感染控制与患者安全
方法
- 对每位患者都从标准预防开始:手卫生、针对预期暴露的个人防护装备、安全使用锐器。
- 按传播途径追加预防措施:接触传播(隔离衣、手套)、飞沫传播(外科口罩)、空气传播(N95、负压病房)。
- 保持无菌物品的无菌状态:如有疑问就视为不无菌;更换,绝不擦拭。
- 预防环境中的伤害:防跌倒措施,约束仅作为最后手段,火灾时用 RACE 和 PASS。
- 核对给药的正确原则、两个身份识别信息,以及对高警示药物的额外保障;报告差错和险兆事件。
公式表、每个专题的关键方法步骤和 40 道练习题,完整解答附在最后。
护士在什么情况下可以未经患者同意分享保密信息?
一名护士被用过的针头刺伤。正确的第一步处理是什么?
A patient with delirium is at risk of falls and of pulling out lines. Which option is less restrictive than restraints?
While preparing a chemotherapy infusion, the drug splashes onto a nurse’s forearm. What should the nurse do first?
一名患者突然流鼻血,意识清醒,呼吸正常。护士首先做什么?
A charge nurse notices that a nurse smells of alcohol and is slurring words at the start of the shift. What is the priority?
A patient with Guillain–Barré syndrome has weakness spreading upwards from the legs. Which monitoring is most important?
A patient has a full-thickness burn all the way round the forearm. Which complication must be watched for closely?
In the US, when is a pregnant woman without known risk factors usually screened for gestational diabetes?
A patient in hyperosmolar hyperglycemic state has a glucose of 1,050 mg/dL (58 mmol/L), very dry mucous membranes and a fast pulse. Which treatment is usually the first priority?
A patient is starting lisinopril. Which rare but serious adverse effect should the nurse teach the patient to report immediately?
A patient with diabetic ketoacidosis is about to start an IV insulin infusion. Serum potassium is 3.1 mmol/L (mEq/L). Why is this a concern?
A patient with chest pain has a first troponin result within the normal range one hour after the pain started. Why is a repeat test arranged?
一名胸痛患者的 II、III 和 aVF 导联 ST 段抬高。血压 86/54 mmHg,肺部清晰,颈静脉怒张。护士应对哪种处方药提出疑问?
What is the main purpose of continuous bladder irrigation after a transurethral resection of the prostate (TURP)?
A patient with lung cancer is confused, dehydrated and constipated, with a corrected calcium of 3.4 mmol/L (about 13.6 mg/dL). What is usually the first treatment?
许多化疗药物给药后,对体液采取特殊预防措施通常要持续多长时间?
通过外周套管针静脉输注长春新碱时,患者报告灼痛,输注部位肿胀。护士首先应做什么?
A woman at 10 weeks has morning sickness. Which suggestion is most likely to help?
在产后病房,哪项发现应立即上报?
What is the main purpose of medical play with a doll and real equipment before surgery?
A family with a 2-year-old has a swimming pool in the garden. Which measure gives the most protection against drowning?
What is the Abnormal Involuntary Movement Scale (AIMS) used for?
Verbal de-escalation has failed, and a patient picks up a chair and threatens to throw it at the nurse. What should the nurse do first?
练习题(虚构数值,不作为临床指导)。 一位患者的体温为 96.5 °F。用 °C = (°F − 32) × 5/9 把它换算为摄氏度T。取到一位小数。
练习题(虚构数值,不作为临床指导)。 一次输注从 18:35 开始,到次日早晨 01:50 结束(24 小时制)。它运行了多少分钟t?
一名体重 10 kg 的儿童按 5 mg/kg 处方用药。原液浓度为 25 mg/mL。请抽取剂量:应给多少体积 V?
处方剂量为 235 微克。安瓿浓度为 0.5 mg/mL。请用 1 mL 注射器抽取剂量:应给多少体积 V?
