内外科护理:心血管与呼吸
方法
- 说出问题所在:泵衰竭、动脉阻塞、节律、血栓、气道狭窄、感染或设备问题。
- 先检查危险征象:低氧、低血压、胸痛、新出现的意识模糊、冰冷无脉搏的肢体。
- 让氧疗与患者相匹配:大多数人为 94–98%,有 CO₂ 潴留风险者为 88–92%。
- 把每种药物与其检测和风险联系起来:华法林与 INR,肝素与 aPTT 和血小板,利尿剂与血钾。
- 选择安全的第一步措施,然后升级处理并重新评估。
公式表、每个专题的关键方法步骤和 16 道练习题,完整解答附在最后。
哪一组副作用是噻嗪类或吲达帕胺等类噻嗪利尿剂的典型副作用?
A patient on three blood pressure drugs still has high readings at every visit. What should the nurse check first?
A patient takes an SGLT2 inhibitor. Which sick-day advice is correct?
An older man was found on the floor after lying there for many hours. His urine is dark brown, and his creatine kinase is very high. What is the main kidney risk and the key treatment?
Which lifestyle change most improves the course of Crohn's disease?
A nurse finds a dislodged sealed radiation source in the bed of a patient receiving brachytherapy. What should the nurse do?
After removing a peripheral IV cannula, what should the nurse check?
An adult with capacity refuses a blood transfusion for religious reasons, even though it may save their life. What should the nurse do?
A patient with recurrent gout starts allopurinol. Which laboratory result shows that the treatment is achieving its goal?
A man of Mediterranean descent develops dark urine, jaundice and a falling hemoglobin a few days after eating fava beans. Which condition is most likely?
某练习血气显示代谢性酸中毒,HCO₃⁻ 10 mmol/L。用温特公式求预期PaCO₂(范围的中心),单位 mmHg。
某练习血气显示呼吸性酸中毒:pH 7.26,PaCO₂ 74 mmHg (9.9 kPa),HCO₃⁻ 32 mmol/L。利用规则“HCO₃⁻ 每 10 mmHg 升高 1 mmol/L(急性)或 3.5 mmol/L(慢性)”进行分类。点选你的答案。
在这条规则的 II 导联心电图上测量 QT 间期和 R–R 间期,然后用 Bazett 公式 QTc = QT/√RR(均以秒计)计算经心率校正的QTc。答案以秒表示,保留三位小数。
这条 II 导联心电图显示房室传导阻滞,所以心房和心室以不同的频率搏动。QRS 波群是规则的:求出心室率(单位:次/分,1500 法,取整数)。
在 START 分诊中,一名不能行走的成人每分钟呼吸 36 次。该伤员被归入哪一类?
After a head injury, a patient passes large amounts of very dilute urine, is thirsty and has a rising serum sodium. Which condition is most likely?
答案: D · 低钾、低钠、尿酸升高和血糖升高
噻嗪类可引起低钾血症、低钠血症、低镁血症、高尿酸血症(痛风)、高血糖和高钙血症(它们减少钙的排泄)。干咳和血管性水肿是 ACE 抑制剂的作用。
答案: B · Whether the patient is taking the medicines as prescribed
Before labelling hypertension as resistant, adherence, measurement technique, white-coat effect and interacting substances (NSAIDs, decongestants, alcohol, liquorice) should be checked. Side effects, cost and complex regimens are common reasons for missed doses.
答案: C · Pause the drug during illness with vomiting or poor intake
During dehydrating illness, SGLT2 inhibitors increase the risk of DKA, which can occur with only modestly raised glucose, and of acute kidney injury. Patients are taught to pause them until they are eating and drinking normally.
答案: B · AKI from rhabdomyolysis, treated with generous IV fluids
Prolonged pressure damages muscle (rhabdomyolysis), releasing myoglobin, which is toxic to the tubules, as well as potassium. Early, generous IV fluids with close monitoring of urine output, potassium and creatinine help protect the kidneys.
答案: D · Stopping smoking
Smoking worsens Crohn's disease, increasing flares, complications and the need for surgery. Stopping smoking is one of the most effective changes a patient can make.
答案: B · Use long-handled forceps to put it in the lead container; report it
A dislodged source is picked up with long-handled forceps and placed in the shielded container kept in the room. The radiation safety officer and team are informed, following local policy.
答案: A · That the cannula is intact, and apply pressure until bleeding stops
The nurse checks that the whole cannula has been removed, applies pressure and a dressing, and records the removal. Any signs of phlebitis are noted.
