1.Easy
How does tamsulosin improve urine flow in benign prostatic hyperplasia?
- AIt increases urine production in the kidney
- BIt contracts the bladder muscle
- CIt blocks alpha-1 receptors and relaxes prostate smooth muscle
- DIt shrinks the prostate gland over months by blocking testosterone
2.Easy
Which of these is an extrapyramidal side effect of antipsychotics?
- AAkathisia (a feeling of inner restlessness)
- BWeight gain
- CAgranulocytosis (a very low neutrophil count)
- DDry mouth
3.Easy
Why is low-dose aspirin given to some people with heart disease?
- ATo relieve chest pain immediately
- BTo lower blood cholesterol levels and stabilise plaques
- CTo slow the heart rate
- DTo reduce platelet aggregation and prevent clots
4.Medium
After instilling eye drops, why should the patient press gently on the inner corner of the eye for a minute or two?
- ATo stop the eye from producing tears for about an hour
- BTo make the pupil dilate faster
- CTo spread the drop evenly over the eyelid
- DTo reduce drainage into the nose and absorption into blood
5.Medium
How does metformin mainly lower blood glucose?
- AIt reduces glucose production by the liver
- BIt blocks glucose absorption in the kidney
- CIt stimulates insulin release from the pancreas
- DIt replaces missing insulin
6.Medium
Why are many drugs started at lower doses in older adults?
- AOlder adults absorb no drugs from the stomach
- BOlder adults always weigh more than younger adults, so drugs last longer
- CKidney and liver clearance often decline, and sensitivity to drugs increases
- DLower doses are cheaper for older patients
7.Hard
Probenecid has been used to raise plasma penicillin levels. How does it do this?
- AIt inhibits the liver metabolism of penicillin
- BIt blocks the tubular secretion of penicillin in the kidney
- CIt displaces penicillin from plasma proteins
- DIt increases the absorption of penicillin from the small intestine
8.Hard
A patient has an anaphylactic reaction to the first dose of amoxicillin. How is this adverse reaction classified in the common A/B system?
- AType B, because it occurs only after long-term use
- BType A, because it is dose-related and predictable from the drug's pharmacology
- CType B, because it is unpredictable and unrelated to the drug's normal action
- DType A, because the dose was too high
Answer key
- 1. C · It blocks alpha-1 receptors and relaxes prostate smooth muscle
- 2. A · Akathisia (a feeling of inner restlessness)
- 3. D · To reduce platelet aggregation and prevent clots
- 4. D · To reduce drainage into the nose and absorption into blood
- 5. A · It reduces glucose production by the liver
- 6. C · Kidney and liver clearance often decline, and sensitivity to drugs increases
- 7. B · It blocks the tubular secretion of penicillin in the kidney
- 8. C · Type B, because it is unpredictable and unrelated to the drug's normal action
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