感染控制与患者安全
方法
- 对每位患者都从标准预防开始:手卫生、针对预期暴露的个人防护装备、安全使用锐器。
- 按传播途径追加预防措施:接触传播(隔离衣、手套)、飞沫传播(外科口罩)、空气传播(N95、负压病房)。
- 保持无菌物品的无菌状态:如有疑问就视为不无菌;更换,绝不擦拭。
- 预防环境中的伤害:防跌倒措施,约束仅作为最后手段,火灾时用 RACE 和 PASS。
- 核对给药的正确原则、两个身份识别信息,以及对高警示药物的额外保障;报告差错和险兆事件。
公式表、每个专题的关键方法步骤和 40 道练习题,完整解答附在最后。
A nurse posts about an "interesting patient" on social media without naming them. Why is this a problem?
A stable patient is woken every hour for observations and is becoming tired and confused. What is the best nursing action?
A patient has a very low platelet count. Which safety measure is appropriate?
A patient restrained because of violent behavior is now calm, oriented and following instructions. What should the nurse do?
A parent calls to say their toddler has just swallowed drain cleaner. What should the nurse advise?
护士应首先处理护理助理的哪项报告?
一个新做的结肠造口在术后第二天呈暗紫色至黑色。这表示什么?
A nurse is teaching a patient who is starting warfarin. Which statement shows a need for further teaching?
A patient on warfarin for atrial fibrillation has a target INR of 2.0–3.0. How does the usual target for a patient with a mechanical mitral valve compare?
A patient with right upper abdominal pain from gallstones now has jaundice, a total bilirubin of 4.8 mg/dL (82 µmol/L) and a raised ALP. What is the most likely cause?
A patient with heart failure starts furosemide. Which self-monitoring instruction is most useful?
Carboprost is a prostaglandin used for postpartum haemorrhage. In which woman should it be avoided?
一名患者心房颤动已超过 48 小时,并已安排择期电复律。为什么事先需要抗凝?
A patient has new chest pain at rest. The ECG shows ST depression, but serial troponins remain normal. Which diagnosis fits best?
A patient with migraine takes painkillers or triptans on most days and now has a headache almost every day. What is the likely problem?
On the first day after a kidney transplant, urine output suddenly falls from 200 mL/h to 10 mL/h. What should the nurse check first?
严重急性胰腺炎时可能出现哪种电解质问题?
A patient with a toe ulcer says the leg pain is worse at night and eases when they hang the leg over the side of the bed. What does this suggest?
A woman with epilepsy is planning a pregnancy. Which advice is most appropriate?
A woman who had a placenta praevia and two previous caesareans is scheduled for a caesarean. The team plans for possible hysterectomy and blood products. Why?
A child with ITP has a low platelet count. Which advice is correct?
A child with sickle cell disease has been exposed to parvovirus B19 (fifth disease). Why is this a concern?
According to DSM-5, how long must signs of the disturbance last before schizophrenia can be diagnosed?
On the day after hip surgery, a 58-year-old patient has a new tremor, sweating, anxiety and a fast pulse. He did not report any alcohol use on admission. What should the nurse do?
练习题(虚构数值,不作为临床指导)。 一个剂量记录在 10:05 AM。哪个条目是 24 小时制中的同一时间?点击它。
练习题(虚构数值,不作为临床指导)。 一次输注从 17:55 开始,到次日早晨 06:05 结束(24 小时制)。它运行了多少分钟t?
某患者体重 45 kg。医嘱剂量为每天 7.5 mg/kg,分 2 次等量给药。每次给多少毫克 D?
一名患者身高 135 cm,体重 48 kg。医嘱为 175 mg/m²。用 Mosteller 公式 BSA = √(身高 (cm) × 体重 (kg)/3600) 求剂量 D,以 mg 表示。
滴注以 100 gtt/min 的速度通过滴系数为 60 gtt/mL 的输液器。患者在 12 小时内接受多少毫升 V?