用滴系数为 20 滴/mL 的输液器在 12 小时内输入 1500 mL。求滴速 R(滴/分)。 取整到最接近的整数。
50 mg 药物溶于 250 mL 的输液以 12 mL/h 运行。患者每分钟接受多少微克 D?
练习题(虚构数值,不作为临床指导)。 一项练习规程要求为体重 73 kg 的患者推注肝素 70 units/kg。药瓶规格为 5 000 units/mL。应抽取多少体积 V? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 一袋中含dopamine 800 mg,容量 500 mL。医嘱为 5 mcg/kg/min,患者体重 66 kg。输液泵速率 R 应设为多少 mL/h? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 记录显示了一名患者在一个 12 小时班次中的出入量。静脉输液在整个班次中按所示速率输注。求液体平衡 B = 入量 − 出量,以 mL 计(答案为负表示净丢失)。
练习题(虚构数值,不作为临床指导)。 一袋 1000 mL 的液体用输液泵以 60 mL/h 输注。到 09:30 时已输入 400 mL。还要多少小时 t 袋子才会输完? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 一位患者的脉搏为 121 次/分,血压为 102/66 mmHg。求休克指数SI = HR/SBP。取到两位小数。
练习题(虚构数值,不作为临床指导)。 一名成人体重 118 kg,身高 170 cm。计算 BMI 并点击 WHO 体重分类。
某练习血气显示代谢性酸中毒,HCO₃⁻ 14 mmol/L。用温特公式求预期PaCO₂(范围的中心),单位 mmHg。
某练习血气显示呼吸性酸中毒:pH 7.27,PaCO₂ 70 mmHg (9.3 kPa),HCO₃⁻ 31 mmol/L。利用规则“HCO₃⁻ 每 10 mmHg 升高 1 mmol/L(急性)或 3.5 mmol/L(慢性)”进行分类。点选你的答案。
在这条规则的 II 导联心电图上测量 QT 间期和 R–R 间期,然后用 Bazett 公式 QTc = QT/√RR(均以秒计)计算经心率校正的QTc。答案以秒表示,保留三位小数。
请解读这条 II 导联心电图条带。仅凭这一条心电图条带,你能为哪种解读辩护?点击你的答案。
答案: D · 为保护某人免受严重伤害的风险而有必要时
在法律要求或患者及他人面临严重伤害风险时,可以未经同意打破保密。只与适当的人分享必要的信息。
答案: A · 让伤口自然出血,用肥皂和流动水冲洗,然后立即报告
急救处理是让伤口自然出血而不挤压,用肥皂和流动水冲洗并覆盖,不要擦洗或吸吮。立即报告便于进行风险评估,并在需要时进行暴露后预防。
答案: A · A trained sitter or video monitoring with staff nearby
Close observation by a sitter or video monitoring allows staff to step in quickly, without restricting the patient. It is often combined with reorientation and family presence.
答案: C · Remove contaminated PPE and wash the skin with soap and water at once
Skin exposure to hazardous drugs is washed immediately with soap and water after removing contaminated gloves or gown. The exposure is then reported and treated according to policy.
答案: C · 让患者坐起,身体前倾,并捏住鼻子的软骨部分
身体前倾可使血液不进入气道和胃,用力捏住鼻子的软骨部分通常可止血。头后仰或平躺会使血液流入咽喉。
答案: D · Remove the nurse from patient care and report it according to policy
A nurse who appears impaired must not care for patients. The charge nurse removes them from duty and follows policy for reporting; support, such as an assistance program, can follow.
答案: A · Breathing function, such as forced vital capacity
Guillain–Barré syndrome can paralyse the respiratory muscles. Serial vital capacity measurements help identify patients who need ventilation before they deteriorate.
答案: D · Loss of circulation to the hand as swelling builds under tight burned skin
Circumferential full-thickness burns form a tight eschar that acts like a tourniquet as oedema develops. Neurovascular checks are needed, and escharotomy may be required.
