感染控制与患者安全
方法
- 对每位患者都从标准预防开始:手卫生、针对预期暴露的个人防护装备、安全使用锐器。
- 按传播途径追加预防措施:接触传播(隔离衣、手套)、飞沫传播(外科口罩)、空气传播(N95、负压病房)。
- 保持无菌物品的无菌状态:如有疑问就视为不无菌;更换,绝不擦拭。
- 预防环境中的伤害:防跌倒措施,约束仅作为最后手段,火灾时用 RACE 和 PASS。
- 核对给药的正确原则、两个身份识别信息,以及对高警示药物的额外保障;报告差错和险兆事件。
公式表、每个专题的关键方法步骤和 40 道练习题,完整解答附在最后。
At what angle is an intramuscular injection given?
A patient asks for a same-sex nurse for intimate care because of their religious beliefs. What should the nurse do?
When should blood specimen tubes be labeled?
A patient dies after a wrong-drug error, and the hospital carries out a root cause analysis. What is its main focus?
A patient with angina is taught to use sublingual nitroglycerin (GTN). Which statement shows a need for further teaching?
一名大手术后的患者连续两小时尿量为 15 mL/h,心率 115 次/分,双手发凉。护士应首先做什么?
Why are alternate sutures sometimes removed first when taking out stitches?
Which patient should the nurse assess first?
A patient's potassium is unexpectedly 5.8 mEq/L. The sample was taken after the tourniquet was on for several minutes while the patient pumped their fist. What is the best interpretation?
Two weeks after a sore throat, a child develops dark (cola-colored) urine, puffy eyes and high blood pressure. Urinalysis shows red cell casts and protein. Which condition is most likely?
Which group of signs suggests opioid withdrawal?
A patient with severe liver cirrhosis needs a benzodiazepine for alcohol withdrawal. Why is lorazepam often chosen instead of diazepam?
Why must anti-embolism stockings be measured and fitted correctly?
一名 COPD 患者呼吸困难,未吸氧时 SpO₂ 84%。血气分析显示 pH 7.30,PaCO₂ 升高,尽管已给予最佳药物治疗。可能会考虑哪种治疗?
A conscious patient with a glucose of 3.1 mmol/L (56 mg/dL) can swallow safely. Which is the best first treatment?
A man who takes tamsulosin for BPH is listed for cataract surgery. Which statement is correct?
Why are laxatives and enemas avoided when appendicitis is suspected?
Two days after a PEG insertion, a patient reports pain on feeding, and feed is leaking around the site. What should the nurse do?
Why is the hearing of newborns screened before discharge or soon after birth?
A newborn whose mother had a fever and prolonged rupture of membranes is well at birth. Why does the nurse monitor this baby closely?
Which group of findings suggests Kawasaki disease?
一名幼儿 30 分钟前吞下了一枚纽扣电池,看起来状态良好。正确的做法是什么?
What must a patient be told for consent to a new psychotropic medicine to be valid?
A patient asks the nurse to pray with her before her ECT. The nurse does not share her religion. What is the most appropriate response?
练习题(虚构数值,不作为临床指导)。 一次体重换算得到 60.0158 kg。 本练习的规则是:体重取到最接近的十分之一千克。你记录的数值x是多少?
练习题(虚构数值,不作为临床指导)。 一张处方写着口服混悬液2 tsp,每 8 小时一次,共 7 天。按1 tsp = 5 mL,整个疗程需要多少 mLV?
一名体重 22 kg 的患者体表面积为 0.89 m²。医嘱为 100 mg/m²。求剂量 D,以 mg 表示。
处方剂量为 0.84 mg。安瓿每 mL 含 1000 微克。请用 1 mL 注射器抽取剂量:应给多少体积 V?
用滴系数为 10 滴/mL 的输液器在 5 小时内输入 500 mL。求滴速 R(滴/分)。 取整到最接近的整数。
一袋中含有 2 g 药物,溶于 250 mL。医嘱为每分钟 1 mg。泵速 R 应设为多少 mL/h?
