感染控制与患者安全
方法
- 对每位患者都从标准预防开始:手卫生、针对预期暴露的个人防护装备、安全使用锐器。
- 按传播途径追加预防措施:接触传播(隔离衣、手套)、飞沫传播(外科口罩)、空气传播(N95、负压病房)。
- 保持无菌物品的无菌状态:如有疑问就视为不无菌;更换,绝不擦拭。
- 预防环境中的伤害:防跌倒措施,约束仅作为最后手段,火灾时用 RACE 和 PASS。
- 核对给药的正确原则、两个身份识别信息,以及对高警示药物的额外保障;报告差错和险兆事件。
公式表、每个专题的关键方法步骤和 40 道练习题,完整解答附在最后。
When opening a sterile pack on a table, which flap is opened first?
A collapsed patient is unresponsive and making only occasional slow gasps. What should the nurse do?
Before helping a patient from bed into a wheelchair, what should the nurse do with the wheelchair?
A patient is on contact precautions. Which task is appropriate for the nurse to delegate to assistive personnel?
One hour after a vaginal birth, the nurse finds a soft, boggy uterus and heavy bleeding. What is the first action?
一个团队包括一名 RN、一名 LPN/LVN 和一名护理助理。哪种分工最恰当?
Which pattern is typical of relapsing–remitting multiple sclerosis?
Which feature suggests moisture-associated skin damage rather than a pressure ulcer?
A patient on carbamazepine becomes confused and has a headache. Which laboratory result would most likely explain this?
哪一组结果最能代表缺铁性贫血?
A patient starting sulfasalazine should be told about which harmless effect?
How does aripiprazole differ from most other antipsychotics?
After a bronchoscopy with throat anaesthesia, when can the patient eat and drink?
一名患者的胸腔引流管被意外拔出。应立即采取什么措施?
Which headache feature most suggests raised intracranial pressure from a brain tumour?
A patient with SIADH is taught about a fluid restriction. Which statement shows a need for further teaching?
After a spinal anaesthetic, which nursing check is particularly important?
一名使用阿片类药物 PCA 的患者经面罩吸氧。SpO₂ 97%,呼吸频率 11 次/分,但现在很难唤醒。护士应得出什么结论?
During newborn resuscitation, what is the ratio of chest compressions to breaths?
A woman has had a large postpartum haemorrhage and is receiving several units of blood. Which other complication should the nurse watch for?
Which injury in an infant is most suggestive of physical abuse?
A 12-year-old with asthma has been prescribed a preventer inhaler (inhaled corticosteroid) to take every day. Which statement shows a need for further teaching?
A patient taking valproate is starting lamotrigine. Why must lamotrigine be increased especially slowly?
During a ward community meeting, several patients complain that the ward is too noisy at night. What reflects a therapeutic milieu?
练习题(虚构数值,不作为临床指导)。 一次小剂量注射的计算得到 0.54618 mL。 本练习的规则是:低于 1 mL 的体积取到最接近的百分之一 mL。你记录的数值x是多少?
练习题(虚构数值,不作为临床指导)。 一个班次中,患者摄入了2 杯 / 茶, 3 tbsp / 液体营养补充剂, ½ tsp / 止咳糖浆, 4 fl oz / 果汁。按给出的等量关系,求以 mL 表示的口服总摄入量V。
一个药瓶中含有 500 mg 的粉末。标签上写着:加入 1.8 mL 注射用水,得到总容量 2 mL。医嘱为 150 mg。你应给予复溶后溶液的多少容量 V?
处方为 600 单位的药物,药液规格为 5000 单位/mL。请用 1 mL 注射器抽取剂量:应给多少体积 V?
滴注以 60 gtt/min 的速度通过滴系数为 60 gtt/mL 的输液器。患者在 8 小时内接受多少毫升 V?
一组输液以 25 滴/分的速度经 15 滴/mL 的输液器滴注。袋中还剩 300 mL。还需多少小时 t 才会滴完?
