感染控制与患者安全
方法
- 对每位患者都从标准预防开始:手卫生、针对预期暴露的个人防护装备、安全使用锐器。
- 按传播途径追加预防措施:接触传播(隔离衣、手套)、飞沫传播(外科口罩)、空气传播(N95、负压病房)。
- 保持无菌物品的无菌状态:如有疑问就视为不无菌;更换,绝不擦拭。
- 预防环境中的伤害:防跌倒措施,约束仅作为最后手段,火灾时用 RACE 和 PASS。
- 核对给药的正确原则、两个身份识别信息,以及对高警示药物的额外保障;报告差错和险兆事件。
公式表、每个专题的关键方法步骤和 40 道练习题,完整解答附在最后。
Why should insulin injection sites be rotated?
During tracheal suction a patient's SpO₂ falls from 95% to 85% and the heart rate drops. What should the nurse do?
What is the main aim of purposeful hourly rounding?
A visitor is receiving an electric shock from a faulty lamp and is still touching it. What should the nurse do first?
一名通常在产科工作的护士被调派到成人内科病房。最适合分配给这名护士的患者是哪一位?
Which patient with cirrhosis should the nurse see first?
给予 β 受体阻滞剂之前,最重要的是检查哪项观察指标?
A nurse notices that a wrong dose of a drug was prepared but was caught before it was given. What should be done?
在给予处方的静脉氯化钾之前,哪项评估最重要?
A patient on IV gentamicin has a trough level above the target, and the creatinine has risen since yesterday. The next dose is due. What is the best action?
Why is simvastatin traditionally taken in the evening?
Which heart failure drug improves symptoms and reduces hospital admissions but has not been shown to reduce mortality?
During an episode of chest pain, a patient's ECG shows new horizontal ST depression. What does this most likely indicate?
A patient who has had a total laryngectomy becomes breathless and needs oxygen. How should it be given?
A patient who has had type 1 diabetes for 30 years says they no longer feel the warning signs of a hypo. What is this called?
After removal of a cortisol-producing adrenal adenoma, why may the patient need hydrocortisone for months?
Which statement about fatigue during radiotherapy is correct?
A patient finds daily wound dressing changes very painful. What is the most effective nursing approach?
Why is a baby of a mother with poorly controlled diabetes often large?
A newborn's bilirubin is rising quickly at 30 hours despite phototherapy, and the baby is lethargic with an arched back and high-pitched cry. What does this suggest?
对疑似 Wilms 瘤(肾母细胞瘤)的儿童,适用哪项护理注意事项?
A child has a swollen, red eyelid with fever, pain on moving the eye and blurred vision. What should the nurse suspect?
一名精神分裂症患者说:“那些声音在说我是邪恶的。”哪种回应最好?
A patient asks the nurse to pray with her before her ECT. The nurse does not share her religion. What is the most appropriate response?
练习题(虚构数值,不作为临床指导)。 一次体重换算得到 4.7661 kg。 本练习的规则是:体重取到最接近的十分之一千克。你记录的数值x是多少?
练习题(虚构数值,不作为临床指导)。 一次输注的给药速率为 6 mg/h。请把这个剂量速率D用 mcg/min 表示。取到一位小数。
一名体重 8 kg 的儿童按 10 mg/kg 处方用药。原液浓度为 50 mg/mL。请抽取剂量:应给多少体积 V?
一袋输液在 1000 mL 中含 40000 单位药物。医嘱为每小时 1000 单位。泵速 R 应设为多少 mL/h?
