感染控制与患者安全
方法
- 对每位患者都从标准预防开始:手卫生、针对预期暴露的个人防护装备、安全使用锐器。
- 按传播途径追加预防措施:接触传播(隔离衣、手套)、飞沫传播(外科口罩)、空气传播(N95、负压病房)。
- 保持无菌物品的无菌状态:如有疑问就视为不无菌;更换,绝不擦拭。
- 预防环境中的伤害:防跌倒措施,约束仅作为最后手段,火灾时用 RACE 和 PASS。
- 核对给药的正确原则、两个身份识别信息,以及对高警示药物的额外保障;报告差错和险兆事件。
公式表、每个专题的关键方法步骤和 34 道练习题,完整解答附在最后。
Using the AVPU scale, a patient who opens their eyes and groans only when the nurse squeezes their shoulder is scored as:
For a patient at risk of pressure ulcers, why is the head of the bed usually kept at 30 degrees or less if their condition allows?
Many intensive care units bathe patients daily with chlorhexidine. What is the main purpose?
A patient with suspected sepsis has orders for blood cultures and an IV antibiotic. What is the correct order of actions?
RN 将哪项任务委派给 LPN/LVN 最为恰当?
Four patients arrive at the emergency department at the same time. Who should be seen first?
Which examination findings suggest a large pleural effusion on one side?
After a head injury, a patient has clear fluid leaking from the nose. What does this most likely suggest?
A pregnant woman's blood type is O Rh-negative, and her antibody screen (indirect Coombs test) is negative. What is usually offered at about 28 weeks?
A patient with chronic kidney disease stage 4 has a high phosphate, a low-normal calcium and a very high parathyroid hormone (PTH). What does this show?
一名患者有严重肾功能损害。某药物主要以原形经尿排泄。通常如何调整?
有些受体即使没有激动剂也表现出活性。在这类受体上,反向激动剂与中性拮抗剂有何不同?
Why should a long-acting beta-2 agonist (LABA) never be used alone in asthma?
A 74-year-old with atrial fibrillation, hypertension and diabetes asks why she needs an anticoagulant when she feels well. Which reply is best?
Why is IV calcium gluconate given in severe hyperkalaemia?
An adult stares blankly for about a minute, smacks their lips and fumbles with their clothes. Afterwards they are confused for ten minutes and remember nothing. Which seizure type fits best?
Why is a pregnancy test often done before surgery in women who could be pregnant?
Just after extubation in recovery, a patient develops a high-pitched noise on breathing in, with falling SpO₂. What should the nurse do first?
Why is mild anaemia common in the second trimester even in healthy women?
A woman at 37 weeks has severe itching of the palms and soles, worse at night, without a rash. Which condition should be considered?
钳捏抓握(用拇指和食指捏起小物体)通常在大约多大时发育出来?
A baby born at 27 weeks has grunting, chest retractions and rising oxygen needs. Which treatment directly addresses the cause?
A patient who started lithium 2 weeks ago has a fine tremor of the hands and is passing more urine than usual. Her level is within the therapeutic range. How should the nurse interpret this?
Which intervention is most appropriate for an older patient with delirium?
练习题(虚构数值,不作为临床指导)。 一位患者身高 4 ft 1 in。按 1 ft = 12 in 和 1 in = 2.54 cm,求以厘米表示的身高h,取到最接近的整厘米。
练习题(虚构数值,不作为临床指导)。 一张处方写着口服混悬液2 tsp,每天四次,共 14 天。混悬液每瓶 100 mL。按1 tsp = 5 mL,必须提供多少整瓶N才能完成疗程?
一名体重 7 kg 的儿童按 10 mg/kg 处方用药。原液浓度为 25 mg/mL。请抽取剂量:应给多少体积 V?
一名体重 18 kg 的儿童,医嘱为口服混悬液每次 10 mg/kg,该混悬液每 5 mL 含 100 mg。你应给多少体积 V?
滴注以 35 gtt/min 的速度通过滴系数为 20 gtt/mL 的输液器。患者在 2 小时内接受多少毫升 V?
25 mg 药物溶于 250 mL 的输液以 15 mL/h 运行。患者每分钟接受多少微克 D?
练习题(虚构数值,不作为临床指导)。 记录显示了一名患者在一个 8 小时班次中的出入量。静脉输液在整个班次中按所示速率输注。求总入量 I,以 mL 计。
练习题(虚构数值,不作为临床指导)。 一袋 500 mL 的液体用输液泵以 150 mL/h 输注。到 11:30 时已输入 100 mL。还要多少小时 t 袋子才会输完? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 对这些观察结果使用 NEWS2 图表(SpO₂ 量表 1):呼吸频率 20 次/分,SpO₂ 96%吸室内空气,血压 118/70 mmHg,脉搏 58 次/分,清醒,体温 38.1 °C。NEWS2 总分是多少?
