感染控制与患者安全
方法
- 对每位患者都从标准预防开始:手卫生、针对预期暴露的个人防护装备、安全使用锐器。
- 按传播途径追加预防措施:接触传播(隔离衣、手套)、飞沫传播(外科口罩)、空气传播(N95、负压病房)。
- 保持无菌物品的无菌状态:如有疑问就视为不无菌;更换,绝不擦拭。
- 预防环境中的伤害:防跌倒措施,约束仅作为最后手段,火灾时用 RACE 和 PASS。
- 核对给药的正确原则、两个身份识别信息,以及对高警示药物的额外保障;报告差错和险兆事件。
公式表、每个专题的关键方法步骤和 34 道练习题,完整解答附在最后。
Which patient is at greatest risk of injury from a heat pack?
On the sacrum there is a shallow open area with a pink wound bed and no slough. How is this pressure ulcer classified?
A confused patient keeps pulling at an IV line. Which is a less restrictive option to consider before wrist restraints?
During a procedure, a nurse sees that the team is about to start without a time-out. What should the nurse do?
Five days after starting heparin, a patient’s platelet count has fallen by more than half. What should the nurse suspect?
A dehydrated child is to receive IV fluids with added potassium. Which finding should the nurse confirm first?
世卫组织三阶梯镇痛原则建议:
A catheterised postoperative patient has passed only 10 mL of urine in the last two hours. What should the nurse check first?
哪种治疗通过使钾进入细胞内来降低血清钾?
A patient on clozapine reports a sore throat and fever. The ANC is 400/µL (0.4 × 10⁹/L). What should the nurse do?
Why should NSAIDs be used with caution in some people with asthma?
In myxoedema coma, why is hydrocortisone often given before or with thyroid hormone?
What is the main problem in heart failure with preserved ejection fraction?
A patient with a confirmed type A aortic dissection is hypertensive and tachycardic while awaiting surgery. Which drug class is usually given first to lower the heart rate and blood pressure?
A patient with atrial fibrillation has had an ischaemic stroke. Which long-term medicine type most reduces the risk of another stroke?
一名患者的慢性低钠血症在 24 小时内从 115 纠正到 132 mmol/L。两天后他们出现言语含糊、吞咽困难和肢体无力。最可能的原因是什么?
Which measure helps reduce the risk of delirium in an older surgical patient?
On day 3 after admission, a patient with alcohol dependence becomes confused, with hallucinations, sweating, tremor, fever and tachycardia. What is the most likely cause?
A woman is about to get out of bed for the first time after birth. What should the nurse do?
A woman with postpartum psychosis is being admitted with her baby to a mother and baby unit. Which statement is accurate?
Which sign shows that a baby is ready to start solid foods?
Which child is most appropriate to assign to a practical (enrolled) nurse?
A patient taking sertraline wants to take ibuprofen regularly for arthritis. What should the nurse teach?
A man is found in a city far from home. He cannot remember who he is or how he got there, but his speech and thinking are otherwise normal. Tests show no head injury or intoxication. What is most likely?
练习题(虚构数值,不作为临床指导)。 一个剂量记录在 08:10(24 小时制)。哪个条目是 12 小时制中的同一时间?点击它。
练习题(虚构数值,不作为临床指导)。 一次输注的给药速率为 2 mg/h。请把这个剂量速率D用 mcg/min 表示。取到一位小数。
某患者体重 22 kg。医嘱剂量为每天 15 mg/kg,分 4 次等量给药。每次给多少毫克 D?
处方为 400 单位的药物,药液规格为 1000 单位/mL。请用 1 mL 注射器抽取剂量:应给多少体积 V?
滴注以 25 gtt/min 的速度通过滴系数为 15 gtt/mL 的输液器。患者在 12 小时内接受多少毫升 V?
将 500 mg 药物稀释于 250 mL 中,通过滴系数为 60 gtt/mL 的输液器重力滴注。医嘱为每小时 150 mg。求滴速 R,以每分钟滴数表示。
练习题(虚构数值,不作为临床指导)。 记录显示了一名患者在一个 12 小时班次中的出入量。患者体重 52 kg。求平均尿量 U,以 mL/kg/h 计。 保留两位小数。
练习题(虚构数值,不作为临床指导)。 一份 1000 mL 的输液于 10:00 开始以 150 mL/h 输注。4 小时后速率改为 80 mL/h,之后不再改变。从开始算起多少小时 t 后袋子会输完? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 对这些观察结果使用 NEWS2 图表(SpO₂ 量表 1):呼吸频率 12 次/分,SpO₂ 96%吸室内空气,血压 96/58 mmHg,脉搏 98 次/分,清醒,体温 37.6 °C。NEWS2 总分是多少?
