感染控制与患者安全
方法
- 对每位患者都从标准预防开始:手卫生、针对预期暴露的个人防护装备、安全使用锐器。
- 按传播途径追加预防措施:接触传播(隔离衣、手套)、飞沫传播(外科口罩)、空气传播(N95、负压病房)。
- 保持无菌物品的无菌状态:如有疑问就视为不无菌;更换,绝不擦拭。
- 预防环境中的伤害:防跌倒措施,约束仅作为最后手段,火灾时用 RACE 和 PASS。
- 核对给药的正确原则、两个身份识别信息,以及对高警示药物的额外保障;报告差错和险兆事件。
公式表、每个专题的关键方法步骤和 34 道练习题,完整解答附在最后。
A patient with a weak left leg walks with a stick in the right hand. What is the correct sequence?
Before giving a PRN dose of oral morphine, which assessment is most important?
A patient is on suicide precautions. Which room safety measure is appropriate?
A patient restrained because of violent behavior is now calm, oriented and following instructions. What should the nurse do?
A nurse teaches a patient with COPD pursed-lip breathing. Which statement shows a need for further teaching?
Which patient finding after a total knee replacement needs the nurse’s action first?
Which is a recognised risk factor for postoperative nausea and vomiting?
A patient has a swollen, warm, tender calf on one side. Which action should the nurse avoid?
A patient is scheduled for a liver biopsy. Which laboratory results should the nurse check before the procedure?
A patient with sepsis has the following new results. Which set best shows organ dysfunction?
Which teaching about zolpidem is correct?
A patient on disulfiram becomes flushed, nauseated and has palpitations after using a mouthwash. What is the most likely cause?
A patient choosing between a mechanical and a biological heart valve asks about the main difference. Which answer is accurate?
A day after a myocardial infarction, a patient has frequent ventricular ectopic beats on the monitor. Which blood results should be checked first?
A patient's potassium stays low despite replacement. Which other level should be checked?
A patient with a head injury now has a blood pressure of 190/70 mmHg, a pulse of 48/min and irregular breathing. How should the nurse interpret this?
Which diet is usually recommended for a patient with cirrhosis and hepatic encephalopathy?
Why is folinic acid (leucovorin) given after high-dose methotrexate?
Why is it important to do newborn bloodspot screening at the recommended time rather than in the first hours?
A woman at 8 weeks takes valproate for epilepsy. She asks whether she should stop it. Which response is best?
一名儿童在同一次就诊时需要接种几种不同的疫苗。一般原则是什么?
Which statement by the parent of a child with peanut allergy shows a need for further teaching?
A 78-year-old woman who started citalopram two weeks ago is newly confused and drowsy. Which laboratory result would best explain this?
一名处于躁狂发作的患者在活动室里打断其他患者并且声音越来越大。最恰当的护理措施是什么?
练习题(虚构数值,不作为临床指导)。 一次注射的剂量计算得到 6.1212 mL。 本练习的规则是:1 mL 或以上的体积取到最接近的十分之一 mL。你记录的数值x是多少?
练习题(虚构数值,不作为临床指导)。 一次输注从 22:15 开始,到次日早晨 05:25 结束(24 小时制)。它运行了多少分钟t?
一名体重 28 kg 的儿童按 2.5 mg/kg 处方用药。原液浓度为 50 mg/mL。请抽取剂量:应给多少体积 V?
处方剂量为 1.52 mg。安瓿每 mL 含 2000 微克。请用 1 mL 注射器抽取剂量:应给多少体积 V?
用滴系数为 10 滴/mL 的输液器在 8 小时内输入 1000 mL。求滴速 R(滴/分)。 取整到最接近的整数。
一组输液以 32 滴/分的速度经 20 滴/mL 的输液器滴注。袋中还剩 200 mL。还需多少小时 t 才会滴完? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 记录显示了一名患者在一个 12 小时班次中的出入量。静脉输液在整个班次中按所示速率输注。求液体平衡 B = 入量 − 出量,以 mL 计(答案为负表示净丢失)。
练习题(虚构数值,不作为临床指导)。 一袋 500 mL 的液体用输液泵以 50 mL/h 输注。到 07:00 时已输入 150 mL。还要多少小时 t 袋子才会输完? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 一位患者的脉搏为 127 次/分,血压为 164/90 mmHg。求休克指数SI = HR/SBP。取到两位小数。
练习题(虚构数值,不作为临床指导)。 一名成人体重 86 kg,身高 151 cm。计算 BMI 并点击 WHO 体重分类。
答案: A · Move the stick and the left leg forward together, then the right leg
The stick and the weak leg move together so the stick takes part of the load, then the strong leg steps through.