练习题(虚构数值,不作为临床指导)。 团队的目标是平均动脉压至少为 70 mmHg。一位患者的收缩压为 116 mmHg。使用 MAP = (SBP + 2·DBP)/3,仍能使 MAP 达到 70 mmHg 的最低舒张压DBP是多少?
答案: D · P
AVPU stands for Alert, responds to Voice, responds to Pain, Unresponsive. A response only to a painful stimulus is "P", a serious sign that needs urgent review.
答案: D · Higher angles make the patient slide down, causing shear over the sacrum
When the head is raised high, the body tends to slide while the skin stays still, distorting the tissues over the sacrum. Keeping the angle low, where safe, reduces this shear.
答案: A · To reduce skin bacteria and bloodstream infections linked to central lines
Daily chlorhexidine bathing lowers the number of organisms on the skin, reducing central line-associated bloodstream infections and the spread of resistant bacteria in ICUs.
答案: A · Draw the blood cultures first, then give the antibiotic without delay
Cultures are drawn before the first antibiotic dose so the organism can still be grown and identified. The antibiotic is then given promptly, because delay increases the risk of death in sepsis.
答案: B · 为病情稳定的患者置入留置导尿管
为病情稳定的患者置入导尿管是常在 LPN/LVN 范围内的技能。入院评估、初次教育和开始输血通常仍由 RN 负责。具体范围因州和国家而异。
答案: D · An older adult with weakness on one side that began 40 minutes ago
Sudden one-sided weakness suggests a stroke, and treatment depends on how quickly it starts. Severe kidney stone pain needs prompt pain relief, but the patient is stable.
答案: C · Dull percussion and reduced breath sounds over the lung base
Fluid in the pleural space muffles breath sounds and makes percussion stony dull. A large effusion may push the trachea away from the affected side.
答案: A · A base-of-skull fracture with a cerebrospinal fluid leak
Clear fluid from the nose or ear after head injury suggests a CSF leak from a skull base fracture, with a risk of meningitis. Nasal tubes and nose-blowing should be avoided and the patient reviewed urgently.
答案: C · Anti-D immunoglobulin (Rho(D) immune globulin)
An Rh-negative mother can form anti-D antibodies if Rh-positive fetal blood enters her circulation, which can cause hemolytic disease in a later pregnancy. Anti-D immunoglobulin at about 28 weeks and after delivery of an Rh-positive baby prevents this sensitization.核对依据: Red Blood Cell Antibody Screen · MedlinePlus (NIH) (2025); Hemolytic disease of the newborn · MedlinePlus (NIH) (2025)
答案: D · Secondary hyperparathyroidism from CKD
In CKD, phosphate retention and reduced activation of vitamin D lower calcium, which stimulates the parathyroid glands. The result is high PTH with high phosphate, causing bone disease. Phosphate binders, diet and active vitamin D are used.核对依据: Parathyroid Hormone (PTH) Test · MedlinePlus (NIH) (2023)
答案: C · 减少剂量或延长给药间隔
肾清除率下降时,经肾排泄的药物会蓄积。应根据肾功能并尽可能根据血药浓度降低剂量或减少给药频次。
答案: C · 它使活性降到基础水平以下
中性拮抗剂只是阻断激动剂,基础活性不变。反向激动剂稳定受体的非活性状态,因此组成性活性降到基础水平以下。
答案: D · Without an inhaled steroid, it is linked with severe and fatal attacks
LABA monotherapy in asthma is linked with severe attacks and asthma deaths because it relieves symptoms while airway inflammation continues. In asthma, LABAs are always given with an inhaled corticosteroid, often in one combination inhaler.
答案: D · Her risk of stroke is high, and an anticoagulant lowers it
In AF, blood stasis in the left atrium causes clots that can travel to the brain. Scores such as CHA₂DS₂-VASc (age, hypertension, diabetes, female sex and others) estimate stroke risk; her score is high. Anticoagulation reduces stroke risk but does not change the rhythm.
答案: D · It protects the heart from arrhythmias
Calcium stabilises the cardiac cell membrane and reduces the risk of arrhythmias within minutes. It does not change the potassium level, so other treatments are needed to shift and remove potassium.
答案: B · Focal impaired awareness seizure
Focal impaired awareness seizures often come from the temporal lobe. They last about a minute or two, with automatisms such as lip smacking and fumbling, and are followed by confusion. Absence seizures are shorter and have no postictal phase.
答案: A · Anaesthesia, drugs and some tests may harm a fetus
Unknown pregnancy can change the decision to operate, the timing, and the choice of drugs and X-rays. Testing is offered with consent, according to local policy.
答案: B · Call for help, give 100% oxygen and use a jaw thrust
Stridor after extubation suggests laryngospasm or another upper airway obstruction. The nurse calls for help, applies high-flow oxygen and airway manoeuvres, and the anaesthetist may give drugs or reintubate.
