感染控制与患者安全
方法
- 对每位患者都从标准预防开始:手卫生、针对预期暴露的个人防护装备、安全使用锐器。
- 按传播途径追加预防措施:接触传播(隔离衣、手套)、飞沫传播(外科口罩)、空气传播(N95、负压病房)。
- 保持无菌物品的无菌状态:如有疑问就视为不无菌;更换,绝不擦拭。
- 预防环境中的伤害:防跌倒措施,约束仅作为最后手段,火灾时用 RACE 和 PASS。
- 核对给药的正确原则、两个身份识别信息,以及对高警示药物的额外保障;报告差错和险兆事件。
公式表、每个专题的关键方法步骤和 40 道练习题,完整解答附在最后。
How should a rectal suppository be inserted?
A patient has been taught breathing exercises before surgery. Which statement shows a need for further teaching?
A patient has received oral radioactive iodine therapy. Which precaution is usually taken?
A hospital will introduce new infusion pumps and wants to find out how the process could fail before any harm occurs. Which method fits best?
RN 将哪项任务委派给 LPN/LVN 最为恰当?
A patient has central chest pain that started 30 minutes ago at rest and has not eased with rest or nitroglycerin. What does this suggest?
一名意识不清的糖尿病患者血糖为 2.1 mmol/L,且没有静脉通路。可以给予什么?
A seriously ill patient asks the nurse, "Am I dying?" What is the best initial response?
一名患者接受皮下注射依诺肝素(一种低分子量肝素)。关于监测,哪项说法是正确的?
The nurse teaches a patient who is collecting a 24-hour urine sample at home. Which statement shows a need for further teaching?
肝素如何产生抗凝作用?
A patient on long-term prednisolone has been vomiting for two days and could not take her tablets. She is now hypotensive and confused, with low sodium and high potassium. What is the most urgent treatment?
How is the jugular venous pressure usually assessed?
经桡动脉心导管检查术后,最重要的评估是什么?
A bladder scan straight after voiding shows 450 mL of urine still in the bladder. What does this show?
一名使用呼吸机的患者有创伤性脑损伤。除非即将发生脑疝,通常的 PaCO₂ 目标是什么?
Why are laxatives and enemas avoided when appendicitis is suspected?
A 76-year-old with a past peptic ulcer needs long-term anti-inflammatory treatment for arthritis. Which plan best reduces GI bleeding risk?
Which finding in a term newborn's first hours is normal?
Women with pre-eclampsia can develop complications after birth. Which statement in discharge teaching is correct?
Using the 100–50–20 rule, what is the daily maintenance fluid requirement for a 15 kg child?
A 2-year-old has swallowed several of his mother's iron tablets. Why is this treated as an emergency even if he looks well?
A patient who drinks heavily every day was admitted this morning. When do early signs of alcohol withdrawal, such as tremor, sweating and anxiety, usually begin?
开始使用氟哌啶醇五天后,一名患者体温 40 °C,四肢强直,意识模糊,血压波动并出汗。护士应首先做什么?
练习题(虚构数值,不作为临床指导)。 一个剂量记录在 6:20 AM。哪个条目是 24 小时制中的同一时间?点击它。
练习题(虚构数值,不作为临床指导)。 一张处方写着口服混悬液1 tsp,每天三次,共 7 天。混悬液每瓶 150 mL。按1 tsp = 5 mL,必须提供多少整瓶N才能完成疗程?
一个药瓶中含有 2 g 的粉末。标签上写着:加入 7.4 mL 注射用水,得到总容量 8 mL。医嘱为 250 mg。你应给予复溶后溶液的多少容量 V?
一名患者体重 132 lb。医嘱为单次剂量 2 mg/kg,储备液为 1 mL 中含 50 mg。按 1 kg = 2.2 lb 计算,你应给予多少容量 V?