练习题(虚构数值,不作为临床指导)。 出生后 5 分钟,一名练习用新生儿的表现为:躯干粉红,手脚青紫,心率 135 次/分,刺激时做鬼脸,四肢略有屈曲,呼吸缓慢、不规则,哭声微弱。 为 Apgar 评分并点击该评分的解读。
答案: B · A patient with reduced sensation from diabetic neuropathy
Patients who cannot feel heat properly, such as those with neuropathy, spinal injury or reduced consciousness, can be burned without noticing. Their skin needs extra checks or heat should be avoided.
答案: A · Category 2
Category 2 (Stage 2 in the US NPIAP system) is partial-thickness skin loss, seen as a shallow open ulcer with a pink-red bed or as a blister. Category 1 is intact skin; categories 3 and 4 are full thickness.
答案: B · Covering the site with a sleeve or using hand mitts with supervision
Covering the line, keeping it out of view and using mitts while observing the patient can stop pulling without fully restricting movement. Restraints and sedation are used only if these fail.
答案: D · Speak up clearly and stop the start until the time-out is done
The time-out is a key step to prevent wrong-patient, wrong-site and wrong-procedure errors. Any team member who sees it being skipped should speak up and halt the procedure until it is done.
答案: A · Heparin-induced thrombocytopenia
Heparin-induced thrombocytopenia usually appears 5–10 days after starting heparin, with a large fall in platelets and a risk of clotting. The nurse reports at once so heparin can be stopped.
答案: C · That the child is passing urine
Potassium is not added to IV fluids until the child is passing urine, because poor kidney function can let potassium build up to dangerous levels.
答案: B · 随着疼痛加重,从非阿片类药物逐步升级到弱阿片类,再到强阿片类
阶梯从非阿片类药物(如对乙酰氨基酚)到弱阿片类,再到强阿片类,每一阶梯都可加用辅助药物。对于持续性疼痛,首选按时给药。
答案: D · That the catheter and tubing are not kinked or blocked
A sudden fall in catheter output may be due to a kinked, clamped or blocked catheter. If it is draining freely, the nurse assesses fluid status and vital signs and escalates possible hypovolaemia or AKI.
答案: A · 静脉注射普通胰岛素并配合葡萄糖
胰岛素激活钠–钾泵,使钾进入细胞内;同时给予葡萄糖以预防低血糖。葡萄糖酸钙保护心脏,但不降低钾水平。核对依据: High potassium level · MedlinePlus (NIH) (2025)
答案: D · Hold the clozapine and report the result at once
An ANC below 500/µL is severe neutropenia, and with fever and sore throat it suggests a serious infection. Clozapine is held, the provider is told immediately, and infection is assessed and treated. A nurse never changes a dose without a prescription.
答案: A · They can trigger bronchospasm in aspirin-sensitive asthma
In aspirin-exacerbated respiratory disease, COX inhibition increases leukotriene production, causing bronchospasm. These patients should avoid aspirin and other non-selective NSAIDs.
答案: D · Thyroid hormone can trigger adrenal crisis if cortisol is also low
Restoring thyroid hormone increases metabolic rate and cortisol clearance. If adrenal reserve is also low, this can precipitate adrenal crisis, so steroid cover is given until adrenal insufficiency is excluded.
答案: D · A stiff ventricle that fills poorly in diastole
In HFpEF, the left ventricle is stiff and relaxes poorly, so filling pressures rise and cause congestion even though the ejection fraction is normal. It is common in older people with hypertension, diabetes and obesity. HFrEF is mainly a problem of contraction.
答案: A · An intravenous beta-blocker
In acute dissection, IV beta-blockers are usually given first to reduce heart rate and the rate of rise of pressure, limiting extension of the tear. Vasodilators may follow once the heart rate is controlled. Antiplatelets, anticoagulants and thrombolytics are avoided. Type A dissection needs urgent surgery.
答案: C · An oral anticoagulant
In AF the main cause of stroke is a clot from the left atrium. Oral anticoagulants such as a DOAC or warfarin prevent this far better than antiplatelets. The start date after a stroke depends on its size and bleeding risk.
答案: D · 渗透性脱髓鞘综合征
慢性低钠血症的快速纠正会使脑细胞皱缩,并可损伤脑桥和其他区域的髓鞘。症状(构音障碍、吞咽困难、四肢轻瘫、“闭锁”状态)在数天后出现。这就是为什么要限制纠正速度并密切监测血钠。
答案: A · Making sure they have their glasses and hearing aids
Delirium prevention includes using glasses and hearing aids, orientation, good sleep, hydration, nutrition, early mobilisation, pain control, avoiding unnecessary sedatives and involving family.
答案: A · Delirium tremens from alcohol withdrawal
Delirium tremens usually develops 2–3 days after stopping alcohol and is a medical emergency. It is treated with benzodiazepines, fluids, thiamine and close monitoring, ideally prevented by a withdrawal protocol.
答案: B · Help her sit, then stand slowly with support
Orthostatic hypotension is common after birth. The nurse helps her sit at the edge of the bed, dangle her legs, then stand slowly with assistance and stays close in case she feels faint.
