感染控制与患者安全
方法
- 对每位患者都从标准预防开始:手卫生、针对预期暴露的个人防护装备、安全使用锐器。
- 按传播途径追加预防措施:接触传播(隔离衣、手套)、飞沫传播(外科口罩)、空气传播(N95、负压病房)。
- 保持无菌物品的无菌状态:如有疑问就视为不无菌;更换,绝不擦拭。
- 预防环境中的伤害:防跌倒措施,约束仅作为最后手段,火灾时用 RACE 和 PASS。
- 核对给药的正确原则、两个身份识别信息,以及对高警示药物的额外保障;报告差错和险兆事件。
公式表、每个专题的关键方法步骤和 40 道练习题,完整解答附在最后。
为什么开具氧疗医嘱时必须注明目标血氧饱和度范围?
A patient who had a GCS of 15 this morning now opens their eyes only to voice and is confused. What should the nurse do?
A newly hired nurse had BCG vaccine as a child. Which TB screening test is usually preferred?
一名意识混乱、戴着腕部约束带的患者,一只手的手指发凉、苍白,该侧桡动脉搏动减弱。护士首先应做什么?
A patient has a reddened area on the sacrum that does not blanch when pressed. What is the priority action?
A patient arrives at the emergency department with a plan to end their life, but has normal vital signs. Which ESI level fits best?
低钠血症患者应特别监测:
A patient starting a DOAC is taught about missed doses. Which statement shows a need for further teaching?
After surgery for colon cancer, a patient's CEA had fallen to normal, but it has been rising over the last two checks. What does this most likely suggest?
Which cerebrospinal fluid (CSF) pattern most strongly suggests bacterial meningitis?
阿昔洛韦主要用于治疗由什么引起的感染?
An older patient who has taken omeprazole for many years has muscle cramps, tremor and an irregular heartbeat. Which lab finding is most likely linked to the drug?
A patient's blood pressure is 120/60 mmHg. What is the approximate mean arterial pressure?
After a car crash, a patient is severely breathless with absent breath sounds on the right, a deviated trachea, distended neck veins and BP 76/40 mmHg. What is the immediate management?
A conscious patient with a glucose of 3.1 mmol/L (56 mg/dL) can swallow safely. Which is the best first treatment?
A patient taking digoxin has a potassium of 2.9 mmol/L. Why is this especially dangerous?
When is cold therapy most useful for pain?
Using the adult rule of nines, what is the total burn area of the whole right arm plus the whole front of the trunk (both with partial-thickness burns)?
第 3 天时,健康的母乳喂养新生儿预期出现哪种表现?
A woman at 28 weeks has itching, and her liver tests and bile acids are raised. Which advice is most important?
How is a child's weight status (for example overweight) assessed?
The parents of a 5-year-old refuse a life-saving blood transfusion for religious reasons. What generally happens?
Which item is part of a safety plan for a person experiencing domestic violence?
During a ward community meeting, several patients complain that the ward is too noisy at night. What reflects a therapeutic milieu?
练习题(虚构数值,不作为临床指导)。 一位患者的体温为 35.4 °C。用 °F = °C × 9/5 + 32 把它换算为华氏度T。取到一位小数。
练习题(虚构数值,不作为临床指导)。 一次输注从 18:40 开始,到次日早晨 02:40 结束(24 小时制)。它运行了多少小时t?答案以小数表示小时数,取到两位小数。
一名体重 7 kg 的儿童按 15 mg/kg 处方用药。原液浓度为 25 mg/mL。请抽取剂量:应给多少体积 V?
一名体重 8 kg 的儿童,医嘱为口服混悬液每次 10 mg/kg,该混悬液每 5 mL 含 250 mg。你应给多少体积 V?
