感染控制与患者安全
方法
- 对每位患者都从标准预防开始:手卫生、针对预期暴露的个人防护装备、安全使用锐器。
- 按传播途径追加预防措施:接触传播(隔离衣、手套)、飞沫传播(外科口罩)、空气传播(N95、负压病房)。
- 保持无菌物品的无菌状态:如有疑问就视为不无菌;更换,绝不擦拭。
- 预防环境中的伤害:防跌倒措施,约束仅作为最后手段,火灾时用 RACE 和 PASS。
- 核对给药的正确原则、两个身份识别信息,以及对高警示药物的额外保障;报告差错和险兆事件。
公式表、每个专题的关键方法步骤和 34 道练习题,完整解答附在最后。
When should blood cultures be taken in a patient with suspected sepsis?
Aspirate from a newly placed nasogastric tube has a pH of 7. What should the nurse do?
Which practice reduces back strain when a nurse moves a patient or heavy object?
A patient restrained because of violent behavior is now calm, oriented and following instructions. What should the nurse do?
A parent calls to say their toddler has just swallowed drain cleaner. What should the nurse advise?
An infant is choking and cannot cry or breathe. Which technique is correct?
一名术后患者心率 125 次/分,血压 88/50 mmHg,敷料被血浸透。发生了什么?
一名输注肝素的患者在开始五天后血小板突然下降。应怀疑什么?
Which instruction is correct for a patient starting oral iron tablets?
一名慢性肾脏病患者磷酸盐为 7.2 mg/dL(2.3 mmol/L)。哪项饮食指导最恰当?
氯吡格雷如何减少血小板聚集?
Why is clavulanic acid combined with amoxicillin (co-amoxiclav)?
Rheumatic heart disease most often follows which infection?
A patient with severe chronic kidney disease needs therapeutic anticoagulation for a DVT. Why might unfractionated heparin be chosen instead of a low-molecular-weight heparin?
The day after a thyroidectomy, a patient reports tingling around the mouth and in the fingers. Why might this happen?
A nurse teaches foot care to a patient with diabetic neuropathy. Which statement shows a need for further teaching?
Which risk is particularly linked with tramadol?
Hours after an oesophageal dilatation, a patient has chest pain, fever and crackling swelling under the skin of the neck. What should the nurse suspect?
一名妊娠 32 周、已知有前置胎盘的女性因出血入院。必须避免哪项操作?
A newborn has cyanosis that improves when crying and worsens during feeding. Which condition should be suspected?
Which diet is usually recommended for a child with cystic fibrosis?
A baby born to a mother who used opioids in pregnancy has a high-pitched cry, tremors, sneezing and poor feeding. Which plan is best?
Which psychological treatment is most effective for obsessive-compulsive disorder?
A patient taking naltrexone for alcohol dependence is brought to the emergency department with a broken leg. Why should the nurse tell the team about the naltrexone?
练习题(虚构数值,不作为临床指导)。 一次注射的剂量计算得到 2.9824 mL。 本练习的规则是:1 mL 或以上的体积取到最接近的十分之一 mL。你记录的数值x是多少?
练习题(虚构数值,不作为临床指导)。 一张处方写着口服混悬液½ tsp,每 6 小时一次,共 14 天。混悬液每瓶 150 mL。按1 tsp = 5 mL,必须提供多少整瓶N才能完成疗程?
2 mL 的 2%(w/v)溶液中含有多少毫克药物 m?
一袋输液在 500 mL 中含 25000 单位药物。医嘱为每小时 500 单位。泵速 R 应设为多少 mL/h?
滴注以 30 gtt/min 的速度通过滴系数为 15 gtt/mL 的输液器。患者在 6 小时内接受多少毫升 V?
一袋液体在 500 mL 中含药 250 mg,以 30 mL/h 的速度输注。患者每小时获得多少毫克 D?
练习题(虚构数值,不作为临床指导)。 记录显示了一名患者在一个 12 小时班次中的出入量。患者体重 90 kg。求平均尿量 U,以 mL/kg/h 计。 保留两位小数。
练习题(虚构数值,不作为临床指导)。 一袋 500 mL 的液体用输液泵以 80 mL/h 输注。到 21:00 时已输入 200 mL。还要多少小时 t 袋子才会输完? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 用 Morse 跌倒评分评估一位练习患者:过去 3 个月内的跌倒史: 是; 次要诊断: 是; 行走辅助: 拐杖、手杖或助行器; 静脉输液或封管: 否; 步态: 受损; 精神状态: 高估或忘记自身局限。求 Morse 总分MFS。
练习题(虚构数值,不作为临床指导)。 对这些观察结果使用 NEWS2 图表(SpO₂ 量表 1):呼吸频率 12 次/分,SpO₂ 99%吸室内空气,血压 90/54 mmHg,脉搏 76 次/分,清醒,体温 37.3 °C。患者属于哪个临床风险组?点击它。
答案: A · Before antibiotics are given, as long as this does not delay them
Taking cultures first gives the best chance of identifying the organism. They are collected with strict asepsis, but antibiotics must not be delayed in sepsis.