用滴系数为 10 滴/mL 的输液器在 10 小时内输入 1000 mL。求滴速 R(滴/分)。 取整到最接近的整数。
将 100 mg 药物稀释于 100 mL 中,通过滴系数为 15 gtt/mL 的输液器重力滴注。医嘱为每小时 20 mg。求滴速 R,以每分钟滴数表示。
练习题(虚构数值,不作为临床指导)。 一份输液含普通胰岛素 250 单位,容量 250 mL。医嘱为 1.5 units/h。求泵速 R,以 mL/h 计。 保留一位小数。
练习题(虚构数值,不作为临床指导)。 一名体重 65 kg 的患者的医嘱为norepinephrine 8 mcg/min。输液袋中含 4 mg,容量 250 mL。求泵速 R,以 mL/h 计。 保留一位小数。
练习题(虚构数值,不作为临床指导)。 记录显示了一名患者在一个 8 小时班次中的出入量。静脉输液在整个班次中按所示速率输注。求总入量 I,以 mL 计。 冰屑按其体积的一半计。
练习题(虚构数值,不作为临床指导)。 一份 500 mL 的输液于 07:30 开始以 100 mL/h 输注。4 小时后速率改为 80 mL/h,之后不再改变。从开始算起多少小时 t 后袋子会输完? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 对这些观察结果使用 NEWS2 图表(SpO₂ 量表 1):呼吸频率 30 次/分,SpO₂ 99%吸室内空气,血压 118/70 mmHg,脉搏 58 次/分,清醒,体温 38.1 °C。NEWS2 总分是多少?
练习题(虚构数值,不作为临床指导)。 出生后 5 分钟,一名练习用新生儿的表现为:躯干粉红,手脚青紫,心率 80 次/分,刺激时做鬼脸,活动活跃,呼吸缓慢、不规则,哭声微弱。 为 Apgar 评分并点击该评分的解读。
练习数值:Na⁺ 142 mmol/L,葡萄糖 16.2 mmol/L,尿素 23 mmol/L。计算血清渗透压 Osm = 2·Na⁺ + 葡萄糖 + 尿素,取最接近的整数。
练习数值:Na⁺ 134,Cl⁻ 108,HCO₃⁻ 17 mmol/L,白蛋白 38 g/L。求经白蛋白校正的阴离子间隙 AGc = AG + 0.25·(40 − 白蛋白)。
这条 II 导联心电图显示心房扑动。测量扑动波间期,求出心房率(单位:次/分)。
识别这条 II 导联心电图上的节律。点击你的答案。
答案: C · To prevent lumpy fatty swelling that affects absorption
Injecting in the same place causes lipohypertrophy, which makes absorption unpredictable. Patients rotate within an area and check sites for lumps.
答案: D · Stop suctioning and give oxygen until the patient recovers
Suction removes oxygen and can stimulate the vagus nerve, causing hypoxia and bradycardia. The nurse stops, oxygenates and lets the patient recover before trying again.
答案: A · To check pain, toileting, position and personal items before the patient needs to ask
Regular, planned rounding that addresses pain, toileting, positioning and possessions within reach reduces falls and call-light use. The call light stays within reach as well.
答案: A · Switch off the power or unplug the lamp without touching the person
The rescuer must not touch someone still in contact with live current. The power is switched off or the plug pulled first, then the person is assessed and resuscitation is started if needed.
答案: D · 口服抗生素治疗稳定的肺炎患者
被调派的护士应分配到病情稳定、护理使用一般技能的患者。新做气管切开、活动性出血以及因 DKA 使用胰岛素输注,需要本病房专门的经验和密切监测。
答案: A · Vomiting bright red blood, heart rate 120/min
Vomiting blood with a fast pulse suggests bleeding esophageal varices, which can quickly be fatal. The other findings are chronic or stable.
答案: B · 心率和血压
β 受体阻滞剂会降低心率和血压,因此出现心动过缓或低血压时,可能需要暂停给药并通知开药者。
答案: B · Report it as a near miss through the incident reporting system
Near misses are reported so that causes can be studied and systems improved. A just, open culture encourages reporting without blame.
