Lembar kerja Farmakologi dengan jawaban

Tamoxifen is used mainly to treat:

1. AOsteoarthritis
2. BOestrogen receptor-positive breast cancer
3. CType 2 diabetes
4. DProstate enlargement and prostate cancer in older men

Methylphenidate, used in ADHD, belongs to which class?

1. AOpioid analgesics
2. BAntipsychotics (dopamine blockers)
3. CBenzodiazepines
4. DCentral nervous system stimulants

In the United States, what is a "boxed warning" (black box warning) on a drug label?

1. AA sign that the drug must be stored in a dark box
2. BThe strongest FDA warning about a serious or life-threatening risk
3. CA note that the drug is available without prescription
4. DA label showing that the drug is a controlled substance with abuse potential

Warfarin bekerja dengan:

1. AMenghambat agregasi trombosit melalui penghambatan ireversibel COX-1
2. BMenghambat sintesis faktor pembekuan yang bergantung vitamin K
3. CMenghambat trombin secara langsung
4. DMengaktifkan antitrombin

Which early signs suggest systemic toxicity from a local anaesthetic?

1. ANumbness around the mouth, metallic taste and tinnitus
2. BPinpoint pupils and slow, shallow breathing
3. CHeavy sweating, salivation and diarrhoea
4. DItchy rash and swelling only at the injection site

Apa yang membuat overdosis antidepresan trisiklik seperti amitriptilin sangat berbahaya?

1. ABatu ginjal
2. BGagal hati berat dalam beberapa jam
3. CAritmia jantung dan kejang
4. DGlukosa darah tinggi mendadak

How does aripiprazole differ from most other antipsychotics?

1. AIt has no effect on dopamine and acts only on histamine
2. BIt works by blocking the reuptake of serotonin only
3. CIt is a full dopamine agonist that increases dopamine activity
4. DIt is a partial agonist at dopamine D2 receptors

A patient with an epidural infusion of local anaesthetic becomes hypotensive. What is the most likely mechanism?

1. ABlockade of sympathetic nerves causes vasodilation
2. BThe epidural catheter has caused heavy bleeding
3. CThe drug increases urine output and causes dehydration
4. DThe local anaesthetic causes a severe allergic reaction