Pharmacology worksheet with answers

In Addison's disease, fludrocortisone is given to replace which hormone?

1. AThyroxine
2. BAdrenaline
3. CAldosterone
4. DCortisol

Which organ is mainly responsible for metabolising most drugs?

1. ASpleen
2. BLiver
3. CKidney
4. DLung

Dobutamine is mainly used to:

1. ASlow the heart rate in fast atrial fibrillation with low blood pressure
2. BTreat high blood pressure at home
3. CDissolve clots in the coronary arteries
4. DIncrease heart contractility in cardiogenic shock or acute heart failure

Why do NSAIDs such as ibuprofen increase the risk of stomach ulcers?

1. AThey raise the pH of gastric acid
2. BThey increase the number of Helicobacter pylori bacteria in the stomach
3. CThey directly dissolve the mucus layer
4. DThey reduce protective prostaglandins in the stomach lining

A parent will give a liquid medicine to a child at home. Which advice is safest?

1. AUse any kitchen teaspoon
2. BUse the oral syringe or measuring cup supplied with it
3. CEstimate the dose by pouring the liquid into a small cup
4. DMix the dose into a full bottle of milk

During an amphotericin B infusion, the patient has fever, chills and shaking. What is the most likely explanation?

1. ASevere hypoglycaemia caused by the drug
2. BA sign that the drug has been given into an artery
3. CA sign that the fungal infection is cured
4. DA common infusion reaction to amphotericin B

A woman using the combined oral contraceptive pill starts carbamazepine for epilepsy. What is the main concern?

1. ANo concern, because the drugs do not interact
2. BCarbamazepine toxicity because the pill strongly blocks its metabolism
3. CContraceptive failure because the hormones are metabolised faster
4. DSevere hypoglycaemia from the combination

A patient on valproate becomes lethargic, starts vomiting and develops jaundice. Which adverse effect should be suspected first?

1. ALiver toxicity
2. BKidney stones
3. CHypothyroidism
4. DNormal start-up side effects