagonists
- DShort-acting beta-2 agonists
3.Easy
Why is methadone used to treat opioid use disorder?
- AIt cures the liver damage caused by opioids
- BIt is a pure opioid antagonist that blocks all opioid effects
- CIt causes vomiting if other opioids are used
- DIt is a long-acting opioid that prevents withdrawal and craving
4.Medium
A 19-year-old starts an SSRI for depression. Which is most important for the nurse to monitor during the first weeks?
- ABlood glucose before every meal and at bedtime
- BHearing loss and tinnitus
- CNew or worsening suicidal thoughts or agitation
- DDaily bowel movements only
5.Medium
A patient takes isoniazid. Which advice is most important?
- AStop the drug when the cough improves
- BExpect the urine to turn orange
- CAvoid alcohol and report jaundice, dark urine or poor appetite
- DTake it with antacids to protect the stomach from irritation
6.Medium
Why should loperamide usually be avoided in bloody diarrhoea with fever?
- ALoperamide makes the bleeding worse by blocking platelets
- BSlowing the gut may keep bacteria and toxins in the bowel longer
- CLoperamide causes severe hypertension when there is an infection
- DLoperamide is an antibiotic that causes resistance
7.Hard
Newborns given chloramphenicol can develop "grey baby syndrome". What is the main reason?
- AImmature glucuronidation in the liver lets the drug accumulate
- BThe newborn kidney excretes the drug too quickly, so higher doses are given
- CChloramphenicol is converted to vitamin K in neonates
- DNewborns produce antibodies against the drug
8.Hard
A drug has a half-life of 6 hours. Its plasma level is 80 mg/L. Assuming first-order elimination and no further doses, what is the level after 18 hours?
- A20 mg/L
- B10 mg/L
- C26.7 mg/L
- D40 mg/L
Answer key
- 1. A · Protamine sulfate
- 2. C · Leukotriene receptor antagonists
- 3. D · It is a long-acting opioid that prevents withdrawal and craving
- 4. C · New or worsening suicidal thoughts or agitation
- 5. C · Avoid alcohol and report jaundice, dark urine or poor appetite
- 6. B · Slowing the gut may keep bacteria and toxins in the bowel longer
- 7. A · Immature glucuronidation in the liver lets the drug accumulate
- 8. B · 10 mg/L
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