感染控制与患者安全
方法
- 对每位患者都从标准预防开始:手卫生、针对预期暴露的个人防护装备、安全使用锐器。
- 按传播途径追加预防措施:接触传播(隔离衣、手套)、飞沫传播(外科口罩)、空气传播(N95、负压病房)。
- 保持无菌物品的无菌状态:如有疑问就视为不无菌;更换,绝不擦拭。
- 预防环境中的伤害:防跌倒措施,约束仅作为最后手段,火灾时用 RACE 和 PASS。
- 核对给药的正确原则、两个身份识别信息,以及对高警示药物的额外保障;报告差错和险兆事件。
公式表、每个专题的关键方法步骤和 40 道练习题,完整解答附在最后。
什么是直立性(体位性)低血压?
Why is heat usually avoided on a fresh soft-tissue injury during the first day?
A patient walking with a gait belt suddenly starts to fall. What should the nurse do?
A child with fever, cough, red eyes and a spreading rash is in a clinic waiting room. Measles is suspected. What should the nurse do first?
Two nursing assistants argue loudly at the station about their assignments. What is the charge nurse’s best first step?
在资源极其有限的灾难中,一名几乎全身严重烧伤的伤员被标为黑色。哪项原则解释了这个决定?
Which rule is essential for safe use of patient-controlled analgesia (PCA)?
A postoperative patient on IV fluids has a sodium of 128 mmol/L and is becoming confused. Which fluid could make this worse if given in large amounts?
一名服用呋塞米的患者钾为 2.9 mEq/L。护士预期会出现哪项发现?
一名慢性肾脏病患者磷酸盐为 7.2 mg/dL(2.3 mmol/L)。哪项饮食指导最恰当?
Why is hypovolaemia corrected with IV fluids before or while starting a vasopressor?
A patient who takes clonidine stopped it suddenly two days ago. He is now agitated, has a headache and his blood pressure is very high. What is the most likely explanation?
Why is pyridoxine (vitamin B6) often given with isoniazid?
A patient with severe COPD has increasing ankle oedema and a raised JVP, but no crackles and a normal left ventricle on echocardiography. Which condition is most likely?
哪个格拉斯哥昏迷量表评分通常提示患者可能无法保护自己的气道?
An older man was found on the floor after lying there for many hours. His urine is dark brown, and his creatine kinase is very high. What is the main kidney risk and the key treatment?
Why is it important to prevent perioperative hypothermia?
急性胰腺炎最初几小时,通常推荐哪种补液策略?
Progesterone relaxes smooth muscle in pregnancy. Which common complaint does this help explain?
A woman with active genital herpes lesions is admitted in early labour with intact membranes. What should the nurse expect?
A child with type 1 diabetes is unconscious from hypoglycaemia at school. What should be done?
An infant with a large VSD now breathes faster, sweats during feeds and has gained 300 g overnight with puffy eyelids. What does this most likely indicate?
A patient taking oxycodone for chronic pain has also been prescribed diazepam. What is the main safety concern?
An 8-year-old taking methylphenidate for 6 months has dropped from the 50th to the 25th centile for weight. What is the most appropriate nursing action?
练习题(虚构数值,不作为临床指导)。 一名新生儿体重 5 lb 2 oz。按 1 lb = 16 oz 和 1 kg = 2.2 lb,求以千克表示的体重m。取到两位小数。
练习题(虚构数值,不作为临床指导)。 医嘱为 5 mcg/kg/min,患者体重 58 kg。请把剂量速率D用 mg/h 表示。取到两位小数。
一个药瓶中含有 2 g 的粉末。标签上写着:加入 9.2 mL 注射用水,得到总容量 10 mL。医嘱为 300 mg。你应给予复溶后溶液的多少容量 V?
处方剂量为 0.45 mg。安瓿每 mL 含 1000 微克。请用 1 mL 注射器抽取剂量:应给多少体积 V?
