Lembar kerja Farmakologi dengan jawaban

What is enzyme induction?

1. AA drug causes an allergic reaction to enzymes
2. BA drug is converted into an enzyme in the body
3. CA drug speeds up liver enzymes, so other drugs are broken down faster
4. DA drug blocks liver enzymes, so other drugs build up in the blood

Why is HIV treated with a combination of antiretroviral drugs?

1. ABecause one drug alone causes no side effects
2. BTo make the treatment shorter, usually a few weeks
3. CBecause each single drug cures only part of the infection
4. DTo suppress the virus and prevent drug resistance

Protein plasma mana yang mengikat sebagian besar obat bersifat asam, seperti warfarin?

1. AAlbumin
2. BInsulin
3. CHemoglobin
4. DFibrinogen

Why is testing for HLA-B*15:02 recommended before carbamazepine in people of some Asian ancestries?

1. AThis gene variant speeds up the kidney excretion of carbamazepine
2. BThis gene variant makes carbamazepine ineffective
3. CThis gene variant causes carbamazepine to raise blood glucose
4. DIt greatly raises the risk of Stevens–Johnson syndrome

100 mL of an antibiotic is to be given over 30 minutes using a giving set of 20 drops/mL. What is the drip rate?

1. AAbout 20 drops per minute
2. BAbout 33 drops per minute
3. CAbout 100 drops per minute
4. DAbout 67 drops per minute

Why is simvastatin traditionally taken in the evening?

1. AIt causes too much drowsiness to be taken in the morning
2. BIt is short-acting, and cholesterol synthesis peaks at night
3. CIt must be taken with the largest meal of the day
4. DIt is inactivated by sunlight during the day

Untuk obat dengan eliminasi orde pertama, menggandakan dosis (tanpa mengubah interval) akan:

1. AMenggandakan waktu paruh
2. BTidak mengubah kadar keadaan tunak tetapi menjadikan waktu untuk mencapainya separuhnya
3. CMemangkas setengah waktu untuk mencapai keadaan tunak
4. DMenggandakan kadar keadaan tunak tetapi tidak mengubah waktu untuk mencapainya

A patient with latent tuberculosis feels well and is not infectious. Why is treatment such as isoniazid still offered?

1. ATo prevent progression to active TB later
2. BTo cure an active lung infection
3. CTo produce a negative skin test quickly
4. DTo stop the patient spreading TB at the moment