感染控制与患者安全
方法
- 对每位患者都从标准预防开始:手卫生、针对预期暴露的个人防护装备、安全使用锐器。
- 按传播途径追加预防措施:接触传播(隔离衣、手套)、飞沫传播(外科口罩)、空气传播(N95、负压病房)。
- 保持无菌物品的无菌状态:如有疑问就视为不无菌;更换,绝不擦拭。
- 预防环境中的伤害:防跌倒措施,约束仅作为最后手段,火灾时用 RACE 和 PASS。
- 核对给药的正确原则、两个身份识别信息,以及对高警示药物的额外保障;报告差错和险兆事件。
公式表、每个专题的关键方法步骤和 34 道练习题,完整解答附在最后。
一名患者几乎不会说英语。在重要的知情同意谈话中,应由谁来翻译?
A patient has been taught breathing exercises before surgery. Which statement shows a need for further teaching?
戴无菌手套时,护士应如何戴上第二只手套?
A 2-year-old living in a house built many decades ago has anemia, irritability and poor appetite. Which cause should the nurse suspect?
A patient has heart failure. Which instruction about daily weights is best to give the nursing assistant?
A patient with a head injury has a pupil on one side that is now large and does not react to light. What should the nurse do?
Which side effect of regular opioids usually needs preventive treatment from the start?
A patient has a blood pressure of 220/130 mmHg with headache, confusion and visual disturbance. Why is the blood pressure lowered in a controlled way rather than as fast as possible?
How often is the INR usually checked when warfarin is first started?
A patient with diabetes had a glucose of 58 mg/dL (3.2 mmol/L), took 15 g of fast-acting carbohydrate and, 15 minutes later, the glucose is 64 mg/dL (3.6 mmol/L). The patient is alert. What should the nurse do next?
华法林的作用机制是:
为什么正在使用硝酸酯类药物治疗心绞痛的患者禁用西地那非?
A patient takes both digoxin and furosemide. Why does the nurse watch the potassium level closely?
On day 2 after a surgical tracheostomy, the tube falls out. The patient is breathing but distressed. What should the nurse do first?
A patient uses a continuous glucose monitor. Which statement is correct?
Two days after surgery, an 80-year-old woman is quiet, sleepy, slow to answer and eating little. Her daughter says she is "not herself". What should the nurse suspect?
Which presentation fits acute diverticulitis?
一名肺癌患者出现面部肿胀、颈静脉怒张,平卧时呼吸困难加重。可能是哪种急症?
A pregnant woman asks why she needs a whooping cough (pertussis) vaccine in pregnancy. Which answer is correct?
妊娠 38 周时,一名女性打电话说,自昨天起胎儿的活动比平时少得多。最佳建议是什么?
Which signs suggest meningitis in a young infant?
一名儿童因发热、颈部僵硬和压之不褪色的皮疹入院。优先事项是什么?
What is the key difference between factitious disorder and malingering?
A patient on daily methadone maintenance has had abdominal surgery. Which statement about his pain management is correct?
练习题(虚构数值,不作为临床指导)。 一位患者身高 169 cm。按 1 in = 2.54 cm,求以英寸表示的身高h。取到一位小数。
练习题(虚构数值,不作为临床指导)。 一次输注从 19:50 开始,到次日早晨 08:45 结束(24 小时制)。它运行了多少小时t?答案以小数表示小时数,取到两位小数。
一支肾上腺素预充式注射器标示为 1:10 000(0.1 mg/mL)。医嘱为心脏骤停时 1 mg 静脉注射(IV)。你应给多少体积 V?
一名体重 14 kg 的儿童,医嘱为口服混悬液每次 12.5 mg/kg,该混悬液每 5 mL 含 250 mg。你应给多少体积 V?
医嘱要求以 60 mL/h 输液,但没有输液泵。改用滴系数为 10 gtt/mL 的输液器重力滴注。求滴速 R,以每分钟滴数表示。
100 mg 药物溶于 250 mL 的输液以 10 mL/h 运行。患者每分钟接受多少微克 D?
练习题(虚构数值,不作为临床指导)。 记录显示了一名患者在一个 12 小时班次中的出入量。静脉输液在整个班次中按所示速率输注。求总入量 I,以 mL 计。 冰屑按其体积的一半计。
练习题(虚构数值,不作为临床指导)。 一袋 1000 mL 的液体用输液泵以 60 mL/h 输注。到 07:30 时已输入 800 mL。还要多少小时 t 袋子才会输完? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 一位患者的脉搏为 67 次/分,血压为 118/65 mmHg。求休克指数SI = HR/SBP。取到两位小数。
练习题(虚构数值,不作为临床指导)。 团队的目标是平均动脉压至少为 65 mmHg。一位患者的收缩压为 85 mmHg。使用 MAP = (SBP + 2·DBP)/3,仍能使 MAP 达到 65 mmHg 的最低舒张压DBP是多少?
