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Nama: ____________________ Tanggal: ____________
1.Mudah
Why is adrenaline (epinephrine) sometimes added to a local anaesthetic injection?
AIt constricts vessels, so the block lasts longer and less enters the blood
BIt speeds up the removal of the anaesthetic from the tissue into the blood
CIt makes the anaesthetic act on the brain as well
DIt prevents allergic reactions to the anaesthetic
2.Mudah
What is the normal serum potassium range in adults?
A3,5–5,0 mmol/L
B1,5–2,5 mmol/L
C6,0–7,5 mmol/L
D135–145 mmol/L
3.Mudah
Levodopa terutama digunakan untuk mengobati penyakit apa?
APenyakit Parkinson
BEpilepsi
CPenyakit Alzheimer
DSklerosis multipel
4.Sedang
A malnourished patient with alcohol dependence needs IV glucose. Which vitamin should be given before or with it?
AThiamine (vitamin B1)
BVitamin D
CVitamin C
DVitamin K (phytomenadione)
5.Sedang
Which drug is used for torsades de pointes?
AIntravenous magnesium sulfate
BIntravenous adenosine (rapid push)
COral digoxin
DIntravenous verapamil
6.Sedang
A patient with insulin-treated diabetes is found unconscious with very low blood glucose. There is no IV access. Which drug can a trained helper give?
AIntramuscular adrenaline
BGlucagon by injection or nasal spray
CRapid-acting insulin under the skin
DOral glucose gel poured into the mouth
7.Sulit
Why is clavulanic acid combined with amoxicillin (co-amoxiclav)?
AIt makes amoxicillin cross the blood–brain barrier more easily
BIt slows the kidney excretion of amoxicillin
CIt reduces the risk of penicillin allergy
DIt inhibits beta-lactamase enzymes that would destroy amoxicillin
8.Sulit
Sifat apa yang membuat obat lebih mungkin menembus sawar darah-otak?
AKelarutan lemak tinggi dan ukuran kecil
BKelarutan air tinggi dan ionisasi kuat
CBerat molekul besar dan ikatan protein kuat
DMuatan positif pada pH fisiologis
Kunci jawaban
1. A · It constricts vessels, so the block lasts longer and less enters the blood
2. A · 3,5–5,0 mmol/L
3. A · Penyakit Parkinson
4. A · Thiamine (vitamin B1)
5. A · Intravenous magnesium sulfate
6. B · Glucagon by injection or nasal spray
7. D · It inhibits beta-lactamase enzymes that would destroy amoxicillin
8. A · Kelarutan lemak tinggi dan ukuran kecil
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