一袋液体在 250 mL 中含药 200 mg,以 10 mL/h 的速度输注。患者每小时获得多少毫克 D?
练习题(虚构数值,不作为临床指导)。 一份含 50 单位普通胰岛素、容量 50 mL 的输液以 10 mL/h 输注。患者每小时接受多少单位 D?
练习题(虚构数值,不作为临床指导)。 一袋中含dopamine 400 mg,容量 250 mL。医嘱为 15 mcg/kg/min,患者体重 76 kg。输液泵速率 R 应设为多少 mL/h? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 记录显示了一名患者在一个 12 小时班次中的出入量。静脉输液在整个班次中按所示速率输注。求液体平衡 B = 入量 − 出量,以 mL 计(答案为负表示净丢失)。
练习题(虚构数值,不作为临床指导)。 一袋 1000 mL 的液体用输液泵以 75 mL/h 输注。到 19:00 时已输入 100 mL。还要多少小时 t 袋子才会输完? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 对这些观察结果使用 NEWS2 图表(SpO₂ 量表 1):呼吸频率 10 次/分,SpO₂ 96%吸室内空气,血压 136/82 mmHg,脉搏 104 次/分,清醒,体温 37.0 °C。NEWS2 总分是多少?
练习题(虚构数值,不作为临床指导)。 用 Braden 量表评估一位练习患者:感觉知觉: 无损害; 潮湿程度: 偶尔潮湿; 活动: 经常步行; 活动能力: 不受限制; 营养: 可能不足; 摩擦力和剪切力: 潜在问题。使用的分级为:19–23 无风险,15–18 轻度,13–14 中度,10–12 高,9 或以下极高。点击风险等级。
某练习血气显示 PaCO₂ 56 mmHg (7.5 kPa)。利用规则:在急性呼吸性酸中毒中,PaCO₂ 每比 40 高出 10 mmHg,HCO₃⁻ 升高 1 mmol/L,以HCO₃⁻ 24 mmol/L 为起点,求预期HCO₃⁻。
某练习血气显示呼吸性酸中毒:pH 7.30,PaCO₂ 78 mmHg (10.4 kPa),HCO₃⁻ 37 mmol/L。利用规则“HCO₃⁻ 每 10 mmHg 升高 1 mmol/L(急性)或 3.5 mmol/L(慢性)”进行分类。点选你的答案。
解读这条 II 导联心律条带。这是什么节律?点击你的答案。
这条 II 导联心电图显示心房与心室之间存在传导问题。这是什么节律?点击你的答案。
答案: D · The patient may still be identifiable, which breaches confidentiality
Details such as the ward, the condition or the date can reveal who a patient is. Professional codes forbid sharing patient information on social media, even without names.
答案: D · Ask the team whether the observations can safely be done less often
Lack of sleep can contribute to delirium. If the patient's scores are stable, the frequency of observations can be reviewed by the team so care is safe but less disruptive.
答案: B · Use a soft toothbrush and an electric razor
With thrombocytopenia, minor trauma can cause serious bleeding. Bleeding precautions include soft toothbrushes, electric razors, avoiding rectal procedures and IM injections where possible, and preventing falls.
答案: D · Remove the restraints, because the reason for them has ended
Restraints are used only as long as needed to keep people safe. Once the patient no longer presents a danger, the restraints are removed, even if the order has not yet expired.
答案: D · Do not make the child vomit; call poison control or emergency services now
Inducing vomiting after a corrosive is swallowed causes more burns to the throat and risks aspiration. The parent should get expert advice and emergency help at once.
答案: A · 今天上午腰椎融合术后,双腿没有感觉也不能活动
脊柱手术后双腿新出现无感觉和不能活动,可能意味着血肿压迫脊髓或神经,需要立即评估和上报。肺炎的黄色痰和长期的神经病变是预期的。
答案: A · 造口可能缺血,需要紧急评估
造口颜色暗淡或发黑提示血供不足、可能坏死,必须立即报告外科团队。
答案: A · "I can take aspirin if I get a headache."