练习题(虚构数值,不作为临床指导)。 一份输液含普通胰岛素 100 单位,容量 100 mL。医嘱为 10 units/h。求泵速 R,以 mL/h 计。 保留一位小数。
练习题(虚构数值,不作为临床指导)。 一袋中含dobutamine 250 mg,容量 250 mL。医嘱为 2.5 mcg/kg/min,患者体重 85 kg。输液泵速率 R 应设为多少 mL/h? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 记录显示了一名患者在一个 12 小时班次中的出入量。静脉输液在整个班次中按所示速率输注。求液体平衡 B = 入量 − 出量,以 mL 计(答案为负表示净丢失)。
练习题(虚构数值,不作为临床指导)。 一份 1000 mL 的输液于 13:30 开始以 150 mL/h 输注。3 小时后速率改为 100 mL/h,之后不再改变。从开始算起多少小时 t 后袋子会输完? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 用 Braden 量表评估一位练习患者:感觉知觉: 完全受限; 潮湿程度: 很少潮湿; 活动: 经常步行; 活动能力: 不受限制; 营养: 极好; 摩擦力和剪切力: 有问题。求 Braden 总分B。
练习题(虚构数值,不作为临床指导)。 用 Braden 量表评估一位练习患者:感觉知觉: 非常受限; 潮湿程度: 持续潮湿; 活动: 局限于椅子; 活动能力: 非常受限; 营养: 充足; 摩擦力和剪切力: 潜在问题。使用的分级为:19–23 无风险,15–18 轻度,13–14 中度,10–12 高,9 或以下极高。点击风险等级。
某练习血气显示代谢性酸中毒,HCO₃⁻ 8 mmol/L。用温特公式求预期PaCO₂(范围的中心),单位 mmHg。
某练习血气显示代谢性酸中毒:pH 7.18,PaCO₂ 39 mmHg (5.2 kPa),HCO₃⁻ 14 mmol/L。把实测的PaCO₂与温特公式比较。点选你的解读。
这条 II 导联心电图显示传导比例固定的心房扑动。求出心室率(单位:次/分)。
依次按五个步骤解读这条 II 导联心电图:心率、节律、P 波、PR 间期、QRS 时限。你在哪一步发现第一个异常?点击它。
答案: C · 90 degrees
Intramuscular injections are given at 90 degrees so the needle passes through the skin and fat into the muscle. Intradermal injections use about 10–15 degrees.
答案: C · Arrange it where possible and record the preference in the care plan
Respecting such preferences supports dignity and trust. The nurse arranges it whenever possible, records it and explains if it cannot be met in an emergency.
答案: D · At the bedside, in front of the patient, right after collection
Labeling tubes at the bedside, using two patient identifiers and in the patient’s presence, prevents wrong-patient specimens. Pre-labeled or later-labeled tubes are easily mixed up.
答案: A · Finding the system and process weaknesses that allowed the error
A root cause analysis looks beyond the individual to the system factors, such as storage, labeling, staffing or workflow, that allowed the error. The aim is to change the system so the error cannot happen again.
答案: B · “I will take five tablets one after the other before I call for help.”
Action plans differ slightly: US guidance says to call emergency services if pain is not better 5 minutes after the first dose, while UK guidance allows a second dose after 5 minutes and a 999 call if pain persists 5 minutes later. Taking many doses in a row delays care and can cause severe hypotension.
答案: D · 评估休克的征象,如出血,并上报
这些征象合起来提示低血容量或休克。护士应评估整个患者,寻找出血并上报。应排除导尿管问题,但不应延误对休克的识别。
答案: B · To check the wound stays closed before removing the rest
Removing alternate sutures allows the nurse to see whether the wound edges stay together. If they begin to separate, the remaining sutures can be left and the team informed.
答案: A · A patient with asthma who can only speak in single words
Being unable to complete sentences is a sign of acute severe or life-threatening asthma, an airway and breathing emergency. The other patients need attention but are not immediately life-threatened.
