感染控制与患者安全
方法
- 对每位患者都从标准预防开始:手卫生、针对预期暴露的个人防护装备、安全使用锐器。
- 按传播途径追加预防措施:接触传播(隔离衣、手套)、飞沫传播(外科口罩)、空气传播(N95、负压病房)。
- 保持无菌物品的无菌状态:如有疑问就视为不无菌;更换,绝不擦拭。
- 预防环境中的伤害:防跌倒措施,约束仅作为最后手段,火灾时用 RACE 和 PASS。
- 核对给药的正确原则、两个身份识别信息,以及对高警示药物的额外保障;报告差错和险兆事件。
公式表、每个专题的关键方法步骤和 40 道练习题,完整解答附在最后。
How should a patient walk with a standard (non-wheeled) walking frame?
一名患者 24 小时入量为 2400 mL,测得的总出量为 1800 mL。液体平衡是多少?
A patient has received oral radioactive iodine therapy. Which precaution is usually taken?
A nurse has a needlestick from a patient with hepatitis B. The nurse finished the vaccine series and has a documented protective antibody level. Which statement is correct?
Before accessing a central venous catheter, what should the nurse do to prevent infection?
A patient with diabetic ketoacidosis is about to start an IV insulin infusion. The serum potassium is 3.0 mEq/L. What should the nurse do?
A patient with DKA has an arterial blood gas showing a low pH and a low bicarbonate. Which disturbance is this?
A patient on an unfractionated heparin infusion is also started on warfarin. Which tests are used to monitor each drug?
The heparin infusion rate was changed according to protocol. When is the aPTT usually rechecked?
A patient with jaundice and nausea has a positive IgM antibody to hepatitis A virus (IgM anti-HAV). What does this show?
When should a patient take a once-daily proton pump inhibitor such as omeprazole?
A 19-year-old woman is starting isotretinoin for severe acne. Which requirement is most important?
根据现行指南,急性冠脉综合征患者何时应给氧?
After intubation, breath sounds are heard on the right side of the chest but not the left. What is the most likely cause?
A patient with atrial fibrillation has had an ischaemic stroke. Which long-term medicine type most reduces the risk of another stroke?
A nurse teaches foot care to a patient with diabetic neuropathy. Which statement shows a need for further teaching?
What are anticipatory ("just in case") medicines at the end of life usually prescribed for?
大面积烧伤后第 3 天,患者开始排出大量尿液。护士应预期哪种电解质问题?
Which position of the fetal head presents the smallest diameter to the pelvis?
A woman had a classical (vertical upper-segment) caesarean in her last pregnancy. She asks about her plan for this birth. Which answer is accurate?
Which instruction about using an adrenaline (epinephrine) auto-injector is correct?
一名囊性纤维化患儿排出量多、油腻、恶臭的大便,尽管食欲良好但体重不增。这最可能说明什么?
A patient on a mental health ward insists that he is a famous inventor whose ideas were stolen by the government. Which type of delusion is the main one here?
The daughter of a man with moderate dementia says she is exhausted, is not sleeping and feels guilty for getting angry with him. What is the most helpful nursing response?
练习题(虚构数值,不作为临床指导)。 一位患者身高 168 cm。按 1 in = 2.54 cm,求以英寸表示的身高h。取到一位小数。
练习题(虚构数值,不作为临床指导)。 一张处方写着口服混悬液½ tsp,每天四次,共 10 天。按1 tsp = 5 mL,整个疗程需要多少 mLV?
某患者体重 12 kg,医嘱为单次给药 15 mg/kg。求剂量 D(mg)。
一名体重 28 kg 的儿童,医嘱为口服混悬液每次 12.5 mg/kg,该混悬液每 5 mL 含 250 mg。你应给多少体积 V?
用滴系数为 10 滴/mL 的输液器在 4 小时内输入 1500 mL。求滴速 R(滴/分)。 取整到最接近的整数。
医嘱要求在 10 小时内输入 1000 mL。5 小时后你发现袋中还剩 620 mL,而输液仍须按时完成。 原来的泵速必须提高百分之多少 Δ?