用滴系数为 20 滴/mL 的输液器在 5 小时内输入 500 mL。求滴速 R(滴/分)。 取整到最接近的整数。
一组输液以 28 滴/分的速度经 15 滴/mL 的输液器滴注。袋中还剩 450 mL。还需多少小时 t 才会滴完? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 一袋中含肝素 20 000 单位,容量 500 mL。医嘱为 18 units/kg/h,患者体重 53 kg。输液泵速率 R 应设为多少 mL/h? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 一名体重 98 kg 的患者的医嘱为norepinephrine 5 mcg/min。输液袋中含 4 mg,容量 250 mL。求泵速 R,以 mL/h 计。 保留一位小数。
练习题(虚构数值,不作为临床指导)。 记录显示了一名患者在一个 8 小时班次中的出入量。静脉输液在整个班次中按所示速率输注。求总入量 I,以 mL 计。
练习题(虚构数值,不作为临床指导)。 一份 500 mL 的输液于 16:00 开始以 100 mL/h 输注。4 小时后速率改为 60 mL/h,之后不再改变。从开始算起多少小时 t 后袋子会输完? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 用 Morse 跌倒评分评估一位练习患者:过去 3 个月内的跌倒史: 否; 次要诊断: 是; 行走辅助: 拐杖、手杖或助行器; 静脉输液或封管: 否; 步态: 受损; 精神状态: 高估或忘记自身局限。求 Morse 总分MFS。
练习题(虚构数值,不作为临床指导)。 对这些观察结果使用 NEWS2 图表(SpO₂ 量表 1):呼吸频率 18 次/分,SpO₂ 99%吸室内空气,血压 88/52 mmHg,脉搏 88 次/分,清醒,体温 39.2 °C。患者属于哪个临床风险组?点击它。
某练习动脉血气显示 pH 7.36,PaCO₂ 72 mmHg (9.6 kPa),HCO₃⁻ 39 mmol/L。原发性紊乱是呼吸性酸中毒。代偿到什么程度?点选你的答案。
某练习血气显示呼吸性酸中毒:pH 7.26,PaCO₂ 72 mmHg (9.6 kPa),HCO₃⁻ 31 mmol/L。利用规则“HCO₃⁻ 每 10 mmHg 升高 1 mmol/L(急性)或 3.5 mmol/L(慢性)”进行分类。点选你的答案。
解读这条 II 导联心律条带。这是什么节律?点击你的答案。
识别这条 II 导联心电图上的节律。点击你的答案。
答案: A · 氧气是一种药物,过多或过少都可能伤害患者
氧气被视为药物。目标范围指导护士调节流量,既避免低氧血症,也避免过量吸氧带来的伤害,例如对有 CO₂ 潴留的患者。
答案: A · Treat it as deterioration and escalate urgently
The score has dropped to about 13. Any new fall in consciousness or new confusion needs urgent escalation, a full ABCDE assessment and a check of glucose.
答案: A · An interferon-gamma release assay (IGRA) blood test
BCG vaccine can cause a false-positive tuberculin skin test. IGRA blood tests are not affected by BCG, so they are preferred for people who have had the vaccine.
答案: B · 松开该侧约束带并评估手部的血液循环
约束带远端出现循环不良的征象,需要立即松开并评估。只有在仍有必要时才正确重新系上,并用两指检查法确认,同时上报并记录发现。
答案: B · Relieve pressure on the area by changing position regularly
Non-blanching redness is a stage 1 pressure injury. Relieving pressure through repositioning and support surfaces is the priority; massage can damage tissue further.
答案: A · Level 2
Active suicidal ideation with a plan is a high-risk situation, so the patient is ESI level 2. They need prompt evaluation and a safe environment with close observation.
答案: D · 意识混乱、头痛和癫痫发作
低钠使水进入脑细胞,导致恶心、头痛、意识混乱,严重时癫痫发作。必须缓慢纠正,以避免渗透性脱髓鞘。
答案: D · "If I forget a dose, I'll take two the next day to catch up."
Doubling up on an anticoagulant increases the bleeding risk. Patients follow the specific missed-dose advice for their drug and never take a double dose.