答案: A · The result may be falsely high and should be repeated with better technique
Repeated fist clenching and a long tourniquet time release potassium from muscle and can cause hemolysis, both of which give a falsely high potassium. The patient is assessed and the test is repeated with correct technique; true hyperkalemia must not be missed.核对依据: Potassium Blood Test · MedlinePlus (NIH) (2024); Potassium test · MedlinePlus (NIH) (2025)
答案: C · Post-streptococcal glomerulonephritis
Red cell casts show bleeding from the glomeruli, which is typical of glomerulonephritis. After a streptococcal infection, immune complexes inflame the glomeruli, causing hematuria, proteinuria, edema and hypertension. Cystitis and stones do not cause red cell casts.核对依据: Strep A Test · MedlinePlus (NIH) (2024)
答案: C · Yawning, runny nose, sweating, dilated pupils and diarrhoea
Opioid withdrawal causes rhinorrhoea, lacrimation, yawning, sweating, mydriasis, cramps, diarrhoea and anxiety. It is very unpleasant but rarely life-threatening in healthy adults.
答案: D · Lorazepam is cleared by simple conjugation and has no active metabolites
Diazepam is metabolised by CYP enzymes into long-acting active metabolites, which accumulate in liver failure. Lorazepam, oxazepam and temazepam are glucuronidated, a process better preserved in liver disease.
答案: B · Poorly fitting stockings can cause pressure damage
Stockings that are the wrong size or that roll down can act like a tourniquet and cause skin and pressure damage. They are measured to the leg, checked daily, and avoided in significant peripheral arterial disease, severe neuropathy or leg skin damage.
答案: C · 无创通气(NIV)
在 COPD 急性加重伴呼吸性酸中毒(pH < 7.35 且 PaCO₂ 升高)、经最佳药物治疗仍持续存在时,NIV 可降低死亡率和插管需求。继续控制性氧疗,目标为 88–92%。不受控制的高流量氧气和镇静药可使 CO₂ 潴留加重。
答案: D · Glucose tablets or a small glass of fruit juice
About 15–20 g of fast-acting carbohydrate, such as glucose tablets or juice, raises glucose quickly. Chocolate and milk contain fat, which slows absorption. Glucose is rechecked after about 15 minutes.
答案: D · The eye surgeon must be told, as it can cause floppy iris during surgery
Tamsulosin blocks alpha-1A receptors in the iris dilator muscle as well as in the prostate, which can cause intraoperative floppy iris syndrome during cataract surgery. The effect can persist after the drug is stopped, so the surgeon must know in advance to plan the operation. Whether to pause it is a decision for the team.
答案: B · They may increase the risk of perforation
Stimulating peristalsis can raise pressure on an inflamed appendix and may lead to rupture and peritonitis. The patient is kept nil by mouth while awaiting surgical assessment.
答案: D · Stop the feed at once and seek urgent medical advice
Pain on feeding, external leakage or new bleeding soon after PEG insertion may mean feed is leaking into the peritoneum. Feeding and medicines are stopped immediately and senior review is arranged to exclude peritonitis.
答案: B · Early support improves language development
Early detection of hearing loss allows hearing aids, cochlear implants or other support in the first months, which greatly improves language outcomes.
答案: C · The baby has a higher risk of early sepsis
Maternal fever, prolonged rupture of membranes and intra-amniotic infection are risk factors for early-onset sepsis. Many protocols require observation of vital signs and feeding, and sometimes blood tests or antibiotics.
答案: A · Fever for at least 5 days, red eyes without discharge, cracked red lips and swollen hands and feet
Kawasaki disease causes persistent fever plus features such as non-purulent conjunctivitis, red cracked lips and strawberry tongue, rash, swollen hands and feet and enlarged neck lymph nodes. The other options describe croup, chickenpox and roseola.
答案: B · 安排立即转送急诊,进行影像学检查和取出
食管内的纽扣电池可在 2 小时内造成严重灼伤。即使孩子看起来状态良好,也需要紧急 X 线检查,如果电池在食管内,需要内镜取出。
答案: C · The expected benefits, the main risks and the alternatives, including no treatment
Valid consent requires that the patient has capacity, has enough information about benefits, risks and alternatives, and decides voluntarily. A mental illness does not automatically remove capacity.
