感染控制与患者安全
方法
- 对每位患者都从标准预防开始:手卫生、针对预期暴露的个人防护装备、安全使用锐器。
- 按传播途径追加预防措施:接触传播(隔离衣、手套)、飞沫传播(外科口罩)、空气传播(N95、负压病房)。
- 保持无菌物品的无菌状态:如有疑问就视为不无菌;更换,绝不擦拭。
- 预防环境中的伤害:防跌倒措施,约束仅作为最后手段,火灾时用 RACE 和 PASS。
- 核对给药的正确原则、两个身份识别信息,以及对高警示药物的额外保障;报告差错和险兆事件。
公式表、每个专题的关键方法步骤和 40 道练习题,完整解答附在最后。
A patient says, "I've never seen this tablet before," as the nurse offers it. What should the nurse do?
A small fire starts in a patient's room. What is the first action?
A woman who is pregnant asks for the MMR vaccine because she is not immune to rubella. What is correct?
A nurse asks a colleague to “just glance” at an insulin infusion before starting it. What makes a check truly independent?
A patient on a medical unit tells the nurse he has a plan to end his life and has saved tablets at home. What is the priority action?
A patient takes lithium. Which statement shows a need for further teaching?
Compared with a colostomy, a patient with an ileostomy is at greater risk of:
A patient has a swollen, warm, tender calf on one side. Which action should the nurse avoid?
A patient with type 2 diabetes starts prednisone each morning. When is the glucose most likely to be highest?
At the start of a shift, the nurse reviews four new results. Which patient needs attention first?
Which lab tests are monitored in a patient taking carbamazepine?
某药分布容积为 40 L,生物利用度为 100%。要达到 2 mg/L 的目标血浆浓度,负荷剂量应为多少?
A patient has episodes of severe headache, sweating and palpitations with very high blood pressure. Which rare cause should be considered?
Hours after surgery to restore blood flow to an ischaemic leg, the patient has severe calf pain that is worse when the toes are moved passively, and the calf feels tense. What should the nurse suspect?
Which group of problems is typical of primary hyperparathyroidism?
A patient with Guillain–Barré syndrome has a blood pressure that swings between 80/50 and 190/100 mmHg and a heart rate that changes suddenly. What does this suggest?
A patient had an upper GI endoscopy with a local anaesthetic throat spray. What must the nurse check before giving a drink?
A nurse finds a dislodged sealed radiation source in the bed of a patient receiving brachytherapy. What should the nurse do?
Why is tight glucose control before conception important in women with pre-existing diabetes?
A woman on day 2 after a caesarean suddenly has chest pain, breathlessness, a heart rate of 120/min and an oxygen saturation of 90%. What is the priority?
10 个月婴儿的哪项生长曲线表现最需要进一步评估?
手术后,一名 4 岁儿童一动不动地躺着,做鬼脸,腿部紧绷并呻吟。FLACC 评分为 8 分。护士应怎么做?
一名患者说:“我要吃药丸、账单、山丘、蒸馏器。”(I'll take the pill, the bill, the hill, the still.)这称为什么?
一名患者来回踱步,攥紧拳头,并对工作人员大喊大叫。最恰当的首要应对方式是什么?
练习题(虚构数值,不作为临床指导)。 一位患者身高 5 ft 1 in。按 1 ft = 12 in 和 1 in = 2.54 cm,求以厘米表示的身高h,取到最接近的整厘米。
练习题(虚构数值,不作为临床指导)。 一张处方写着口服混悬液1 tsp,每 8 小时一次,共 5 天。按1 tsp = 5 mL,整个疗程需要多少 mLV?
某患者体重 45 kg,医嘱为单次给药 20 mg/kg。求剂量 D(mg)。
处方剂量为 65 微克。安瓿浓度为 0.5 mg/mL。请用 1 mL 注射器抽取剂量:应给多少体积 V?
医嘱要求以 90 mL/h 输液,但没有输液泵。改用滴系数为 60 gtt/mL 的输液器重力滴注。求滴速 R,以每分钟滴数表示。
一袋液体在 50 mL 中含药 200 mg,以 8 mL/h 的速度输注。患者每小时获得多少毫克 D?
练习题(虚构数值,不作为临床指导)。 一袋中含肝素 25 000 单位,容量 500 mL。医嘱为 18 units/kg/h,患者体重 73 kg。输液泵速率 R 应设为多少 mL/h? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 一名体重 64 kg 的患者的医嘱为norepinephrine 10 mcg/min。输液袋中含 8 mg,容量 250 mL。求泵速 R,以 mL/h 计。 保留一位小数。
练习题(虚构数值,不作为临床指导)。 记录显示了一名患者在一个 12 小时班次中的出入量。患者体重 46 kg。求平均尿量 U,以 mL/kg/h 计。 保留两位小数。
练习题(虚构数值,不作为临床指导)。 一袋 1000 mL 的液体于 12:15 开始用输液泵以 120 mL/h 输注。到 19:45 时袋中还剩多少 mL V?