答案: B · Not use the tube and follow policy, which may mean a chest X-ray
A low pH supports gastric placement (1–5.5 in UK guidance; 5 or below is typical in US guidance). A pH of 7 does not rule out the lungs, so nothing is put down the tube until position is confirmed, usually by X-ray. The "whoosh" air test is unreliable.
答案: A · Keep the load close to the body and avoid twisting
Good body mechanics include a wide base of support, bending at the hips and knees, keeping the load close and turning with the feet instead of twisting the spine. Lifting aids are used whenever possible.
答案: C · Remove the restraints, because the reason for them has ended
Restraints are used only as long as needed to keep people safe. Once the patient no longer presents a danger, the restraints are removed, even if the order has not yet expired.
答案: A · Do not make the child vomit; call poison control or emergency services now
Inducing vomiting after a corrosive is swallowed causes more burns to the throat and risks aspiration. The parent should get expert advice and emergency help at once.
答案: B · Back blows and chest thrusts
For a choking infant, the nurse gives cycles of five back blows and five chest thrusts. Abdominal thrusts are not used in infants, and blind finger sweeps can push the object deeper.
答案: C · 出血导致的低血容量性休克
心动过速、低血压加上可见的失血提示失血性(低血容量性)休克。应压迫止血、紧急呼救,并准备补液或输血。
答案: B · 肝素诱导的血小板减少症
HIT 通常在开始使用肝素 5–10 天后出现,血小板下降超过 50%,并有血栓风险。应停用肝素,改用非肝素类抗凝药。
答案: A · Your stools may turn dark green or black
Oral iron commonly darkens the stools, which is harmless, but black tarry stools with abdominal pain should be reported. Milk, antacids and tea reduce absorption; vitamin C or orange juice can improve it.核对依据: Ferrograd C patient information leaflet (ferrous sulfate + vitamin C) · electronic medicines compendium (eMC), UK (2018)
答案: C · 限制富含磷酸盐的食物,如加工食品和可乐
CKD 中的高磷通过限制磷摄入、随餐服用结合剂和透析来处理。含有磷酸盐添加剂的加工食品、可乐和大量乳制品是主要来源。核对依据: Phosphorus: Tips for People with Chronic Kidney Disease · Indian Health Service (HHS); Phosphorus and Your Kidneys · National Kidney Foundation (2024); Chronic kidney disease · MedlinePlus (NIH) (2025)
答案: C · 阻断血小板上的 ADP 受体 P2Y12
氯吡格雷在肝脏中被激活,不可逆地阻断血小板上的 P2Y12 ADP 受体。心肌梗死或支架植入后,它常与阿司匹林联用。
答案: D · It inhibits beta-lactamase enzymes that would destroy amoxicillin
Many bacteria produce beta-lactamases that inactivate penicillins. Clavulanic acid inhibits these enzymes, so amoxicillin can work against these organisms.
答案: D · A group A streptococcal throat infection
Rheumatic fever is an autoimmune reaction weeks after group A streptococcal pharyngitis. It can permanently damage heart valves, most often the mitral valve. Prompt antibiotic treatment of strep throat prevents it.
答案: C · LMWH is cleared by the kidneys and can accumulate
Low-molecular-weight heparins are mainly renally excreted, so they accumulate in severe renal impairment and increase bleeding risk. Unfractionated heparin is cleared mainly by other routes, has a short half-life and can be monitored with aPTT and reversed with protamine.
答案: D · The parathyroid glands may have been damaged, lowering calcium
The parathyroid glands lie behind the thyroid and can be damaged or removed during surgery. Low PTH leads to hypocalcaemia, causing tingling, cramps and, if severe, tetany or arrhythmias. Calcium is checked after surgery.
答案: C · "I will buy corn plasters from the pharmacy for my corn."
Medicated corn plasters contain acids that can burn the skin and cause ulcers in people with neuropathy or poor circulation. Corns and calluses should be treated by a podiatrist.
答案: C · Serotonin syndrome with some antidepressants, and seizures
Tramadol is a weak opioid that also inhibits serotonin and noradrenaline reuptake. It can lower the seizure threshold and cause serotonin syndrome with SSRIs and other serotonergic drugs.
答案: D · Oesophageal perforation
Chest pain, fever and surgical (subcutaneous) emphysema after instrumentation suggest oesophageal perforation, which can cause mediastinitis. The patient is kept nil by mouth and reviewed urgently; CT confirms it.
答案: C · 阴道指诊
阴道指诊可能扰动低置的胎盘并导致严重出血。监护、静脉通路、血液检查和超声检查都是合适的。
答案: D · Choanal atresia
In choanal atresia, the nasal passages are blocked. Babies breathe through the mouth when crying, but become cyanotic when feeding or calm. A catheter cannot be passed through the nose.