练习题(虚构数值,不作为临床指导)。 一袋中含肝素 20 000 单位,容量 500 mL。医嘱为 18 units/kg/h,患者体重 97 kg。输液泵速率 R 应设为多少 mL/h? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 一名体重 76 kg 的患者的医嘱为nitroglycerin 10 mcg/min。输液袋中含 50 mg,容量 250 mL。求泵速 R,以 mL/h 计。 保留一位小数。
练习题(虚构数值,不作为临床指导)。 记录显示了一名患者在一个 12 小时班次中的出入量。静脉输液在整个班次中按所示速率输注。求总入量 I,以 mL 计。
练习题(虚构数值,不作为临床指导)。 一份 500 mL 的输液于 06:00 开始以 120 mL/h 输注。3 小时后速率改为 200 mL/h,之后不再改变。从开始算起多少小时 t 后袋子会输完? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 用 Morse 跌倒评分评估一位练习患者:过去 3 个月内的跌倒史: 是; 次要诊断: 是; 行走辅助: 拐杖、手杖或助行器; 静脉输液或封管: 是; 步态: 虚弱; 精神状态: 高估或忘记自身局限。求 Morse 总分MFS。
练习题(虚构数值,不作为临床指导)。 一名成人体重 121 kg,身高 180 cm。计算 BMI 并点击 WHO 体重分类。
某练习动脉血气显示 pH 7.27,PaCO₂ 18 mmHg (2.4 kPa),HCO₃⁻ 8 mmol/L。原发性紊乱是代谢性酸中毒。代偿到什么程度?点选你的答案。
练习数值:Na⁺ 134,Cl⁻ 105,HCO₃⁻ 21 mmol/L,白蛋白 17 g/L。求经白蛋白校正的阴离子间隙 AGc = AG + 0.25·(40 − 白蛋白)。
在这条规则的 II 导联心电图上测量 QT 间期和 R–R 间期,然后用 Bazett 公式 QTc = QT/√RR(均以秒计)计算经心率校正的QTc。答案以秒表示,保留三位小数。
这条 II 导联心电图显示心房与心室之间存在传导问题。这是什么节律?点击你的答案。
答案: C · The flap furthest away from you
Opening the far flap first means the nurse never reaches across the exposed sterile contents. The side flaps follow, and the nearest flap is opened last.
答案: D · Treat it as not breathing normally, call for help and start CPR
Agonal gasps are common in the first minutes after cardiac arrest. They must not be mistaken for breathing; CPR is started and an AED fetched straight away.
答案: A · Lock the brakes and place it close to the bed on the patient’s stronger side
Locked brakes stop the chair rolling away during the transfer. Placing it close to the bed on the stronger side lets the patient lead with their strong leg.
答案: D · Helping the patient bathe while wearing a gown and gloves
Assistive personnel can carry out routine care for a stable patient, using the correct PPE. Assessment, teaching and clinical judgement, such as deciding when to stop precautions, cannot be delegated to them.
答案: C · Massage the fundus
Uterine atony is the most common cause of postpartum hemorrhage. Fundal massage helps the uterus contract; the nurse then calls for help and gives prescribed uterotonics if bleeding continues.
答案: B · RN:新入院患者;LPN/LVN:稳定患者的用药;助理:卫生护理
RN 负责评估和复杂护理,LPN/LVN 护理稳定患者并给予常规药物,助理负责常规的卫生护理和测量。其他选项把任务分配到了超出该人员工作范围的人。
答案: A · Attacks of symptoms, such as visual loss or numbness, that improve between relapses
MS causes demyelination in the brain and spinal cord. Many patients first have attacks such as optic neuritis or sensory symptoms, with partial or full recovery between relapses.
答案: A · Diffuse, superficial redness in a skin fold, not over a bony prominence
Moisture lesions are superficial, irregular and often in skin folds or areas exposed to incontinence. Pressure ulcers usually occur over bony prominences or under devices and may be deeper.