答案: A · 专业的医疗口译员
专业口译员能准确翻译并保守秘密。家庭成员,尤其是孩子,可能遗漏内容、加入自己的看法,或因这些信息而承受负担。
答案: C · "I'll avoid coughing so I don't hurt my stitches."
Avoiding coughing lets secretions collect and raises the risk of chest infection. Splinting the wound, deep breathing and good pain control are correct.
答案: C · 将已戴手套的手指插入第二只手套的袖口下面并拉上
第一只手套只能用裸手接触其袖口的内面。已戴手套的手随后只接触第二只手套的外面,即翻折袖口的下方。手套内面一旦接触皮肤就不再无菌。
答案: B · Lead poisoning from old paint dust or chips
Lead-based paint in older housing is the main source of lead exposure in young children, who put dust and chips in their mouths. Lead can cause anemia, behavior changes and developmental problems, and a blood lead level confirms it.
答案: A · “Weigh him each morning before breakfast, on the same scale, and tell me the result.”
Daily weights are measured at the same time, on the same scale and in similar clothing so that changes show real fluid gain. A quick rise in weight can be an early sign of worsening heart failure.
答案: C · Report it at once, as it may mean the brain is being compressed
A newly fixed, dilated pupil suggests pressure on the third cranial nerve from rising intracranial pressure or a bleed. It is a neurological emergency that needs immediate escalation.
答案: A · Constipation
Opioids slow gut movement, and constipation persists with long-term use. A regular laxative is usually prescribed together with the opioid.
答案: C · A sudden drop can reduce blood flow to the brain, heart and kidneys
In a hypertensive emergency, autoregulation in vital organs is reset to higher pressures. Lowering BP too fast can cause ischaemia, so it is reduced gradually under close monitoring.
答案: A · Every few days, until it is stable
When warfarin is started or its dose changes, the INR is checked frequently (often every few days) until it is stable in the target range. After that, the interval can be extended, often up to every 4 weeks or longer if very stable.
答案: D · Give another 15 g of fast carbohydrate and recheck
The "15-15 rule" is repeated until the glucose is at least 70 mg/dL (3.9 mmol/L); UK guidance uses 4.0 mmol/L and 15–20 g of carbohydrate. Then a snack or meal with complex carbohydrate and protein is given if the next meal is not soon, to prevent recurrence.
答案: C · 阻断维生素 K 依赖性凝血因子的合成
华法林抑制维生素 K 环氧化物还原酶,减少因子 II、VII、IX 和 X 的合成。用 INR 监测,用维生素 K 逆转。
答案: C · 两者都升高血管平滑肌中的 cGMP,可能引起严重低血压
硝酸酯类通过一氧化氮增加 cGMP 的生成,西地那非阻断 PDE5 对其的分解。两者合用会导致过度血管扩张和血压危险地下降。
答案: A · Low potassium increases the risk of digoxin toxicity
Digoxin binds to the Na⁺/K⁺-ATPase pump at the site potassium normally uses. When potassium is low, more digoxin binds, so toxicity and arrhythmias become more likely. Loop diuretics commonly cause hypokalaemia, so the combination needs monitoring.
答案: A · Call for expert help and give oxygen to both the face and the stoma
In the first days after a tracheostomy, the tract is immature and the tube can easily be misplaced into the tissues. Emergency guidance is to call for an airway expert, apply oxygen to face and stoma and assess breathing. Reinsertion is done only by trained staff.
答案: C · It reads glucose in fluid under the skin, a little behind blood glucose
CGM sensors measure interstitial glucose, which lags several minutes behind blood glucose, especially when levels change fast. A finger-prick check is advised when symptoms do not match the reading.
答案: A · Hypoactive delirium
Hypoactive delirium presents with drowsiness, withdrawal and slowness rather than agitation, so it is often missed. It has a worse prognosis than the hyperactive form. A family report of a sudden change is important, and a screening tool such as the 4AT or the CAM (Confusion Assessment Method) can be used.
答案: C · Left lower abdominal pain, fever and a raised CRP
Diverticulitis usually causes left iliac fossa pain and tenderness with fever, raised inflammatory markers and a change in bowel habit. CT confirms the diagnosis and shows complications such as abscess.
答案: A · 上腔静脉阻塞
肿瘤可压迫或侵犯上腔静脉,引起面部和手臂肿胀、胸壁静脉扩张、头痛和呼吸困难。应让患者坐起并紧急评估;治疗包括类固醇、支架置入以及放疗或化疗。
答案: C · Her antibodies cross the placenta and protect the newborn
Maternal pertussis antibodies cross the placenta and protect the newborn before it can be immunised. Whooping cough can be fatal in young infants.