Aspirin and other NSAIDs increase the bleeding risk with warfarin, so patients should ask before taking any new medicine. Paracetamol (acetaminophen) is usually the safer choice for simple pain.
答案: D · Higher, about 2.5–3.5
Mechanical heart valves, especially in the mitral position, have a high risk of thrombosis, so the INR target is usually higher, about 2.5–3.5. An INR of 5 or more carries a high bleeding risk.核对依据: Label: WARFARIN SODIUM tablet · DailyMed (NLM/FDA) (2012)
答案: D · A stone blocking the common bile duct
A gallstone in the common bile duct (choledocholithiasis) obstructs bile flow, raising conjugated bilirubin and ALP. Fever with jaundice and pain suggests cholangitis, an emergency. Simple cholecystitis usually causes only mild liver test changes.核对依据: Choledocholithiasis · MedlinePlus (NIH) (2025); Cholangitis · MedlinePlus (NIH) (2026)
答案: A · Weigh daily at the same time on the same scales
Daily weight is the best home measure of fluid balance. A rapid gain suggests fluid retention, and a rapid loss suggests overdiuresis and dehydration, both of which should be reported.
答案: B · A woman with asthma
Carboprost is a PGF2-alpha analogue that can cause bronchospasm. Oxytocin is first-line, and carboprost is avoided in asthma.
答案: A · 恢复窦性心律时,心房内的血栓可能脱落
心房颤动超过 48 小时后,心房内可能存在血栓。恢复有序收缩可将其排出而引起卒中。患者通常在复律前至少抗凝三周(或经食管超声排除血栓),复律后至少抗凝四周。
答案: A · Unstable angina
Unstable angina is new, worsening or rest angina without a troponin rise. It is an acute coronary syndrome and is managed urgently because it can progress to infarction. Stable angina is predictable and exertional. NSTEMI has a rising troponin.
答案: A · Medication overuse headache
Frequent use of painkillers or triptans can cause medication overuse headache. Treatment involves withdrawing the overused drug under guidance and starting a preventive treatment if needed.
答案: C · That the catheter is not blocked or kinked
A sudden drop in output after transplant may be caused by a blocked catheter, often from clots. The nurse checks the tubing and may flush the catheter per protocol, and then escalates urgently, because vascular thrombosis or rejection are also possible.
答案: A · 低钙血症
脂肪坏死释放脂肪酸,与钙结合(皂化),使血清钙降低。低钙血症是严重程度的标志,可引起手足抽搐和心律失常。而高钙血症则可能是胰腺炎的病因。
答案: D · Arterial insufficiency
Rest pain eased by dependency is typical of severe peripheral arterial disease. Elevating the leg worsens pain, and compression is avoided. Vascular assessment is needed.
答案: C · Review her medicines with her doctor before conception
Preconception review allows a switch to the lowest-risk effective drug, often at the lowest effective dose, and higher-dose folic acid. Most women can breastfeed while taking antiepileptics.
答案: C · She is at high risk of placenta accreta spectrum
A placenta praevia overlying a previous caesarean scar greatly raises the risk of an abnormally adherent placenta. This can cause massive haemorrhage, so delivery is planned in a unit with blood bank support.
答案: D · Avoid contact sports and medicines such as ibuprofen and aspirin
While platelets are low, the child should avoid contact sports and activities with a high risk of head injury, and avoid NSAIDs and aspirin, which impair platelet function. A soft toothbrush is used, and parents report any heavy bleeding.
答案: C · It can stop red cell production for days and cause severe anaemia
Parvovirus B19 temporarily stops red cell production. Healthy children barely notice this, but in sickle cell disease red cells survive only a short time, so an aplastic crisis with severe anaemia can develop and may need transfusion.
答案: C · At least 6 months, including at least 1 month of active symptoms
Schizophrenia needs continuous signs for at least 6 months, with at least 1 month of active-phase symptoms such as delusions or hallucinations. An episode of 1 to 6 months is schizophreniform disorder.