答案: C · A low serum sodium
Carbamazepine (and oxcarbazepine) can cause hyponatremia by increasing the effect of ADH, which can cause confusion, headache and seizures. The drug can also cause serious blood disorders, so the CBC is monitored.核对依据: Syndrome of Inappropriate Antidiuretic Hormone Secretion · StatPearls (NCBI Bookshelf) (2023); Carbamazepine · StatPearls (NCBI Bookshelf) (2023)
答案: C · 血红蛋白低、红细胞小(MCV 低)和铁蛋白低
缺铁引起小细胞性贫血(MCV 低),铁储备低(铁蛋白低)。红细胞大提示维生素 B12 或叶酸缺乏。核对依据: Ferritin Blood Test · MedlinePlus (NIH) (2025); RBC indices · MedlinePlus (NIH) (2026)
答案: B · Orange-yellow colouring of the urine
Sulfasalazine can colour urine and sometimes skin and contact lenses orange-yellow. More serious adverse effects include blood disorders and rash, so blood counts are monitored.
答案: A · It is a partial agonist at dopamine D2 receptors
Aripiprazole is a D2 partial agonist, reducing dopamine activity where it is high and providing some where it is low. It causes less weight gain and prolactin rise than many antipsychotics, but akathisia is common.
答案: C · When the gag and cough reflexes have returned
Local anaesthetic sprayed on the throat abolishes the gag and cough reflexes for a time, so food or fluid could be aspirated. The nurse checks that the reflexes have returned (often after about one to two hours) before giving sips of water and then food.
答案: C · 用无菌密闭敷料封闭伤口并呼救
应立即用无菌密闭敷料覆盖伤口,以防空气进入胸腔。评估患者有无气胸复发或张力性气胸(呼吸困难加重、饱和度下降、心动过速、气管移位),并通知医疗团队。绝不能重新插入引流管。
答案: A · Worse on waking and on coughing, with vomiting
Headaches from raised ICP are often worse on waking, when coughing, sneezing or bending, and may come with vomiting or visual changes. A new headache with these features needs prompt assessment.
答案: B · "If I feel thirsty, I can drink as much water as I like."
In SIADH, the body keeps too much water. Drinking freely when thirsty would lower the sodium further. All fluids count towards the restriction. Daily weights and reporting neurological symptoms are correct.
答案: C · Return of leg sensation and movement, and passing urine
The nurse monitors the level of the block, recovery of leg movement and sensation, BP and bladder function. Urinary retention is common, and early mobilisation is only safe once motor function returns.
答案: D · 很可能是阿片类药物中毒;氧气可能掩盖了通气不足
补充氧气可使 SpO₂ 保持正常,而 CO₂ 却因通气不足而升高。镇静加深是阿片类药物中毒的早期征象。护士应停止 PCA,刺激患者,呼叫援助并遵循纳洛酮方案,密切监测呼吸频率、深度和镇静程度。
答案: B · 3 compressions to 1 breath
Newborn resuscitation uses a 3:1 ratio, about 90 compressions and 30 breaths per minute, with the two-thumb technique on the lower third of the sternum.
答案: B · Coagulopathy from loss of clotting factors
Massive haemorrhage and transfusion of red cells can deplete clotting factors and platelets, leading to further bleeding. Massive transfusion protocols include plasma, platelets and sometimes fibrinogen.
答案: A · Posterior rib fractures
Posterior rib fractures in infants are highly suggestive of abuse because they usually result from forceful squeezing of the chest. Bruises on the shins and grazes are common in mobile children.
答案: A · "I stop taking my preventer inhaler whenever I've had a few good days."
Preventer (inhaled corticosteroid) inhalers reduce airway inflammation and must be taken daily as prescribed, even when the child feels well. Carrying a reliever, rinsing the mouth and using a spacer are correct.
