感染控制与患者安全
方法
- 对每位患者都从标准预防开始:手卫生、针对预期暴露的个人防护装备、安全使用锐器。
- 按传播途径追加预防措施:接触传播(隔离衣、手套)、飞沫传播(外科口罩)、空气传播(N95、负压病房)。
- 保持无菌物品的无菌状态:如有疑问就视为不无菌;更换,绝不擦拭。
- 预防环境中的伤害:防跌倒措施,约束仅作为最后手段,火灾时用 RACE 和 PASS。
- 核对给药的正确原则、两个身份识别信息,以及对高警示药物的额外保障;报告差错和险兆事件。
公式表、每个专题的关键方法步骤和 40 道练习题,完整解答附在最后。
A dying patient asks to see a chaplain or religious leader. What should the nurse do?
Which pair of details is best for confirming a patient's identity before giving a medicine?
下列哪种使用药瓶和注射器的做法是安全的?
一名患者伤口曾感染 MRSA,现在需要换药。哪种个人防护装备是恰当的?
A patient with heart failure gained 2 kg (about 4 lb) since yesterday and is more breathless when lying down. What should the nurse do first?
A patient has a potassium of 7.0 mEq/L with peaked T waves. Several drugs are prescribed. Which one is usually given first to protect the heart?
Which adverse effects should be monitored for in a patient receiving IV gentamicin?
一名老年患者夜间突然出现意识混乱,注意力时好时坏。首先应寻找什么原因?
一名服用地高辛的患者血药水平为 2.8 ng/mL,心率 52 次/分。护士最好的措施是什么?
The nurse teaches a patient who is collecting a 24-hour urine sample at home. Which statement shows a need for further teaching?
What should the nurse teach a patient about taking levothyroxine?
A patient on methadone is also prescribed diazepam for anxiety. What is the main safety concern?
Why is a non-selective beta-blocker such as propranolol usually avoided in a patient with asthma?
A woman starting rifampicin (rifampin) for tuberculosis uses a combined oral contraceptive pill. What advice is correct?
A patient has taken metformin for many years and now has tingling feet and a low haemoglobin. Which blood test is most relevant?
对使用甘露醇治疗颅内压升高的患者,哪项护理很重要?
Why is the Lund and Browder chart preferred to the rule of nines for children?
A patient is booked for a urea breath test for H. pylori. Which medicine should usually be stopped 2 weeks before the test?
On day 1 after birth, a woman's white cell count is mildly raised and she has no symptoms. How should this be interpreted?
A woman had a classical (vertical upper-segment) caesarean in her last pregnancy. She asks about her plan for this birth. Which answer is accurate?
钳捏抓握(用拇指和食指捏起小物体)通常在大约多大时发育出来?
A child with a central venous catheter for chemotherapy develops fever and rigors shortly after the line is flushed. What should the nurse suspect?
When is the best time to teach a patient with an anxiety disorder a relaxation technique?
On the day after hip surgery, a 58-year-old patient has a new tremor, sweating, anxiety and a fast pulse. He did not report any alcohol use on admission. What should the nurse do?
练习题(虚构数值,不作为临床指导)。 一个剂量记录在 01:45(24 小时制)。哪个条目是 12 小时制中的同一时间?点击它。
练习题(虚构数值,不作为临床指导)。 一张处方写着口服混悬液½ tbsp,每天两次,共 7 天。按1 tbsp = 15 mL,整个疗程需要多少 mLV?
一支肾上腺素安瓿标示为 1:1000(1 mg/mL)。医嘱为 0.5 mg 肌内注射(IM),用于严重过敏反应。你应抽取多少体积 V?
一名体重 28 kg 的儿童,医嘱为口服混悬液每次 12.5 mg/kg,该混悬液每 5 mL 含 250 mg。你应给多少体积 V?
用滴系数为 20 滴/mL 的输液器在 10 小时内输入 1500 mL。求滴速 R(滴/分)。
一组输液以 40 滴/分的速度经 60 滴/mL 的输液器滴注。袋中还剩 400 mL。还需多少小时 t 才会滴完?
