感染控制与患者安全
方法
- 对每位患者都从标准预防开始:手卫生、针对预期暴露的个人防护装备、安全使用锐器。
- 按传播途径追加预防措施:接触传播(隔离衣、手套)、飞沫传播(外科口罩)、空气传播(N95、负压病房)。
- 保持无菌物品的无菌状态:如有疑问就视为不无菌;更换,绝不擦拭。
- 预防环境中的伤害:防跌倒措施,约束仅作为最后手段,火灾时用 RACE 和 PASS。
- 核对给药的正确原则、两个身份识别信息,以及对高警示药物的额外保障;报告差错和险兆事件。
公式表、每个专题的关键方法步骤和 34 道练习题,完整解答附在最后。
Which adverse effect is a particular risk with NSAIDs such as ibuprofen?
Why must medicines for Parkinson's disease, such as levodopa, be given on time?
When should the transparent dressing over a peripheral IV site be changed?
Minutes after the first IV dose of an antibiotic starts, the patient develops wheezing, hives and low blood pressure. What should the nurse do first?
A patient has a new plaster cast that is still drying. How should the nurse handle it?
A patient is bleeding internally after a fall. Which finding is usually an early sign of hypovolemic shock?
Why must levodopa for Parkinson's disease be given at the exact times prescribed in hospital?
一名重症哮喘患者变得安静,出现"沉默肺"、精疲力竭,呼吸频率下降。这表示什么?
一名服用呋塞米的患者钾为 2.9 mEq/L。护士预期会出现哪项发现?
A patient's results: sodium 140 mEq/L, chloride 100 mEq/L, bicarbonate 12 mEq/L. What is the anion gap, and what does it suggest?
A patient receives lactulose for hepatic encephalopathy. Which finding shows that it is working?
哪一对不良反应是长期使用胺碘酮的特征性表现?
After a bronchoscopy with throat anaesthesia, when can the patient eat and drink?
A woman starting rifampicin (rifampin) for tuberculosis uses a combined oral contraceptive pill. What advice is correct?
卒中静脉溶栓后的最初 24 小时内,哪些观察最重要?
A patient with Guillain–Barré syndrome has a blood pressure that swings between 80/50 and 190/100 mmHg and a heart rate that changes suddenly. What does this suggest?
How are skin staples usually removed from a healed incision?
A patient with a sacral pressure ulcer keeps sliding down the bed when the head is raised high. Which advice best reduces shear?
A newborn has flat, blue-grey patches over the lower back and buttocks. How should the nurse interpret this?
A labouring woman feels intense rectal pressure and says "the baby is coming". She was 7 cm 20 minutes ago. What should the nurse do first?
A toddler with hand, foot and mouth disease refuses to drink because of painful mouth sores. What is the priority?
Two children with cystic fibrosis are admitted to the same ward. Which precaution is important?
How does repetitive transcranial magnetic stimulation (rTMS) differ from ECT?
A caller says she is a patient's sister and asks how he is doing. The patient has not given consent to share information. What should the nurse do?
练习题(虚构数值,不作为临床指导)。 一次体重换算得到 92.9715 kg。 本练习的规则是:体重取到最接近的十分之一千克。你记录的数值x是多少?
练习题(虚构数值,不作为临床指导)。 一张处方写着口服混悬液½ tbsp,每天四次,共 14 天。按1 tbsp = 15 mL,整个疗程需要多少 mLV?
一名体重 12 kg 的儿童按 15 mg/kg 处方用药。原液浓度为 20 mg/mL。请抽取剂量:应给多少体积 V?
处方剂量为 465 微克。安瓿浓度为 0.5 mg/mL。请用 1 mL 注射器抽取剂量:应给多少体积 V?
用滴系数为 60 滴/mL 的输液器在 10 小时内输入 250 mL。求滴速 R(滴/分)。
一袋液体在 250 mL 中含药 250 mg,以 10 mL/h 的速度输注。患者每小时获得多少毫克 D?
练习题(虚构数值,不作为临床指导)。 记录显示了一名患者在一个 8 小时班次中的出入量。静脉输液在整个班次中按所示速率输注。求总入量 I,以 mL 计。 冰屑按其体积的一半计。
练习题(虚构数值,不作为临床指导)。 一袋 500 mL 的液体于 08:15 开始用输液泵以 120 mL/h 输注。到 11:15 时袋中还剩多少 mL V?
练习题(虚构数值,不作为临床指导)。 一张练习图表记录了 GCS 9,其中 E2 和 V3。记录的运动评分M是多少,它描述的是哪种反应?请给出数字。
练习题(虚构数值,不作为临床指导)。 用 Morse 跌倒评分评估一位练习患者:过去 3 个月内的跌倒史: 否; 次要诊断: 否; 行走辅助: 拐杖、手杖或助行器; 静脉输液或封管: 否; 步态: 虚弱; 精神状态: 了解自身局限。使用分界值 0–24 低,25–44 中度,45 或以上高,点击跌倒风险等级。
答案: B · Stomach irritation and bleeding
NSAIDs can irritate the stomach lining and cause ulcers and bleeding. They are taken with food, avoided in some patients and may also affect the kidneys.