答案: C · Possible recurrence that needs further assessment
CEA is not specific enough for screening, but a rising level after successful treatment can signal recurrence, so imaging and further assessment are usually arranged. Smoking and some benign conditions can also raise CEA.核对依据: CEA Test · MedlinePlus (NIH) (2026)
答案: C · Cloudy fluid, low glucose, high protein, many neutrophils
Bacterial meningitis typically gives cloudy CSF with many neutrophils, high protein and low glucose, because bacteria and white cells use glucose. Viral meningitis usually shows lymphocytes with a normal glucose; option C is normal CSF.核对依据: CSF glucose test · MedlinePlus (NIH) (2025); CSF cell count · MedlinePlus (NIH) (2025); CSF total protein · MedlinePlus (NIH) (2025)
答案: A · 单纯疱疹病毒和水痘-带状疱疹病毒等疱疹病毒
阿昔洛韦在受感染细胞中被病毒胸苷激酶磷酸化,随后阻断病毒 DNA 聚合酶。它用于唇疱疹、生殖器疱疹、水痘和带状疱疹。
答案: B · Low serum magnesium
Long-term PPI use can cause hypomagnesaemia, which leads to cramps, tremor and arrhythmias. Other long-term risks include fractures, vitamin B12 deficiency and C. difficile infection.
答案: D · 80 mmHg
MAP ≈ diastolic + (systolic − diastolic) ÷ 3 = 60 + 60 ÷ 3 = 80 mmHg. The heart spends longer in diastole, so MAP is closer to the diastolic value. A MAP of at least about 65 mmHg is a common target for organ perfusion.
答案: B · Urgent needle or finger decompression of the right chest
These signs indicate a tension pneumothorax, which causes obstructive shock. It is decompressed immediately (needle or finger thoracostomy) without waiting for an X-ray, followed by a chest drain. The nurse gives high-flow oxygen and calls for senior help.
答案: B · Glucose tablets or a small glass of fruit juice
About 15–20 g of fast-acting carbohydrate, such as glucose tablets or juice, raises glucose quickly. Chocolate and milk contain fat, which slows absorption. Glucose is rechecked after about 15 minutes.
答案: C · Low potassium increases the risk of digoxin toxicity
Digoxin binds to the sodium–potassium pump, and low potassium increases this binding. Hypokalaemia therefore raises the risk of toxicity and arrhythmias, even with a normal digoxin level. The potassium is corrected and the patient monitored.
答案: B · Soon after an acute soft tissue injury, to reduce swelling
Cold reduces swelling, bleeding and nerve conduction in acute injuries. It is wrapped and applied for short periods and avoided on areas with poor circulation or sensation. Heat is better for muscle spasm and stiffness.
答案: C · 27%
The whole arm is 9% and the front of the trunk 18%, giving 27% total body surface area. Superficial (redness only) areas would not be counted.
答案: C · 体重下降约为出生体重的 6%
最初几天体重下降最多约 7–10% 很常见,通常在约 10–14 天恢复出生体重。下降幅度更大或湿尿布过少时,需要评估喂养情况。
答案: A · Report reduced fetal movements straight away
Intrahepatic cholestasis is linked with stillbirth, especially with high bile acids. Women are monitored closely, told to report reduced movements and may be offered birth earlier. Cool baths and emollients ease itching.
答案: D · BMI plotted on an age- and sex-specific centile chart
In children, BMI is interpreted using age- and sex-specific centile charts, because normal BMI changes with growth. Adult cut-offs such as 25 and 30 do not apply to children.
答案: B · Respect beliefs where possible, explore alternatives and seek legal authority if needed
Clinicians work with families to respect beliefs and use alternatives where safe. When a child's life is at risk, many legal systems allow the team to seek a court order or act in an emergency to give necessary treatment.
答案: B · Keeping an emergency bag with documents, money and keys somewhere safe
A safety plan includes an escape bag, important documents, a safe place to go, emergency numbers and a code word with trusted people. The time of leaving can be the most dangerous period.
答案: A · Discuss the problem openly and involve patients in finding a solution
In a therapeutic milieu, the ward environment itself is used for treatment. Shared decision-making in community meetings builds responsibility, social skills and trust.
