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Nama: ____________________ Tanggal: ____________
1.Mudah
Which description fits insulin glargine?
AA rapid-acting insulin given with each meal
BAn oral tablet that makes the pancreas release insulin
CA long-acting basal insulin with no marked peak
DAn intermediate-acting cloudy insulin with a clear peak
2.Mudah
In the United States, what is a "boxed warning" (black box warning) on a drug label?
AA note that the drug is available without prescription
BThe strongest FDA warning about a serious or life-threatening risk
CA sign that the drug must be stored in a dark box
DA label showing that the drug is a controlled substance with abuse potential
3.Mudah
Why is HIV treated with a combination of antiretroviral drugs?
ATo make the treatment shorter, usually a few weeks
BBecause one drug alone causes no side effects
CTo suppress the virus and prevent drug resistance
DBecause each single drug cures only part of the infection
4.Sedang
Sumatriptan is contraindicated in which patient?
AA patient with iron deficiency anaemia
BA patient with mild asthma
CA patient with coronary artery disease
DA patient with a recent ankle sprain
5.Sedang
How should a patient store sublingual glyceryl trinitrate (nitroglycerin) tablets?
AIn the original dark glass bottle, away from heat, light and moisture
BIn the fridge in a damp, open container to keep them fresh and cool
CLoose in a shirt pocket close to the body for quick access
DIn a plastic weekly pill box with other tablets
6.Sedang
Mengapa pasien yang mengonsumsi klozapin memerlukan pemeriksaan darah lengkap secara teratur?
AKlozapin menaikkan jumlah trombosit secara berbahaya
BKlozapin dapat menyebabkan agranulositosis
CKlozapin mengubah golongan darah
DKlozapin sering menyebabkan anemia defisiensi besi
7.Sulit
Seorang pasien mengalami reaksi anafilaksis pada dosis pertama amoksisilin. Bagaimana reaksi ini diklasifikasikan dalam sistem A/B yang umum?
ATipe A, karena bergantung dosis dan dapat diprediksi dari farmakologi obat
BTipe B, karena tidak dapat diprediksi dan tidak berkaitan dengan kerja normal obat
CTipe A, karena dosisnya terlalu tinggi
DTipe B, karena hanya terjadi setelah penggunaan jangka panjang
8.Sulit
A patient on heparin for 7 days has a platelet count that has fallen by more than half, and a new leg vein thrombosis. What is the most likely cause and the key action?
AVitamin K deficiency; give vitamin K and continue heparin
BHeparin-induced thrombocytopenia; stop all heparin
CWarfarin skin necrosis; switch from heparin to warfarin at once
DNormal dilution of platelets; continue and recheck in a week
Kunci jawaban
1. C · A long-acting basal insulin with no marked peak
2. B · The strongest FDA warning about a serious or life-threatening risk
3. C · To suppress the virus and prevent drug resistance
4. C · A patient with coronary artery disease
5. A · In the original dark glass bottle, away from heat, light and moisture
6. B · Klozapin dapat menyebabkan agranulositosis
7. B · Tipe B, karena tidak dapat diprediksi dan tidak berkaitan dengan kerja normal obat
8. B · Heparin-induced thrombocytopenia; stop all heparin
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