答案: C · 尿量和肾功能
肾脏排泄钾,因此尿量少或肾衰竭可能导致补钾期间发生危险的高钾血症。静脉钾必须稀释,并通过输液泵输注,绝不能静脉推注。核对依据: High potassium level · MedlinePlus (NIH) (2025)
答案: C · Hold the dose and report the results to the prescriber
A high aminoglycoside trough with rising creatinine means the drug is accumulating, which increases the risk of kidney damage and hearing loss. The nurse holds the dose, reports to the prescriber and asks about hearing changes and tinnitus. Only the prescriber or pharmacist changes the regimen.核对依据: Gentamicin sulfate injection - Boxed Warning (US prescribing information) · Pfizer Medical Information (FDA label)
答案: D · It is short-acting, and cholesterol synthesis peaks at night
The liver makes most cholesterol overnight, and short-acting statins such as simvastatin work best when taken in the evening. Atorvastatin and rosuvastatin can be taken at any time of day.
答案: B · Digoxin
ACE inhibitors (or ARBs/ARNI), beta blockers, mineralocorticoid antagonists and SGLT2 inhibitors reduce mortality in heart failure with reduced ejection fraction. Digoxin improves symptoms and reduces admissions without reducing mortality.
答案: C · Myocardial ischaemia
New horizontal or downsloping ST depression during pain suggests myocardial ischaemia, as in unstable angina or NSTEMI. It should be reported immediately with serial ECGs and troponins. ST depression can also reflect reciprocal change opposite a STEMI.
答案: B · Via a mask or humidified device over the neck stoma
A total laryngectomy separates the trachea from the upper airway, so the patient breathes only through the neck stoma. Oxygen and any rescue breaths must be given via the stoma. These patients are "neck breathers" and often carry an alert card.
答案: C · Hypoglycaemia unawareness
Long duration of diabetes and frequent hypos reduce the adrenaline response, so warning symptoms are lost. This greatly increases the risk of severe hypos. Strict avoidance of hypos for some weeks can partly restore awareness, and glucose sensors with alarms help.
答案: D · The other adrenal gland has been suppressed
Excess cortisol from the adenoma suppressed ACTH, so the remaining adrenal gland is shrunken and underactive. Steroid replacement is needed until it recovers, which can take months. Stopping too early risks adrenal crisis.
答案: A · It often builds during the course and can last for weeks
Radiotherapy fatigue usually increases as treatment continues and may persist for weeks or months afterwards. Pacing, light exercise and good sleep and nutrition help.
答案: B · Give analgesia timed so it works during the dressing change
Procedural pain is best managed by giving analgesia so its peak effect matches the procedure. Non-adherent dressings, soaking adherent dressings and allowing the patient to call pauses also help.
答案: B · Fetal hyperinsulinaemia acts as a growth hormone
Maternal glucose crosses the placenta, so the fetal pancreas makes extra insulin, which promotes growth and fat storage. After birth this extra insulin continues and can cause neonatal hypoglycaemia.
答案: C · Acute bilirubin encephalopathy
Lethargy, poor feeding, hypertonia with arching and a high-pitched cry are signs of acute bilirubin encephalopathy. An urgent exchange transfusion may be needed to prevent permanent kernicterus.
答案: B · 避免触诊腹部
触诊腹部可能使肿瘤包膜破裂并扩散癌细胞。床头常挂有标识,提醒工作人员不要触诊。
答案: A · Orbital cellulitis, which needs urgent review and IV antibiotics
Painful eye movements, reduced vision or proptosis with eyelid swelling suggest orbital cellulitis, which can spread to the brain. The child needs urgent assessment, imaging if indicated and IV antibiotics.
答案: A · “我听不到那些声音,但我能看出它们让你很难受。它们在对你说什么?”
护士不争论也不附和,而是说明自己所感知的现实,表达共情,并询问内容,尤其要留意可能使患者或他人面临风险的命令性幻听。
答案: D · Respect the request, join in if comfortable, and offer to call the chaplain
Supporting spiritual needs can reduce distress. The nurse can respond with respect within her own comfort, and refer to chaplaincy or faith leaders, without imposing her own beliefs.