医嘱要求以 75 mL/h 输液,但没有输液泵。改用滴系数为 60 gtt/mL 的输液器重力滴注。求滴速 R,以每分钟滴数表示。
一袋中含有 1 g 药物,溶于 500 mL。医嘱为每分钟 1 mg。泵速 R 应设为多少 mL/h?
练习题(虚构数值,不作为临床指导)。 一份输液含普通胰岛素 100 单位,容量 250 mL。医嘱为 0.05 units/kg/h,患者体重 74 kg。求泵速 R,以 mL/h 计。 保留一位小数。
练习题(虚构数值,不作为临床指导)。 一袋中含dopamine 800 mg,容量 500 mL。医嘱为 6 mcg/kg/min,患者体重 88 kg。输液泵速率 R 应设为多少 mL/h? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 记录显示了一名患者在一个 12 小时班次中的出入量。患者体重 84 kg。求平均尿量 U,以 mL/kg/h 计。 保留两位小数。
练习题(虚构数值,不作为临床指导)。 一份 1000 mL 的输液于 16:30 开始以 80 mL/h 输注。4 小时后速率改为 60 mL/h,之后不再改变。从开始算起多少小时 t 后袋子会输完? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 用 Braden 量表评估一位练习患者:感觉知觉: 非常受限; 潮湿程度: 持续潮湿; 活动: 局限于椅子; 活动能力: 完全不能活动; 营养: 充足; 摩擦力和剪切力: 有问题。求 Braden 总分B。
练习题(虚构数值,不作为临床指导)。 对这些观察结果使用 NEWS2 图表(SpO₂ 量表 1):呼吸频率 20 次/分,SpO₂ 98%吸室内空气,血压 118/70 mmHg,脉搏 58 次/分,仅对声音有反应,体温 36.2 °C。患者属于哪个临床风险组?点击它。
某练习血气显示 PaCO₂ 54 mmHg (7.2 kPa)。利用规则:在慢性呼吸性酸中毒中,PaCO₂ 每比 40 高出 10 mmHg,HCO₃⁻ 升高 3.5 mmol/L,以HCO₃⁻ 24 mmol/L 为起点,求预期HCO₃⁻。
某练习血气显示 pH 7.32,PaCO₂ 28 mmHg (3.7 kPa),HCO₃⁻ 14 mmol/L,Na⁺ 134,Cl⁻ 93 mmol/L。利用阴离子间隙和 Δ 比值,点选最合适的解读。
解读这条 II 导联心律条带。这是什么节律?点击你的答案。
请解读这条 II 导联心电图条带。仅凭这一条心电图条带,你能为哪种解读辩护?点击你的答案。
答案: C · 站起时血压下降,常引起头晕
直立性低血压是转为直立体位时血压下降。它在老年人中以及服用某些药物时很常见,会增加跌倒风险。
答案: A · It widens blood vessels and can increase swelling and bleeding
Heat causes vasodilation, which can worsen swelling and bleeding in an acute injury. Cold is used first; heat may help later with stiffness.
答案: B · Hold the belt, widen the stance and ease the patient gently to the floor
The nurse keeps hold of the gait belt, takes a wide base of support and slides the patient down along their own leg to the floor, protecting the head. This controls the fall and protects the nurse’s back.
答案: A · Put a mask on the child and move them into an airborne isolation room
Measles is highly contagious through airborne spread. The child is masked and placed in an airborne infection isolation room, or a closed single room if none is available, and exposed people may need follow-up.
答案: A · Meet both of them privately to hear each side
Talking with both staff members privately allows the charge nurse to understand the problem and look for a fair solution. Ignoring the conflict or acting without facts usually makes it worse.
答案: A · 为最多的人做最大的好事
在大规模伤亡事件中,资源用在能挽救最多生命的地方。即使给予全面治疗也不太可能存活的伤员接受安宁照护,而工作人员则救治可挽救的伤员。在日常分诊中,通常先看病情最重的患者。
答案: C · Only the patient should press the button
If the patient becomes too sedated, they stop pressing the button, which protects them. When others press it, this safety mechanism is lost and overdose can occur.