答案: B · At about 24–28 weeks of pregnancy
Placental hormones increase insulin resistance in the second half of pregnancy, so US guidance recommends screening all women at 24–28 weeks, with earlier testing for those with risk factors. In the UK, NICE recommends an oral glucose tolerance test at 24–28 weeks only for women with risk factors.核对依据: Glucose screening tests during pregnancy · MedlinePlus (NIH) (2026); Gestational diabetes · MedlinePlus (NIH) (2026)
答案: B · Large-volume IV fluid replacement
In HHS the fluid deficit is often very large, so IV fluid replacement is the first priority; it also lowers the glucose. Insulin follows as prescribed, and potassium, sodium and mental status are monitored closely.核对依据: Diabetic hyperglycemic hyperosmolar syndrome · MedlinePlus (NIH) (2026)
答案: C · Swelling of the lips, tongue or face
ACE inhibitors can cause angioedema, which can obstruct the airway and needs emergency care. It is linked to raised bradykinin levels and can occur even after long use.
答案: D · Insulin moves potassium into cells, so the level can fall dangerously low
Insulin drives potassium into cells, so a low starting level can become life-threatening hypokalaemia with arrhythmias. Potassium is replaced and monitored closely; the 2024 international consensus (ADA and others) delays insulin until potassium is above 3.5 mmol/L, while UK JBDS guidance adds potassium to the fluids and asks for senior review.
答案: A · Troponin may take a few hours to rise after muscle damage
Troponin starts to rise within hours of myocardial injury, so a very early result can be normal. Protocols use serial measurements at set intervals, with the ECG and clinical picture, to diagnose or exclude MI. A rising pattern supports acute injury.
答案: B · 舌下含服硝酸甘油(glyceryl trinitrate)
下壁 STEMI 伴低血压、颈静脉压升高且肺部清晰,提示右心室梗死。这些患者依赖前负荷,硝酸酯类可引起严重低血压;收缩压低于 90 mmHg 本身就是暂停使用的理由。阿司匹林仍有指征,紧急再灌注才是根本治疗。
答案: D · To stop blood clots from blocking the catheter
After TURP, the raw prostate bed bleeds, and clots can block the catheter and cause retention and bladder spasms. Continuous irrigation through a three-way catheter keeps the drainage flowing.
答案: A · IV fluids to rehydrate the patient
Hypercalcaemia causes polyuria and dehydration, which worsen the high calcium. IV fluids are the first step, followed by a bisphosphonate to reduce bone resorption. Calcium is rechecked regularly.
答案: C · 通常约 48 小时
许多细胞毒性药物在给药后的一段时间内会经尿、粪、呕吐物和其他体液排出。当地规定通常要求处理体液时戴手套和穿隔离衣约 48 小时,某些药物需要更长时间。
答案: B · 停止输注,保留套管针以回抽,并遵循规程
发疱剂外渗可造成严重的组织损伤。应立即停止输注,尝试通过套管针回抽药物,然后遵循具体规程(长春碱类如长春新碱通常采用热敷,可能使用透明质酸酶,而蒽环类药物通常采用冷敷),抬高肢体,记录并通知团队。
答案: B · Eat dry crackers before rising and eat small meals
Eating something dry before rising, small frequent meals, and drinking fluids between rather than with meals reduce nausea. Fatty and spicy foods tend to worsen it.
答案: B · 产妇在 15 分钟内浸透一大块卫生垫
15 分钟内浸透一块卫生垫属于出血过多,需要立即评估并上报。其他发现在产后早期都是正常的。
答案: B · To let the child express fears and gain a sense of control
Therapeutic or medical play lets children explore equipment, act out procedures and show feelings they cannot put into words. It reduces anxiety and helps staff correct misunderstandings.
答案: B · A four-sided fence with a self-closing, self-latching gate, plus constant supervision
Isolation fencing that fully separates the pool from the house and garden, combined with active adult supervision, is the most effective protection. Flotation aids and lessons do not replace supervision, and toddlers cannot reliably follow safety rules.