答案: C · The respiratory rate and level of sedation
Opioids can cause sedation and respiratory depression. Checking breathing and alertness before each dose, as well as the pain score, keeps the patient safe.
答案: A · Remove items that could be used for self-harm, such as belts and cords
Patients at risk of suicide need a safe environment, with belts, cords, sharp objects and glass removed, and observation at the level ordered. Privacy is secondary to safety in this situation.
答案: C · Remove the restraints, because the reason for them has ended
Restraints are used only as long as needed to keep people safe. Once the patient no longer presents a danger, the restraints are removed, even if the order has not yet expired.
答案: B · “I will breathe in through my mouth and out quickly through my nose.”
Pursed-lip breathing means breathing in through the nose and out slowly through pursed lips, making exhalation longer. This keeps airways open and reduces air trapping.
答案: B · Sudden calf pain and swelling in the operated leg, with new breathlessness
Calf pain and swelling suggest deep vein thrombosis, and new breathlessness raises concern for a pulmonary embolism. This needs immediate assessment and escalation; the other findings are expected.
答案: B · Use of opioids after surgery
Known risk factors include opioids, female sex, being a non-smoker, previous PONV or motion sickness and longer general anaesthetics. High-risk patients may be given preventive antiemetics.
答案: D · Massaging the calf
Unilateral calf swelling and tenderness suggests DVT. Massaging the leg is avoided in case it dislodges the clot; the patient needs medical review and investigation.
答案: A · Platelet count and PT/INR
Liver biopsy carries a risk of bleeding, and liver disease often lowers platelets and clotting factors. Platelets and PT/INR are checked beforehand, and abnormal results are reported so they can be corrected or the procedure postponed.核对依据: Liver biopsy · MedlinePlus (NIH) (2025)
答案: A · Platelets 70 × 10³/µL, creatinine doubled, bilirubin raised
In sepsis, falling platelets (coagulation), a rising creatinine (kidney) and a raised bilirubin (liver) show organ dysfunction, which indicates severe disease. The other sets are normal or near normal.核对依据: Bacterial Sepsis · StatPearls (NCBI Bookshelf) (2023); Laboratory Evaluation of Sepsis · StatPearls (NCBI Bookshelf) (2023)
答案: D · Take it right before bed, only if you can sleep a full night
Zolpidem can cause next-day impairment and complex sleep behaviours such as sleep-walking or sleep-driving. Alcohol and other sedatives increase these risks.
答案: D · Alcohol in the mouthwash caused a disulfiram–alcohol reaction
Disulfiram reactions can occur with small amounts of alcohol in mouthwash, cough syrups, sauces or aftershave. Patients are taught to check labels and avoid all alcohol-containing products.
答案: B · Mechanical valves last longer but need lifelong anticoagulation
Mechanical valves are very durable but are thrombogenic, so lifelong warfarin is needed. Biological (tissue) valves usually do not need long-term anticoagulation but wear out over time and may need replacement. Age, lifestyle and bleeding risk guide the choice.
答案: D · Potassium and magnesium
Low potassium and low magnesium both increase ventricular irritability and the risk of VT and VF after an MI. They are checked and corrected, usually keeping potassium in the upper part of the normal range. The patient is also assessed for ischaemia and haemodynamic change.
答案: C · Magnesium
Hypomagnesaemia increases potassium loss in the urine and makes hypokalaemia hard to correct. Magnesium is checked and replaced as well.
答案: B · Cushing's triad, a late sign of raised intracranial pressure
Cushing's triad is hypertension with a widening pulse pressure, bradycardia and irregular respiration. It shows that the brainstem is being compressed and herniation may be imminent, so it is an emergency.
答案: C · Normal protein and enough calories, with a late-evening snack
Protein restriction worsens malnutrition and muscle loss and is no longer routinely advised. Adequate protein and energy, small frequent meals and a late-evening snack are recommended.
答案: B · To rescue normal cells from methotrexate toxicity
Methotrexate inhibits dihydrofolate reductase. Timed folinic acid bypasses this block in normal cells, reducing toxicity such as mucositis and myelosuppression, while methotrexate levels and kidney function are monitored.
答案: B · Some results, such as PKU, need milk feeds first
Phenylalanine builds up only after the baby has had milk feeds, so very early samples can miss PKU. Programmes specify timing, and early samples may need repeating.
答案: A · Do not stop it suddenly; arrange urgent specialist review
Valproate is strongly teratogenic, but stopping antiepileptics suddenly can cause seizures that harm mother and fetus. She needs urgent specialist review to change treatment safely, ideally before conception.
答案: D · 可以在同一次就诊时接种,选择不同的注射部位
一次就诊接种几种疫苗是安全有效的,并可避免延误。应使用不同的注射器和部位,如在同一肢体,至少相距约 2.5 cm。除非产品是专门设计的,否则切勿混合疫苗。
答案: C · "If she has a bad reaction, I'll give an antihistamine and wait an hour before using the auto-injector."
