感染控制与患者安全
方法
- 对每位患者都从标准预防开始:手卫生、针对预期暴露的个人防护装备、安全使用锐器。
- 按传播途径追加预防措施:接触传播(隔离衣、手套)、飞沫传播(外科口罩)、空气传播(N95、负压病房)。
- 保持无菌物品的无菌状态:如有疑问就视为不无菌;更换,绝不擦拭。
- 预防环境中的伤害:防跌倒措施,约束仅作为最后手段,火灾时用 RACE 和 PASS。
- 核对给药的正确原则、两个身份识别信息,以及对高警示药物的额外保障;报告差错和险兆事件。
公式表、每个专题的关键方法步骤和 40 道练习题,完整解答附在最后。
A patient arrives back on the ward after surgery. What does the nurse assess first?
According to the gate control theory, why can rubbing a bumped elbow ease the pain?
A patient is on a ventilator. Which bed position helps to prevent ventilator-associated pneumonia?
入院时,患者的居家用药清单中有一种抗凝药,没有出现在新的住院医嘱中。护士应怎么做?
A patient has a tonic-clonic seizure in bed. What should the nurse do first?
An adult has burns over 40% of the body with no signs of airway injury. Which treatment is the priority during the first hours?
骨折腿部打石膏后,哪项评估最能发现骨筋膜室综合征?
Which patient should the nurse assess first?
A patient taking empagliflozin (an SGLT2 inhibitor) has glucose in the urine but a normal blood glucose. What is the best interpretation?
A patient with a large, fast-growing lymphoma will start chemotherapy tomorrow. Which plan best prevents tumor lysis syndrome?
Which group of signs suggests opioid withdrawal?
Morphine 4 mg IV is ordered. The ampoule contains 10 mg/mL. What volume should be drawn up?
When should an adult with cystic fibrosis take pancreatic enzyme capsules?
The stump of a recent below-knee amputation suddenly bleeds heavily through the dressing. What should the nurse do first?
Where is the zero point of an external ventricular drain usually levelled?
一名因颈椎骨折佩戴 halo 背心的患者发生心脏骤停。必须立即备好什么?
Which change suggests that a burn wound is becoming infected?
A nurse finds a dislodged sealed radiation source in the bed of a patient receiving brachytherapy. What should the nurse do?
卡前列素是一种用于产后出血的前列腺素,应避免用于:
A nurse is teaching a mother how to prevent shaken baby syndrome. Which statement shows a need for further teaching?
一名儿童在咽痛两周后出现可乐色尿、眼睑浮肿和高血压。可能的诊断是什么?
一名 6 岁的镰状细胞病患儿体温 39.0 °C。为什么要作为紧急情况处理?
A patient who drinks heavily every day was admitted this morning. When do early signs of alcohol withdrawal, such as tremor, sweating and anxiety, usually begin?
一名患者被发现无反应,呼吸频率 6 次/分,瞳孔针尖样。护士应首先做什么?
练习题(虚构数值,不作为临床指导)。 一次小剂量注射的计算得到 0.75415 mL。 本练习的规则是:低于 1 mL 的体积取到最接近的百分之一 mL。你记录的数值x是多少?
练习题(虚构数值,不作为临床指导)。 血糖结果为 179 mg/dL。按葡萄糖 1 mmol/L = 18 mg/dL,求以 mmol/L 表示的c。取到一位小数。
一名体重 52 kg 的患者体表面积为 1.41 m²。医嘱为 75 mg/m²。求剂量 D,以 mg 表示。
一名患者体重 114.4 lb。医嘱为单次剂量 5 mg/kg,储备液为 5 mL 中含 200 mg。按 1 kg = 2.2 lb 计算,你应给予多少容量 V?