答案: C · Ask him and his family about his alcohol use and the time of his last drink, and report the findings
Unexpected alcohol withdrawal is common in surgical patients. Asking about drinking, using a withdrawal scale and reporting early allows treatment before seizures or delirium tremens develop.
答案: 10:05
24 小时制:下午 1 点起,小时数加 12(下午 3:45 = 15:45)。午夜到凌晨 12:59 为 00:00–00:59,中午 12:00–12:59 仍为 12:00–12:59。反过来换算时,13–23 点减 12 并标为下午;00 点变为凌晨 12 点。跨午夜计算时间要分两段:先算到 24:00(00:00),再从 00:00 算起。
答案: t = 730 min
24 小时制:下午 1 点起,小时数加 12(下午 3:45 = 15:45)。午夜到凌晨 12:59 为 00:00–00:59,中午 12:00–12:59 仍为 12:00–12:59。反过来换算时,13–23 点减 12 并标为下午;00 点变为凌晨 12 点。跨午夜计算时间要分两段:先算到 24:00(00:00),再从 00:00 算起。
答案: D = 168.8 mg
剂量计算:给药量等于医嘱剂量除以现有药物的规格,再乘以该规格对应的量:给药量 = (医嘱剂量/储备规格) × 储备体积。始终统一单位(先把 g 换成 mg,mg 换成 mcg),并检查答案是否合理。
答案: D = 234.8 mg
Body-surface-area dosing: many cytotoxic and some paediatric doses are prescribed per square metre of body surface area: dose (mg) = dose per m² × BSA (m²). The Mosteller formula estimates BSA = √(height (cm) × weight (kg)/3600).
答案: V = 1200 mL
Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.
答案: D = 8 mg/h
输注速率:输液泵按 mL/h = 体积/时间(小时)设定。重力滴注按每分钟滴数计:gtt/min = 体积 (mL) × 滴系数 (gtt/mL)/时间 (min)。 滴系数印在输液器包装上:普通输液器为 10、15 或 20 gtt/mL(输血器在美国常为 10 gtt/mL,在英国为 15),微量输液器为 60 gtt/mL。务必使用题目或包装给出的滴系数。
答案: D = 10 件/h
肝素和胰岛素输注:浓度 = 袋中单位数/袋容量 (units/mL)。泵速 (mL/h) = 每小时单位数/浓度,每小时单位数 = mL/h × 浓度。按体重给药时,先求 units/h = units/kg/h × 体重。推注体积 = 所需单位数/药瓶规格。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: R = 42.8 mL/h
滴定输注:先求以 mcg/mL 计的浓度(mg × 1000/mL)。按体重给药时,mcg/min = mcg/kg/min × 体重。然后 mL/h = mcg/min × 60/浓度。反推时,mcg/kg/min = mL/h × 浓度/(60 × 体重)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: B = 1265 mL
出入量:入量计入所有进入体内的液体(口服液体、静脉输液、静脉用药及冲管液、管饲);冰屑按其体积的一半计。出量计入尿液、引流液、呕吐物和其他丢失。平衡 = 总入量 − 总出量;平衡为负表示净丢失。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
为正:摄入的液体多于排出的液体。
答案: t = 12 h