答案: D · 今天来院评估胎心率
胎动减少可能是胎儿窘迫的警示。应尽快评估,通常在当天,检查胎心率并根据需要做进一步检查。接近足月时胎动通常不会减少。
答案: C · A bulging fontanelle, a high-pitched cry, poor feeding and irritability
Young infants with meningitis may have non-specific signs: fever or low temperature, poor feeding, lethargy or irritability, a high-pitched cry and a bulging fontanelle. Neck stiffness is often absent at this age.
答案: B · 开始飞沫隔离,并紧急请医生会诊,以免延误抗生素治疗
发热伴压之不褪色的皮疹提示脑膜炎球菌败血症。不得延误抗生素,在孩子接受有效抗生素约 24 小时之前应采取飞沫隔离。
答案: B · In factitious disorder, the aim is to be seen as ill; in malingering, the aim is an external reward
In both, symptoms are produced or exaggerated on purpose. In factitious disorder the motivation is internal, the sick role; in malingering it is external, such as money, drugs or avoiding duties.
答案: A · His usual methadone should continue, and additional analgesia is usually needed for acute pain
Maintenance methadone prevents withdrawal but does not treat acute pain. Patients with opioid tolerance often need more analgesia than usual. Withholding pain relief is unsafe and unethical.
答案: h = 66.5 in
家用计量和体重:护理考试使用取整的等量关系:1 茶匙(tsp)= 5 mL,1 汤匙(tbsp)= 15 mL = 3 tsp,1 液量盎司(fl oz)= 30 mL = 2 tbsp,1 杯 = 8 fl oz = 240 mL。体重方面,1 kg = 2.2 lb,1 lb = 16 oz;长度方面,1 英寸 = 2.54 cm。设置换算时,要让你不需要的单位相互约去。
答案: t = 12.92 h
24 小时制:下午 1 点起,小时数加 12(下午 3:45 = 15:45)。午夜到凌晨 12:59 为 00:00–00:59,中午 12:00–12:59 仍为 12:00–12:59。反过来换算时,13–23 点减 12 并标为下午;00 点变为凌晨 12 点。跨午夜计算时间要分两段:先算到 24:00(00:00),再从 00:00 算起。
答案: V = 10 mL
Solution strengths: a percentage strength is grams per 100 mL, so 1% = 1 g/100 mL = 10 mg/mL. A ratio strength 1:1000 means 1 g in 1000 mL = 1 mg/mL; 1:10 000 is 0.1 mg/mL. For a dilution the amount of drug stays the same: C₁·V₁ = C₂·V₂.
美国的标签现在标示 mg/mL(1 mg/mL = 1:1000;0.1 mg/mL = 1:10 000)。切勿静脉推注 1 mg/mL 的肾上腺素。
答案: V = 3.5 mL
剂量计算:给药量等于医嘱剂量除以现有药物的规格,再乘以该规格对应的量:给药量 = (医嘱剂量/储备规格) × 储备体积。始终统一单位(先把 g 换成 mg,mg 换成 mcg),并检查答案是否合理。
答案: R = 10 gtt/min
Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.
答案: D = 66.67 mcg/min
Dose-based infusions: concentration = amount of drug in the bag/bag volume. Pump rate (mL/h) = dose per hour/concentration, and dose per hour = mL/h × concentration. Convert per-minute doses to per-hour (× 60) and keep the mass units the same (1 g = 1000 mg, 1 mg = 1000 mcg).
答案: I = 1560 mL
出入量:入量计入所有进入体内的液体(口服液体、静脉输液、静脉用药及冲管液、管饲);冰屑按其体积的一半计。出量计入尿液、引流液、呕吐物和其他丢失。平衡 = 总入量 − 总出量;平衡为负表示净丢失。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: t = 3.3 h
输液时间:时间 (h) = 待输体积 (mL)/速率 (mL/h);使用袋中剩余的体积,而不是袋的容量。已输入体积 = 速率 × 时间。把小数小时换算为小时和分钟时,用小数部分 × 60(0.5 h = 30 min,而不是 50 min)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
约为 3 h 20 min,所以袋子大约在 10:50 输完。
答案: SI = 0.57
血压数值:脉压 PP = SBP − DBP。平均动脉压 MAP ≈ (SBP + 2·DBP)/3 = DBP + PP/3,这是基于正常心率下心脏每搏约有三分之二时间处于舒张期的估算(心率快时准确性下降);MAP 至少约 65 mmHg 是常用的器官灌注目标。休克指数 SI = 心率/SBP,正常约为 0.5–0.7;高于约 1 是休克的警示信号。
在通常的 0.5–0.7 之内或之下。
答案: DBP = 55 mmHg
血压数值:脉压 PP = SBP − DBP。平均动脉压 MAP ≈ (SBP + 2·DBP)/3 = DBP + PP/3,这是基于正常心率下心脏每搏约有三分之二时间处于舒张期的估算(心率快时准确性下降);MAP 至少约 65 mmHg 是常用的器官灌注目标。休克指数 SI = 心率/SBP,正常约为 0.5–0.7;高于约 1 是休克的警示信号。
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