练习题(虚构数值,不作为临床指导)。 一份输液含普通胰岛素 250 单位,容量 250 mL。医嘱为 1.5 units/h。求泵速 R,以 mL/h 计。 保留一位小数。
练习题(虚构数值,不作为临床指导)。 一袋中含dopamine 800 mg,容量 500 mL。医嘱为 5 mcg/kg/min,患者体重 88 kg。输液泵速率 R 应设为多少 mL/h? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 记录显示了一名患者在一个 12 小时班次中的出入量。静脉输液在整个班次中按所示速率输注。求液体平衡 B = 入量 − 出量,以 mL 计(答案为负表示净丢失)。
练习题(虚构数值,不作为临床指导)。 一袋 500 mL 的液体用输液泵以 100 mL/h 输注。到 18:30 时已输入 300 mL。还要多少小时 t 袋子才会输完? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 用 Morse 跌倒评分评估一位练习患者:过去 3 个月内的跌倒史: 是; 次要诊断: 是; 行走辅助: 拐杖、手杖或助行器; 静脉输液或封管: 否; 步态: 虚弱; 精神状态: 了解自身局限。求 Morse 总分MFS。
练习题(虚构数值,不作为临床指导)。 用 Braden 量表评估一位练习患者:感觉知觉: 轻度受限; 潮湿程度: 很少潮湿; 活动: 偶尔步行; 活动能力: 非常受限; 营养: 非常差; 摩擦力和剪切力: 无明显问题。使用的分级为:19–23 无风险,15–18 轻度,13–14 中度,10–12 高,9 或以下极高。点击风险等级。
某练习血气显示代谢性酸中毒,HCO₃⁻ 8 mmol/L。用温特公式求预期PaCO₂(范围的中心),单位 mmHg。
某练习血气显示呼吸性酸中毒:pH 7.25,PaCO₂ 76 mmHg (10.1 kPa),HCO₃⁻ 32 mmol/L。利用规则“HCO₃⁻ 每 10 mmHg 升高 1 mmol/L(急性)或 3.5 mmol/L(慢性)”进行分类。点选你的答案。
解读这条 II 导联心律条带。这是什么节律?点击你的答案。
识别这条 II 导联心电图上的节律。点击你的答案。
答案: D · Arrange the visit as soon as possible
Spiritual care is an important part of end-of-life care. The nurse responds promptly to such requests and records the patient's wishes.
答案: C · Full name and date of birth, checked against the wristband
At least two personal identifiers, such as name, date of birth and hospital number, are checked with the patient and the wristband. Bed and room numbers change and are not identifiers.
答案: A · 每次穿刺药瓶时都使用新的无菌针头和注射器
针头和注射器均为一次性使用。用过的注射器会污染药瓶,肝炎暴发就曾与注射器重复使用有关。单剂量药瓶只用于一名患者,多剂量药瓶尽可能专用于一名患者。
答案: C · 隔离衣和手套,若可能有飞溅则加戴护目装备和口罩
MRSA 通过接触传播,因此应穿隔离衣、戴手套。标准预防要求在可能有伤口渗液飞溅时加用眼部和面部防护。伤口 MRSA 不需要呼吸器。
答案: A · Assess the lungs, oxygen saturation and swelling, then inform the provider
A rapid weight gain with orthopnea suggests fluid overload and worsening heart failure. The nurse assesses breathing and fluid status and informs the provider, who may adjust the diuretic.
答案: D · IV calcium gluconate
IV calcium stabilizes the cardiac cell membranes within minutes and is given first when hyperkalemia changes the ECG. Insulin with glucose, binders and diuretics then lower the potassium.
答案: A · Kidney damage and hearing loss
Gentamicin is nephrotoxic and ototoxic. Blood levels and renal function are monitored, and any tinnitus, dizziness or hearing change is reported.