答案: D · It is an emergency that usually starts within two weeks
Postpartum psychosis is rare but serious, typically starting suddenly within the first two weeks with mania, confusion, hallucinations or delusions. Bipolar disorder is a major risk factor. Urgent treatment is needed to keep mother and baby safe.
答案: C · Sits with support, holds the head steady and shows interest in food
Readiness for solids, usually around 6 months, includes good head control, sitting with support, interest in food and loss of the tongue-thrust reflex. Night waking and teething are not signs of readiness.
答案: D · A 7-year-old 2 days after an appendicectomy, stable on oral analgesia
Practical or enrolled nurses usually care for stable children with predictable outcomes. Children who are unstable, newly admitted with a complex condition or showing signs of deterioration need a registered nurse's assessment.
答案: C · The combination increases the risk of bleeding, especially in the stomach, so discuss it with the prescriber
SSRIs reduce serotonin uptake into platelets, which impairs clotting. Combined with NSAIDs, aspirin or anticoagulants, the risk of gastrointestinal bleeding rises.
答案: B · Dissociative amnesia with dissociative fugue
In dissociative fugue, the person travels away and cannot recall their identity or past, usually after a stressful event. Medical causes such as head injury, seizures and substances must be ruled out first.
答案: 8:10 AM
24 小时制:下午 1 点起,小时数加 12(下午 3:45 = 15:45)。午夜到凌晨 12:59 为 00:00–00:59,中午 12:00–12:59 仍为 12:00–12:59。反过来换算时,13–23 点减 12 并标为下午;00 点变为凌晨 12 点。跨午夜计算时间要分两段:先算到 24:00(00:00),再从 00:00 算起。
答案: D = 33.3 mcg/min
量纲分析:先写出已知量,再乘以写成分数形式的换算系数(例如 60 min/1 h 或 1 mg/1000 mcg),使每个不需要的单位在分子和分母各出现一次并相互约去。只剩下所求单位时再计算。使用题目给出的等量关系,只对最终答案取整。
答案: D = 82.5 mg
剂量计算:给药量等于医嘱剂量除以现有药物的规格,再乘以该规格对应的量:给药量 = (医嘱剂量/储备规格) × 储备体积。始终统一单位(先把 g 换成 mg,mg 换成 mcg),并检查答案是否合理。
答案: V = 0.4 mL
抽取剂量:体积 = (处方剂量/药物浓度) × 药物体积。先换算成相同的单位,再检查该体积是否适合注射器,并落在它的某一个刻度上。
在这支 1 mL 的注射器上,每条小刻度线代表 0.01 mL。
答案: V = 1200 mL
Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.
答案: R = 75 gtt/min
Dose-based infusions: concentration = amount of drug in the bag/bag volume. Pump rate (mL/h) = dose per hour/concentration, and dose per hour = mL/h × concentration. Convert per-minute doses to per-hour (× 60) and keep the mass units the same (1 g = 1000 mg, 1 mg = 1000 mcg).
答案: U = 1.68 mL/kg/h
出入量:入量计入所有进入体内的液体(口服液体、静脉输液、静脉用药及冲管液、管饲);冰屑按其体积的一半计。出量计入尿液、引流液、呕吐物和其他丢失。平衡 = 总入量 − 总出量;平衡为负表示净丢失。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: t = 9 h
输液时间:时间 (h) = 待输体积 (mL)/速率 (mL/h);使用袋中剩余的体积,而不是袋的容量。已输入体积 = 速率 × 时间。把小数小时换算为小时和分钟时,用小数部分 × 60(0.5 h = 30 min,而不是 50 min)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
约为 9 h 00 min,所以袋子大约在 19:00 输完。
答案: NEWS2 = 3
NEWS2(国家早期预警评分 2,英国皇家内科医师学会 2017):按图表为七个参数分别评分(呼吸频率、量表 1 的 SpO₂、吸空气还是吸氧、收缩压、脉搏、按 ACVPU 量表评定的意识状态和体温),然后把分数相加。临床风险:0–4 为低;任何单项参数得 3 分为中低;5–6 为中;7 或以上为高。总分 5 或以上需要紧急响应。
答案: 中度异常
Apgar 评分:五项体征,每项评 0、1 或 2 分,在出生后 1 分钟和 5 分钟检查。外观(肤色):青紫或苍白 0 分,躯干粉红、四肢青紫 1 分,全身粉红 2 分。脉搏:无 0 分,低于 100 次/分 1 分,100 次/分或以上 2 分。反射(反射应激性):无 0 分,做鬼脸 1 分,哭叫、咳嗽或打喷嚏 2 分。肌张力(活动):松软 0 分,略有屈曲 1 分,活动活跃 2 分。呼吸:无 0 分,缓慢或不规则、哭声微弱 1 分,良好、哭声响亮 2 分。总分 7–10 为令人放心,4–6 为中度异常,0–3 为低。
5 分钟时低于 7 分,通常每 5 分钟重复评分一次,直至 20 分钟。
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