用滴系数为 20 滴/mL 的输液器在 12 小时内输入 1500 mL。求滴速 R(滴/分)。 取整到最接近的整数。
将 200 mg 药物稀释于 100 mL 中,通过滴系数为 15 gtt/mL 的输液器重力滴注。医嘱为每小时 80 mg。求滴速 R,以每分钟滴数表示。
练习题(虚构数值,不作为临床指导)。 一袋中含肝素 25 000 单位,容量 500 mL。医嘱为 15 units/kg/h,患者体重 52 kg。输液泵速率 R 应设为多少 mL/h? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 一袋中含dopamine 400 mg,容量 250 mL。医嘱为 2 mcg/kg/min,患者体重 82 kg。输液泵速率 R 应设为多少 mL/h? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 记录显示了一名患者在一个 12 小时班次中的出入量。患者体重 99 kg。求平均尿量 U,以 mL/kg/h 计。 保留两位小数。
练习题(虚构数值,不作为临床指导)。 一份 1000 mL 的输液于 06:30 开始以 80 mL/h 输注。2 小时后速率改为 50 mL/h,之后不再改变。从开始算起多少小时 t 后袋子会输完? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 用 Morse 跌倒评分评估一位练习患者:过去 3 个月内的跌倒史: 是; 次要诊断: 是; 行走辅助: 扶着家具; 静脉输液或封管: 是; 步态: 虚弱; 精神状态: 高估或忘记自身局限。求 Morse 总分MFS。
练习题(虚构数值,不作为临床指导)。 一名成人体重 72 kg,身高 158 cm。计算 BMI 并点击 WHO 体重分类。
某练习动脉血气显示 pH 7.30,PaCO₂ 40 mmHg (5.3 kPa),HCO₃⁻ 19 mmol/L。原发性紊乱是代谢性酸中毒。代偿到什么程度?点选你的答案。
在海平面,某练习血气取自吸入 24% 氧气时,显示 PaO₂ 65 mmHg (8.7 kPa),PaCO₂ 55 mmHg (7.3 kPa)。用 PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 求A–a 梯度。
解读这条 II 导联心律条带。这是什么节律?点击你的答案。
依次按五个步骤解读这条 II 导联心电图:心率、节律、P 波、PR 间期、QRS 时限。你在哪一步发现第一个异常?点击它。
答案: D · Airway and breathing
After anaesthesia the airway and breathing are checked first, then circulation, consciousness, pain, the wound, drains and fluids.
答案: C · Touch signals reduce pain signals passing up the spinal cord
The gate control theory proposes that input from touch fibres "closes the gate" in the dorsal horn of the spinal cord, reducing pain transmission. This underlies massage and TENS.
答案: B · Head of the bed raised 30 to 45 degrees
Raising the head of the bed to 30–45 degrees reduces aspiration of oral and gastric secretions into the lungs. It is part of the usual ventilator care bundle, unless contraindicated.
答案: B · 与开医嘱者澄清这一不一致
居家用药与住院医嘱之间无法解释的差异,可能是遗漏,也可能是有意更改。护士应询问开医嘱者,使决定明确并有记录。无意中遗漏抗凝药可能导致血栓。
答案: B · Protect the head and turn the patient on their side when possible
During a seizure the nurse protects the patient from injury and turns them to the side to keep the airway clear. Nothing is put in the mouth, movements are not restrained and nothing is given by mouth.
答案: A · Large-volume IV fluids with close monitoring of urine output
Once the airway is secure, the early priority in major burns is fluid resuscitation to prevent burn shock. Urine output is a key guide to whether enough fluid is being given.
答案: A · 疼痛与损伤程度不相称,尤其是被动牵拉时
镇痛无效且被动牵拉时加重的进行性疼痛是最早的征象。苍白、麻木和脉搏消失是晚期征象。
答案: B · A patient with asthma who can only speak in single words
Being unable to complete sentences is a sign of acute severe or life-threatening asthma, an airway and breathing emergency. The other patients need attention but are not immediately life-threatened.
答案: D · An expected effect of the drug
SGLT2 inhibitors block glucose reabsorption in the proximal tubule, so glycosuria is expected even with normal blood glucose. Urine glucose cannot be used to monitor control in these patients. The drugs also raise the risk of genital infections and DKA.核对依据: Ketones blood test · MedlinePlus (NIH) (2025)
答案: B · IV hydration, a uric acid-lowering drug and frequent electrolytes
Prevention includes aggressive IV hydration, drugs such as allopurinol or rasburicase to lower uric acid, and frequent monitoring of potassium, phosphate, calcium, uric acid and creatinine. Tumor lysis usually begins within 1–3 days of starting treatment.核对依据: Uric Acid Test · MedlinePlus (NIH) (2026)
答案: D · Yawning, runny nose, sweating, dilated pupils and diarrhoea
Opioid withdrawal causes rhinorrhoea, lacrimation, yawning, sweating, mydriasis, cramps, diarrhoea and anxiety. It is very unpleasant but rarely life-threatening in healthy adults.
答案: C · 0.4 mL
4 mg ÷ 10 mg/mL = 0.4 mL. The unused remainder of a controlled drug is discarded with a witness.
答案: D · With all meals and snacks that contain fat
In CF, thick secretions block the pancreatic ducts, causing fat malabsorption and fatty stools. Enzyme capsules are taken with every meal and fat-containing snack, with the dose adjusted to fat intake. Fat-soluble vitamins (A, D, E, K) are also supplemented.
答案: A · Apply firm direct pressure and call for urgent surgical help
Haemorrhage from a stump needs immediate direct pressure, elevation if appropriate, and urgent surgical help. A tourniquet should be available as policy directs. Vital signs are monitored for shock.
答案: A · At the tragus of the ear
The EVD is levelled at the tragus, which approximates the foramen of Monro. If the head of the bed is changed, the drain must be re-levelled, because its height decides how much CSF drains.
