感染控制与患者安全
方法
- 对每位患者都从标准预防开始:手卫生、针对预期暴露的个人防护装备、安全使用锐器。
- 按传播途径追加预防措施:接触传播(隔离衣、手套)、飞沫传播(外科口罩)、空气传播(N95、负压病房)。
- 保持无菌物品的无菌状态:如有疑问就视为不无菌;更换,绝不擦拭。
- 预防环境中的伤害:防跌倒措施,约束仅作为最后手段,火灾时用 RACE 和 PASS。
- 核对给药的正确原则、两个身份识别信息,以及对高警示药物的额外保障;报告差错和险兆事件。
公式表、每个专题的关键方法步骤和 40 道练习题,完整解答附在最后。
How should the opening of a stoma bag be cut?
A severely malnourished patient is about to start feeding. Which complication is a particular risk?
Which measure is part of the bundle for inserting a central venous catheter to prevent bloodstream infection?
A patient was harmed by a medication error and asks the nurse what happened. Which approach is best?
A patient’s urinary catheter has drained no urine for two hours, and the lower abdomen is swollen. What should the nurse do first?
在资源极其有限的灾难中,一名几乎全身严重烧伤的伤员被标为黑色。哪项原则解释了这个决定?
Which measure helps prevent delirium in older inpatients?
Which sign is often a late finding in hypovolaemic shock in a young, previously fit adult?
How should a blood sample for serum ammonia be handled?
A patient started methimazole for hyperthyroidism 6 weeks ago and now has a fever and a severe sore throat. Which action is most important?
A patient with Addison's disease on hydrocortisone develops a fever with flu. What is the usual advice?
Why is vincristine labelled "for intravenous use only – fatal if given by other routes"?
Which ECG change is classically linked with hyperkalaemia?
为什么高流量氧疗要使用湿化?
A nurse is teaching a patient going home after a mild concussion. Which statement shows a need for further teaching?
A patient has frothy urine and marked leg swelling. Serum albumin is 18 g/L (1.8 g/dL), and BP is normal. The urine shows heavy protein but little blood. What is most likely?
Which risk is particularly linked with tramadol?
一名患者上臂有环形全层烧伤。未来数小时内,最重要的评估是什么?
A newborn's anterior fontanelle is sunken. What should the nurse suspect?
A woman with gestational diabetes asks if she will have diabetes after the baby is born. Which reply is accurate?
How is a child's weight status (for example overweight) assessed?
A 7-year-old has a high fever, refuses to bear weight and has a warm, very tender area over the lower tibia. Which plan is most likely?
一名服用抗精神病药的患者不停地来回踱步,并说他无法静坐。这称为什么?
护士应首先去看哪位患者?
练习题(虚构数值,不作为临床指导)。 一位患者的体温为 35.3 °C。用 °F = °C × 9/5 + 32 把它换算为华氏度T。取到一位小数。
练习题(虚构数值,不作为临床指导)。 一次输注的给药速率为 5 mg/h。请把这个剂量速率D用 mcg/min 表示。取到一位小数。
某患者体重 12 kg,医嘱为单次给药 5 mg/kg。求剂量 D(mg)。
一袋输液在 250 mL 中含 20000 单位药物。医嘱为每小时 1200 单位。泵速 R 应设为多少 mL/h?
用滴系数为 60 滴/mL 的输液器在 12 小时内输入 500 mL。求滴速 R(滴/分)。 取整到最接近的整数。
一袋中含有 1 g 药物,溶于 250 mL。医嘱为每分钟 1 mg。泵速 R 应设为多少 mL/h?