输液时间:时间 (h) = 待输体积 (mL)/速率 (mL/h);使用袋中剩余的体积,而不是袋的容量。已输入体积 = 速率 × 时间。把小数小时换算为小时和分钟时,用小数部分 × 60(0.5 h = 30 min,而不是 50 min)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
约为 12 h 00 min,所以袋子大约在 07:00 输完。
答案: NEWS2 = 2
NEWS2(国家早期预警评分 2,英国皇家内科医师学会 2017):按图表为七个参数分别评分(呼吸频率、量表 1 的 SpO₂、吸空气还是吸氧、收缩压、脉搏、按 ACVPU 量表评定的意识状态和体温),然后把分数相加。临床风险:0–4 为低;任何单项参数得 3 分为中低;5–6 为中;7 或以上为高。总分 5 或以上需要紧急响应。
答案: 无风险
Braden 量表:评估压力性损伤风险的六个分项。感觉知觉、潮湿程度、活动、活动能力和营养各评 1 至 4 分,从最差水平(1)到无问题(4);摩擦力和剪切力评 1 至 3 分。总分为 6 至 23,总分越低风险越高。常用分级:19–23 无风险,15–18 轻度风险,13–14 中度风险,10–12 高风险,9 分及以下为极高风险。
答案: HCO₃⁻ = 25.6 mmol/L
预期代偿:代谢性酸中毒时,温特公式预测 PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg;实测值高于该范围提示合并呼吸性酸中毒,低于该范围提示合并呼吸性碱中毒。阴离子间隙 AG = Na⁺ − (Cl⁻ + HCO₃⁻),正常约为 8–12 mmol/L,用于区分高阴离子间隙与正常阴离子间隙代谢性酸中毒;低白蛋白会掩盖升高的间隙(白蛋白低于 4.0 的部分,每 g/dL 加 2.5)。Δ 比值 (AG − 12)/(24 − HCO₃⁻) 约在 0.8 到 2 之间符合单纯高间隙酸中毒(有些教材用 1 代替 0.8),低于此范围提示合并正常间隙酸中毒,高于 2 提示合并代谢性碱中毒。
答案: 慢性
预期代偿:代谢性酸中毒时,温特公式预测 PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg;实测值高于该范围提示合并呼吸性酸中毒,低于该范围提示合并呼吸性碱中毒。阴离子间隙 AG = Na⁺ − (Cl⁻ + HCO₃⁻),正常约为 8–12 mmol/L,用于区分高阴离子间隙与正常阴离子间隙代谢性酸中毒;低白蛋白会掩盖升高的间隙(白蛋白低于 4.0 的部分,每 g/dL 加 2.5)。Δ 比值 (AG − 12)/(24 − HCO₃⁻) 约在 0.8 到 2 之间符合单纯高间隙酸中毒(有些教材用 1 代替 0.8),低于此范围提示合并正常间隙酸中毒,高于 2 提示合并代谢性碱中毒。
答案: 一度房室传导阻滞
节律标准(II 导联):窦性心律每个 QRS 之前都有直立的 P 波,PR 恒定为 0.12–0.20 s,QRS 狭窄:60–100 次/分为正常窦性心律,低于 60 为窦性心动过缓,高于 100 为窦性心动过速。心房颤动:无 P 波,基线呈颤动,R–R 绝对不规则。心房扑动:约 250–350 次/分的锯齿状扑动波,伴固定的传导比例,如 2:1 或 4:1。一度房室传导阻滞:窦性心律,PR 恒定且大于 0.20 s。交界性心律:窄 QRS,40–60 次/分,P 波缺失或倒置(PR 低于 0.12 s,或 P 波在 QRS 之后)。室性早搏(PVC)是提前出现的宽大(0.12 s 或以上)、形态怪异的 QRS,没有 P 波,T 波方向相反,通常有完全性代偿间歇;二联律是指每隔一个搏动就有一个室性早搏。
答案: 二度 I 型房室传导阻滞(文氏现象)
房室传导阻滞:逐个标出 P 波,检查哪些 P 波后面跟着 QRS。一度:每个 P 波都下传,PR 恒定且大于 0.20 s。二度 I 型(Mobitz I,文氏现象):PR 逐搏延长,直到一个 P 波未下传,然后周期重新开始(成组搏动)。二度 II 型(Mobitz II):下传搏动的 PR 保持恒定,P 波突然不下传;QRS 常增宽。三度(完全性)阻滞:P 波和 QRS 波群各自规则但互相独立,PR 随机变化,心房率快于逸搏率(交界性逸搏 40–60 次/分,QRS 窄;室性逸搏 20–40 次/分,QRS 宽)。2:1 阻滞仅凭一份条带无法判断是 I 型还是 II 型。
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