医嘱要求以 125 mL/h 输液,但没有输液泵。改用滴系数为 60 gtt/mL 的输液器重力滴注。求滴速 R,以每分钟滴数表示。
将 1000 mg 药物稀释于 500 mL 中,通过滴系数为 60 gtt/mL 的输液器重力滴注。医嘱为每小时 80 mg。求滴速 R,以每分钟滴数表示。
练习题(虚构数值,不作为临床指导)。 一项练习规程要求为体重 62 kg 的患者推注肝素 60 units/kg。药瓶规格为 1 000 units/mL。应抽取多少体积 V? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 一名体重 77 kg 的患者的医嘱为nitroglycerin 5 mcg/min。输液袋中含 25 mg,容量 250 mL。求泵速 R,以 mL/h 计。 保留一位小数。
练习题(虚构数值,不作为临床指导)。 记录显示了一名患者在一个 8 小时班次中的出入量。静脉输液在整个班次中按所示速率输注。求液体平衡 B = 入量 − 出量,以 mL 计(答案为负表示净丢失)。
练习题(虚构数值,不作为临床指导)。 一袋 1000 mL 的液体于 08:00 开始用输液泵以 80 mL/h 输注。到 13:30 时袋中还剩多少 mL V?
练习题(虚构数值,不作为临床指导)。 用 Braden 量表评估一位练习患者:感觉知觉: 完全受限; 潮湿程度: 偶尔潮湿; 活动: 卧床不起; 活动能力: 非常受限; 营养: 充足; 摩擦力和剪切力: 无明显问题。求 Braden 总分B。
练习题(虚构数值,不作为临床指导)。 用 Morse 跌倒评分评估一位练习患者:过去 3 个月内的跌倒史: 是; 次要诊断: 否; 行走辅助: 无、卧床休息或由护士协助; 静脉输液或封管: 否; 步态: 正常、卧床休息或轮椅; 精神状态: 了解自身局限。使用分界值 0–24 低,25–44 中度,45 或以上高,点击跌倒风险等级。
练习数值:Na⁺ 128 mmol/L,葡萄糖 6.4 mmol/L,尿素 3.2 mmol/L。计算血清渗透压 Osm = 2·Na⁺ + 葡萄糖 + 尿素,取最接近的整数。
某练习血气显示呼吸性酸中毒:pH 7.32,PaCO₂ 68 mmHg (9.1 kPa),HCO₃⁻ 34 mmol/L。利用规则“HCO₃⁻ 每 10 mmHg 升高 1 mmol/L(急性)或 3.5 mmol/L(慢性)”进行分类。点选你的答案。
解读这条 II 导联心律条带。这是什么节律?点击你的答案。
识别这条 II 导联心电图上的节律。点击你的答案。
答案: B · Past the internal sphincter, against the rectal wall
The suppository is pushed past the internal anal sphincter and placed against the rectal wall, usually with the patient lying on the left side. Placing it in stool stops absorption.
答案: C · "I'll avoid coughing so I don't hurt my stitches."
Avoiding coughing lets secretions collect and raises the risk of chest infection. Splinting the wound, deep breathing and good pain control are correct.
答案: D · Limit time close to the patient and handle body fluids per radiation policy
Radioactive iodine is excreted in urine, sweat and saliva, so the patient is usually in a private room with their own bathroom. Staff limit time near them, use distance and follow policy for body fluids and waste.
答案: B · Failure mode and effects analysis (FMEA)
FMEA is a proactive method that looks at each step of a process, asks how it could fail and what the effect would be, and changes the process in advance. Root cause analysis is used after an event has happened.
答案: D · 为病情稳定的患者置入留置导尿管
为病情稳定的患者置入导尿管是常在 LPN/LVN 范围内的技能。入院评估、初次教育和开始输血通常仍由 RN 负责。具体范围因州和国家而异。
答案: B · A possible myocardial infarction that needs urgent action
Chest pain that lasts and is not relieved by rest or nitroglycerin suggests acute coronary syndrome, possibly a heart attack. The nurse acts at once: ECG, escalation and prescribed treatment.
