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Nama: ____________________ Tanggal: ____________
1.Mudah
What is the purpose of the Z-track technique for intramuscular injections?
ATo avoid the need to clean the skin
BTo make the injection faster
CTo allow a larger volume to be given than with a standard injection
DTo stop the drug leaking back into the subcutaneous tissue
2.Mudah
Apa arti "waktu paruh" suatu obat?
AWaktu agar konsentrasi plasma turun menjadi setengahnya
BWaktu agar setengah dosis diserap dari usus
CWaktu sampai obat mulai bekerja
DSetengah dari lama obat berada di tubuh
3.Mudah
Permethrin is used to treat:
AScabies and head lice
BPsoriasis
CAcne
DFungal nail infections
4.Sedang
Which approach is usually recommended to prevent constipation in a patient on regular opioids?
AA stimulant laxative such as senna, often with a stool softener
BNo laxative until the patient has not opened the bowels for a week
CAn antidiarrhoeal drug at night to slow the gut
DBulk-forming fibre alone, with fluid intake restricted
5.Sedang
A patient takes cholestyramine. How should other oral medicines be timed?
ATake them 1 hour before or several hours after cholestyramine
BMix them into the cholestyramine drink so they are taken together
CTake them all at the same time as cholestyramine
DTiming does not matter, as cholestyramine is not absorbed
6.Sedang
After naloxone reverses an opioid overdose, why must the patient be watched closely?
ANaloxone makes the opioid stay longer in the body
BNaloxone often causes severe low blood glucose a few hours after the dose
CNaloxone itself causes respiratory depression at high doses
DNaloxone may wear off before the opioid does, so breathing can slow again
7.Sulit
A patient who used cocaine has chest pain, agitation, a high temperature, sweating, tachycardia and dilated pupils. Which drug class is commonly first-line for the agitation and sympathetic overactivity?
AOpioid antagonists
BAntihistamines
CBenzodiazepines
DAnticholinergic drugs
8.Sulit
A patient who used heroin a few hours ago is given a first dose of buprenorphine and quickly develops severe withdrawal. Why?
ABuprenorphine is a high-affinity partial agonist that displaces heroin
BBuprenorphine has no effect at opioid receptors
CBuprenorphine is a pure antagonist like naloxone with no agonist effect
DBuprenorphine causes an allergic reaction in heroin users
Kunci jawaban
1. D · To stop the drug leaking back into the subcutaneous tissue
2. A · Waktu agar konsentrasi plasma turun menjadi setengahnya
3. A · Scabies and head lice
4. A · A stimulant laxative such as senna, often with a stool softener
5. A · Take them 1 hour before or several hours after cholestyramine
6. D · Naloxone may wear off before the opioid does, so breathing can slow again
7. C · Benzodiazepines
8. A · Buprenorphine is a high-affinity partial agonist that displaces heroin
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