练习题(虚构数值,不作为临床指导)。 一项练习规程要求为体重 96 kg 的患者推注肝素 60 units/kg。药瓶规格为 5 000 units/mL。应抽取多少体积 V? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 一份含dopamine 800 mg、容量 500 mL 的输液以 16 mL/h 输注。患者体重 62 kg。患者接受的剂量 D 是多少 mcg/kg/min? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 记录显示了一名患者在一个 12 小时班次中的出入量。静脉输液在整个班次中按所示速率输注。求总入量 I,以 mL 计。
练习题(虚构数值,不作为临床指导)。 一袋 500 mL 的液体用输液泵以 75 mL/h 输注。到 11:30 时已输入 300 mL。还要多少小时 t 袋子才会输完? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 用 Morse 跌倒评分评估一位练习患者:过去 3 个月内的跌倒史: 是; 次要诊断: 否; 行走辅助: 扶着家具; 静脉输液或封管: 否; 步态: 受损; 精神状态: 高估或忘记自身局限。求 Morse 总分MFS。
练习题(虚构数值,不作为临床指导)。 对这些观察结果使用 NEWS2 图表(SpO₂ 量表 1):呼吸频率 18 次/分,SpO₂ 97%吸室内空气,血压 90/54 mmHg,脉搏 76 次/分,清醒,体温 37.9 °C。患者属于哪个临床风险组?点击它。
某练习血气显示 PaCO₂ 75 mmHg (10.0 kPa)。利用规则:在慢性呼吸性酸中毒中,PaCO₂ 每比 40 高出 10 mmHg,HCO₃⁻ 升高 3.5 mmol/L,以HCO₃⁻ 24 mmol/L 为起点,求预期HCO₃⁻。
某练习血气显示代谢性碱中毒,HCO₃⁻ 40 mmol/L。用预期 PaCO₂ = 0.7·HCO₃⁻ + 21 求预期PaCO₂。
解读这条 II 导联心律条带。这是什么节律?点击你的答案。
这条 II 导联心电图显示房室传导阻滞,所以心房和心室以不同的频率搏动。测量 P–P 间期,求出心房率(单位:次/分,1500 法,取整数)。
答案: B · To fit closely around the stoma without pressing on it
The opening should fit snugly so stoma output does not reach the skin, but not so tight that it damages the stoma. Stomas shrink in the weeks after surgery, so the size is re-measured.
答案: D · Refeeding syndrome with low phosphate, potassium and magnesium
When feeding restarts after starvation, insulin release drives phosphate, potassium and magnesium into the cells. Low levels can cause heart failure and arrhythmias, so feeding starts slowly and bloods are monitored.
答案: A · Chlorhexidine-alcohol skin antisepsis and maximal sterile barrier precautions
The insertion bundle includes hand hygiene, chlorhexidine-alcohol skin prep, maximal barrier precautions (cap, mask, sterile gown, sterile gloves and a full body drape) and avoiding the femoral site in adults. Routine replacement and routine antibiotics are not recommended.
答案: C · Be honest that an error occurred and involve the provider and team in disclosure per policy
Open, honest disclosure of errors is an ethical duty and part of a safety culture. The nurse follows policy, which usually involves the provider and risk team, and does not hide or blame.
答案: D · Check the tubing for kinks or obstruction
Sudden lack of drainage with a full bladder usually means a kinked or blocked catheter. The nurse checks the tubing and position first, then follows the policy for irrigation or replacement.
答案: C · 为最多的人做最大的好事
在大规模伤亡事件中,资源用在能挽救最多生命的地方。即使给予全面治疗也不太可能存活的伤员接受安宁照护,而工作人员则救治可挽救的伤员。在日常分诊中,通常先看病情最重的患者。
答案: B · Reorientation, glasses and hearing aids in use, and good sleep and hydration
Multicomponent prevention, including orientation, sensory aids, hydration, nutrition, mobility, sleep and avoiding unnecessary moves or drugs, reduces delirium.
答案: A · A fall in blood pressure
Young adults compensate for blood loss with tachycardia and vasoconstriction, so blood pressure may stay normal until a large volume is lost. Hypotension is therefore a late and serious sign.
答案: C · Placed on ice and sent to the laboratory at once
Ammonia can rise in a standing sample as red cells and proteins break down. The sample is usually placed on ice and analyzed promptly to avoid a falsely high result.