答案: A · 用于打开背心前部以便进行心肺复苏的工具
用于松开背心前部的工具应一直固定在背心上,以便在心肺复苏或气道管理时迅速打开。针孔部位需要定期护理以防感染,并需要教导患者背心下的皮肤护理。
答案: D · A partial-thickness burn becoming deeper, with new discolouration
Signs of burn wound infection include conversion to a deeper burn, new dark or green discolouration, increasing pain, offensive exudate, spreading redness and systemic signs such as fever or tachycardia.
答案: D · Use long-handled forceps to put it in the lead container; report it
A dislodged source is picked up with long-handled forceps and placed in the shielded container kept in the room. The radiation safety officer and team are informed, following local policy.
答案: B · 哮喘患者
卡前列素可引起支气管痉挛,因此哮喘患者应避免使用。高血压患者应避免的子宫收缩剂是甲麦角新碱。
答案: B · "If I feel very angry, it is fine to shake him a little to stop the crying."
Shaking a baby can cause brain injury, retinal haemorrhages and death. Parents are taught that crying is normal, to put the baby down safely and step away when frustrated, and to ask for help.
答案: B · 急性链球菌感染后肾小球肾炎
链球菌感染后肾小球肾炎出现在咽部感染后约 1–3 周(皮肤感染后则更晚),引起血尿、水肿和高血压。需监测血压、液体平衡和体重。
答案: D · 镰状细胞病患儿脾功能减退,发生严重细菌感染的风险很高
反复梗死使脾脏在儿童早期受损(功能性无脾),因此有荚膜的细菌可导致暴发性脓毒症。发热需要紧急评估,通常需要使用抗生素。
答案: C · About 6–24 hours after the last drink
Minor withdrawal symptoms begin within hours, usually 6–24 hours after the last drink. Seizures are most likely in the first 1–2 days, and delirium tremens usually appears later, around 2–3 days.
答案: D · 呼救,开放气道并支持呼吸,并按处方或规程给予纳洛酮
首先是气道和呼吸支持,并给予纳洛酮以逆转阿片类药物的作用。由于纳洛酮的作用可能先于阿片类药物消退,需密切监测患者。
答案: x = 0.75 mL
取整:看舍入位后面的那个数字:5 或更大则进位,4 或更小则保持原数字不变。只对最终答案取整,绝不对中间步骤取整。典型的考试规则:1 mL 或以上的体积取到十分位,低于 1 mL 的体积取到百分位,滴速取整到整滴,体重取到一位小数;务必遵循题目所规定的规则。
答案: c = 9.9 mmol/L
量纲分析:先写出已知量,再乘以写成分数形式的换算系数(例如 60 min/1 h 或 1 mg/1000 mcg),使每个不需要的单位在分子和分母各出现一次并相互约去。只剩下所求单位时再计算。使用题目给出的等量关系,只对最终答案取整。
答案: D = 105.8 mg
Body-surface-area dosing: many cytotoxic and some paediatric doses are prescribed per square metre of body surface area: dose (mg) = dose per m² × BSA (m²). The Mosteller formula estimates BSA = √(height (cm) × weight (kg)/3600).
答案: V = 6.5 mL
Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.
答案: R = 42 gtt/min
输注速率:输液泵按 mL/h = 体积/时间(小时)设定。重力滴注按每分钟滴数计:gtt/min = 体积 (mL) × 滴系数 (gtt/mL)/时间 (min)。 滴系数印在输液器包装上:普通输液器为 10、15 或 20 gtt/mL(输血器在美国常为 10 gtt/mL,在英国为 15),微量输液器为 60 gtt/mL。务必使用题目或包装给出的滴系数。
床旁取最接近的整滴:42 滴/分。
答案: R = 10 gtt/min
Dose-based infusions: concentration = amount of drug in the bag/bag volume. Pump rate (mL/h) = dose per hour/concentration, and dose per hour = mL/h × concentration. Convert per-minute doses to per-hour (× 60) and keep the mass units the same (1 g = 1000 mg, 1 mg = 1000 mcg).