答案: A · Late doses can cause severe stiffness, falls and swallowing problems
Levodopa wears off quickly, and delays can cause rigidity, falls, swallowing difficulty and aspiration. It is a time-critical medicine in hospital.
答案: C · When it is damp, loose or visibly soiled
A dressing that is wet, loose or dirty no longer protects the insertion site and is changed using aseptic technique. Otherwise, it is changed according to policy.
答案: A · Stop the infusion
These are signs of anaphylaxis. The nurse stops the infusion at once, calls for help and supports the airway, and intramuscular epinephrine (adrenaline) is the first-line treatment. Documentation comes later.
答案: A · With the palms of the hands, not the fingertips
A wet plaster cast can be dented by fingertips, causing pressure points under the cast. It is handled with the palms, supported on pillows and left uncovered to dry.
答案: A · Restlessness and a rising heart rate while the blood pressure is still normal
In early shock, the body keeps the blood pressure up by raising the heart rate and narrowing vessels, so restlessness and tachycardia appear first. A falling blood pressure is a later sign.
答案: B · Delays can quickly worsen rigidity, immobility and swallowing
Levodopa has a short effect, so missed or late doses can lead to severe stiffness, falls, swallowing problems and, rarely, a dangerous hyperpyrexia-like state. Parkinson's medicines are treated as time-critical.
答案: A · 危及生命的哮喘,即将发生呼吸停止
沉默肺、精疲力竭、发绀和意识混乱都是危及生命的征象。患者需要上级医生和危重症团队立即介入。
答案: C · 肌肉无力和腿部抽筋
低钾引起肌肉无力、抽筋、肠蠕动减弱(便秘,甚至肠麻痹)和心律失常。T 波高尖见于高钾血症,口周麻刺感提示低钙。核对依据: Heart failure - fluids and diuretics · MedlinePlus (NIH); Low blood potassium · MedlinePlus (NIH) (2025)
答案: C · 28 mEq/L, a high anion gap
The anion gap is 140 − (100 + 12) = 28 mEq/L; a typical normal value is about 8–12 mEq/L when potassium is not included. A high anion gap metabolic acidosis suggests unmeasured acids, for example ketones in DKA or lactate in shock.核对依据: Anion Gap Blood Test · MedlinePlus (NIH) (2024)
答案: B · Better alertness and orientation, with two to three soft stools a day
Lactulose is adjusted to give about two to three soft stools a day and to lower ammonia, improving mental status. Excessive diarrhoea can cause dehydration and electrolyte loss.
答案: C · 甲状腺功能异常和肺纤维化
胺碘酮富含碘并在组织中蓄积,可引起甲状腺功能减退或亢进、肺纤维化、肝损伤、光敏感和角膜沉积。其他几对分别符合氨基糖苷类、苯妥英和 ACE 抑制剂。
答案: C · When the gag and cough reflexes have returned
Local anaesthetic sprayed on the throat abolishes the gag and cough reflexes for a time, so food or fluid could be aspirated. The nurse checks that the reflexes have returned (often after about one to two hours) before giving sips of water and then food.
答案: C · Use another reliable method, as rifampicin reduces the pill's effect
Rifampicin induces liver enzymes that break down oestrogen and progestogen, so hormonal contraception may fail. A non-hormonal or unaffected method, such as a copper IUD, is advised during and for a time after treatment. The interaction also affects warfarin and many other drugs.
答案: B · 频繁的神经系统检查和血压
溶栓后应频繁进行神经系统观察、血压测量和出血检查。新出现的头痛、呕吐、GCS 下降或血压升高可能提示出血。通常 24 小时内避免使用抗血小板药和抗凝药。
答案: C · Autonomic dysfunction, which needs continuous cardiac monitoring
Guillain–Barré syndrome can involve autonomic nerves, causing labile blood pressure and dangerous arrhythmias. Patients need continuous ECG monitoring and close observation, often in a high-dependency setting.
答案: A · Alternate staples first, then the rest if the wound holds
Removing alternate staples first allows the nurse to check that the wound edges stay together. If the wound is secure, the rest are removed, and adhesive strips can be applied for support.
答案: B · Keep the head of the bed at or below 30° if possible; use slide sheets
A high head position makes patients slide, causing shear on the sacrum. A lower head position when clinically possible, knee break or foot support, and slide sheets for moving reduce shear and friction.
答案: D · Harmless dermal melanocytosis, to be documented
Congenital dermal melanocytosis (Mongolian spots) are harmless and usually fade over years. They should be documented clearly so they are not mistaken later for bruises.
答案: A · Check whether the head is visible and stay with her
A strong urge to push and rectal pressure suggest full dilation or imminent birth. The nurse stays, checks for crowning, calls for help and prepares for birth. Opioids close to birth can depress the newborn's breathing.