练习题(虚构数值,不作为临床指导)。 一袋中含肝素 25 000 单位,容量 500 mL。医嘱为 12 units/kg/h,患者体重 90 kg。输液泵速率 R 应设为多少 mL/h? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 一袋中含dopamine 800 mg,容量 500 mL。医嘱为 5 mcg/kg/min,患者体重 97 kg。输液泵速率 R 应设为多少 mL/h? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 记录显示了一名患者在一个 12 小时班次中的出入量。患者体重 100 kg。求平均尿量 U,以 mL/kg/h 计。 保留两位小数。
练习题(虚构数值,不作为临床指导)。 一袋 1000 mL 的液体于 07:30 开始用输液泵以 150 mL/h 输注。到 13:30 时袋中还剩多少 mL V?
练习题(虚构数值,不作为临床指导)。 对这些观察结果使用 NEWS2 图表(SpO₂ 量表 1):呼吸频率 16 次/分,SpO₂ 99%正在补充吸氧,血压 136/82 mmHg,脉搏 70 次/分,清醒,体温 35.5 °C。NEWS2 总分是多少?
练习题(虚构数值,不作为临床指导)。 用 Morse 跌倒评分评估一位练习患者:过去 3 个月内的跌倒史: 否; 次要诊断: 否; 行走辅助: 无、卧床休息或由护士协助; 静脉输液或封管: 是; 步态: 正常、卧床休息或轮椅; 精神状态: 了解自身局限。使用分界值 0–24 低,25–44 中度,45 或以上高,点击跌倒风险等级。
某练习血气显示 PaCO₂ 27 mmHg (3.6 kPa)。利用规则:在急性呼吸性碱中毒中,PaCO₂ 每比 40 低出 10 mmHg,HCO₃⁻ 下降 2 mmol/L,以HCO₃⁻ 24 mmol/L 为起点,求预期HCO₃⁻。
某练习血气显示代谢性酸中毒:pH 7.19,PaCO₂ 46 mmHg (6.1 kPa),HCO₃⁻ 17 mmol/L。把实测的PaCO₂与温特公式比较。点选你的解读。
这条 II 导联心电图显示传导比例固定的心房扑动。求出心室率(单位:次/分)。
这位患者装有起搏器。请解读这条 II 导联心电图条带。点击你的答案。
答案: B · Lift the frame forward, then step into it
The frame is lifted a short step forward with all four feet placed down, then the patient steps into it, usually leading with the weaker leg.
答案: A · 正平衡 600 mL
2400 − 1800 = +600 mL,为正平衡。出汗和呼吸等不显性失水没有被测量,因此实际平衡低于记录单所显示的数值。
答案: C · Limit time close to the patient and handle body fluids per radiation policy
Radioactive iodine is excreted in urine, sweat and saliva, so the patient is usually in a private room with their own bathroom. Staff limit time near them, use distance and follow policy for body fluids and waste.
答案: D · No hepatitis B treatment is needed, but the injury is still reported and followed up
A documented vaccine responder is protected against hepatitis B and needs no hepatitis B prophylaxis. The exposure is still reported, because the nurse and source patient need assessment for HIV and hepatitis C as well.
答案: A · Scrub the hub with an antiseptic such as chlorhexidine and let it dry
Scrubbing the needleless connector with an antiseptic, such as chlorhexidine or alcohol, and letting it dry reduces central line infections. Aseptic technique is used for every access.
答案: C · Report the result before starting, because insulin will push potassium even lower
Insulin drives potassium into cells and can cause dangerous hypokalemia, so a low starting potassium must be reported. US (ADA) guidance delays insulin until potassium is at least 3.3 mEq/L; UK (JBDS) guidance asks for urgent senior review and potassium replacement. Either way, the prescriber decides.
答案: B · Metabolic acidosis
In DKA, ketoacids consume bicarbonate, causing a metabolic acidosis. The patient breathes deeply and fast (Kussmaul breathing) to lower PaCO2 as compensation.