答案: A · Respect the request, join in if comfortable, and offer to call the chaplain
Supporting spiritual needs can reduce distress. The nurse can respond with respect within her own comfort, and refer to chaplaincy or faith leaders, without imposing her own beliefs.
答案: x = 60 kg
取整:看舍入位后面的那个数字:5 或更大则进位,4 或更小则保持原数字不变。只对最终答案取整,绝不对中间步骤取整。典型的考试规则:1 mL 或以上的体积取到十分位,低于 1 mL 的体积取到百分位,滴速取整到整滴,体重取到一位小数;务必遵循题目所规定的规则。
答案: V = 210 mL
量纲分析:先写出已知量,再乘以写成分数形式的换算系数(例如 60 min/1 h 或 1 mg/1000 mcg),使每个不需要的单位在分子和分母各出现一次并相互约去。只剩下所求单位时再计算。使用题目给出的等量关系,只对最终答案取整。
答案: D = 89 mg
Body-surface-area dosing: many cytotoxic and some paediatric doses are prescribed per square metre of body surface area: dose (mg) = dose per m² × BSA (m²). The Mosteller formula estimates BSA = √(height (cm) × weight (kg)/3600).
答案: V = 0.84 mL
抽取剂量:体积 = (处方剂量/药物浓度) × 药物体积。先换算成相同的单位,再检查该体积是否适合注射器,并落在它的某一个刻度上。
答案: R = 17 gtt/min
输注速率:输液泵按 mL/h = 体积/时间(小时)设定。重力滴注按每分钟滴数计:gtt/min = 体积 (mL) × 滴系数 (gtt/mL)/时间 (min)。 滴系数印在输液器包装上:普通输液器为 10、15 或 20 gtt/mL(输血器在美国常为 10 gtt/mL,在英国为 15),微量输液器为 60 gtt/mL。务必使用题目或包装给出的滴系数。
床旁取最接近的整滴:17 滴/分。
答案: R = 7.5 mL/h
Dose-based infusions: concentration = amount of drug in the bag/bag volume. Pump rate (mL/h) = dose per hour/concentration, and dose per hour = mL/h × concentration. Convert per-minute doses to per-hour (× 60) and keep the mass units the same (1 g = 1000 mg, 1 mg = 1000 mcg).
答案: R = 10 mL/h
肝素和胰岛素输注:浓度 = 袋中单位数/袋容量 (units/mL)。泵速 (mL/h) = 每小时单位数/浓度,每小时单位数 = mL/h × 浓度。按体重给药时,先求 units/h = units/kg/h × 体重。推注体积 = 所需单位数/药瓶规格。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: R = 12.8 mL/h
滴定输注:先求以 mcg/mL 计的浓度(mg × 1000/mL)。按体重给药时,mcg/min = mcg/kg/min × 体重。然后 mL/h = mcg/min × 60/浓度。反推时,mcg/kg/min = mL/h × 浓度/(60 × 体重)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: B = 1145 mL
出入量:入量计入所有进入体内的液体(口服液体、静脉输液、静脉用药及冲管液、管饲);冰屑按其体积的一半计。出量计入尿液、引流液、呕吐物和其他丢失。平衡 = 总入量 − 总出量;平衡为负表示净丢失。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
