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Nama: ____________________ Tanggal: ____________
1.Mudah
Obat oral mana yang umumnya menjadi obat lini pertama untuk diabetes tipe 2?
AInsulin glargin
BPrednisolon
CLevotiroksin
DMetformin
2.Mudah
Obat yang namanya berakhiran "-olol", seperti atenolol, termasuk golongan apa?
APenyekat beta
BStatin
CPenyekat kanal kalsium
DPenghambat ACE
3.Mudah
How does allopurinol prevent gout?
AIt blocks prostaglandins in the inflamed joint
BIt inhibits xanthine oxidase, so less uric acid is made
CIt increases the kidney excretion of calcium
DIt dissolves crystals already in the joint within hours
4.Sedang
Mengapa doksisiklin tidak boleh diminum bersamaan dengan susu atau antasida?
AKalsium dan ion logam lain mengikatnya dan mengurangi penyerapan
BSusu mempercepat penguraiannya di hati melalui induksi enzim
CAntasida mengubahnya menjadi senyawa toksik
DKombinasinya menyebabkan konstipasi berat
5.Sedang
A patient receives lactulose for hepatic encephalopathy. Which finding shows that it is working?
ANo bowel movement for three days, with less confusion than before
BBetter alertness and orientation, with two to three soft stools a day
CHigher blood ammonia with improved appetite
DTen watery stools a day and a low serum potassium
6.Sedang
A patient given haloperidol develops a sudden painful twisting of the neck and the eyes roll upward. Which drug is usually given?
ADantrolene by mouth to relax the twisted neck muscles
BA second dose of haloperidol
CAn anticholinergic such as benzatropine (benztropine)
DNaloxone
7.Sulit
A patient taking co-trimoxazole develops fever, a spreading blistering rash and painful mouth sores. What is the most likely diagnosis?
AStevens–Johnson syndrome; stop the drug and get urgent medical care
BSunburn caused by the drug; advise sunscreen only
CA mild rash that will settle; continue the drug and give moisturiser
DOral thrush; start an antifungal and continue the antibiotic
8.Sulit
A patient taking metoprolol is also started on verapamil. Which adverse effect is most likely?
ASevere bradycardia and heart block
BHypoglycaemia and weight gain
CRebound tachycardia and hypertension
DHyperkalaemia and muscle weakness
Kunci jawaban
1. D · Metformin
2. A · Penyekat beta
3. B · It inhibits xanthine oxidase, so less uric acid is made
4. A · Kalsium dan ion logam lain mengikatnya dan mengurangi penyerapan
5. B · Better alertness and orientation, with two to three soft stools a day
6. C · An anticholinergic such as benzatropine (benztropine)
7. A · Stevens–Johnson syndrome; stop the drug and get urgent medical care
8. A · Severe bradycardia and heart block
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