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Nama: ____________________ Tanggal: ____________
1.Mudah
Which harmless effect of rifampicin should patients be warned about?
AWhite spots on the teeth
BBlue colouring of the fingernails and lips
COrange-red colouring of urine, sweat and tears
DGreen colouring of the stools
2.Mudah
Which drug is an antidote for methanol or ethylene glycol (antifreeze) poisoning?
AAtropine
BNaloxone
CFlumazenil
DFomepizole
3.Mudah
Which adverse effect is most common with colchicine?
ADrowsiness and slow breathing
BConstipation and dry mouth
CWeight gain and swelling
DDiarrhoea, nausea and vomiting
4.Sedang
How are most medication doses for children calculated?
ABy body weight in kilograms, or sometimes body surface area
BBy the child's height alone
CBy the child's age in years only
DBy giving half of the adult dose to all children under 12
5.Sedang
Which drug is used for torsades de pointes?
AIntravenous adenosine (rapid push)
BIntravenous magnesium sulfate
COral digoxin
DIntravenous verapamil
6.Sedang
Why is a progestogen added to oestrogen in hormone replacement therapy for a woman who still has her uterus?
ATo lower the risk of blood clots to zero
BTo reduce hot flushes much more than oestrogen alone can
CTo protect against endometrial hyperplasia and cancer
DTo prevent breast cancer completely
7.Sulit
A patient on lisinopril for hypertension starts taking ibuprofen every day for knee pain. What is the main concern?
AA higher risk of a dry cough than with lisinopril alone
BWeaker blood pressure control, kidney injury and high potassium
CA large fall in blood pressure, with fainting and falls on standing up
DFaster liver metabolism of lisinopril, so it stops working
8.Sulit
A patient taking co-trimoxazole develops fever, a spreading blistering rash and painful mouth sores. What is the most likely diagnosis?
ASunburn caused by the drug; advise sunscreen only
BStevens–Johnson syndrome; stop the drug and get urgent medical care
CA mild rash that will settle; continue the drug and give moisturiser
DOral thrush; start an antifungal and continue the antibiotic
Kunci jawaban
1. C · Orange-red colouring of urine, sweat and tears
2. D · Fomepizole
3. D · Diarrhoea, nausea and vomiting
4. A · By body weight in kilograms, or sometimes body surface area
5. B · Intravenous magnesium sulfate
6. C · To protect against endometrial hyperplasia and cancer
7. B · Weaker blood pressure control, kidney injury and high potassium
8. B · Stevens–Johnson syndrome; stop the drug and get urgent medical care
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