答案: C · 肌内注射胰高血糖素
对意识不清的低血糖患者,口服治疗有误吸风险。肌注胰高血糖素可释放肝糖原;如有静脉通路则静脉给予葡萄糖。
答案: D · Gently explore what the patient understands and what has prompted the question
Exploring the patient's understanding and feelings opens an honest conversation and shows what information they want. The nurse can then involve the team for further discussion.
答案: A · 不常规监测 aPTT;而是检查血小板和肾功能
依诺肝素的效果可预测,因此不用 aPTT 来监测。血小板计数有助于发现肝素诱导的血小板减少症,肾功能也很重要,因为该药经肾脏清除。在妊娠、肥胖或肾病时可使用抗 Xa 水平。
答案: A · "If I forget to save one void, I'll just carry on to the end"
A 24-hour collection is valid only if every void in the period is saved; if a void is lost, the nurse or clinic is told and the collection is usually restarted. Keeping the container cool as instructed, adding the final void at the end time and asking about restrictions are correct.核对依据: Urine 24-hour volume · MedlinePlus (NIH) (2025)
答案: C · 它增强抗凝血酶的作用,使凝血酶和 Xa 因子失活
肝素与抗凝血酶结合,大大加速其对凝血酶和 Xa 因子的灭活。低分子肝素主要作用于 Xa 因子。
答案: D · IV hydrocortisone and IV fluids
This suggests an adrenal crisis triggered by missed steroids and illness. Treatment is immediate IV or IM hydrocortisone, IV fluids with glucose as needed, and treating the cause.
答案: A · Patient reclined at 45° with the head turned slightly to the left
With the patient at 45°, the vertical height of the pulsation in the right internal jugular vein above the sternal angle is estimated. A height above about 3–4 cm suggests raised right-sided pressure, as in right heart failure or fluid overload.
答案: A · 手部的血液循环、感觉和活动,以及穿刺部位
桡动脉入路后,应检查压迫装置和穿刺部位有无出血或血肿,并检查手部的颜色、温度、毛细血管再充盈、感觉和活动。桡动脉闭塞和前臂骨筋膜室综合征是可能的并发症。
答案: D · The bladder is not emptying properly
A large post-void residual means incomplete emptying, for example from obstruction or a weak detrusor. It raises the risk of infection and overflow incontinence and may need intermittent catheterisation or treatment of the cause.
答案: B · 正常的 PaCO₂(正常碳酸血症)
高 CO₂ 使脑血管扩张并升高颅内压,而过度通气使其收缩,可引起脑缺血。通常以正常碳酸血症(约 4.7–5.3 kPa,即 35–40 mmHg)为目标;仅在出现即将脑疝的征象时短暂过度通气,作为确定性治疗前的过渡。
答案: C · They may increase the risk of perforation
Stimulating peristalsis can raise pressure on an inflamed appendix and may lead to rupture and peritonitis. The patient is kept nil by mouth while awaiting surgical assessment.
答案: B · Consider an alternative; if an NSAID is needed, add a PPI
Older age and a previous ulcer greatly increase NSAID-related bleeding. Safer options are considered first; if an NSAID is needed, the lowest effective dose for the shortest time is used with gastroprotection such as a PPI.
答案: D · Short breathing pauses with no colour change
Newborns breathe irregularly, with short pauses of a few seconds and no change in colour or heart rate. Apnoea of 20 seconds or more, or any pause with cyanosis or bradycardia, is abnormal.
答案: C · It can still develop after birth, so report headache or visual changes
Pre-eclampsia and eclampsia can occur up to about 6 weeks after birth, most often in the first days. Women should report severe headache, visual disturbance, upper abdominal pain or shortness of breath.