答案: A · APTT for heparin and INR for warfarin
The APTT reflects the intrinsic pathway and is used to adjust heparin infusions. Warfarin is monitored by the INR, a standardised prothrombin time. Platelets are also checked on heparin to detect HIT.
答案: A · About 6 hours after the change
Most weight-based heparin protocols check the aPTT (or anti-Xa level) about 6 hours after starting or changing the rate, because it takes this long to reach a new steady state. Checking too early can lead to wrong adjustments.
答案: B · A current or recent hepatitis A infection
IgM antibodies appear early, so IgM anti-HAV indicates acute hepatitis A. IgG anti-HAV alone shows past infection or vaccination and lifelong immunity. Hepatitis A does not become chronic and spreads by the fecal-oral route, so hand hygiene is essential.核对依据: Hepatitis A · MedlinePlus (NIH) (2025)
答案: B · About 30–60 minutes before the first meal of the day
Proton pump inhibitors block pumps that are active, so they work best when taken before breakfast. Food then activates the pumps when the drug level is high.
答案: D · Reliable contraception and pregnancy tests, as it is highly teratogenic
Isotretinoin causes severe birth defects. Pregnancy prevention programmes require effective contraception and regular pregnancy tests before, during and after treatment.
答案: D · 仅当 SpO₂ 低于目标范围时
对没有低氧血症的患者常规给予高流量氧气没有益处,还可能增大梗死面积。当饱和度低于目标值(例如某些指南为低于 90%,另一些为低于 94%)时才给氧。
答案: A · The tube has entered the right main bronchus
The right main bronchus is more in line with the trachea, so a tube pushed too far usually enters it and only the right lung is ventilated. The tube is withdrawn slightly by the team and position is rechecked. Oesophageal intubation gives no breath sounds and gastric gurgling.
答案: A · An oral anticoagulant
In AF the main cause of stroke is a clot from the left atrium. Oral anticoagulants such as a DOAC or warfarin prevent this far better than antiplatelets. The start date after a stroke depends on its size and bleeding risk.
答案: B · "I will buy corn plasters from the pharmacy for my corn."
Medicated corn plasters contain acids that can burn the skin and cause ulcers in people with neuropathy or poor circulation. Corns and calluses should be treated by a podiatrist.
答案: B · Pain, nausea, agitation and respiratory secretions
Anticipatory medicines are prescribed in advance, usually for subcutaneous use, so that common end-of-life symptoms can be treated quickly without delay, especially at home.
答案: C · 低钾血症,因为液体回到循环中
在最初几小时,细胞破坏和液体转移可使钾升高。约 48–72 小时后,毛细血管完整性改善,液体回到循环,开始利尿,伴钾丢失和低钾血症。全程应监测电解质。
答案: D · Full flexion, with the chin on the chest
When the head is fully flexed, the suboccipitobregmatic diameter of about 9.5 cm presents. Extension, as in brow and face presentations, presents larger diameters and can obstruct labour.
答案: A · A planned repeat caesarean before labour is advised
A classical uterine scar carries a high risk of rupture during labour, so trial of labour is contraindicated. A repeat caesarean is planned before labour starts, and she should come in at once if contractions begin.
答案: C · Inject into the outer thigh, through clothing if needed, and call emergency services
Auto-injectors are given into the outer mid-thigh and can go through clothing. Emergency services are called after every use, as symptoms can recur, and a second dose may be needed.
答案: B · 脂肪吸收不良;需要复查胰酶的剂量或服用时间
脂肪泻和生长不良提示吸收不良。团队应复查酶的剂量、与进餐的时间配合以及依从性。囊性纤维化患儿通常需要高热量、高脂肪的饮食。
答案: C · Grandiose
Grandiose delusions are false beliefs about one's own importance, power or identity. They may combine with persecutory themes, as here, but the central belief is about being exceptional.
答案: C · Acknowledge her strain and discuss support such as respite care and carers' groups
Caregiver strain is common and can affect both the carer and the patient. Recognising it, and offering respite, practical support and carers' groups, helps the carer continue safely.