答案: B · Plasma volume rises more than red cell mass
Plasma volume increases more than red cell mass, so haemoglobin concentration falls (physiological or dilutional anaemia). Iron deficiency can add to this and should still be checked.
答案: B · Intrahepatic cholestasis of pregnancy
Itching of the hands and feet without a rash suggests intrahepatic cholestasis of pregnancy. Raised bile acids are linked with stillbirth, so liver function and bile acids are checked and timing of birth may be planned.
答案: B · 约 9 至 10 个月
钳捏抓握通常在约 9–10 个月时出现,到约 12 个月时变得灵巧精细。这也是这个年龄小物体成为窒息风险的原因。
答案: D · Surfactant given into the trachea
Respiratory distress syndrome in preterm babies is caused by surfactant deficiency. Exogenous surfactant given via the airway, with respiratory support such as CPAP, improves lung compliance. Antibiotics are often started too, because infection can look similar.
答案: C · These are common side effects that are not by themselves signs of toxicity, but they should be reported and monitored
Fine tremor, thirst, polyuria and mild nausea are common early effects of lithium. A coarse tremor, vomiting, diarrhoea, confusion or unsteadiness suggest toxicity.
答案: A · Provide orientation cues, make sure glasses and hearing aids are used, and involve the family
Non-drug measures, such as clocks and calendars, sensory aids, a normal sleep-wake cycle, mobility, hydration and familiar people, help while the underlying cause is treated. Restraints and frequent moves worsen delirium.
答案: h = 124 cm
家用计量和体重:护理考试使用取整的等量关系:1 茶匙(tsp)= 5 mL,1 汤匙(tbsp)= 15 mL = 3 tsp,1 液量盎司(fl oz)= 30 mL = 2 tbsp,1 杯 = 8 fl oz = 240 mL。体重方面,1 kg = 2.2 lb,1 lb = 16 oz;长度方面,1 英寸 = 2.54 cm。设置换算时,要让你不需要的单位相互约去。
答案: N = 6
量纲分析:先写出已知量,再乘以写成分数形式的换算系数(例如 60 min/1 h 或 1 mg/1000 mcg),使每个不需要的单位在分子和分母各出现一次并相互约去。只剩下所求单位时再计算。使用题目给出的等量关系,只对最终答案取整。
答案: V = 2.8 mL
抽取剂量:体积 = (处方剂量/药物浓度) × 药物体积。先换算成相同的单位,再检查该体积是否适合注射器,并落在它的某一个刻度上。
在这支 10 mL 的注射器上,每条小刻度线代表 0.2 mL。
答案: V = 9 mL
剂量计算:给药量等于医嘱剂量除以现有药物的规格,再乘以该规格对应的量:给药量 = (医嘱剂量/储备规格) × 储备体积。始终统一单位(先把 g 换成 mg,mg 换成 mcg),并检查答案是否合理。
答案: V = 210 mL
Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.
答案: D = 25 mcg/min
Dose-based infusions: concentration = amount of drug in the bag/bag volume. Pump rate (mL/h) = dose per hour/concentration, and dose per hour = mL/h × concentration. Convert per-minute doses to per-hour (× 60) and keep the mass units the same (1 g = 1000 mg, 1 mg = 1000 mcg).
答案: I = 800 mL
出入量:入量计入所有进入体内的液体(口服液体、静脉输液、静脉用药及冲管液、管饲);冰屑按其体积的一半计。出量计入尿液、引流液、呕吐物和其他丢失。平衡 = 总入量 − 总出量;平衡为负表示净丢失。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: t = 2.7 h
输液时间:时间 (h) = 待输体积 (mL)/速率 (mL/h);使用袋中剩余的体积,而不是袋的容量。已输入体积 = 速率 × 时间。把小数小时换算为小时和分钟时,用小数部分 × 60(0.5 h = 30 min,而不是 50 min)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
约为 2 h 40 min,所以袋子大约在 14:10 输完。
答案: NEWS2 = 1
NEWS2(国家早期预警评分 2,英国皇家内科医师学会 2017):按图表为七个参数分别评分(呼吸频率、量表 1 的 SpO₂、吸空气还是吸氧、收缩压、脉搏、按 ACVPU 量表评定的意识状态和体温),然后把分数相加。临床风险:0–4 为低;任何单项参数得 3 分为中低;5–6 为中;7 或以上为高。总分 5 或以上需要紧急响应。
答案: DBP = 47 mmHg
血压数值:脉压 PP = SBP − DBP。平均动脉压 MAP ≈ (SBP + 2·DBP)/3 = DBP + PP/3,这是基于正常心率下心脏每搏约有三分之二时间处于舒张期的估算(心率快时准确性下降);MAP 至少约 65 mmHg 是常用的器官灌注目标。休克指数 SI = 心率/SBP,正常约为 0.5–0.7;高于约 1 是休克的警示信号。
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