答案: C · Valproate raises lamotrigine levels, which increases the risk of a serious rash
Valproate inhibits the metabolism of lamotrigine, roughly doubling its levels. Because lamotrigine rash, including Stevens-Johnson syndrome, is linked to rapid dose increases, a slower titration is used.
答案: A · Discuss the problem openly and involve patients in finding a solution
In a therapeutic milieu, the ward environment itself is used for treatment. Shared decision-making in community meetings builds responsibility, social skills and trust.
答案: x = 0.55 mL
取整:看舍入位后面的那个数字:5 或更大则进位,4 或更小则保持原数字不变。只对最终答案取整,绝不对中间步骤取整。典型的考试规则:1 mL 或以上的体积取到十分位,低于 1 mL 的体积取到百分位,滴速取整到整滴,体重取到一位小数;务必遵循题目所规定的规则。
答案: V = 647.5 mL
家用计量和体重:护理考试使用取整的等量关系:1 茶匙(tsp)= 5 mL,1 汤匙(tbsp)= 15 mL = 3 tsp,1 液量盎司(fl oz)= 30 mL = 2 tbsp,1 杯 = 8 fl oz = 240 mL。体重方面,1 kg = 2.2 lb,1 lb = 16 oz;长度方面,1 英寸 = 2.54 cm。设置换算时,要让你不需要的单位相互约去。
答案: V = 0.6 mL
Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.
答案: V = 0.12 mL
抽取剂量:体积 = (处方剂量/药物浓度) × 药物体积。先换算成相同的单位,再检查该体积是否适合注射器,并落在它的某一个刻度上。
在这支 1 mL 的注射器上,每条小刻度线代表 0.01 mL。
答案: V = 480 mL
Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.
答案: t = 3 h
输注速率:输液泵按 mL/h = 体积/时间(小时)设定。重力滴注按每分钟滴数计:gtt/min = 体积 (mL) × 滴系数 (gtt/mL)/时间 (min)。 滴系数印在输液器包装上:普通输液器为 10、15 或 20 gtt/mL(输血器在美国常为 10 gtt/mL,在英国为 15),微量输液器为 60 gtt/mL。务必使用题目或包装给出的滴系数。
答案: R = 43.7 mL/h
肝素和胰岛素输注:浓度 = 袋中单位数/袋容量 (units/mL)。泵速 (mL/h) = 每小时单位数/浓度,每小时单位数 = mL/h × 浓度。按体重给药时,先求 units/h = units/kg/h × 体重。推注体积 = 所需单位数/药瓶规格。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: R = 3 mL/h
滴定输注:先求以 mcg/mL 计的浓度(mg × 1000/mL)。按体重给药时,mcg/min = mcg/kg/min × 体重。然后 mL/h = mcg/min × 60/浓度。反推时,mcg/kg/min = mL/h × 浓度/(60 × 体重)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
医嘱是针对患者整体的每分钟剂量,所以不需要体重。
答案: I = 1940 mL
出入量:入量计入所有进入体内的液体(口服液体、静脉输液、静脉用药及冲管液、管饲);冰屑按其体积的一半计。出量计入尿液、引流液、呕吐物和其他丢失。平衡 = 总入量 − 总出量;平衡为负表示净丢失。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: t = 3.7 h