答案: x = 4.8 kg
取整:看舍入位后面的那个数字:5 或更大则进位,4 或更小则保持原数字不变。只对最终答案取整,绝不对中间步骤取整。典型的考试规则:1 mL 或以上的体积取到十分位,低于 1 mL 的体积取到百分位,滴速取整到整滴,体重取到一位小数;务必遵循题目所规定的规则。
答案: D = 100 mcg/min
量纲分析:先写出已知量,再乘以写成分数形式的换算系数(例如 60 min/1 h 或 1 mg/1000 mcg),使每个不需要的单位在分子和分母各出现一次并相互约去。只剩下所求单位时再计算。使用题目给出的等量关系,只对最终答案取整。
答案: V = 1.6 mL
抽取剂量:体积 = (处方剂量/药物浓度) × 药物体积。先换算成相同的单位,再检查该体积是否适合注射器,并落在它的某一个刻度上。
在这支 10 mL 的注射器上,每条小刻度线代表 0.2 mL。
答案: R = 25 mL/h
剂量计算:给药量等于医嘱剂量除以现有药物的规格,再乘以该规格对应的量:给药量 = (医嘱剂量/储备规格) × 储备体积。始终统一单位(先把 g 换成 mg,mg 换成 mcg),并检查答案是否合理。
答案: R = 17 gtt/min
输注速率:输液泵按 mL/h = 体积/时间(小时)设定。重力滴注按每分钟滴数计:gtt/min = 体积 (mL) × 滴系数 (gtt/mL)/时间 (min)。 滴系数印在输液器包装上:普通输液器为 10、15 或 20 gtt/mL(输血器在美国常为 10 gtt/mL,在英国为 15),微量输液器为 60 gtt/mL。务必使用题目或包装给出的滴系数。
床旁取最接近的整滴:17 滴/分。
答案: R = 5 gtt/min
Dose-based infusions: concentration = amount of drug in the bag/bag volume. Pump rate (mL/h) = dose per hour/concentration, and dose per hour = mL/h × concentration. Convert per-minute doses to per-hour (× 60) and keep the mass units the same (1 g = 1000 mg, 1 mg = 1000 mcg).
答案: R = 1.5 mL/h
肝素和胰岛素输注:浓度 = 袋中单位数/袋容量 (units/mL)。泵速 (mL/h) = 每小时单位数/浓度,每小时单位数 = mL/h × 浓度。按体重给药时,先求 units/h = units/kg/h × 体重。推注体积 = 所需单位数/药瓶规格。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: R = 30 mL/h
滴定输注:先求以 mcg/mL 计的浓度(mg × 1000/mL)。按体重给药时,mcg/min = mcg/kg/min × 体重。然后 mL/h = mcg/min × 60/浓度。反推时,mcg/kg/min = mL/h × 浓度/(60 × 体重)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
医嘱是针对患者整体的每分钟剂量,所以不需要体重。
答案: I = 1330 mL
出入量:入量计入所有进入体内的液体(口服液体、静脉输液、静脉用药及冲管液、管饲);冰屑按其体积的一半计。出量计入尿液、引流液、呕吐物和其他丢失。平衡 = 总入量 − 总出量;平衡为负表示净丢失。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: t = 5.3 h
输液时间:时间 (h) = 待输体积 (mL)/速率 (mL/h);使用袋中剩余的体积,而不是袋的容量。已输入体积 = 速率 × 时间。把小数小时换算为小时和分钟时,用小数部分 × 60(0.5 h = 30 min,而不是 50 min)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
约为 5 h 15 min,所以袋子大约在 12:45 输完。