练习题(虚构数值,不作为临床指导)。 一位患者的脉搏为 104 次/分,血压为 85/51 mmHg。求休克指数SI = HR/SBP。取到两位小数。
练习题(虚构数值,不作为临床指导)。 一名成人体重 139 kg,身高 195 cm。计算 BMI 并点击 WHO 体重分类。
练习数值:Na⁺ 150 mmol/L,葡萄糖 16 mmol/L,尿素 23 mmol/L。计算血清渗透压 Osm = 2·Na⁺ + 葡萄糖 + 尿素,取最接近的整数。
在海平面,某练习血气取自吸入 40% 氧气时,显示 PaO₂ 50 mmHg (6.7 kPa),PaCO₂ 41 mmHg (5.5 kPa)。用 PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 求A–a 梯度。
解读这条 II 导联心律条带。这是什么节律?点击你的答案。
依次按五个步骤解读这条 II 导联心电图:心率、节律、P 波、PR 间期、QRS 时限。你在哪一步发现第一个异常?点击它。
答案: D · Stop and recheck the prescription before giving it
A patient questioning a medicine may be a sign of an error. The nurse holds the dose, checks the prescription and the drug and explains before giving it.
答案: A · Move the patient away from immediate danger
The first priority is to rescue anyone in immediate danger, then raise the alarm, contain the fire by closing doors and only then try to extinguish it if safe. Opening windows feeds a fire with oxygen.
答案: C · MMR is a live vaccine and is not given during pregnancy, but can be given after delivery
Live vaccines such as MMR and varicella are not given during pregnancy. A non-immune woman is vaccinated after delivery, and pregnancy is avoided for a period after vaccination.
答案: D · The second nurse checks the order, drug, dose and pump settings separately without being told the answer
In an independent double check, the second person works through each step on their own, then the two results are compared. Reading the answer aloud or glancing invites confirmation bias.
答案: B · Ensure constant observation and remove anything he could use to harm himself
A patient with a plan and means is at high risk. Safety comes first: constant observation, removal of means and urgent referral. A “no-harm promise” does not protect the patient.
答案: B · “I will take ibuprofen every day for my headaches.”
NSAIDs such as ibuprofen can raise lithium levels and cause toxicity. Steady fluid and salt intake and regular blood tests help keep levels safe.
答案: C · Dehydration and electrolyte loss from liquid output
Ileostomy output is liquid because it bypasses the colon, which normally absorbs water and salts. Patients must drink enough and watch for signs of dehydration, especially in hot weather or illness.
答案: B · Massaging the calf
Unilateral calf swelling and tenderness suggests DVT. Massaging the leg is avoided in case it dislodges the clot; the patient needs medical review and investigation.
答案: D · In the afternoon and evening
A morning dose of prednisone raises glucose mainly in the afternoon and evening, with a smaller effect overnight. Glucose monitoring and insulin plans often target these times, and doses are adjusted when the steroid is tapered.核对依据: Blood Glucose Test · MedlinePlus (NIH) (2024)
答案: A · Sodium 119 mEq/L in a patient with new confusion and vomiting
Severe hyponatremia with confusion and vomiting suggests cerebral edema and can progress to seizures and coma. The other results are mildly abnormal and expected for those conditions, so they are less urgent.核对依据: Low blood sodium - Medical Encyclopedia · MedlinePlus (NIH) (2025); Sodium Blood Test · MedlinePlus (NIH) (2024)
答案: A · Full blood count and serum sodium
Carbamazepine can rarely cause bone marrow suppression and commonly lowers serum sodium. Blood counts, sodium and liver tests are checked, especially early in treatment.
答案: D · 80 mg
负荷剂量 = 40 L × 2 mg/L = 80 mg。负荷剂量取决于 Vd,而维持剂量取决于清除率。
答案: C · Phaeochromocytoma
Phaeochromocytoma is a catecholamine-secreting tumour, usually of the adrenal medulla. Classic features are paroxysmal headache, sweating, palpitations and hypertension. It is diagnosed with plasma or urine metanephrines.
答案: D · Compartment syndrome from reperfusion swelling
When blood flow returns to ischaemic muscle, swelling can raise pressure in a fascial compartment. Pain out of proportion and pain on passive stretch are early signs; pulses may remain until late. It is reported urgently, as fasciotomy may be needed. The limb is kept at heart level, not raised high.
答案: C · Kidney stones, bone pain, abdominal pain and low mood
High PTH raises calcium, which can cause kidney stones, bone loss and pain, constipation and abdominal pain, and low mood or confusion ("stones, bones, groans and moans"). Many cases are found on routine blood tests.