输液时间:时间 (h) = 待输体积 (mL)/速率 (mL/h);使用袋中剩余的体积,而不是袋的容量。已输入体积 = 速率 × 时间。把小数小时换算为小时和分钟时,用小数部分 × 60(0.5 h = 30 min,而不是 50 min)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
约为 3 h 42 min,所以袋子大约在 09:42 输完。
答案: MFS = 100
Morse 跌倒评分:六个条目。跌倒史:否 0 分,是 25 分。次要诊断:否 0 分,是 15 分。行走辅助:无、卧床休息或护士协助 0 分;拐杖、手杖或助行器 15 分;扶着家具 30 分。静脉输液或封管:否 0 分,是 20 分。步态:正常、卧床休息或轮椅 0 分;虚弱 10 分;受损 20 分。精神状态:了解自身局限 0 分;高估或忘记自身局限 15 分。总分为 0 至 125。各医院的风险分界值不同;常用的一套是 0–24 低风险,25–44 中度风险,45 及以上为高风险。
答案: 肥胖 II 级
体质指数:BMI = 体重(kg)/身高(m)²,身高要先换算为米。使用磅和英寸时,BMI = 703 × 体重(lb)/身高(in)²。WHO 成人分类:低于 18.5 为体重过轻,18.5–24.9 为健康体重,25.0–29.9 为超重,30.0–34.9 为肥胖 I 级,35.0–39.9 为肥胖 II 级,40 及以上为肥胖 III 级。
答案: 部分代偿
解读血气(ROME):先看 pH:低于 7.35 为酸血症,高于 7.45 为碱血症。然后找出能解释它的指标。PaCO₂(正常 35–45 mmHg,4.7–6.0 kPa)是呼吸方面的指标,在呼吸性紊乱中与 pH 反向(Opposite)变化;HCO₃⁻(正常 22–26 mmol/L)是代谢方面的指标,与 pH 同向变化(Respiratory Opposite, Metabolic Equal,即呼吸性相反,代谢性相同)。另一个指标显示代偿情况:正常表示未代偿;沿着使 pH 回升的方向异常、而 pH 仍然异常,表示部分代偿;pH 正常而两个指标都异常,表示完全代偿。各实验室的范围略有差异;这些是练习用数值。
答案: AGc = 13.75 mmol/L
预期代偿:代谢性酸中毒时,温特公式预测 PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg;实测值高于该范围提示合并呼吸性酸中毒,低于该范围提示合并呼吸性碱中毒。阴离子间隙 AG = Na⁺ − (Cl⁻ + HCO₃⁻),正常约为 8–12 mmol/L,用于区分高阴离子间隙与正常阴离子间隙代谢性酸中毒;低白蛋白会掩盖升高的间隙(白蛋白低于 4.0 的部分,每 g/dL 加 2.5)。Δ 比值 (AG − 12)/(24 − HCO₃⁻) 约在 0.8 到 2 之间符合单纯高间隙酸中毒(有些教材用 1 代替 0.8),低于此范围提示合并正常间隙酸中毒,高于 2 提示合并代谢性碱中毒。
校正后高于约 12:阴离子间隙升高。
答案: QTc = 0.52 s
QT 与 QTc:QT 间期从 QRS 波群起点到 T 波终点。它随心率加快而缩短,因此要用以秒为单位的 R–R 间期按心率校正:Bazett QTc = QT/√RR,Fridericia QTc = QT/∛RR。多数教科书使用 Bazett 公式;它在心率快时校正过度,此时宜用 Fridericia。各参考标准的界限不同:QTc 男性高于约 0.45 s、女性高于约 0.46 s 通常称为延长,高于 0.50 s 称为明显延长。
高于 0.50 s:明显延长。(520 ms)
答案: 二度 I 型房室传导阻滞(文氏现象)
房室传导阻滞:逐个标出 P 波,检查哪些 P 波后面跟着 QRS。一度:每个 P 波都下传,PR 恒定且大于 0.20 s。二度 I 型(Mobitz I,文氏现象):PR 逐搏延长,直到一个 P 波未下传,然后周期重新开始(成组搏动)。二度 II 型(Mobitz II):下传搏动的 PR 保持恒定,P 波突然不下传;QRS 常增宽。三度(完全性)阻滞:P 波和 QRS 波群各自规则但互相独立,PR 随机变化,心房率快于逸搏率(交界性逸搏 40–60 次/分,QRS 窄;室性逸搏 20–40 次/分,QRS 宽)。2:1 阻滞仅凭一份条带无法判断是 I 型还是 II 型。
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