Lembar kerja Farmakologi dengan jawaban

Manakah yang merupakan reaksi fase II (konjugasi) yang khas dalam metabolisme obat?

1. AGlukuronidasi
2. BHidrolisis
3. CReduksi
4. DOksidasi

Giving a patient immunoglobulin after exposure to an infection provides which type of immunity?

1. AInnate immunity
2. BActive immunity
3. CPassive immunity
4. DHerd immunity

Which long-term side effect of phenytoin makes good oral hygiene especially important?

1. ALoss of taste
2. BExcess saliva production
3. COvergrowth of the gums (gingival hyperplasia)
4. DBlue-grey discoloration of the teeth and gums

A patient takes theophylline for COPD. Which advice is most important?

1. AAvoid potassium-rich foods such as bananas
2. BDrink plenty of grapefruit juice each morning to improve absorption
3. CLimit coffee, tea and cola, because caffeine adds to the side effects
4. DTake extra doses when short of breath

Which assessment is most important before giving a dose of IV morphine?

1. ABowel sounds and urine colour
2. BRespiratory rate and level of sedation
3. CBlood glucose and temperature, checked before each dose
4. DPupil size and hearing

Bethanechol may be used for non-obstructive urinary retention. How does it work?

1. AIt blocks muscarinic receptors and relaxes the bladder wall muscle
2. BIt increases urine production in the kidney
3. CIt stimulates muscarinic receptors and contracts the bladder muscle
4. DIt shrinks the prostate gland

Why may omeprazole be avoided in a patient taking clopidogrel?

1. AIt inhibits CYP2C19, so less clopidogrel is converted to its active form
2. BIt increases clopidogrel absorption from the gut and causes bleeding
3. CIt binds clopidogrel in the stomach and makes it insoluble
4. DIt speeds up kidney excretion of clopidogrel

A breastfeeding mother needs a mild analgesic. Which drug is generally considered compatible with breastfeeding?

1. AParacetamol (acetaminophen)
2. BCodeine (as co-codamol)
3. CPethidine (meperidine)
4. DAspirin