答案: C · Preventing dehydration
Hand, foot and mouth disease, usually caused by coxsackievirus, is self-limiting. The main risk is dehydration from painful mouth ulcers, so cool fluids, soft foods and analgesia are given and wet nappies are monitored.
答案: D · Keep them apart, not sharing rooms, equipment or play areas
People with CF can pass bacteria such as Pseudomonas aeruginosa and Burkholderia cepacia to each other, worsening lung disease. Children with CF are kept apart in hospital and clinics, and equipment is not shared.
答案: A · It uses magnetic pulses on the scalp while the patient is awake, without causing a seizure
rTMS stimulates specific brain areas with a magnetic coil held on the head. It does not need anaesthesia or cause a seizure and is used for depression that has not responded to medicines.
答案: A · Neither confirm nor deny that he is there, and offer to pass on a message
Without the patient's consent, the nurse should not disclose that a person is receiving mental health care. Offering to pass on a message respects confidentiality while allowing the patient to decide.
答案: x = 93 kg
取整:看舍入位后面的那个数字:5 或更大则进位,4 或更小则保持原数字不变。只对最终答案取整,绝不对中间步骤取整。典型的考试规则:1 mL 或以上的体积取到十分位,低于 1 mL 的体积取到百分位,滴速取整到整滴,体重取到一位小数;务必遵循题目所规定的规则。
答案: V = 420 mL
量纲分析:先写出已知量,再乘以写成分数形式的换算系数(例如 60 min/1 h 或 1 mg/1000 mcg),使每个不需要的单位在分子和分母各出现一次并相互约去。只剩下所求单位时再计算。使用题目给出的等量关系,只对最终答案取整。
答案: V = 9 mL
抽取剂量:体积 = (处方剂量/药物浓度) × 药物体积。先换算成相同的单位,再检查该体积是否适合注射器,并落在它的某一个刻度上。
在这支 10 mL 的注射器上,每条小刻度线代表 0.2 mL。
答案: V = 0.93 mL
抽取剂量:体积 = (处方剂量/药物浓度) × 药物体积。先换算成相同的单位,再检查该体积是否适合注射器,并落在它的某一个刻度上。
答案: R = 25 gtt/min
输注速率:输液泵按 mL/h = 体积/时间(小时)设定。重力滴注按每分钟滴数计:gtt/min = 体积 (mL) × 滴系数 (gtt/mL)/时间 (min)。 滴系数印在输液器包装上:普通输液器为 10、15 或 20 gtt/mL(输血器在美国常为 10 gtt/mL,在英国为 15),微量输液器为 60 gtt/mL。务必使用题目或包装给出的滴系数。
答案: D = 10 mg/h
输注速率:输液泵按 mL/h = 体积/时间(小时)设定。重力滴注按每分钟滴数计:gtt/min = 体积 (mL) × 滴系数 (gtt/mL)/时间 (min)。 滴系数印在输液器包装上:普通输液器为 10、15 或 20 gtt/mL(输血器在美国常为 10 gtt/mL,在英国为 15),微量输液器为 60 gtt/mL。务必使用题目或包装给出的滴系数。
答案: I = 1280 mL
出入量:入量计入所有进入体内的液体(口服液体、静脉输液、静脉用药及冲管液、管饲);冰屑按其体积的一半计。出量计入尿液、引流液、呕吐物和其他丢失。平衡 = 总入量 − 总出量;平衡为负表示净丢失。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: V = 140 mL
输液时间:时间 (h) = 待输体积 (mL)/速率 (mL/h);使用袋中剩余的体积,而不是袋的容量。已输入体积 = 速率 × 时间。把小数小时换算为小时和分钟时,用小数部分 × 60(0.5 h = 30 min,而不是 50 min)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: M = 4
格拉斯哥昏迷量表:把三个方面的最佳反应相加。睁眼 E:4 自发,3 对声音或言语,2 对压迫,1 无。言语 V:5 定向正常,4 意识模糊,3 用词不恰当,2 发出无法理解的声音,1 无。运动 M:6 遵嘱动作,5 定位,4 正常屈曲(回缩),3 异常屈曲,2 伸展,1 无。总分为 3 至 15。头部损伤后,13–15 通常称为轻度,9–12 为中度,3–8 为重度。
答案: 中度风险
Morse 跌倒评分:六个条目。跌倒史:否 0 分,是 25 分。次要诊断:否 0 分,是 15 分。行走辅助:无、卧床休息或护士协助 0 分;拐杖、手杖或助行器 15 分;扶着家具 30 分。静脉输液或封管:否 0 分,是 20 分。步态:正常、卧床休息或轮椅 0 分;虚弱 10 分;受损 20 分。精神状态:了解自身局限 0 分;高估或忘记自身局限 15 分。总分为 0 至 125。各医院的风险分界值不同;常用的一套是 0–24 低风险,25–44 中度风险,45 及以上为高风险。
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