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Nama: ____________________ Tanggal: ____________
1.Mudah
Apa yang dimaksud dengan nama generik suatu obat?
ANama yang dipilih perusahaan untuk pemasaran
BNama apotek yang membuatnya
CNama nonpaten (non-proprietary) zat aktifnya
DRumus kimia yang tercetak di kemasan
2.Mudah
Drugs whose names end in "-sartan", such as losartan, belong to which class?
AACE inhibitors, which block the converting enzyme
BLoop diuretics
CAlpha-1 blockers
DAngiotensin II receptor blockers
3.Mudah
Finasteride is used in benign prostatic hyperplasia because it:
ARelaxes smooth muscle in the prostate within hours of the first dose
BIncreases testosterone production
CInhibits 5-alpha reductase and slowly shrinks the prostate
DKills bacteria in the prostate
4.Sedang
Apa efek samping terpenting dari sulfonilurea seperti glikazid?
AAsidosis laktat
BHipoglikemia
CBatuk kering
DHiperkalemia
5.Sedang
Which advice helps reduce the most common side effect of varenicline?
ATake it with alcohol to reduce nausea
BTake it after food with a full glass of water
CTake double doses in the first week
DTake it on an empty stomach at bedtime with a little milk
6.Sedang
A man taking tamsulosin is planning cataract surgery. What should the nurse advise?
ATell the eye surgeon, as it can cause floppy iris syndrome
BStop the drug for one day and no further action is needed
CThe drug has no link with eye surgery
DTake a double dose on the day of surgery
7.Sulit
Pada overdosis aspirin, urine dapat dibuat basa dengan natrium bikarbonat. Mengapa hal ini meningkatkan ekskresi salisilat?
ABikarbonat mempercepat metabolisme salisilat di hati menjadi bentuk tidak aktif
BBikarbonat mengikat salisilat dan membuatnya tidak aktif
CLebih banyak salisilat terionisasi di tubulus, sehingga lebih sedikit yang direabsorpsi
DUrine basa meningkatkan filtrasi glomerulus
8.Sulit
A patient develops a dry cough on an ACE inhibitor and is switched to losartan. Why is losartan less likely to cause cough?
AIt is excreted faster by the kidney
BIt does not block the breakdown of bradykinin
CIt blocks histamine receptors in the airways
DIt also acts as a bronchodilator
Kunci jawaban
1. C · Nama nonpaten (non-proprietary) zat aktifnya
2. D · Angiotensin II receptor blockers
3. C · Inhibits 5-alpha reductase and slowly shrinks the prostate
4. B · Hipoglikemia
5. B · Take it after food with a full glass of water
6. A · Tell the eye surgeon, as it can cause floppy iris syndrome
7. C · Lebih banyak salisilat terionisasi di tubulus, sehingga lebih sedikit yang direabsorpsi
8. B · It does not block the breakdown of bradykinin
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