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Nama: ____________________ Tanggal: ____________
1.Mudah
Organ mana yang terutama memetabolisme sebagian besar obat?
ALimpa
BHati
CGinjal
DParu-paru
2.Mudah
Apa tujuan salut enterik (enteric coating) pada tablet?
AMembuat tablet keluar dari tubuh tanpa berubah melalui tinja
BMembuat tablet terasa manis
CMencegah tablet larut sampai mencapai usus
DMembuat tablet larut di mulut
3.Mudah
Statin seperti atorvastatin menurunkan kolesterol dengan menghambat enzim apa?
ASiklooksigenase
BEnzim pengubah angiotensin
CHMG-CoA reduktase
DLipoprotein lipase
4.Sedang
Efek samping umum apa yang khas untuk penghambat ACE?
ABatuk kering
BBengkak pergelangan kaki karena vasodilatasi
CBradikardia
DHipoglikemia
5.Sedang
A patient takes cholestyramine. How should other oral medicines be timed?
ATake them 1 hour before or several hours after cholestyramine
BMix them into the cholestyramine drink so they are taken together
CTake them all at the same time as cholestyramine
DTiming does not matter, as cholestyramine is not absorbed
6.Sedang
Why should a patient rinse the mouth after using an inhaled corticosteroid?
ATo stop the drug being absorbed too quickly into the blood
BTo make the drug work faster in the lungs
CTo reduce the risk of oral thrush (candidiasis) and hoarseness
DTo prevent a fall in blood glucose
7.Sulit
A patient on valproate becomes lethargic, starts vomiting and develops jaundice. Which adverse effect should be suspected first?
AKidney stones
BNormal start-up side effects
CHypothyroidism
DLiver toxicity
8.Sulit
Beta-lactam antibiotics show time-dependent killing. What does this mean for administration?
AA single very large daily dose works best
BDoses should be given only when the patient has a fever
CDoses should be given on time at evenly spaced intervals
DDoses can be given at any time as long as the daily total is right
Kunci jawaban
1. B · Hati
2. C · Mencegah tablet larut sampai mencapai usus
3. C · HMG-CoA reduktase
4. A · Batuk kering
5. A · Take them 1 hour before or several hours after cholestyramine
6. C · To reduce the risk of oral thrush (candidiasis) and hoarseness
7. D · Liver toxicity
8. C · Doses should be given on time at evenly spaced intervals
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