Lembar kerja Farmakologi dengan jawaban

Celecoxib selectively inhibits which enzyme?

1. APhospholipase A2
2. BLipoxygenase
3. CCyclo-oxygenase-2 (COX-2)
4. DCyclo-oxygenase-1 (COX-1)

In Addison's disease, fludrocortisone is given to replace which hormone?

1. AAldosterone
2. BThyroxine
3. CAdrenaline
4. DCortisol

Oseltamivir is used to treat or prevent which infection?

1. AHIV
2. BInfluenza
3. CHerpes simplex
4. DTuberculosis

Apa efek samping terpenting dari sulfonilurea seperti glikazid?

1. AAsidosis laktat
2. BHipoglikemia
3. CBatuk kering
4. DHiperkalemia

Bethanechol may be used for non-obstructive urinary retention. How does it work?

1. AIt increases urine production in the kidney
2. BIt stimulates muscarinic receptors and contracts the bladder muscle
3. CIt shrinks the prostate gland
4. DIt blocks muscarinic receptors and relaxes the bladder wall muscle

Long-term use of metformin can cause a deficiency of which vitamin?

1. AVitamin K
2. BVitamin B12
3. CVitamin A
4. DVitamin D

Kodein diubah menjadi morfin oleh CYP2D6. Apa yang terjadi pada pasien yang merupakan ultra-rapid metaboliser CYP2D6?

1. AKodein diekskresikan tanpa berubah melalui urine
2. BLebih banyak morfin terbentuk, sehingga meningkatkan risiko toksisitas opioid
3. CKodein hampir tidak memberikan pereda nyeri karena sedikit morfin yang terbentuk
4. DKodein hanya diubah menjadi senyawa tidak aktif

A patient took a large paracetamol (acetaminophen) overdose 6 hours ago and feels well. Why is treatment still urgent?

1. AThe drug will cause kidney stones within a few hours
2. BParacetamol overdose only causes harm if symptoms start in the first hour
3. CThe patient is at risk of immediate respiratory arrest
4. DLiver damage appears 1–3 days later, and early treatment works best