为正:摄入的液体多于排出的液体。
答案: t = 8.5 h
输液时间:时间 (h) = 待输体积 (mL)/速率 (mL/h);使用袋中剩余的体积,而不是袋的容量。已输入体积 = 速率 × 时间。把小数小时换算为小时和分钟时,用小数部分 × 60(0.5 h = 30 min,而不是 50 min)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
约为 8 h 30 min,所以袋子大约在 22:00 输完。
答案: B = 18
Braden 量表:评估压力性损伤风险的六个分项。感觉知觉、潮湿程度、活动、活动能力和营养各评 1 至 4 分,从最差水平(1)到无问题(4);摩擦力和剪切力评 1 至 3 分。总分为 6 至 23,总分越低风险越高。常用分级:19–23 无风险,15–18 轻度风险,13–14 中度风险,10–12 高风险,9 分及以下为极高风险。
答案: 高风险
Braden 量表:评估压力性损伤风险的六个分项。感觉知觉、潮湿程度、活动、活动能力和营养各评 1 至 4 分,从最差水平(1)到无问题(4);摩擦力和剪切力评 1 至 3 分。总分为 6 至 23,总分越低风险越高。常用分级:19–23 无风险,15–18 轻度风险,13–14 中度风险,10–12 高风险,9 分及以下为极高风险。
答案: PaCO₂ = 20 mmHg
预期代偿:代谢性酸中毒时,温特公式预测 PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg;实测值高于该范围提示合并呼吸性酸中毒,低于该范围提示合并呼吸性碱中毒。阴离子间隙 AG = Na⁺ − (Cl⁻ + HCO₃⁻),正常约为 8–12 mmol/L,用于区分高阴离子间隙与正常阴离子间隙代谢性酸中毒;低白蛋白会掩盖升高的间隙(白蛋白低于 4.0 的部分,每 g/dL 加 2.5)。Δ 比值 (AG − 12)/(24 − HCO₃⁻) 约在 0.8 到 2 之间符合单纯高间隙酸中毒(有些教材用 1 代替 0.8),低于此范围提示合并正常间隙酸中毒,高于 2 提示合并代谢性碱中毒。
答案: 合并呼吸性酸中毒
预期代偿:代谢性酸中毒时,温特公式预测 PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg;实测值高于该范围提示合并呼吸性酸中毒,低于该范围提示合并呼吸性碱中毒。阴离子间隙 AG = Na⁺ − (Cl⁻ + HCO₃⁻),正常约为 8–12 mmol/L,用于区分高阴离子间隙与正常阴离子间隙代谢性酸中毒;低白蛋白会掩盖升高的间隙(白蛋白低于 4.0 的部分,每 g/dL 加 2.5)。Δ 比值 (AG − 12)/(24 − HCO₃⁻) 约在 0.8 到 2 之间符合单纯高间隙酸中毒(有些教材用 1 代替 0.8),低于此范围提示合并正常间隙酸中毒,高于 2 提示合并代谢性碱中毒。
答案: 心室率 = 100 bpm
节律标准(II 导联):窦性心律每个 QRS 之前都有直立的 P 波,PR 恒定为 0.12–0.20 s,QRS 狭窄:60–100 次/分为正常窦性心律,低于 60 为窦性心动过缓,高于 100 为窦性心动过速。心房颤动:无 P 波,基线呈颤动,R–R 绝对不规则。心房扑动:约 250–350 次/分的锯齿状扑动波,伴固定的传导比例,如 2:1 或 4:1。一度房室传导阻滞:窦性心律,PR 恒定且大于 0.20 s。交界性心律:窄 QRS,40–60 次/分,P 波缺失或倒置(PR 低于 0.12 s,或 P 波在 QRS 之后)。室性早搏(PVC)是提前出现的宽大(0.12 s 或以上)、形态怪异的 QRS,没有 P 波,T 波方向相反,通常有完全性代偿间歇;二联律是指每隔一个搏动就有一个室性早搏。
答案: QRS 时限
每条心电图的五个步骤:1. 心率(300 法或 1500 法;若不规则则用 6 秒法);2. 节律:R–R 间期是否相等;3. P 波:是否存在、在 II 导联直立、每个 QRS 之前各有一个且形态一致;4. PR 间期:0.12–0.20 s 且恒定;5. QRS 时限:低于 0.12 s。五个步骤做完之后才命名节律。正常窦性心律五项全部符合:60–100 次/分,规则,每个 QRS 之前有直立 P 波,PR 0.12–0.20 s,QRS 低于 0.12 s。
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