答案: B · 由感染或药物等潜在问题引起的谵妄
谵妄在数小时到数天内发生,并呈波动性。常见原因有感染、药物、脱水、疼痛、便秘和尿潴留。痴呆则是缓慢发展的。
答案: D · 暂停该剂量并通知开医嘱者
2.8 ng/mL 的水平高于通常范围,心率慢也符合中毒。护士应暂停该剂量,检查钾和心电图并通知开医嘱者。
答案: C · "If I forget to save one void, I'll just carry on to the end"
A 24-hour collection is valid only if every void in the period is saved; if a void is lost, the nurse or clinic is told and the collection is usually restarted. Keeping the container cool as instructed, adding the final void at the end time and asking about restrictions are correct.核对依据: Urine 24-hour volume · MedlinePlus (NIH) (2025)
答案: D · Take it on an empty stomach, 30–60 minutes before breakfast
Levothyroxine is best absorbed on an empty stomach, and calcium, iron and antacids should be taken some hours apart. It is taken every day, usually for life.
答案: B · Additive sedation and respiratory depression
Combining opioids with benzodiazepines greatly increases the risk of sedation, respiratory depression and death. If both are needed, the lowest doses are used and the patient is monitored closely.
答案: D · It can cause bronchospasm by blocking beta-2 receptors
Beta-2 receptors in the airways mediate bronchodilation. Blocking them can trigger severe bronchospasm in asthma and also blunts the effect of salbutamol. Cardioselective beta-1 blockers are safer but still used with caution.
答案: D · Use another reliable method, as rifampicin reduces the pill's effect
Rifampicin induces liver enzymes that break down oestrogen and progestogen, so hormonal contraception may fail. A non-hormonal or unaffected method, such as a copper IUD, is advised during and for a time after treatment. The interaction also affects warfarin and many other drugs.
答案: D · Vitamin B12 level
Long-term metformin can lower vitamin B12 absorption, causing anaemia and neuropathy that may be mistaken for diabetic neuropathy. B12 levels are checked, especially when symptoms appear.
答案: D · 密切监测尿量、血钠和渗透压
甘露醇把水从脑内拉入血液,并由肾脏排泄,引起大量利尿。需要监测脱水、低血压、电解质紊乱和高渗透压,通常需要留置导尿管。
答案: D · It adjusts for body proportions that change with age
The Lund and Browder chart gives different percentages for the head and legs at different ages, so it is more accurate in children and is also widely used in adults.
答案: A · Omeprazole
PPIs suppress H. pylori and can give false-negative breath or stool tests, so they are usually stopped 2 weeks before. Antibiotics are usually stopped 4 weeks before testing.
答案: D · It can be normal soon after birth
Leucocytosis is common in labour and the early postnatal period. It must be interpreted with clinical signs such as fever, pain and lochia changes rather than on its own.
答案: B · A planned repeat caesarean before labour is advised
A classical uterine scar carries a high risk of rupture during labour, so trial of labour is contraindicated. A repeat caesarean is planned before labour starts, and she should come in at once if contractions begin.
答案: D · 约 9 至 10 个月
钳捏抓握通常在约 9–10 个月时出现,到约 12 个月时变得灵巧精细。这也是这个年龄小物体成为窒息风险的原因。
答案: C · A catheter-related bloodstream infection
Fever and rigors linked to flushing or use of a central line strongly suggest line infection. Blood cultures are taken (often from the line and a peripheral vein) and IV antibiotics are started urgently, especially if the child is neutropenic.
答案: C · When the patient's anxiety is at a mild level
Patients with severe anxiety or panic cannot take in new information. New coping skills are taught when anxiety is low, so they can be used later when anxiety rises.
答案: C · Ask him and his family about his alcohol use and the time of his last drink, and report the findings
Unexpected alcohol withdrawal is common in surgical patients. Asking about drinking, using a withdrawal scale and reporting early allows treatment before seizures or delirium tremens develop.