答案: D · 5% glucose (D5W)
The glucose in 5% glucose is metabolised, leaving free water that dilutes the plasma sodium further. Postoperative patients often have raised ADH, so large volumes of hypotonic fluid can cause dangerous hyponatraemia.
答案: B · 肌肉无力和腿部抽筋
低钾引起肌肉无力、抽筋、肠蠕动减弱(便秘,甚至肠麻痹)和心律失常。T 波高尖见于高钾血症,口周麻刺感提示低钙。核对依据: Heart failure - fluids and diuretics · MedlinePlus (NIH); Low blood potassium · MedlinePlus (NIH) (2025)
答案: B · 限制富含磷酸盐的食物,如加工食品和可乐
CKD 中的高磷通过限制磷摄入、随餐服用结合剂和透析来处理。含有磷酸盐添加剂的加工食品、可乐和大量乳制品是主要来源。核对依据: Phosphorus: Tips for People with Chronic Kidney Disease · Indian Health Service (HHS); Phosphorus and Your Kidneys · National Kidney Foundation (2024); Chronic kidney disease · MedlinePlus (NIH) (2025)
答案: D · Vasopressors cannot keep perfusion up if the circulation is under-filled
Vasoconstriction without adequate volume reduces organ blood flow and can cause ischaemia. Fluid resuscitation restores preload, and vasopressors are then used for persistent hypotension.
答案: B · Rebound hypertension from abrupt clonidine withdrawal
Clonidine is a central alpha-2 agonist. Stopping it suddenly lets sympathetic activity surge, causing rebound hypertension, so it is tapered gradually.
答案: D · To prevent peripheral neuropathy
Isoniazid increases pyridoxine loss, which can cause peripheral neuropathy, especially in people with diabetes, alcohol dependence, malnutrition or HIV. Pyridoxine prevents this. Isoniazid can also cause hepatitis. Ethambutol affects vision; pyrazinamide can cause gout.
答案: D · Cor pulmonale
Chronic hypoxia in COPD causes pulmonary hypertension, which strains the right ventricle and leads to right heart failure with oedema and raised JVP. Management includes treating hypoxia (long-term oxygen if eligible), diuretics for oedema and optimising COPD treatment.
答案: B · 8 分或以下
GCS 8 分或以下通常表示昏迷,且患者有无法维持或保护气道的风险,因此需要紧急的高级医师和麻醉科评估。评分范围为 3 到 15 分,应分别报告各项(E、V、M)。
答案: B · AKI from rhabdomyolysis, treated with generous IV fluids
Prolonged pressure damages muscle (rhabdomyolysis), releasing myoglobin, which is toxic to the tubules, as well as potassium. Early, generous IV fluids with close monitoring of urine output, potassium and creatinine help protect the kidneys.
答案: D · It increases bleeding, wound infection and heart complications
Even mild hypothermia impairs clotting, increases surgical site infection and cardiac events, and causes shivering and discomfort. Forced-air warming, warmed fluids and covering the patient help prevent it.
答案: C · 以目标为导向的平衡晶体液,根据反应调整
胰腺炎使液体丢失到组织中,所以早期静脉补液很重要。最新指南倾向于使用哈特曼液或乳酸林格液等平衡晶体液进行适度、以目标为导向的复苏,并根据心率、血压和尿量调整,因为过于积极的补液只会增加负荷而没有益处。
答案: A · Constipation
Progesterone slows gut motility, which causes constipation and contributes to heartburn because the lower oesophageal sphincter relaxes. Gum bleeding and nasal stuffiness are mainly due to oestrogen and increased blood flow.
答案: B · A caesarean birth to reduce the risk of neonatal herpes
Active genital lesions or prodromal symptoms at the onset of labour are an indication for caesarean birth because neonatal herpes can be severe. Invasive procedures such as scalp electrodes are avoided.
答案: C · Give glucagon and call emergency services
An unconscious child cannot swallow safely, so glucagon is given by injection or nasal spray, the child is placed in the recovery position and emergency help is called. Once awake and able to swallow, carbohydrate is given.