答案: h = 66.1 in
家用计量和体重:护理考试使用取整的等量关系:1 茶匙(tsp)= 5 mL,1 汤匙(tbsp)= 15 mL = 3 tsp,1 液量盎司(fl oz)= 30 mL = 2 tbsp,1 杯 = 8 fl oz = 240 mL。体重方面,1 kg = 2.2 lb,1 lb = 16 oz;长度方面,1 英寸 = 2.54 cm。设置换算时,要让你不需要的单位相互约去。
答案: V = 100 mL
量纲分析:先写出已知量,再乘以写成分数形式的换算系数(例如 60 min/1 h 或 1 mg/1000 mcg),使每个不需要的单位在分子和分母各出现一次并相互约去。只剩下所求单位时再计算。使用题目给出的等量关系,只对最终答案取整。
答案: D = 180 mg
剂量计算:给药量等于医嘱剂量除以现有药物的规格,再乘以该规格对应的量:给药量 = (医嘱剂量/储备规格) × 储备体积。始终统一单位(先把 g 换成 mg,mg 换成 mcg),并检查答案是否合理。
答案: V = 7 mL
剂量计算:给药量等于医嘱剂量除以现有药物的规格,再乘以该规格对应的量:给药量 = (医嘱剂量/储备规格) × 储备体积。始终统一单位(先把 g 换成 mg,mg 换成 mcg),并检查答案是否合理。
答案: R = 63 gtt/min
输注速率:输液泵按 mL/h = 体积/时间(小时)设定。重力滴注按每分钟滴数计:gtt/min = 体积 (mL) × 滴系数 (gtt/mL)/时间 (min)。 滴系数印在输液器包装上:普通输液器为 10、15 或 20 gtt/mL(输血器在美国常为 10 gtt/mL,在英国为 15),微量输液器为 60 gtt/mL。务必使用题目或包装给出的滴系数。
床旁取最接近的整滴:63 滴/分。
答案: Δ = 24 %
Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.
许多医院允许在不重开医嘱的情况下进行不超过 25% 的此类调整;请查阅本院规定。
答案: R = 21.6 mL/h
肝素和胰岛素输注:浓度 = 袋中单位数/袋容量 (units/mL)。泵速 (mL/h) = 每小时单位数/浓度,每小时单位数 = mL/h × 浓度。按体重给药时,先求 units/h = units/kg/h × 体重。推注体积 = 所需单位数/药瓶规格。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: R = 18.2 mL/h
滴定输注:先求以 mcg/mL 计的浓度(mg × 1000/mL)。按体重给药时,mcg/min = mcg/kg/min × 体重。然后 mL/h = mcg/min × 60/浓度。反推时,mcg/kg/min = mL/h × 浓度/(60 × 体重)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: U = 0.56 mL/kg/h
出入量:入量计入所有进入体内的液体(口服液体、静脉输液、静脉用药及冲管液、管饲);冰屑按其体积的一半计。出量计入尿液、引流液、呕吐物和其他丢失。平衡 = 总入量 − 总出量;平衡为负表示净丢失。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: V = 100 mL
输液时间:时间 (h) = 待输体积 (mL)/速率 (mL/h);使用袋中剩余的体积,而不是袋的容量。已输入体积 = 速率 × 时间。把小数小时换算为小时和分钟时,用小数部分 × 60(0.5 h = 30 min,而不是 50 min)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: NEWS2 = 3
NEWS2(国家早期预警评分 2,英国皇家内科医师学会 2017):按图表为七个参数分别评分(呼吸频率、量表 1 的 SpO₂、吸空气还是吸氧、收缩压、脉搏、按 ACVPU 量表评定的意识状态和体温),然后把分数相加。临床风险:0–4 为低;任何单项参数得 3 分为中低;5–6 为中;7 或以上为高。总分 5 或以上需要紧急响应。