答案: 1:45 AM
24 小时制:下午 1 点起,小时数加 12(下午 3:45 = 15:45)。午夜到凌晨 12:59 为 00:00–00:59,中午 12:00–12:59 仍为 12:00–12:59。反过来换算时,13–23 点减 12 并标为下午;00 点变为凌晨 12 点。跨午夜计算时间要分两段:先算到 24:00(00:00),再从 00:00 算起。
答案: V = 105 mL
量纲分析:先写出已知量,再乘以写成分数形式的换算系数(例如 60 min/1 h 或 1 mg/1000 mcg),使每个不需要的单位在分子和分母各出现一次并相互约去。只剩下所求单位时再计算。使用题目给出的等量关系,只对最终答案取整。
答案: V = 0.5 mL
Solution strengths: a percentage strength is grams per 100 mL, so 1% = 1 g/100 mL = 10 mg/mL. A ratio strength 1:1000 means 1 g in 1000 mL = 1 mg/mL; 1:10 000 is 0.1 mg/mL. For a dilution the amount of drug stays the same: C₁·V₁ = C₂·V₂.
美国的标签现在标示 mg/mL(1 mg/mL = 1:1000;0.1 mg/mL = 1:10 000)。切勿静脉推注 1 mg/mL 的肾上腺素。
答案: V = 7 mL
剂量计算:给药量等于医嘱剂量除以现有药物的规格,再乘以该规格对应的量:给药量 = (医嘱剂量/储备规格) × 储备体积。始终统一单位(先把 g 换成 mg,mg 换成 mcg),并检查答案是否合理。
答案: R = 50 gtt/min
输注速率:输液泵按 mL/h = 体积/时间(小时)设定。重力滴注按每分钟滴数计:gtt/min = 体积 (mL) × 滴系数 (gtt/mL)/时间 (min)。 滴系数印在输液器包装上:普通输液器为 10、15 或 20 gtt/mL(输血器在美国常为 10 gtt/mL,在英国为 15),微量输液器为 60 gtt/mL。务必使用题目或包装给出的滴系数。
答案: t = 10 h
输注速率:输液泵按 mL/h = 体积/时间(小时)设定。重力滴注按每分钟滴数计:gtt/min = 体积 (mL) × 滴系数 (gtt/mL)/时间 (min)。 滴系数印在输液器包装上:普通输液器为 10、15 或 20 gtt/mL(输血器在美国常为 10 gtt/mL,在英国为 15),微量输液器为 60 gtt/mL。务必使用题目或包装给出的滴系数。
答案: R = 1.5 mL/h
肝素和胰岛素输注:浓度 = 袋中单位数/袋容量 (units/mL)。泵速 (mL/h) = 每小时单位数/浓度,每小时单位数 = mL/h × 浓度。按体重给药时,先求 units/h = units/kg/h × 体重。推注体积 = 所需单位数/药瓶规格。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: R = 16.5 mL/h
滴定输注:先求以 mcg/mL 计的浓度(mg × 1000/mL)。按体重给药时,mcg/min = mcg/kg/min × 体重。然后 mL/h = mcg/min × 60/浓度。反推时,mcg/kg/min = mL/h × 浓度/(60 × 体重)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: B = 700 mL
出入量:入量计入所有进入体内的液体(口服液体、静脉输液、静脉用药及冲管液、管饲);冰屑按其体积的一半计。出量计入尿液、引流液、呕吐物和其他丢失。平衡 = 总入量 − 总出量;平衡为负表示净丢失。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
为正:摄入的液体多于排出的液体。
答案: t = 2 h
输液时间:时间 (h) = 待输体积 (mL)/速率 (mL/h);使用袋中剩余的体积,而不是袋的容量。已输入体积 = 速率 × 时间。把小数小时换算为小时和分钟时,用小数部分 × 60(0.5 h = 30 min,而不是 50 min)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