答案: B · Worsening heart failure with fluid retention
A sudden overnight weight gain with periorbital oedema, tachypnoea and sweating suggests fluid retention from worsening heart failure. Daily weights on the same scale are a key way to monitor fluid status in these infants.
答案: A · Increased sedation and respiratory depression
Combining opioids with benzodiazepines greatly increases the risk of sedation, respiratory depression and death. Patients are monitored and taught to avoid alcohol and other sedatives.
答案: B · Report the finding, review his eating pattern and suggest giving the medicine after breakfast
Appetite suppression is a common stimulant effect and can affect growth. The prescriber needs to know, and strategies such as giving the dose after breakfast and offering a good evening meal can help.
答案: m = 2.33 kg
家用计量和体重:护理考试使用取整的等量关系:1 茶匙(tsp)= 5 mL,1 汤匙(tbsp)= 15 mL = 3 tsp,1 液量盎司(fl oz)= 30 mL = 2 tbsp,1 杯 = 8 fl oz = 240 mL。体重方面,1 kg = 2.2 lb,1 lb = 16 oz;长度方面,1 英寸 = 2.54 cm。设置换算时,要让你不需要的单位相互约去。
答案: D = 17.4 mg/h
量纲分析:先写出已知量,再乘以写成分数形式的换算系数(例如 60 min/1 h 或 1 mg/1000 mcg),使每个不需要的单位在分子和分母各出现一次并相互约去。只剩下所求单位时再计算。使用题目给出的等量关系,只对最终答案取整。
答案: V = 1.5 mL
Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.
答案: V = 0.45 mL
抽取剂量:体积 = (处方剂量/药物浓度) × 药物体积。先换算成相同的单位,再检查该体积是否适合注射器,并落在它的某一个刻度上。
答案: R = 75 gtt/min
Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.
使用微滴输液器(60 gtt/mL)时,gtt/min 等于 mL/h。
答案: R = 30 mL/h
Dose-based infusions: concentration = amount of drug in the bag/bag volume. Pump rate (mL/h) = dose per hour/concentration, and dose per hour = mL/h × concentration. Convert per-minute doses to per-hour (× 60) and keep the mass units the same (1 g = 1000 mg, 1 mg = 1000 mcg).
答案: R = 9.3 mL/h
肝素和胰岛素输注:浓度 = 袋中单位数/袋容量 (units/mL)。泵速 (mL/h) = 每小时单位数/浓度,每小时单位数 = mL/h × 浓度。按体重给药时,先求 units/h = units/kg/h × 体重。推注体积 = 所需单位数/药瓶规格。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: R = 19.8 mL/h
滴定输注:先求以 mcg/mL 计的浓度(mg × 1000/mL)。按体重给药时,mcg/min = mcg/kg/min × 体重。然后 mL/h = mcg/min × 60/浓度。反推时,mcg/kg/min = mL/h × 浓度/(60 × 体重)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: U = 1.04 mL/kg/h