答案: B · 1250 mL per day
First 10 kg: 10 × 100 = 1000 mL. Next 5 kg: 5 × 50 = 250 mL. Total = 1250 mL per day, or about 52 mL per hour.
答案: B · Iron poisoning can cause gut bleeding, shock and liver failure hours later
Iron overdose damages the gut lining and disrupts cell metabolism, leading to vomiting, bleeding, shock, acidosis and liver failure, sometimes after a period when the child seems better. Urgent assessment is needed; deferoxamine is used for serious poisoning.
答案: B · About 6–24 hours after the last drink
Minor withdrawal symptoms begin within hours, usually 6–24 hours after the last drink. Seizures are most likely in the first 1–2 days, and delirium tremens usually appears later, around 2–3 days.
答案: B · 暂停抗精神病药并紧急寻求医疗帮助
这些表现提示抗精神病药恶性综合征。应停用抗精神病药,紧急请医生会诊,开始降温和支持治疗,并监测生命体征、肾功能和 CK。
答案: 06:20
24 小时制:下午 1 点起,小时数加 12(下午 3:45 = 15:45)。午夜到凌晨 12:59 为 00:00–00:59,中午 12:00–12:59 仍为 12:00–12:59。反过来换算时,13–23 点减 12 并标为下午;00 点变为凌晨 12 点。跨午夜计算时间要分两段:先算到 24:00(00:00),再从 00:00 算起。
答案: N = 1
量纲分析:先写出已知量,再乘以写成分数形式的换算系数(例如 60 min/1 h 或 1 mg/1000 mcg),使每个不需要的单位在分子和分母各出现一次并相互约去。只剩下所求单位时再计算。使用题目给出的等量关系,只对最终答案取整。
答案: V = 1 mL
Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.
答案: V = 2.4 mL
Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.
答案: R = 125 gtt/min
Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.
使用微滴输液器(60 gtt/mL)时,gtt/min 等于 mL/h。
答案: R = 40 gtt/min
Dose-based infusions: concentration = amount of drug in the bag/bag volume. Pump rate (mL/h) = dose per hour/concentration, and dose per hour = mL/h × concentration. Convert per-minute doses to per-hour (× 60) and keep the mass units the same (1 g = 1000 mg, 1 mg = 1000 mcg).
答案: V = 3.7 mL
肝素和胰岛素输注:浓度 = 袋中单位数/袋容量 (units/mL)。泵速 (mL/h) = 每小时单位数/浓度,每小时单位数 = mL/h × 浓度。按体重给药时,先求 units/h = units/kg/h × 体重。推注体积 = 所需单位数/药瓶规格。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: R = 3 mL/h
滴定输注:先求以 mcg/mL 计的浓度(mg × 1000/mL)。按体重给药时,mcg/min = mcg/kg/min × 体重。然后 mL/h = mcg/min × 60/浓度。反推时,mcg/kg/min = mL/h × 浓度/(60 × 体重)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
医嘱是针对患者整体的每分钟剂量,所以不需要体重。
答案: B = −210 mL