答案: B · To screen for and monitor tardive dyskinesia
The AIMS is a structured examination of involuntary movements of the face, limbs and trunk. It is done at baseline and regularly during long-term antipsychotic treatment so tardive dyskinesia is detected early.
答案: C · Keep a safe distance, call for help and avoid trying to take the chair alone
When a patient is imminently violent, the nurse protects herself and others, keeps an exit route and summons a trained team. Acting alone risks injury to everyone involved.
答案: T = 35.8 °C
温度:°C = (°F − 32) × 5/9,°F = °C × 9/5 + 32。从 °F 换算时先减 32 再乘,从 °C 换算时先乘再加 32。快速核对:37 °C 为 98.6 °F,每 1 °C 相当于 1.8 °F。
答案: t = 435 min
24 小时制:下午 1 点起,小时数加 12(下午 3:45 = 15:45)。午夜到凌晨 12:59 为 00:00–00:59,中午 12:00–12:59 仍为 12:00–12:59。反过来换算时,13–23 点减 12 并标为下午;00 点变为凌晨 12 点。跨午夜计算时间要分两段:先算到 24:00(00:00),再从 00:00 算起。
答案: V = 2 mL
抽取剂量:体积 = (处方剂量/药物浓度) × 药物体积。先换算成相同的单位,再检查该体积是否适合注射器,并落在它的某一个刻度上。
在这支 10 mL 的注射器上,每条小刻度线代表 0.2 mL。
答案: V = 0.47 mL
抽取剂量:体积 = (处方剂量/药物浓度) × 药物体积。先换算成相同的单位,再检查该体积是否适合注射器,并落在它的某一个刻度上。
答案: R = 42 gtt/min
输注速率:输液泵按 mL/h = 体积/时间(小时)设定。重力滴注按每分钟滴数计:gtt/min = 体积 (mL) × 滴系数 (gtt/mL)/时间 (min)。 滴系数印在输液器包装上:普通输液器为 10、15 或 20 gtt/mL(输血器在美国常为 10 gtt/mL,在英国为 15),微量输液器为 60 gtt/mL。务必使用题目或包装给出的滴系数。
床旁取最接近的整滴:42 滴/分。
答案: D = 40 mcg/min
Dose-based infusions: concentration = amount of drug in the bag/bag volume. Pump rate (mL/h) = dose per hour/concentration, and dose per hour = mL/h × concentration. Convert per-minute doses to per-hour (× 60) and keep the mass units the same (1 g = 1000 mg, 1 mg = 1000 mcg).
答案: V = 1 mL
肝素和胰岛素输注:浓度 = 袋中单位数/袋容量 (units/mL)。泵速 (mL/h) = 每小时单位数/浓度,每小时单位数 = mL/h × 浓度。按体重给药时,先求 units/h = units/kg/h × 体重。推注体积 = 所需单位数/药瓶规格。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: R = 12.4 mL/h
滴定输注:先求以 mcg/mL 计的浓度(mg × 1000/mL)。按体重给药时,mcg/min = mcg/kg/min × 体重。然后 mL/h = mcg/min × 60/浓度。反推时,mcg/kg/min = mL/h × 浓度/(60 × 体重)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: B = −75 mL