出入量:入量计入所有进入体内的液体(口服液体、静脉输液、静脉用药及冲管液、管饲);冰屑按其体积的一半计。出量计入尿液、引流液、呕吐物和其他丢失。平衡 = 总入量 − 总出量;平衡为负表示净丢失。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: t = 15.3 h
输液时间:时间 (h) = 待输体积 (mL)/速率 (mL/h);使用袋中剩余的体积,而不是袋的容量。已输入体积 = 速率 × 时间。把小数小时换算为小时和分钟时,用小数部分 × 60(0.5 h = 30 min,而不是 50 min)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
约为 15 h 20 min,所以袋子大约在 07:50 输完。
答案: B = 10
Braden 量表:评估压力性损伤风险的六个分项。感觉知觉、潮湿程度、活动、活动能力和营养各评 1 至 4 分,从最差水平(1)到无问题(4);摩擦力和剪切力评 1 至 3 分。总分为 6 至 23,总分越低风险越高。常用分级:19–23 无风险,15–18 轻度风险,13–14 中度风险,10–12 高风险,9 分及以下为极高风险。
答案: 中低
NEWS2(国家早期预警评分 2,英国皇家内科医师学会 2017):按图表为七个参数分别评分(呼吸频率、量表 1 的 SpO₂、吸空气还是吸氧、收缩压、脉搏、按 ACVPU 量表评定的意识状态和体温),然后把分数相加。临床风险:0–4 为低;任何单项参数得 3 分为中低;5–6 为中;7 或以上为高。总分 5 或以上需要紧急响应。
即使总分低,单项得 3 分也需要紧急会诊。
答案: HCO₃⁻ = 28.9 mmol/L
预期代偿:代谢性酸中毒时,温特公式预测 PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg;实测值高于该范围提示合并呼吸性酸中毒,低于该范围提示合并呼吸性碱中毒。阴离子间隙 AG = Na⁺ − (Cl⁻ + HCO₃⁻),正常约为 8–12 mmol/L,用于区分高阴离子间隙与正常阴离子间隙代谢性酸中毒;低白蛋白会掩盖升高的间隙(白蛋白低于 4.0 的部分,每 g/dL 加 2.5)。Δ 比值 (AG − 12)/(24 − HCO₃⁻) 约在 0.8 到 2 之间符合单纯高间隙酸中毒(有些教材用 1 代替 0.8),低于此范围提示合并正常间隙酸中毒,高于 2 提示合并代谢性碱中毒。
答案: 单纯高间隙酸中毒
预期代偿:代谢性酸中毒时,温特公式预测 PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg;实测值高于该范围提示合并呼吸性酸中毒,低于该范围提示合并呼吸性碱中毒。阴离子间隙 AG = Na⁺ − (Cl⁻ + HCO₃⁻),正常约为 8–12 mmol/L,用于区分高阴离子间隙与正常阴离子间隙代谢性酸中毒;低白蛋白会掩盖升高的间隙(白蛋白低于 4.0 的部分,每 g/dL 加 2.5)。Δ 比值 (AG − 12)/(24 − HCO₃⁻) 约在 0.8 到 2 之间符合单纯高间隙酸中毒(有些教材用 1 代替 0.8),低于此范围提示合并正常间隙酸中毒,高于 2 提示合并代谢性碱中毒。
答案: 一度房室传导阻滞
节律标准(II 导联):窦性心律每个 QRS 之前都有直立的 P 波,PR 恒定为 0.12–0.20 s,QRS 狭窄:60–100 次/分为正常窦性心律,低于 60 为窦性心动过缓,高于 100 为窦性心动过速。心房颤动:无 P 波,基线呈颤动,R–R 绝对不规则。心房扑动:约 250–350 次/分的锯齿状扑动波,伴固定的传导比例,如 2:1 或 4:1。一度房室传导阻滞:窦性心律,PR 恒定且大于 0.20 s。交界性心律:窄 QRS,40–60 次/分,P 波缺失或倒置(PR 低于 0.12 s,或 P 波在 QRS 之后)。室性早搏(PVC)是提前出现的宽大(0.12 s 或以上)、形态怪异的 QRS,没有 P 波,T 波方向相反,通常有完全性代偿间歇;二联律是指每隔一个搏动就有一个室性早搏。
答案: 2:1 房室传导阻滞(类型未定)
2:1 房室传导阻滞:每个 QRS 对应两个 P 波时,没有两个下传的 P 波连续出现,所以无法看出在未下传的 P 波之前,PR 间期是逐渐延长(I 型)还是保持恒定(II 型)。仅凭一条心电图条带,只能称为 2:1 房室传导阻滞;更长的条带或传导比例的改变才能决定类型。QRS 较窄时更可能是 I 型,QRS 增宽时更可能是 II 型,但两者都不能证明。
QRS 较窄时更可能是 I 型,QRS 增宽时更可能是 II 型,但只有更长的条带或传导比例的改变才能决定。
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