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Nama: ____________________ Tanggal: ____________
1.Mudah
Why is magnesium sulfate given to a woman with severe pre-eclampsia?
ATo raise her blood pressure
BTo prevent eclamptic seizures
CTo start labour contractions
DTo treat a urinary infection
2.Mudah
Which drug is the antidote for magnesium sulfate toxicity?
AProtamine sulfate
BNaloxone
CCalcium gluconate
DPotassium chloride
3.Mudah
Manakah yang merupakan reaksi fase II (konjugasi) yang khas dalam metabolisme obat?
AHidrolisis
BGlukuronidasi
COksidasi
DReduksi
4.Sedang
Which assessments are most important during a magnesium sulfate infusion?
ADeep tendon reflexes, respiratory rate and urine output
BBowel sounds and appetite
CBlood glucose, pupil size and pupil reaction to light
DTemperature and skin colour only
5.Sedang
A patient uses a salbutamol (albuterol) inhaler and a corticosteroid inhaler at the same time of day. Which order is usually taught?
AThe order does not matter and no waiting is needed
BUse the salbutamol first, wait a few minutes, then use the steroid
CUse both in the same breath to save time
DUse the steroid first, then the salbutamol right after without any gap
6.Sedang
Apa yang membuat overdosis antidepresan trisiklik seperti amitriptilin sangat berbahaya?
AGlukosa darah tinggi mendadak
BGagal hati berat dalam beberapa jam
CBatu ginjal
DAritmia jantung dan kejang
7.Sulit
Antagonis nonkompetitif (ireversibel) mengubah kurva dosis-respons dengan:
AMembuat kurva lebih curam tanpa perubahan lain
BMenurunkan respons maksimum
CMenggeser kurva ke kiri
DMenggeser kurva ke kanan dengan maksimum yang sama
8.Sulit
A man taking doxazosin for hypertension starts sildenafil for erectile dysfunction. What is the main risk?
AHyperkalaemia
BSevere hypertension and a pounding headache
CSymptomatic low blood pressure and fainting
DBronchospasm
Kunci jawaban
1. B · To prevent eclamptic seizures
2. C · Calcium gluconate
3. B · Glukuronidasi
4. A · Deep tendon reflexes, respiratory rate and urine output
5. B · Use the salbutamol first, wait a few minutes, then use the steroid
6. D · Aritmia jantung dan kejang
7. B · Menurunkan respons maksimum
8. C · Symptomatic low blood pressure and fainting
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