答案: A · Autonomic dysfunction, which needs continuous cardiac monitoring
Guillain–Barré syndrome can involve autonomic nerves, causing labile blood pressure and dangerous arrhythmias. Patients need continuous ECG monitoring and close observation, often in a high-dependency setting.
答案: C · That swallowing and the gag reflex have returned
Throat spray numbs the pharynx, so drinking too early risks aspiration. Fluids are given once the gag reflex and swallowing have returned, usually after about an hour, starting with sips of water.
答案: D · Use long-handled forceps to put it in the lead container; report it
A dislodged source is picked up with long-handled forceps and placed in the shielded container kept in the room. The radiation safety officer and team are informed, following local policy.
答案: B · Early hyperglycaemia raises the risk of birth defects
Hyperglycaemia during organogenesis increases the risk of heart, neural tube and other anomalies and of miscarriage. Good preconception control and high-dose folic acid lower this risk.
答案: A · Call for help, sit her up and give oxygen
Sudden breathlessness, chest pain, tachycardia and hypoxia suggest pulmonary embolism, a leading cause of maternal death. The nurse calls for urgent help, positions her upright, gives oxygen and prepares for investigations and anticoagulation.
答案: D · 自上几次就诊以来,体重已跨越两条主要百分位线下降
沿着较低百分位稳步生长的儿童可能只是个子小。跨越两条主要百分位线提示生长迟缓,需要评估喂养、疾病和社会状况。
答案: B · 给予处方的镇痛药,并在药物起效后重新评估疼痛
FLACC 评分 7–10 分表示重度疼痛。应给予处方的镇痛药,同时采用安抚措施,并在适当的时间重新评估效果。
答案: A · 音联联想(clang association)
音联联想以押韵或声音联系词语,见于躁狂和精神病。模仿言语是重复他人的话;新语症是新创造的词。
答案: A · 用平静的语言降级处理,保持安全距离,并确保双方都有出口
降级处理使用平静的声音、简单的语言、积极倾听和提供选择,同时保持安全距离和退路。如果存在迫在眉睫的危险,约束才是最后的手段。
答案: h = 155 cm
家用计量和体重:护理考试使用取整的等量关系:1 茶匙(tsp)= 5 mL,1 汤匙(tbsp)= 15 mL = 3 tsp,1 液量盎司(fl oz)= 30 mL = 2 tbsp,1 杯 = 8 fl oz = 240 mL。体重方面,1 kg = 2.2 lb,1 lb = 16 oz;长度方面,1 英寸 = 2.54 cm。设置换算时,要让你不需要的单位相互约去。
答案: V = 75 mL
量纲分析:先写出已知量,再乘以写成分数形式的换算系数(例如 60 min/1 h 或 1 mg/1000 mcg),使每个不需要的单位在分子和分母各出现一次并相互约去。只剩下所求单位时再计算。使用题目给出的等量关系,只对最终答案取整。
答案: D = 900 mg
剂量计算:给药量等于医嘱剂量除以现有药物的规格,再乘以该规格对应的量:给药量 = (医嘱剂量/储备规格) × 储备体积。始终统一单位(先把 g 换成 mg,mg 换成 mcg),并检查答案是否合理。
答案: V = 0.13 mL
抽取剂量:体积 = (处方剂量/药物浓度) × 药物体积。先换算成相同的单位,再检查该体积是否适合注射器,并落在它的某一个刻度上。
答案: R = 90 gtt/min
Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.