Adrenaline is the first treatment for anaphylaxis and must be given without delay; antihistamines do not treat airway swelling or shock. Checking expiry dates, reading labels and calling emergency services after use are correct.
答案: A · A low serum sodium
SSRIs can cause hyponatraemia through SIADH, especially in older adults. Confusion, falls and drowsiness after starting an SSRI should prompt a sodium check.
答案: C · 平静地引导患者到刺激较少、较安静的区域,并设定清晰、简单的限制
躁狂患者受益于平静、低刺激的环境、坚定而一致的限制,以及简单、非竞争性的活动。
答案: x = 6.1 mL
取整:看舍入位后面的那个数字:5 或更大则进位,4 或更小则保持原数字不变。只对最终答案取整,绝不对中间步骤取整。典型的考试规则:1 mL 或以上的体积取到十分位,低于 1 mL 的体积取到百分位,滴速取整到整滴,体重取到一位小数;务必遵循题目所规定的规则。
答案: t = 430 min
24 小时制:下午 1 点起,小时数加 12(下午 3:45 = 15:45)。午夜到凌晨 12:59 为 00:00–00:59,中午 12:00–12:59 仍为 12:00–12:59。反过来换算时,13–23 点减 12 并标为下午;00 点变为凌晨 12 点。跨午夜计算时间要分两段:先算到 24:00(00:00),再从 00:00 算起。
答案: V = 1.4 mL
抽取剂量:体积 = (处方剂量/药物浓度) × 药物体积。先换算成相同的单位,再检查该体积是否适合注射器,并落在它的某一个刻度上。
在这支 10 mL 的注射器上,每条小刻度线代表 0.2 mL。
答案: V = 0.76 mL
抽取剂量:体积 = (处方剂量/药物浓度) × 药物体积。先换算成相同的单位,再检查该体积是否适合注射器,并落在它的某一个刻度上。
答案: R = 21 gtt/min
输注速率:输液泵按 mL/h = 体积/时间(小时)设定。重力滴注按每分钟滴数计:gtt/min = 体积 (mL) × 滴系数 (gtt/mL)/时间 (min)。 滴系数印在输液器包装上:普通输液器为 10、15 或 20 gtt/mL(输血器在美国常为 10 gtt/mL,在英国为 15),微量输液器为 60 gtt/mL。务必使用题目或包装给出的滴系数。
床旁取最接近的整滴:21 滴/分。
答案: t = 2.1 h
输注速率:输液泵按 mL/h = 体积/时间(小时)设定。重力滴注按每分钟滴数计:gtt/min = 体积 (mL) × 滴系数 (gtt/mL)/时间 (min)。 滴系数印在输液器包装上:普通输液器为 10、15 或 20 gtt/mL(输血器在美国常为 10 gtt/mL,在英国为 15),微量输液器为 60 gtt/mL。务必使用题目或包装给出的滴系数。
答案: B = 1150 mL
出入量:入量计入所有进入体内的液体(口服液体、静脉输液、静脉用药及冲管液、管饲);冰屑按其体积的一半计。出量计入尿液、引流液、呕吐物和其他丢失。平衡 = 总入量 − 总出量;平衡为负表示净丢失。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
为正:摄入的液体多于排出的液体。
答案: t = 7 h
输液时间:时间 (h) = 待输体积 (mL)/速率 (mL/h);使用袋中剩余的体积,而不是袋的容量。已输入体积 = 速率 × 时间。把小数小时换算为小时和分钟时,用小数部分 × 60(0.5 h = 30 min,而不是 50 min)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
约为 7 h 00 min,所以袋子大约在 14:00 输完。
答案: SI = 0.77
血压数值:脉压 PP = SBP − DBP。平均动脉压 MAP ≈ (SBP + 2·DBP)/3 = DBP + PP/3,这是基于正常心率下心脏每搏约有三分之二时间处于舒张期的估算(心率快时准确性下降);MAP 至少约 65 mmHg 是常用的器官灌注目标。休克指数 SI = 心率/SBP,正常约为 0.5–0.7;高于约 1 是休克的警示信号。
高于通常的 0.5–0.7。
答案: 肥胖 II 级
体质指数:BMI = 体重(kg)/身高(m)²,身高要先换算为米。使用磅和英寸时,BMI = 703 × 体重(lb)/身高(in)²。WHO 成人分类:低于 18.5 为体重过轻,18.5–24.9 为健康体重,25.0–29.9 为超重,30.0–34.9 为肥胖 I 级,35.0–39.9 为肥胖 II 级,40 及以上为肥胖 III 级。
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