出入量:入量计入所有进入体内的液体(口服液体、静脉输液、静脉用药及冲管液、管饲);冰屑按其体积的一半计。出量计入尿液、引流液、呕吐物和其他丢失。平衡 = 总入量 − 总出量;平衡为负表示净丢失。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
为负:患者丢失的液体多于摄入的液体。
答案: V = 560 mL
输液时间:时间 (h) = 待输体积 (mL)/速率 (mL/h);使用袋中剩余的体积,而不是袋的容量。已输入体积 = 速率 × 时间。把小数小时换算为小时和分钟时,用小数部分 × 60(0.5 h = 30 min,而不是 50 min)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: B = 13
Braden 量表:评估压力性损伤风险的六个分项。感觉知觉、潮湿程度、活动、活动能力和营养各评 1 至 4 分,从最差水平(1)到无问题(4);摩擦力和剪切力评 1 至 3 分。总分为 6 至 23,总分越低风险越高。常用分级:19–23 无风险,15–18 轻度风险,13–14 中度风险,10–12 高风险,9 分及以下为极高风险。
答案: 中度风险
Morse 跌倒评分:六个条目。跌倒史:否 0 分,是 25 分。次要诊断:否 0 分,是 15 分。行走辅助:无、卧床休息或护士协助 0 分;拐杖、手杖或助行器 15 分;扶着家具 30 分。静脉输液或封管:否 0 分,是 20 分。步态:正常、卧床休息或轮椅 0 分;虚弱 10 分;受损 20 分。精神状态:了解自身局限 0 分;高估或忘记自身局限 15 分。总分为 0 至 125。各医院的风险分界值不同;常用的一套是 0–24 低风险,25–44 中度风险,45 及以上为高风险。
答案: Osm = 266 mOsm/kg
衍生数值:计算所得的血清渗透压为 2·Na⁺ + 葡萄糖 + 尿素,各值均以 mmol/L 计(葡萄糖和 BUN 以 mg/dL 计时为 2·Na⁺ + 葡萄糖/18 + BUN/2.8);正常约为 275–295 mOsm/kg。P/F 比值是 PaO₂ 除以以小数表示的 FiO₂。海平面的肺泡氧分压为 PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg,A–a 梯度为 PAO₂ − PaO₂。
答案: 慢性
预期代偿:代谢性酸中毒时,温特公式预测 PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg;实测值高于该范围提示合并呼吸性酸中毒,低于该范围提示合并呼吸性碱中毒。阴离子间隙 AG = Na⁺ − (Cl⁻ + HCO₃⁻),正常约为 8–12 mmol/L,用于区分高阴离子间隙与正常阴离子间隙代谢性酸中毒;低白蛋白会掩盖升高的间隙(白蛋白低于 4.0 的部分,每 g/dL 加 2.5)。Δ 比值 (AG − 12)/(24 − HCO₃⁻) 约在 0.8 到 2 之间符合单纯高间隙酸中毒(有些教材用 1 代替 0.8),低于此范围提示合并正常间隙酸中毒,高于 2 提示合并代谢性碱中毒。
答案: 室性二联律
节律标准(II 导联):窦性心律每个 QRS 之前都有直立的 P 波,PR 恒定为 0.12–0.20 s,QRS 狭窄:60–100 次/分为正常窦性心律,低于 60 为窦性心动过缓,高于 100 为窦性心动过速。心房颤动:无 P 波,基线呈颤动,R–R 绝对不规则。心房扑动:约 250–350 次/分的锯齿状扑动波,伴固定的传导比例,如 2:1 或 4:1。一度房室传导阻滞:窦性心律,PR 恒定且大于 0.20 s。交界性心律:窄 QRS,40–60 次/分,P 波缺失或倒置(PR 低于 0.12 s,或 P 波在 QRS 之后)。室性早搏(PVC)是提前出现的宽大(0.12 s 或以上)、形态怪异的 QRS,没有 P 波,T 波方向相反,通常有完全性代偿间歇;二联律是指每隔一个搏动就有一个室性早搏。
答案: 尖端扭转型室性心动过速
更多室性心律:尖端扭转型室性心动过速是一种多形性室性心动过速,通常为 150–250 次/分钟,其增宽的波群高度不断变化并围绕基线扭转,先向上几个心搏,再向下。教科书将其与 QT 间期延长联系起来,复苏指南中针对它推荐的药物是硫酸镁。室性自搏心律是一种心室逸搏心律:规则、QRS 增宽(0.12 s 或以上)、无 P 波,频率 20–40 次/分钟(加速性室性自搏心律为 40–100 次/分钟)。单形性室速的增宽波群完全相同,频率超过 100 次/分钟。室颤则是混乱的,没有任何重复的波群。
尖端扭转型室性心动过速是与 QT 间期延长相关的多形性 VT。这里只是识别练习。
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