答案: D · Hold the drug and arrange an urgent white cell and neutrophil count
Methimazole and propylthiouracil can cause agranulocytosis, often in the first months of therapy. Fever or sore throat must be reported at once; the drug is held and a CBC with differential is checked. Infection is treated urgently if neutrophils are low.
答案: B · Increase the dose as instructed (sick-day rules) and seek help if vomiting
During illness, the body needs more cortisol, so patients usually double their glucocorticoid dose as instructed. If they cannot keep tablets down, they need injectable hydrocortisone and urgent care.
答案: C · Accidental intrathecal injection causes fatal ascending neurotoxicity
Vincristine given intrathecally causes ascending paralysis and death. To prevent this, it is usually given in a small IV bag rather than a syringe and kept separate from intrathecal drugs.
答案: C · Tall, peaked T waves
Rising potassium causes tall, tented T waves, then a flattened P wave, a prolonged PR interval and a widening QRS that can progress to ventricular fibrillation or asystole. U waves suggest hypokalaemia; a sawtooth baseline is atrial flutter.
答案: A · 高流量的干燥气体会使气道干燥,分泌物变稠
高流量干燥气体超出了鼻腔湿化的能力,导致黏膜干燥、分泌物变稠和不适。加温加湿的高流量系统可提高耐受性并帮助清除分泌物。
答案: C · "A few drinks tonight will help me relax and sleep."
After a head injury, alcohol and sedatives should be avoided because they can mask drowsiness and confusion. A responsible adult should stay with the patient, and worsening headache, repeated vomiting, confusion or drowsiness mean they must return.
答案: B · Nephrotic syndrome
Heavy proteinuria, very low albumin and oedema point to nephrotic syndrome. Nephritic syndrome is mainly haematuria with hypertension and reduced urine output. The cause is investigated, often with a biopsy.
答案: A · Serotonin syndrome with some antidepressants, and seizures
Tramadol is a weak opioid that also inhibits serotonin and noradrenaline reuptake. It can lower the seizure threshold and cause serotonin syndrome with SSRIs and other serotonergic drugs.
答案: D · 手部的血液循环和感觉
全层焦痂没有弹性。随着水肿的发展,压力升高,可影响循环(胸部烧伤时则影响呼吸)。定期检查脉搏、颜色、毛细血管再充盈、疼痛和感觉,可及早发现这一问题;可能需要焦痂切开术。
答案: B · Dehydration
A sunken fontanelle suggests dehydration. A tense or bulging fontanelle when the baby is calm and upright can indicate raised intracranial pressure, such as from meningitis or hydrocephalus.
答案: B · It usually resolves, but her risk of type 2 diabetes stays higher
Gestational diabetes usually resolves after birth, but the risk of later type 2 diabetes is much higher. She should have a glucose test after birth and regular screening, and keep up a healthy weight and activity.
答案: B · BMI plotted on an age- and sex-specific centile chart
In children, BMI is interpreted using age- and sex-specific centile charts, because normal BMI changes with growth. Adult cut-offs such as 25 and 30 do not apply to children.
答案: B · Blood cultures and prompt IV antibiotics for possible osteomyelitis
Acute osteomyelitis in children is most often caused by Staphylococcus aureus. Blood cultures are taken and IV antibiotics started promptly, followed by a long course to prevent bone damage and chronic infection.
