1Practice problems
1.Human anatomyMedium
The circle of Willis at the base of the brain connects which two arterial supplies?
- AJugular and vertebral systems
- BLeft and right external carotid arteries
- CExternal carotid and subclavian arterial systems
- DInternal carotid and vertebrobasilar systems
2.Human anatomyHard
Injury to the common fibular (peroneal) nerve at the neck of the fibula typically causes:
- ALoss of sensation on the sole of the foot
- BFoot drop
- CWeak hip abduction
- DInability to flex the knee
3.Human physiologyMedium
Which protein forms the mesh that stabilises a blood clot?
- AFibrin
- BThrombin
- CAlbumin
- DCollagen
4.Human physiologyHard
A patient has taken high-dose prednisolone for a year. What is the state of the hypothalamic–pituitary–adrenal axis?
- AACTH is high and the adrenal cortex is enlarged
- BACTH is suppressed and the adrenal cortex has atrophied
- CACTH is normal and cortisol production is increased
- DThe adrenal medulla has stopped making adrenaline and noradrenaline
2Solutions
1.Human anatomy
Answer: D · Internal carotid and vertebrobasilar systems
Why this is the answer
The circle of Willis links the internal carotid arteries with the basilar artery (formed by the vertebral arteries), allowing some collateral flow.
D · Internal carotid and vertebrobasilar systems
2.Human anatomy
Answer: B · Foot drop
Why this is the answer
The common fibular nerve supplies the dorsiflexors and evertors. Damage at the fibular neck causes foot drop and a high-stepping gait. The sole is supplied by the tibial nerve.
3.Human physiology
Answer: A · Fibrin
Why this is the answer
Thrombin converts soluble fibrinogen into insoluble fibrin strands, which bind the platelet plug and trap red cells to form a stable clot.
4.Human physiology
Answer: B · ACTH is suppressed and the adrenal cortex has atrophied
Why this is the answer
Exogenous glucocorticoid suppresses CRH and ACTH, so the adrenal cortex atrophies. Stopping the drug suddenly can cause an adrenal crisis, so it is tapered.
B · ACTH is suppressed and the adrenal cortex has atrophied