1.简单
Tamoxifen is used mainly to treat:
- AOsteoarthritis
- BOestrogen receptor-positive breast cancer
- CProstate enlargement and prostate cancer in older men
- DType 2 diabetes
2.简单
Infliximab and adalimumab are biological drugs that block:
- AVitamin K recycling
- BTumour necrosis factor-alpha (TNF-alpha)
- CInsulin receptors
- DHistamine H1 receptors in the skin and airways
3.简单
Why is methadone used to treat opioid use disorder?
- AIt is a pure opioid antagonist that blocks all opioid effects
- BIt cures the liver damage caused by opioids
- CIt is a long-acting opioid that prevents withdrawal and craving
- DIt causes vomiting if other opioids are used
4.中等
服用甲硝唑的患者通常被建议避免:
- A日晒
- B乳制品
- C西柚汁
- D饮酒
5.中等
Which drug is used for torsades de pointes?
- AIntravenous adenosine (rapid push)
- BOral digoxin
- CIntravenous verapamil
- DIntravenous magnesium sulfate
6.中等
按固定间隔给药,大约需要多长时间达到稳态?
- A10 个半衰期
- B只取决于剂量大小
- C1 个半衰期
- D4 到 5 个半衰期
7.困难
A patient on methadone is also prescribed diazepam for anxiety. What is the main safety concern?
- ASevere hypertension from the combination
- BDiazepam blocks the effect of methadone completely
- CAdditive sedation and respiratory depression
- DMethadone causes diazepam to be excreted very quickly
8.困难
An older patient who has taken omeprazole for many years has muscle cramps, tremor and an irregular heartbeat. Which lab finding is most likely linked to the drug?
- AHigh serum calcium
- BLow serum glucose
- CLow serum magnesium
- DHigh serum sodium
答案
- 1. B · Oestrogen receptor-positive breast cancer
- 2. B · Tumour necrosis factor-alpha (TNF-alpha)
- 3. C · It is a long-acting opioid that prevents withdrawal and craving
- 4. D · 饮酒
- 5. D · Intravenous magnesium sulfate
- 6. D · 4 到 5 个半衰期
- 7. C · Additive sedation and respiratory depression
- 8. C · Low serum magnesium
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