答案: T = 95.7 °F
温度:°C = (°F − 32) × 5/9,°F = °C × 9/5 + 32。从 °F 换算时先减 32 再乘,从 °C 换算时先乘再加 32。快速核对:37 °C 为 98.6 °F,每 1 °C 相当于 1.8 °F。
答案: t = 8 h
24 小时制:下午 1 点起,小时数加 12(下午 3:45 = 15:45)。午夜到凌晨 12:59 为 00:00–00:59,中午 12:00–12:59 仍为 12:00–12:59。反过来换算时,13–23 点减 12 并标为下午;00 点变为凌晨 12 点。跨午夜计算时间要分两段:先算到 24:00(00:00),再从 00:00 算起。
答案: V = 4.2 mL
抽取剂量:体积 = (处方剂量/药物浓度) × 药物体积。先换算成相同的单位,再检查该体积是否适合注射器,并落在它的某一个刻度上。
在这支 10 mL 的注射器上,每条小刻度线代表 0.2 mL。
答案: V = 1.6 mL
剂量计算:给药量等于医嘱剂量除以现有药物的规格,再乘以该规格对应的量:给药量 = (医嘱剂量/储备规格) × 储备体积。始终统一单位(先把 g 换成 mg,mg 换成 mcg),并检查答案是否合理。
答案: R = 33 gtt/min
输注速率:输液泵按 mL/h = 体积/时间(小时)设定。重力滴注按每分钟滴数计:gtt/min = 体积 (mL) × 滴系数 (gtt/mL)/时间 (min)。 滴系数印在输液器包装上:普通输液器为 10、15 或 20 gtt/mL(输血器在美国常为 10 gtt/mL,在英国为 15),微量输液器为 60 gtt/mL。务必使用题目或包装给出的滴系数。
床旁取最接近的整滴:33 滴/分。
答案: t = 4 h
输注速率:输液泵按 mL/h = 体积/时间(小时)设定。重力滴注按每分钟滴数计:gtt/min = 体积 (mL) × 滴系数 (gtt/mL)/时间 (min)。 滴系数印在输液器包装上:普通输液器为 10、15 或 20 gtt/mL(输血器在美国常为 10 gtt/mL,在英国为 15),微量输液器为 60 gtt/mL。务必使用题目或包装给出的滴系数。
答案: R = 23.9 mL/h
肝素和胰岛素输注:浓度 = 袋中单位数/袋容量 (units/mL)。泵速 (mL/h) = 每小时单位数/浓度,每小时单位数 = mL/h × 浓度。按体重给药时,先求 units/h = units/kg/h × 体重。推注体积 = 所需单位数/药瓶规格。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: R = 18.8 mL/h
滴定输注:先求以 mcg/mL 计的浓度(mg × 1000/mL)。按体重给药时,mcg/min = mcg/kg/min × 体重。然后 mL/h = mcg/min × 60/浓度。反推时,mcg/kg/min = mL/h × 浓度/(60 × 体重)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
医嘱是针对患者整体的每分钟剂量,所以不需要体重。
答案: I = 1470 mL
出入量:入量计入所有进入体内的液体(口服液体、静脉输液、静脉用药及冲管液、管饲);冰屑按其体积的一半计。出量计入尿液、引流液、呕吐物和其他丢失。平衡 = 总入量 − 总出量;平衡为负表示净丢失。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: t = 5.7 h
输液时间:时间 (h) = 待输体积 (mL)/速率 (mL/h);使用袋中剩余的体积,而不是袋的容量。已输入体积 = 速率 × 时间。把小数小时换算为小时和分钟时,用小数部分 × 60(0.5 h = 30 min,而不是 50 min)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
约为 5 h 40 min,所以袋子大约在 21:40 输完。