答案: B · A high-energy, high-fat diet with fat-soluble vitamin supplements
Children with CF need more energy than usual because of malabsorption and the work of breathing. A high-energy diet with enzymes and extra vitamins A, D, E and K is standard; extra salt may be needed.
答案: D · Low-stimulation care, swaddling, small frequent feeds and a withdrawal scoring tool
Neonatal abstinence (withdrawal) is managed first with calm, low-stimulation care, swaddling, frequent feeds and support for parents, with regular scoring to guide any drug treatment. Naloxone is avoided because it can trigger acute withdrawal and seizures.
答案: C · Exposure and response prevention, a form of CBT
In exposure and response prevention, the patient is gradually exposed to the anxiety-provoking trigger and resists the compulsion. Anxiety falls over time without the ritual, weakening the cycle. SSRIs are the main medicines used.
答案: C · Naltrexone blocks opioid analgesics, so pain relief needs to be planned differently
Naltrexone blocks opioid receptors, so usual opioid doses may not work, and attempts to overcome the block with high doses can be dangerous. The team needs to know so that analgesia can be planned safely.
答案: x = 3 mL
取整:看舍入位后面的那个数字:5 或更大则进位,4 或更小则保持原数字不变。只对最终答案取整,绝不对中间步骤取整。典型的考试规则:1 mL 或以上的体积取到十分位,低于 1 mL 的体积取到百分位,滴速取整到整滴,体重取到一位小数;务必遵循题目所规定的规则。
答案: N = 1
量纲分析:先写出已知量,再乘以写成分数形式的换算系数(例如 60 min/1 h 或 1 mg/1000 mcg),使每个不需要的单位在分子和分母各出现一次并相互约去。只剩下所求单位时再计算。使用题目给出的等量关系,只对最终答案取整。
答案: m = 40 mg
Solution strengths: a percentage strength is grams per 100 mL, so 1% = 1 g/100 mL = 10 mg/mL. A ratio strength 1:1000 means 1 g in 1000 mL = 1 mg/mL; 1:10 000 is 0.1 mg/mL. For a dilution the amount of drug stays the same: C₁·V₁ = C₂·V₂.
答案: R = 10 mL/h
剂量计算:给药量等于医嘱剂量除以现有药物的规格,再乘以该规格对应的量:给药量 = (医嘱剂量/储备规格) × 储备体积。始终统一单位(先把 g 换成 mg,mg 换成 mcg),并检查答案是否合理。
答案: V = 720 mL
Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.
答案: D = 15 mg/h
输注速率:输液泵按 mL/h = 体积/时间(小时)设定。重力滴注按每分钟滴数计:gtt/min = 体积 (mL) × 滴系数 (gtt/mL)/时间 (min)。 滴系数印在输液器包装上:普通输液器为 10、15 或 20 gtt/mL(输血器在美国常为 10 gtt/mL,在英国为 15),微量输液器为 60 gtt/mL。务必使用题目或包装给出的滴系数。
答案: U = 1.06 mL/kg/h
出入量:入量计入所有进入体内的液体(口服液体、静脉输液、静脉用药及冲管液、管饲);冰屑按其体积的一半计。出量计入尿液、引流液、呕吐物和其他丢失。平衡 = 总入量 − 总出量;平衡为负表示净丢失。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: t = 3.8 h
输液时间:时间 (h) = 待输体积 (mL)/速率 (mL/h);使用袋中剩余的体积,而不是袋的容量。已输入体积 = 速率 × 时间。把小数小时换算为小时和分钟时,用小数部分 × 60(0.5 h = 30 min,而不是 50 min)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
约为 3 h 45 min,所以袋子大约在 00:45 输完。
答案: MFS = 90
Morse 跌倒评分:六个条目。跌倒史:否 0 分,是 25 分。次要诊断:否 0 分,是 15 分。行走辅助:无、卧床休息或护士协助 0 分;拐杖、手杖或助行器 15 分;扶着家具 30 分。静脉输液或封管:否 0 分,是 20 分。步态:正常、卧床休息或轮椅 0 分;虚弱 10 分;受损 20 分。精神状态:了解自身局限 0 分;高估或忘记自身局限 15 分。总分为 0 至 125。各医院的风险分界值不同;常用的一套是 0–24 低风险,25–44 中度风险,45 及以上为高风险。
答案: 中低
NEWS2(国家早期预警评分 2,英国皇家内科医师学会 2017):按图表为七个参数分别评分(呼吸频率、量表 1 的 SpO₂、吸空气还是吸氧、收缩压、脉搏、按 ACVPU 量表评定的意识状态和体温),然后把分数相加。临床风险:0–4 为低;任何单项参数得 3 分为中低;5–6 为中;7 或以上为高。总分 5 或以上需要紧急响应。
即使总分低,单项得 3 分也需要紧急会诊。
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