答案: 低风险
Morse 跌倒评分:六个条目。跌倒史:否 0 分,是 25 分。次要诊断:否 0 分,是 15 分。行走辅助:无、卧床休息或护士协助 0 分;拐杖、手杖或助行器 15 分;扶着家具 30 分。静脉输液或封管:否 0 分,是 20 分。步态:正常、卧床休息或轮椅 0 分;虚弱 10 分;受损 20 分。精神状态:了解自身局限 0 分;高估或忘记自身局限 15 分。总分为 0 至 125。各医院的风险分界值不同;常用的一套是 0–24 低风险,25–44 中度风险,45 及以上为高风险。
答案: HCO₃⁻ = 21.4 mmol/L
预期代偿:代谢性酸中毒时,温特公式预测 PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg;实测值高于该范围提示合并呼吸性酸中毒,低于该范围提示合并呼吸性碱中毒。阴离子间隙 AG = Na⁺ − (Cl⁻ + HCO₃⁻),正常约为 8–12 mmol/L,用于区分高阴离子间隙与正常阴离子间隙代谢性酸中毒;低白蛋白会掩盖升高的间隙(白蛋白低于 4.0 的部分,每 g/dL 加 2.5)。Δ 比值 (AG − 12)/(24 − HCO₃⁻) 约在 0.8 到 2 之间符合单纯高间隙酸中毒(有些教材用 1 代替 0.8),低于此范围提示合并正常间隙酸中毒,高于 2 提示合并代谢性碱中毒。
答案: 合并呼吸性酸中毒
预期代偿:代谢性酸中毒时,温特公式预测 PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg;实测值高于该范围提示合并呼吸性酸中毒,低于该范围提示合并呼吸性碱中毒。阴离子间隙 AG = Na⁺ − (Cl⁻ + HCO₃⁻),正常约为 8–12 mmol/L,用于区分高阴离子间隙与正常阴离子间隙代谢性酸中毒;低白蛋白会掩盖升高的间隙(白蛋白低于 4.0 的部分,每 g/dL 加 2.5)。Δ 比值 (AG − 12)/(24 − HCO₃⁻) 约在 0.8 到 2 之间符合单纯高间隙酸中毒(有些教材用 1 代替 0.8),低于此范围提示合并正常间隙酸中毒,高于 2 提示合并代谢性碱中毒。
答案: 心室率 = 100 bpm
节律标准(II 导联):窦性心律每个 QRS 之前都有直立的 P 波,PR 恒定为 0.12–0.20 s,QRS 狭窄:60–100 次/分为正常窦性心律,低于 60 为窦性心动过缓,高于 100 为窦性心动过速。心房颤动:无 P 波,基线呈颤动,R–R 绝对不规则。心房扑动:约 250–350 次/分的锯齿状扑动波,伴固定的传导比例,如 2:1 或 4:1。一度房室传导阻滞:窦性心律,PR 恒定且大于 0.20 s。交界性心律:窄 QRS,40–60 次/分,P 波缺失或倒置(PR 低于 0.12 s,或 P 波在 QRS 之后)。室性早搏(PVC)是提前出现的宽大(0.12 s 或以上)、形态怪异的 QRS,没有 P 波,T 波方向相反,通常有完全性代偿间歇;二联律是指每隔一个搏动就有一个室性早搏。
答案: 起搏心律,夺获失败
起搏心律:起搏器脉冲表现为一条细而垂直的起搏钉样信号。心室钉样信号之后的 QRS 是增宽的(0.12 s 或以上),因为冲动是从导线经心肌传播,而不是经传导系统;右心室起搏时,在 II 导联上通常以负向为主。P 波之前的钉样信号表示心房起搏;双腔(房室)起搏器则表现为心房钉样信号加 P 波,再经过程控的房室延迟,出现心室钉样信号和增宽的 QRS。夺获是指每个钉样信号之后都跟着一次除极。夺获失败是指钉样信号之后没有 P 波或 QRS;感知不良(钉样信号无视患者自己的心搏)和起搏不良(该出现钉样信号时没有)是另外两种典型的故障。
夺获失败:起搏器发放了脉冲,但心脏没有反应。教科书把它视为需要紧急报告的情况,因为患者可能依赖起搏器。
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