答案: B · Respect the refusal, check it is informed and document it, and inform the team
An adult with capacity has the right to refuse treatment, even life-saving treatment. The team should make sure the patient understands the consequences, discuss alternatives such as cell salvage and record the decision.
答案: A · A falling serum uric acid
Allopurinol reduces uric acid production by blocking xanthine oxidase. Over time, a lower serum uric acid reduces gout attacks and dissolves urate crystals. Kidney function is checked, and a rash must be reported because of rare severe skin reactions.核对依据: Gout · StatPearls (NCBI Bookshelf) (2026)
答案: A · G6PD deficiency with acute hemolysis
G6PD deficiency makes red cells vulnerable to oxidative damage. Fava beans, some drugs (such as primaquine and some sulfonamides) and infections can trigger acute hemolysis, with dark urine, jaundice and anemia. Triggers are avoided.
答案: PaCO₂ = 23 mmHg
预期代偿:代谢性酸中毒时,温特公式预测 PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg;实测值高于该范围提示合并呼吸性酸中毒,低于该范围提示合并呼吸性碱中毒。阴离子间隙 AG = Na⁺ − (Cl⁻ + HCO₃⁻),正常约为 8–12 mmol/L,用于区分高阴离子间隙与正常阴离子间隙代谢性酸中毒;低白蛋白会掩盖升高的间隙(白蛋白低于 4.0 的部分,每 g/dL 加 2.5)。Δ 比值 (AG − 12)/(24 − HCO₃⁻) 约在 0.8 到 2 之间符合单纯高间隙酸中毒(有些教材用 1 代替 0.8),低于此范围提示合并正常间隙酸中毒,高于 2 提示合并代谢性碱中毒。
答案: 慢性基础上的急性
预期代偿:代谢性酸中毒时,温特公式预测 PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg;实测值高于该范围提示合并呼吸性酸中毒,低于该范围提示合并呼吸性碱中毒。阴离子间隙 AG = Na⁺ − (Cl⁻ + HCO₃⁻),正常约为 8–12 mmol/L,用于区分高阴离子间隙与正常阴离子间隙代谢性酸中毒;低白蛋白会掩盖升高的间隙(白蛋白低于 4.0 的部分,每 g/dL 加 2.5)。Δ 比值 (AG − 12)/(24 − HCO₃⁻) 约在 0.8 到 2 之间符合单纯高间隙酸中毒(有些教材用 1 代替 0.8),低于此范围提示合并正常间隙酸中毒,高于 2 提示合并代谢性碱中毒。
答案: QTc = 0.388 s
QT 与 QTc:QT 间期从 QRS 波群起点到 T 波终点。它随心率加快而缩短,因此要用以秒为单位的 R–R 间期按心率校正:Bazett QTc = QT/√RR,Fridericia QTc = QT/∛RR。多数教科书使用 Bazett 公式;它在心率快时校正过度,此时宜用 Fridericia。各参考标准的界限不同:QTc 男性高于约 0.45 s、女性高于约 0.46 s 通常称为延长,高于 0.50 s 称为明显延长。
在通常上限之内(男性约 0.45 s,女性约 0.46 s)。(388 ms)
答案: 心室率 = 56 bpm
房室传导阻滞:逐个标出 P 波,检查哪些 P 波后面跟着 QRS。一度:每个 P 波都下传,PR 恒定且大于 0.20 s。二度 I 型(Mobitz I,文氏现象):PR 逐搏延长,直到一个 P 波未下传,然后周期重新开始(成组搏动)。二度 II 型(Mobitz II):下传搏动的 PR 保持恒定,P 波突然不下传;QRS 常增宽。三度(完全性)阻滞:P 波和 QRS 波群各自规则但互相独立,PR 随机变化,心房率快于逸搏率(交界性逸搏 40–60 次/分,QRS 窄;室性逸搏 20–40 次/分,QRS 宽)。2:1 阻滞仅凭一份条带无法判断是 I 型还是 II 型。
三度阻滞,伴窄 QRS 交界性逸搏(通常为 40–60 次/分)。
答案: B · 红色(立即)
在 START 中,呼吸频率超过 30 次/分意味着伤员被标为立即(红色)。30 次或以下则继续进行灌注和意识状态检查。
答案: C · Diabetes insipidus
Damage to the pituitary or hypothalamus can stop the release of antidiuretic hormone, causing diabetes insipidus. The patient loses water, so urine is dilute and sodium rises; SIADH causes the opposite.
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