答案: A · 静坐不能
静坐不能是一种内心的不安,伴有想要活动的冲动。它令人痛苦,可能被误认为是激越或焦虑,并与不依从治疗和自杀风险增加有关。
答案: D · 一名新入院的患者,说声音在告诉他从窗户跳出去
要求自伤的命令性幻听提示即时的安全风险。细微震颤是锂盐常见的副作用,其他要求可以稍候。
答案: T = 95.5 °F
温度:°C = (°F − 32) × 5/9,°F = °C × 9/5 + 32。从 °F 换算时先减 32 再乘,从 °C 换算时先乘再加 32。快速核对:37 °C 为 98.6 °F,每 1 °C 相当于 1.8 °F。
答案: D = 83.3 mcg/min
量纲分析:先写出已知量,再乘以写成分数形式的换算系数(例如 60 min/1 h 或 1 mg/1000 mcg),使每个不需要的单位在分子和分母各出现一次并相互约去。只剩下所求单位时再计算。使用题目给出的等量关系,只对最终答案取整。
答案: D = 60 mg
剂量计算:给药量等于医嘱剂量除以现有药物的规格,再乘以该规格对应的量:给药量 = (医嘱剂量/储备规格) × 储备体积。始终统一单位(先把 g 换成 mg,mg 换成 mcg),并检查答案是否合理。
答案: R = 15 mL/h
剂量计算:给药量等于医嘱剂量除以现有药物的规格,再乘以该规格对应的量:给药量 = (医嘱剂量/储备规格) × 储备体积。始终统一单位(先把 g 换成 mg,mg 换成 mcg),并检查答案是否合理。
答案: R = 42 gtt/min
输注速率:输液泵按 mL/h = 体积/时间(小时)设定。重力滴注按每分钟滴数计:gtt/min = 体积 (mL) × 滴系数 (gtt/mL)/时间 (min)。 滴系数印在输液器包装上:普通输液器为 10、15 或 20 gtt/mL(输血器在美国常为 10 gtt/mL,在英国为 15),微量输液器为 60 gtt/mL。务必使用题目或包装给出的滴系数。
床旁取最接近的整滴:42 滴/分。
答案: R = 15 mL/h
Dose-based infusions: concentration = amount of drug in the bag/bag volume. Pump rate (mL/h) = dose per hour/concentration, and dose per hour = mL/h × concentration. Convert per-minute doses to per-hour (× 60) and keep the mass units the same (1 g = 1000 mg, 1 mg = 1000 mcg).
答案: V = 1.2 mL
肝素和胰岛素输注:浓度 = 袋中单位数/袋容量 (units/mL)。泵速 (mL/h) = 每小时单位数/浓度,每小时单位数 = mL/h × 浓度。按体重给药时,先求 units/h = units/kg/h × 体重。推注体积 = 所需单位数/药瓶规格。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: D = 6.9 mcg/kg/min
滴定输注:先求以 mcg/mL 计的浓度(mg × 1000/mL)。按体重给药时,mcg/min = mcg/kg/min × 体重。然后 mL/h = mcg/min × 60/浓度。反推时,mcg/kg/min = mL/h × 浓度/(60 × 体重)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: I = 1220 mL
出入量:入量计入所有进入体内的液体(口服液体、静脉输液、静脉用药及冲管液、管饲);冰屑按其体积的一半计。出量计入尿液、引流液、呕吐物和其他丢失。平衡 = 总入量 − 总出量;平衡为负表示净丢失。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: t = 2.7 h
输液时间:时间 (h) = 待输体积 (mL)/速率 (mL/h);使用袋中剩余的体积,而不是袋的容量。已输入体积 = 速率 × 时间。把小数小时换算为小时和分钟时,用小数部分 × 60(0.5 h = 30 min,而不是 50 min)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
约为 2 h 40 min,所以袋子大约在 14:10 输完。