答案: MFS = 65
Morse 跌倒评分:六个条目。跌倒史:否 0 分,是 25 分。次要诊断:否 0 分,是 15 分。行走辅助:无、卧床休息或护士协助 0 分;拐杖、手杖或助行器 15 分;扶着家具 30 分。静脉输液或封管:否 0 分,是 20 分。步态:正常、卧床休息或轮椅 0 分;虚弱 10 分;受损 20 分。精神状态:了解自身局限 0 分;高估或忘记自身局限 15 分。总分为 0 至 125。各医院的风险分界值不同;常用的一套是 0–24 低风险,25–44 中度风险,45 及以上为高风险。
答案: 中
NEWS2(国家早期预警评分 2,英国皇家内科医师学会 2017):按图表为七个参数分别评分(呼吸频率、量表 1 的 SpO₂、吸空气还是吸氧、收缩压、脉搏、按 ACVPU 量表评定的意识状态和体温),然后把分数相加。临床风险:0–4 为低;任何单项参数得 3 分为中低;5–6 为中;7 或以上为高。总分 5 或以上需要紧急响应。
总分 5 或以上需要紧急的临床响应。
答案: 完全代偿
解读血气(ROME):先看 pH:低于 7.35 为酸血症,高于 7.45 为碱血症。然后找出能解释它的指标。PaCO₂(正常 35–45 mmHg,4.7–6.0 kPa)是呼吸方面的指标,在呼吸性紊乱中与 pH 反向(Opposite)变化;HCO₃⁻(正常 22–26 mmol/L)是代谢方面的指标,与 pH 同向变化(Respiratory Opposite, Metabolic Equal,即呼吸性相反,代谢性相同)。另一个指标显示代偿情况:正常表示未代偿;沿着使 pH 回升的方向异常、而 pH 仍然异常,表示部分代偿;pH 正常而两个指标都异常,表示完全代偿。各实验室的范围略有差异;这些是练习用数值。
答案: 慢性基础上的急性
预期代偿:代谢性酸中毒时,温特公式预测 PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg;实测值高于该范围提示合并呼吸性酸中毒,低于该范围提示合并呼吸性碱中毒。阴离子间隙 AG = Na⁺ − (Cl⁻ + HCO₃⁻),正常约为 8–12 mmol/L,用于区分高阴离子间隙与正常阴离子间隙代谢性酸中毒;低白蛋白会掩盖升高的间隙(白蛋白低于 4.0 的部分,每 g/dL 加 2.5)。Δ 比值 (AG − 12)/(24 − HCO₃⁻) 约在 0.8 到 2 之间符合单纯高间隙酸中毒(有些教材用 1 代替 0.8),低于此范围提示合并正常间隙酸中毒,高于 2 提示合并代谢性碱中毒。
答案: 心房颤动
节律标准(II 导联):窦性心律每个 QRS 之前都有直立的 P 波,PR 恒定为 0.12–0.20 s,QRS 狭窄:60–100 次/分为正常窦性心律,低于 60 为窦性心动过缓,高于 100 为窦性心动过速。心房颤动:无 P 波,基线呈颤动,R–R 绝对不规则。心房扑动:约 250–350 次/分的锯齿状扑动波,伴固定的传导比例,如 2:1 或 4:1。一度房室传导阻滞:窦性心律,PR 恒定且大于 0.20 s。交界性心律:窄 QRS,40–60 次/分,P 波缺失或倒置(PR 低于 0.12 s,或 P 波在 QRS 之后)。室性早搏(PVC)是提前出现的宽大(0.12 s 或以上)、形态怪异的 QRS,没有 P 波,T 波方向相反,通常有完全性代偿间歇;二联律是指每隔一个搏动就有一个室性早搏。
答案: 室性心动过速
室性节律:室性心动过速是连续三个或以上宽大(0.12 s 或以上)的波群,频率超过 100 次/分,通常为 150–250 次/分,节律规则,没有相关的 P 波。心室颤动是紊乱、不规则的波形,无法辨认 P 波、QRS 波群或 T 波,也没有可计数的频率。心脏停搏是几乎平直的线,没有心室活动;平直线一定要通过检查患者、导联和增益并换一个导联来确认。在复苏指南中,室颤和无脉性室速是可电击心律,心脏停搏则不是。
在复苏指南中,室颤和无脉性室速是可电击心律。这里只是识别练习。
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