答案: NEWS2 = 4
NEWS2(国家早期预警评分 2,英国皇家内科医师学会 2017):按图表为七个参数分别评分(呼吸频率、量表 1 的 SpO₂、吸空气还是吸氧、收缩压、脉搏、按 ACVPU 量表评定的意识状态和体温),然后把分数相加。临床风险:0–4 为低;任何单项参数得 3 分为中低;5–6 为中;7 或以上为高。总分 5 或以上需要紧急响应。
答案: 中度异常
Apgar 评分:五项体征,每项评 0、1 或 2 分,在出生后 1 分钟和 5 分钟检查。外观(肤色):青紫或苍白 0 分,躯干粉红、四肢青紫 1 分,全身粉红 2 分。脉搏:无 0 分,低于 100 次/分 1 分,100 次/分或以上 2 分。反射(反射应激性):无 0 分,做鬼脸 1 分,哭叫、咳嗽或打喷嚏 2 分。肌张力(活动):松软 0 分,略有屈曲 1 分,活动活跃 2 分。呼吸:无 0 分,缓慢或不规则、哭声微弱 1 分,良好、哭声响亮 2 分。总分 7–10 为令人放心,4–6 为中度异常,0–3 为低。
5 分钟时低于 7 分,通常每 5 分钟重复评分一次,直至 20 分钟。
答案: Osm = 323 mOsm/kg
衍生数值:计算所得的血清渗透压为 2·Na⁺ + 葡萄糖 + 尿素,各值均以 mmol/L 计(葡萄糖和 BUN 以 mg/dL 计时为 2·Na⁺ + 葡萄糖/18 + BUN/2.8);正常约为 275–295 mOsm/kg。P/F 比值是 PaO₂ 除以以小数表示的 FiO₂。海平面的肺泡氧分压为 PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg,A–a 梯度为 PAO₂ − PaO₂。
答案: AGc = 9.5 mmol/L
预期代偿:代谢性酸中毒时,温特公式预测 PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg;实测值高于该范围提示合并呼吸性酸中毒,低于该范围提示合并呼吸性碱中毒。阴离子间隙 AG = Na⁺ − (Cl⁻ + HCO₃⁻),正常约为 8–12 mmol/L,用于区分高阴离子间隙与正常阴离子间隙代谢性酸中毒;低白蛋白会掩盖升高的间隙(白蛋白低于 4.0 的部分,每 g/dL 加 2.5)。Δ 比值 (AG − 12)/(24 − HCO₃⁻) 约在 0.8 到 2 之间符合单纯高间隙酸中毒(有些教材用 1 代替 0.8),低于此范围提示合并正常间隙酸中毒,高于 2 提示合并代谢性碱中毒。
校正后仍在约 8–12 之内。
答案: 心房率 = 300 bpm
节律标准(II 导联):窦性心律每个 QRS 之前都有直立的 P 波,PR 恒定为 0.12–0.20 s,QRS 狭窄:60–100 次/分为正常窦性心律,低于 60 为窦性心动过缓,高于 100 为窦性心动过速。心房颤动:无 P 波,基线呈颤动,R–R 绝对不规则。心房扑动:约 250–350 次/分的锯齿状扑动波,伴固定的传导比例,如 2:1 或 4:1。一度房室传导阻滞:窦性心律,PR 恒定且大于 0.20 s。交界性心律:窄 QRS,40–60 次/分,P 波缺失或倒置(PR 低于 0.12 s,或 P 波在 QRS 之后)。室性早搏(PVC)是提前出现的宽大(0.12 s 或以上)、形态怪异的 QRS,没有 P 波,T 波方向相反,通常有完全性代偿间歇;二联律是指每隔一个搏动就有一个室性早搏。
答案: 尖端扭转型室性心动过速
更多室性心律:尖端扭转型室性心动过速是一种多形性室性心动过速,通常为 150–250 次/分钟,其增宽的波群高度不断变化并围绕基线扭转,先向上几个心搏,再向下。教科书将其与 QT 间期延长联系起来,复苏指南中针对它推荐的药物是硫酸镁。室性自搏心律是一种心室逸搏心律:规则、QRS 增宽(0.12 s 或以上)、无 P 波,频率 20–40 次/分钟(加速性室性自搏心律为 40–100 次/分钟)。单形性室速的增宽波群完全相同,频率超过 100 次/分钟。室颤则是混乱的,没有任何重复的波群。
尖端扭转型室性心动过速是与 QT 间期延长相关的多形性 VT。这里只是识别练习。
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