约为 2 h 00 min,所以袋子大约在 20:30 输完。
答案: MFS = 65
Morse 跌倒评分:六个条目。跌倒史:否 0 分,是 25 分。次要诊断:否 0 分,是 15 分。行走辅助:无、卧床休息或护士协助 0 分;拐杖、手杖或助行器 15 分;扶着家具 30 分。静脉输液或封管:否 0 分,是 20 分。步态:正常、卧床休息或轮椅 0 分;虚弱 10 分;受损 20 分。精神状态:了解自身局限 0 分;高估或忘记自身局限 15 分。总分为 0 至 125。各医院的风险分界值不同;常用的一套是 0–24 低风险,25–44 中度风险,45 及以上为高风险。
答案: 轻度风险
Braden 量表:评估压力性损伤风险的六个分项。感觉知觉、潮湿程度、活动、活动能力和营养各评 1 至 4 分,从最差水平(1)到无问题(4);摩擦力和剪切力评 1 至 3 分。总分为 6 至 23,总分越低风险越高。常用分级:19–23 无风险,15–18 轻度风险,13–14 中度风险,10–12 高风险,9 分及以下为极高风险。
答案: PaCO₂ = 20 mmHg
预期代偿:代谢性酸中毒时,温特公式预测 PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg;实测值高于该范围提示合并呼吸性酸中毒,低于该范围提示合并呼吸性碱中毒。阴离子间隙 AG = Na⁺ − (Cl⁻ + HCO₃⁻),正常约为 8–12 mmol/L,用于区分高阴离子间隙与正常阴离子间隙代谢性酸中毒;低白蛋白会掩盖升高的间隙(白蛋白低于 4.0 的部分,每 g/dL 加 2.5)。Δ 比值 (AG − 12)/(24 − HCO₃⁻) 约在 0.8 到 2 之间符合单纯高间隙酸中毒(有些教材用 1 代替 0.8),低于此范围提示合并正常间隙酸中毒,高于 2 提示合并代谢性碱中毒。
答案: 慢性基础上的急性
预期代偿:代谢性酸中毒时,温特公式预测 PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg;实测值高于该范围提示合并呼吸性酸中毒,低于该范围提示合并呼吸性碱中毒。阴离子间隙 AG = Na⁺ − (Cl⁻ + HCO₃⁻),正常约为 8–12 mmol/L,用于区分高阴离子间隙与正常阴离子间隙代谢性酸中毒;低白蛋白会掩盖升高的间隙(白蛋白低于 4.0 的部分,每 g/dL 加 2.5)。Δ 比值 (AG − 12)/(24 − HCO₃⁻) 约在 0.8 到 2 之间符合单纯高间隙酸中毒(有些教材用 1 代替 0.8),低于此范围提示合并正常间隙酸中毒,高于 2 提示合并代谢性碱中毒。
答案: 交界性心律
节律标准(II 导联):窦性心律每个 QRS 之前都有直立的 P 波,PR 恒定为 0.12–0.20 s,QRS 狭窄:60–100 次/分为正常窦性心律,低于 60 为窦性心动过缓,高于 100 为窦性心动过速。心房颤动:无 P 波,基线呈颤动,R–R 绝对不规则。心房扑动:约 250–350 次/分的锯齿状扑动波,伴固定的传导比例,如 2:1 或 4:1。一度房室传导阻滞:窦性心律,PR 恒定且大于 0.20 s。交界性心律:窄 QRS,40–60 次/分,P 波缺失或倒置(PR 低于 0.12 s,或 P 波在 QRS 之后)。室性早搏(PVC)是提前出现的宽大(0.12 s 或以上)、形态怪异的 QRS,没有 P 波,T 波方向相反,通常有完全性代偿间歇;二联律是指每隔一个搏动就有一个室性早搏。
答案: 心脏停搏
室性节律:室性心动过速是连续三个或以上宽大(0.12 s 或以上)的波群,频率超过 100 次/分,通常为 150–250 次/分,节律规则,没有相关的 P 波。心室颤动是紊乱、不规则的波形,无法辨认 P 波、QRS 波群或 T 波,也没有可计数的频率。心脏停搏是几乎平直的线,没有心室活动;平直线一定要通过检查患者、导联和增益并换一个导联来确认。在复苏指南中,室颤和无脉性室速是可电击心律,心脏停搏则不是。
平直线必须核实:查看患者、导联和增益,并换看第二个导联,因为电极脱落或细颤型室颤都可能看起来像心脏停搏。
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