使用微滴输液器(60 gtt/mL)时,gtt/min 等于 mL/h。
答案: D = 32 mg/h
输注速率:输液泵按 mL/h = 体积/时间(小时)设定。重力滴注按每分钟滴数计:gtt/min = 体积 (mL) × 滴系数 (gtt/mL)/时间 (min)。 滴系数印在输液器包装上:普通输液器为 10、15 或 20 gtt/mL(输血器在美国常为 10 gtt/mL,在英国为 15),微量输液器为 60 gtt/mL。务必使用题目或包装给出的滴系数。
答案: R = 26.3 mL/h
肝素和胰岛素输注:浓度 = 袋中单位数/袋容量 (units/mL)。泵速 (mL/h) = 每小时单位数/浓度,每小时单位数 = mL/h × 浓度。按体重给药时,先求 units/h = units/kg/h × 体重。推注体积 = 所需单位数/药瓶规格。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: R = 18.8 mL/h
滴定输注:先求以 mcg/mL 计的浓度(mg × 1000/mL)。按体重给药时,mcg/min = mcg/kg/min × 体重。然后 mL/h = mcg/min × 60/浓度。反推时,mcg/kg/min = mL/h × 浓度/(60 × 体重)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
医嘱是针对患者整体的每分钟剂量,所以不需要体重。
答案: U = 1.81 mL/kg/h
出入量:入量计入所有进入体内的液体(口服液体、静脉输液、静脉用药及冲管液、管饲);冰屑按其体积的一半计。出量计入尿液、引流液、呕吐物和其他丢失。平衡 = 总入量 − 总出量;平衡为负表示净丢失。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: V = 100 mL
输液时间:时间 (h) = 待输体积 (mL)/速率 (mL/h);使用袋中剩余的体积,而不是袋的容量。已输入体积 = 速率 × 时间。把小数小时换算为小时和分钟时,用小数部分 × 60(0.5 h = 30 min,而不是 50 min)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: SI = 1.22
血压数值:脉压 PP = SBP − DBP。平均动脉压 MAP ≈ (SBP + 2·DBP)/3 = DBP + PP/3,这是基于正常心率下心脏每搏约有三分之二时间处于舒张期的估算(心率快时准确性下降);MAP 至少约 65 mmHg 是常用的器官灌注目标。休克指数 SI = 心率/SBP,正常约为 0.5–0.7;高于约 1 是休克的警示信号。
1 或更高:在这个练习病例中是休克的警示信号。
答案: 肥胖 II 级
体质指数:BMI = 体重(kg)/身高(m)²,身高要先换算为米。使用磅和英寸时,BMI = 703 × 体重(lb)/身高(in)²。WHO 成人分类:低于 18.5 为体重过轻,18.5–24.9 为健康体重,25.0–29.9 为超重,30.0–34.9 为肥胖 I 级,35.0–39.9 为肥胖 II 级,40 及以上为肥胖 III 级。
答案: Osm = 339 mOsm/kg
衍生数值:计算所得的血清渗透压为 2·Na⁺ + 葡萄糖 + 尿素,各值均以 mmol/L 计(葡萄糖和 BUN 以 mg/dL 计时为 2·Na⁺ + 葡萄糖/18 + BUN/2.8);正常约为 275–295 mOsm/kg。P/F 比值是 PaO₂ 除以以小数表示的 FiO₂。海平面的肺泡氧分压为 PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg,A–a 梯度为 PAO₂ − PaO₂。
答案: A–a 梯度 = 183.9 mmHg
衍生数值:计算所得的血清渗透压为 2·Na⁺ + 葡萄糖 + 尿素,各值均以 mmol/L 计(葡萄糖和 BUN 以 mg/dL 计时为 2·Na⁺ + 葡萄糖/18 + BUN/2.8);正常约为 275–295 mOsm/kg。P/F 比值是 PaO₂ 除以以小数表示的 FiO₂。海平面的肺泡氧分压为 PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg,A–a 梯度为 PAO₂ − PaO₂。
答案: 窦性心律伴窦性停搏
节律标准(II 导联):窦性心律每个 QRS 之前都有直立的 P 波,PR 恒定为 0.12–0.20 s,QRS 狭窄:60–100 次/分为正常窦性心律,低于 60 为窦性心动过缓,高于 100 为窦性心动过速。心房颤动:无 P 波,基线呈颤动,R–R 绝对不规则。心房扑动:约 250–350 次/分的锯齿状扑动波,伴固定的传导比例,如 2:1 或 4:1。一度房室传导阻滞:窦性心律,PR 恒定且大于 0.20 s。交界性心律:窄 QRS,40–60 次/分,P 波缺失或倒置(PR 低于 0.12 s,或 P 波在 QRS 之后)。室性早搏(PVC)是提前出现的宽大(0.12 s 或以上)、形态怪异的 QRS,没有 P 波,T 波方向相反,通常有完全性代偿间歇;二联律是指每隔一个搏动就有一个室性早搏。 窄 QRS 心动过速与停顿:室上性心动过速(SVT)是规则的心动过速,约 150–250 次/分钟,QRS 波群较窄;P 波通常看不到,因为它们隐藏在 QRS 波群或 T 波中。成人静息时的窦性心动过速通常低于约 150 次/分钟,且每个 QRS 前都有可见的 P 波;伴 2:1 传导的心房扑动常在约 150 次/分钟,并显示锯齿波。窦性停搏是指窦房结暂时停止发放冲动:出现既无 P 波也无 QRS 的停顿,其长度不是 P–P 周期的整数倍(恰好两个或三个周期的停顿则提示窦房传导阻滞)。
答案: 节律
每条心电图的五个步骤:1. 心率(300 法或 1500 法;若不规则则用 6 秒法);2. 节律:R–R 间期是否相等;3. P 波:是否存在、在 II 导联直立、每个 QRS 之前各有一个且形态一致;4. PR 间期:0.12–0.20 s 且恒定;5. QRS 时限:低于 0.12 s。五个步骤做完之后才命名节律。正常窦性心律五项全部符合:60–100 次/分,规则,每个 QRS 之前有直立 P 波,PR 0.12–0.20 s,QRS 低于 0.12 s。
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