答案: MFS = 90
Morse 跌倒评分:六个条目。跌倒史:否 0 分,是 25 分。次要诊断:否 0 分,是 15 分。行走辅助:无、卧床休息或护士协助 0 分;拐杖、手杖或助行器 15 分;扶着家具 30 分。静脉输液或封管:否 0 分,是 20 分。步态:正常、卧床休息或轮椅 0 分;虚弱 10 分;受损 20 分。精神状态:了解自身局限 0 分;高估或忘记自身局限 15 分。总分为 0 至 125。各医院的风险分界值不同;常用的一套是 0–24 低风险,25–44 中度风险,45 及以上为高风险。
答案: 中低
NEWS2(国家早期预警评分 2,英国皇家内科医师学会 2017):按图表为七个参数分别评分(呼吸频率、量表 1 的 SpO₂、吸空气还是吸氧、收缩压、脉搏、按 ACVPU 量表评定的意识状态和体温),然后把分数相加。临床风险:0–4 为低;任何单项参数得 3 分为中低;5–6 为中;7 或以上为高。总分 5 或以上需要紧急响应。
即使总分低,单项得 3 分也需要紧急会诊。
答案: HCO₃⁻ = 36.25 mmol/L
预期代偿:代谢性酸中毒时,温特公式预测 PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg;实测值高于该范围提示合并呼吸性酸中毒,低于该范围提示合并呼吸性碱中毒。阴离子间隙 AG = Na⁺ − (Cl⁻ + HCO₃⁻),正常约为 8–12 mmol/L,用于区分高阴离子间隙与正常阴离子间隙代谢性酸中毒;低白蛋白会掩盖升高的间隙(白蛋白低于 4.0 的部分,每 g/dL 加 2.5)。Δ 比值 (AG − 12)/(24 − HCO₃⁻) 约在 0.8 到 2 之间符合单纯高间隙酸中毒(有些教材用 1 代替 0.8),低于此范围提示合并正常间隙酸中毒,高于 2 提示合并代谢性碱中毒。
答案: PaCO₂ = 49 mmHg
预期代偿:代谢性酸中毒时,温特公式预测 PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg;实测值高于该范围提示合并呼吸性酸中毒,低于该范围提示合并呼吸性碱中毒。阴离子间隙 AG = Na⁺ − (Cl⁻ + HCO₃⁻),正常约为 8–12 mmol/L,用于区分高阴离子间隙与正常阴离子间隙代谢性酸中毒;低白蛋白会掩盖升高的间隙(白蛋白低于 4.0 的部分,每 g/dL 加 2.5)。Δ 比值 (AG − 12)/(24 − HCO₃⁻) 约在 0.8 到 2 之间符合单纯高间隙酸中毒(有些教材用 1 代替 0.8),低于此范围提示合并正常间隙酸中毒,高于 2 提示合并代谢性碱中毒。
升高是有限度的:仅靠代偿,PaCO₂ 很少超过约 55 mmHg。
答案: 室性二联律
节律标准(II 导联):窦性心律每个 QRS 之前都有直立的 P 波,PR 恒定为 0.12–0.20 s,QRS 狭窄:60–100 次/分为正常窦性心律,低于 60 为窦性心动过缓,高于 100 为窦性心动过速。心房颤动:无 P 波,基线呈颤动,R–R 绝对不规则。心房扑动:约 250–350 次/分的锯齿状扑动波,伴固定的传导比例,如 2:1 或 4:1。一度房室传导阻滞:窦性心律,PR 恒定且大于 0.20 s。交界性心律:窄 QRS,40–60 次/分,P 波缺失或倒置(PR 低于 0.12 s,或 P 波在 QRS 之后)。室性早搏(PVC)是提前出现的宽大(0.12 s 或以上)、形态怪异的 QRS,没有 P 波,T 波方向相反,通常有完全性代偿间歇;二联律是指每隔一个搏动就有一个室性早搏。
答案: 心房率 = 71 bpm
房室传导阻滞:逐个标出 P 波,检查哪些 P 波后面跟着 QRS。一度:每个 P 波都下传,PR 恒定且大于 0.20 s。二度 I 型(Mobitz I,文氏现象):PR 逐搏延长,直到一个 P 波未下传,然后周期重新开始(成组搏动)。二度 II 型(Mobitz II):下传搏动的 PR 保持恒定,P 波突然不下传;QRS 常增宽。三度(完全性)阻滞:P 波和 QRS 波群各自规则但互相独立,PR 随机变化,心房率快于逸搏率(交界性逸搏 40–60 次/分,QRS 窄;室性逸搏 20–40 次/分,QRS 宽)。2:1 阻滞仅凭一份条带无法判断是 I 型还是 II 型。
2:1 房室传导阻滞:每隔一个 P 波不下传,所以心房率是心室率的两倍。
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