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Nama: ____________________ Tanggal: ____________
1.Mudah
How does tamsulosin improve urine flow in benign prostatic hyperplasia?
AIt contracts the bladder muscle
BIt shrinks the prostate gland over months by blocking testosterone
CIt increases urine production in the kidney
DIt blocks alpha-1 receptors and relaxes prostate smooth muscle
2.Mudah
Where should an adrenaline (epinephrine) auto-injector be given?
AInto the outer thigh muscle
BUnder the tongue
CInto the abdomen under the skin
DInto a vein in the arm
3.Mudah
Finasteride is used in benign prostatic hyperplasia because it:
AKills bacteria in the prostate
BRelaxes smooth muscle in the prostate within hours of the first dose
CInhibits 5-alpha reductase and slowly shrinks the prostate
DIncreases testosterone production
4.Sedang
After a vaccination, why is a person asked to wait for a short time before leaving?
ATo watch for anaphylaxis, which usually starts within minutes
BTo check that the vaccine has already created protective antibodies
CTo measure the person's temperature for fever
DTo make sure the injection site does not bruise
5.Sedang
Seorang pasien mengalami gangguan ginjal berat. Suatu obat terutama diekskresikan tanpa berubah melalui urine. Apa penyesuaian yang lazim?
AMenurunkan dosis atau memperpanjang interval pemberian
BMemberikan obat secara oral alih-alih intravena
CTidak perlu perubahan, karena hati mengambil alih
DMenaikkan dosis untuk mengimbangi penyerapan yang buruk
6.Sedang
Efek samping statin yang serius tetapi jarang manakah yang harus segera dilaporkan pasien?
APembengkakan pergelangan kaki
BBatuk kering
CNyeri atau kelemahan otot yang tidak dapat dijelaskan
DRasa logam di mulut
7.Sulit
A 19-year-old woman is starting isotretinoin for severe acne. Which requirement is most important?
AReliable contraception and pregnancy tests, as it is highly teratogenic
BA high-vitamin A diet to boost the effect
CTaking the drug only at weekends
DWeekly hearing tests and monthly eye examinations during treatment
8.Sulit
A patient on heparin for 7 days has a platelet count that has fallen by more than half, and a new leg vein thrombosis. What is the most likely cause and the key action?
AWarfarin skin necrosis; switch from heparin to warfarin at once
BNormal dilution of platelets; continue and recheck in a week
CVitamin K deficiency; give vitamin K and continue heparin
DHeparin-induced thrombocytopenia; stop all heparin
Kunci jawaban
1. D · It blocks alpha-1 receptors and relaxes prostate smooth muscle
2. A · Into the outer thigh muscle
3. C · Inhibits 5-alpha reductase and slowly shrinks the prostate
4. A · To watch for anaphylaxis, which usually starts within minutes
5. A · Menurunkan dosis atau memperpanjang interval pemberian
6. C · Nyeri atau kelemahan otot yang tidak dapat dijelaskan
7. A · Reliable contraception and pregnancy tests, as it is highly teratogenic
8. D · Heparin-induced thrombocytopenia; stop all heparin
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