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Nama: ____________________ Tanggal: ____________
1.Mudah
Benzodiazepin seperti diazepam bekerja dengan meningkatkan efek neurotransmiter apa?
ASerotonin
BGlutamat
CGABA
DNoradrenalin
2.Mudah
Fibrates such as fenofibrate mainly lower which blood lipid?
ATriglycerides
BHDL cholesterol
CLipoprotein(a) only
DBile acids
3.Mudah
What is drug synergism?
ATwo drugs together produce exactly the sum of their separate effects
BA drug loses its effect after repeated doses
COne drug cancels out the effect of another drug
DTwo drugs together have a greater effect than the sum of each alone
4.Sedang
Mengapa doksisiklin tidak boleh diminum bersamaan dengan susu atau antasida?
AKombinasinya menyebabkan konstipasi berat
BSusu mempercepat penguraiannya di hati melalui induksi enzim
CKalsium dan ion logam lain mengikatnya dan mengurangi penyerapan
DAntasida mengubahnya menjadi senyawa toksik
5.Sedang
Why is a spacer recommended with a metered-dose inhaler?
AMore drug reaches the lungs and less stays in the mouth
BIt turns the inhaler into a nebuliser
CIt removes the need to shake the inhaler
DIt doubles the dose of drug released by each puff of the inhaler
6.Sedang
A patient refuses a prescribed oral medicine. What should the nurse do?
ARecord the medicine as given, so that the chart stays complete for the next shift
BExplore the reason, respect the decision, document and inform the prescriber
CLeave the tablet on the bedside table for later
DHide the tablet in the patient's food
7.Sulit
Why do infants absorb more of a topical corticosteroid than adults?
ATheir skin contains no blood vessels
BTheir liver changes the cream into a much stronger form
CThey have more skin area per kilogram and thinner skin
DInfants do not absorb topical drugs at all
8.Sulit
A patient with asthma starts timolol eye drops for glaucoma and soon becomes wheezy. What is the most likely explanation?
AThe eye drops contain an allergen that causes hay fever and asthma
BTimolol is absorbed and blocks beta-2 receptors in the airways
CThe wheeze is unrelated to the eye drops
DTimolol activates histamine receptors in the lungs
Kunci jawaban
1. C · GABA
2. A · Triglycerides
3. D · Two drugs together have a greater effect than the sum of each alone
4. C · Kalsium dan ion logam lain mengikatnya dan mengurangi penyerapan
5. A · More drug reaches the lungs and less stays in the mouth
6. B · Explore the reason, respect the decision, document and inform the prescriber
7. C · They have more skin area per kilogram and thinner skin
8. B · Timolol is absorbed and blocks beta-2 receptors in the airways
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