答案: R = 15.6 mL/h
肝素和胰岛素输注:浓度 = 袋中单位数/袋容量 (units/mL)。泵速 (mL/h) = 每小时单位数/浓度,每小时单位数 = mL/h × 浓度。按体重给药时,先求 units/h = units/kg/h × 体重。推注体积 = 所需单位数/药瓶规格。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: R = 6.2 mL/h
滴定输注:先求以 mcg/mL 计的浓度(mg × 1000/mL)。按体重给药时,mcg/min = mcg/kg/min × 体重。然后 mL/h = mcg/min × 60/浓度。反推时,mcg/kg/min = mL/h × 浓度/(60 × 体重)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: U = 0.95 mL/kg/h
出入量:入量计入所有进入体内的液体(口服液体、静脉输液、静脉用药及冲管液、管饲);冰屑按其体积的一半计。出量计入尿液、引流液、呕吐物和其他丢失。平衡 = 总入量 − 总出量;平衡为负表示净丢失。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: t = 18.8 h
输液时间:时间 (h) = 待输体积 (mL)/速率 (mL/h);使用袋中剩余的体积,而不是袋的容量。已输入体积 = 速率 × 时间。把小数小时换算为小时和分钟时,用小数部分 × 60(0.5 h = 30 min,而不是 50 min)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
约为 18 h 48 min,所以袋子大约在 01:18 输完。
答案: MFS = 115
Morse 跌倒评分:六个条目。跌倒史:否 0 分,是 25 分。次要诊断:否 0 分,是 15 分。行走辅助:无、卧床休息或护士协助 0 分;拐杖、手杖或助行器 15 分;扶着家具 30 分。静脉输液或封管:否 0 分,是 20 分。步态:正常、卧床休息或轮椅 0 分;虚弱 10 分;受损 20 分。精神状态:了解自身局限 0 分;高估或忘记自身局限 15 分。总分为 0 至 125。各医院的风险分界值不同;常用的一套是 0–24 低风险,25–44 中度风险,45 及以上为高风险。
答案: 超重
体质指数:BMI = 体重(kg)/身高(m)²,身高要先换算为米。使用磅和英寸时,BMI = 703 × 体重(lb)/身高(in)²。WHO 成人分类:低于 18.5 为体重过轻,18.5–24.9 为健康体重,25.0–29.9 为超重,30.0–34.9 为肥胖 I 级,35.0–39.9 为肥胖 II 级,40 及以上为肥胖 III 级。
答案: 未代偿
解读血气(ROME):先看 pH:低于 7.35 为酸血症,高于 7.45 为碱血症。然后找出能解释它的指标。PaCO₂(正常 35–45 mmHg,4.7–6.0 kPa)是呼吸方面的指标,在呼吸性紊乱中与 pH 反向(Opposite)变化;HCO₃⁻(正常 22–26 mmol/L)是代谢方面的指标,与 pH 同向变化(Respiratory Opposite, Metabolic Equal,即呼吸性相反,代谢性相同)。另一个指标显示代偿情况:正常表示未代偿;沿着使 pH 回升的方向异常、而 pH 仍然异常,表示部分代偿;pH 正常而两个指标都异常,表示完全代偿。各实验室的范围略有差异;这些是练习用数值。
临床上还应检查预期代偿:按温特公式,预期 PaCO₂ 为 34.5–38.5 mmHg,所以实测 40 mmHg 提示合并呼吸性酸中毒(混合性紊乱)。上面的答案是按 ROME 法的考试分类。
答案: A–a 梯度 = 37.37 mmHg
衍生数值:计算所得的血清渗透压为 2·Na⁺ + 葡萄糖 + 尿素,各值均以 mmol/L 计(葡萄糖和 BUN 以 mg/dL 计时为 2·Na⁺ + 葡萄糖/18 + BUN/2.8);正常约为 275–295 mOsm/kg。P/F 比值是 PaO₂ 除以以小数表示的 FiO₂。海平面的肺泡氧分压为 PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg,A–a 梯度为 PAO₂ − PaO₂。
答案: 心房颤动
节律标准(II 导联):窦性心律每个 QRS 之前都有直立的 P 波,PR 恒定为 0.12–0.20 s,QRS 狭窄:60–100 次/分为正常窦性心律,低于 60 为窦性心动过缓,高于 100 为窦性心动过速。心房颤动:无 P 波,基线呈颤动,R–R 绝对不规则。心房扑动:约 250–350 次/分的锯齿状扑动波,伴固定的传导比例,如 2:1 或 4:1。一度房室传导阻滞:窦性心律,PR 恒定且大于 0.20 s。交界性心律:窄 QRS,40–60 次/分,P 波缺失或倒置(PR 低于 0.12 s,或 P 波在 QRS 之后)。室性早搏(PVC)是提前出现的宽大(0.12 s 或以上)、形态怪异的 QRS,没有 P 波,T 波方向相反,通常有完全性代偿间歇;二联律是指每隔一个搏动就有一个室性早搏。
答案: 节律
每条心电图的五个步骤:1. 心率(300 法或 1500 法;若不规则则用 6 秒法);2. 节律:R–R 间期是否相等;3. P 波:是否存在、在 II 导联直立、每个 QRS 之前各有一个且形态一致;4. PR 间期:0.12–0.20 s 且恒定;5. QRS 时限:低于 0.12 s。五个步骤做完之后才命名节律。正常窦性心律五项全部符合:60–100 次/分,规则,每个 QRS 之前有直立 P 波,PR 0.12–0.20 s,QRS 低于 0.12 s。
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