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الاسم: ____________________ التاريخ: ____________
1.سهلة
Finasteride is used in benign prostatic hyperplasia because it:
ARelaxes smooth muscle in the prostate within hours of the first dose
BIncreases testosterone production
CInhibits 5-alpha reductase and slowly shrinks the prostate
DKills bacteria in the prostate
2.سهلة
How does activated charcoal work in poisoning?
AIt binds (adsorbs) the poison in the gut so less is absorbed
BIt makes the patient vomit the poison before it is absorbed
CIt speeds up liver metabolism of the poison
DIt neutralises acids in the blood
3.سهلة
Montelukast, used in asthma, belongs to which drug class?
AAntimuscarinic bronchodilators
BShort-acting beta-2 agonists
CLeukotriene receptor antagonists
DInhaled corticosteroids
4.متوسطة
Which approach is usually recommended to prevent constipation in a patient on regular opioids?
AAn antidiarrhoeal drug at night to slow the gut
BNo laxative until the patient has not opened the bowels for a week
CBulk-forming fibre alone, with fluid intake restricted
DA stimulant laxative such as senna, often with a stool softener
5.متوسطة
After instilling eye drops, why should the patient press gently on the inner corner of the eye for a minute or two?
ATo spread the drop evenly over the eyelid
BTo reduce drainage into the nose and absorption into blood
CTo stop the eye from producing tears for about an hour
DTo make the pupil dilate faster
6.متوسطة
دواء يثبط إنزيم الكبد CYP3A4. ماذا قد يحدث لدواء ثانٍ يُستقلب أساسًا بواسطة CYP3A4؟
Aينخفض مستواه في البلازما فقد يتوقف عن العمل بالجرعة المعتادة
Bتطرحه الكليتان أسرع
Cيرتفع مستواه في البلازما فيزداد خطر الآثار الجانبية
Dلا شيء، لأن الإنزيمات لا تؤثر في الأدوية الأخرى
7.صعبة
A heparin infusion contains 25,000 units in 500 mL. The order is 1,000 units per hour. What rate should be set on the pump?
A10 mL/h
B20 mL/h
C50 mL/h
D25 mL/h
8.صعبة
A teenager took a large overdose of diphenhydramine. He is agitated, hot, flushed and confused, with dry skin, dilated pupils and a full bladder. What is this pattern?
AAnticholinergic toxidrome
BOpioid toxidrome
CSerotonin syndrome
DCholinergic toxidrome
مفتاح الإجابات
1. C · Inhibits 5-alpha reductase and slowly shrinks the prostate
2. A · It binds (adsorbs) the poison in the gut so less is absorbed
3. C · Leukotriene receptor antagonists
4. D · A stimulant laxative such as senna, often with a stool softener
5. B · To reduce drainage into the nose and absorption into blood
6. C · يرتفع مستواه في البلازما فيزداد خطر الآثار الجانبية
7. B · 20 mL/h
8. A · Anticholinergic toxidrome
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