出入量:入量计入所有进入体内的液体(口服液体、静脉输液、静脉用药及冲管液、管饲);冰屑按其体积的一半计。出量计入尿液、引流液、呕吐物和其他丢失。平衡 = 总入量 − 总出量;平衡为负表示净丢失。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
为负:患者丢失的液体多于摄入的液体。
答案: t = 10 h
输液时间:时间 (h) = 待输体积 (mL)/速率 (mL/h);使用袋中剩余的体积,而不是袋的容量。已输入体积 = 速率 × 时间。把小数小时换算为小时和分钟时,用小数部分 × 60(0.5 h = 30 min,而不是 50 min)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
约为 10 h 00 min,所以袋子大约在 19:30 输完。
答案: SI = 1.19
血压数值:脉压 PP = SBP − DBP。平均动脉压 MAP ≈ (SBP + 2·DBP)/3 = DBP + PP/3,这是基于正常心率下心脏每搏约有三分之二时间处于舒张期的估算(心率快时准确性下降);MAP 至少约 65 mmHg 是常用的器官灌注目标。休克指数 SI = 心率/SBP,正常约为 0.5–0.7;高于约 1 是休克的警示信号。
1 或更高:在这个练习病例中是休克的警示信号。
答案: 肥胖 III 级
体质指数:BMI = 体重(kg)/身高(m)²,身高要先换算为米。使用磅和英寸时,BMI = 703 × 体重(lb)/身高(in)²。WHO 成人分类:低于 18.5 为体重过轻,18.5–24.9 为健康体重,25.0–29.9 为超重,30.0–34.9 为肥胖 I 级,35.0–39.9 为肥胖 II 级,40 及以上为肥胖 III 级。
答案: PaCO₂ = 29 mmHg
预期代偿:代谢性酸中毒时,温特公式预测 PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg;实测值高于该范围提示合并呼吸性酸中毒,低于该范围提示合并呼吸性碱中毒。阴离子间隙 AG = Na⁺ − (Cl⁻ + HCO₃⁻),正常约为 8–12 mmol/L,用于区分高阴离子间隙与正常阴离子间隙代谢性酸中毒;低白蛋白会掩盖升高的间隙(白蛋白低于 4.0 的部分,每 g/dL 加 2.5)。Δ 比值 (AG − 12)/(24 − HCO₃⁻) 约在 0.8 到 2 之间符合单纯高间隙酸中毒(有些教材用 1 代替 0.8),低于此范围提示合并正常间隙酸中毒,高于 2 提示合并代谢性碱中毒。
答案: 慢性基础上的急性
预期代偿:代谢性酸中毒时,温特公式预测 PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg;实测值高于该范围提示合并呼吸性酸中毒,低于该范围提示合并呼吸性碱中毒。阴离子间隙 AG = Na⁺ − (Cl⁻ + HCO₃⁻),正常约为 8–12 mmol/L,用于区分高阴离子间隙与正常阴离子间隙代谢性酸中毒;低白蛋白会掩盖升高的间隙(白蛋白低于 4.0 的部分,每 g/dL 加 2.5)。Δ 比值 (AG − 12)/(24 − HCO₃⁻) 约在 0.8 到 2 之间符合单纯高间隙酸中毒(有些教材用 1 代替 0.8),低于此范围提示合并正常间隙酸中毒,高于 2 提示合并代谢性碱中毒。
答案: QTc = 0.469 s
QT 与 QTc:QT 间期从 QRS 波群起点到 T 波终点。它随心率加快而缩短,因此要用以秒为单位的 R–R 间期按心率校正:Bazett QTc = QT/√RR,Fridericia QTc = QT/∛RR。多数教科书使用 Bazett 公式;它在心率快时校正过度,此时宜用 Fridericia。各参考标准的界限不同:QTc 男性高于约 0.45 s、女性高于约 0.46 s 通常称为延长,高于 0.50 s 称为明显延长。
超过男性(约 0.45 s)和女性(约 0.46 s)的通常上限:延长。(469 ms)
答案: 2:1 房室传导阻滞(类型未定)
2:1 房室传导阻滞:每个 QRS 对应两个 P 波时,没有两个下传的 P 波连续出现,所以无法看出在未下传的 P 波之前,PR 间期是逐渐延长(I 型)还是保持恒定(II 型)。仅凭一条心电图条带,只能称为 2:1 房室传导阻滞;更长的条带或传导比例的改变才能决定类型。QRS 较窄时更可能是 I 型,QRS 增宽时更可能是 II 型,但两者都不能证明。
QRS 较窄时更可能是 I 型,QRS 增宽时更可能是 II 型,但只有更长的条带或传导比例的改变才能决定。
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