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Nama: ____________________ Tanggal: ____________
1.Mudah
Apa peran utama kortikosteroid inhalasi pada asma?
AMengencerkan lendir agar dapat dibatukkan
BMengurangi peradangan saluran napas dan mencegah serangan
CMembunuh bakteri di saluran napas
DMeredakan bronkospasme mendadak dalam beberapa menit
2.Mudah
Alendronate, used for osteoporosis, belongs to which class?
ABisphosphonates
BCorticosteroids
CThyroid hormones
DCalcium channel blockers
3.Mudah
Which intramuscular site is recommended for infants?
AVastus lateralis (outer thigh)
BVentral forearm
CDeltoid
DDorsogluteal (upper outer buttock)
4.Sedang
A patient with difficulty swallowing is prescribed several tablets. Which one should not be crushed?
AA plain paracetamol tablet
BA plain aspirin dispersible tablet
CA modified-release (extended-release) tablet
DA tablet that the pharmacist says may be crushed
5.Sedang
Why is a spacer recommended with a metered-dose inhaler?
AIt removes the need to shake the inhaler
BIt turns the inhaler into a nebuliser
CMore drug reaches the lungs and less stays in the mouth
DIt doubles the dose of drug released by each puff of the inhaler
6.Sedang
Which patient should usually not receive a live vaccine?
AA patient with mild seasonal allergies
BA healthy 1-year-old child
CA patient receiving chemotherapy for leukaemia
DA healthy adult nurse who works on a children's ward
7.Sulit
Suatu obat dengan waktu paruh pendek diberikan dengan interval dosis yang jauh lebih panjang daripada waktu paruhnya. Apa hasilnya pada keadaan tunak?
AFluktuasi besar antara kadar puncak dan kadar lembah
BKeadaan tunak tidak pernah tercapai
CAkumulasi bertahap hingga kadar toksik
DKadar sangat stabil hampir tanpa fluktuasi
8.Sulit
A patient taking sertraline starts St John's wort for low mood. What is the main concern?
ASevere low blood pressure from blocked alpha receptors
BSerotonin syndrome from combined serotonergic effects
CA hypertensive crisis from tyramine
DBleeding from vitamin K deficiency
Kunci jawaban
1. B · Mengurangi peradangan saluran napas dan mencegah serangan
2. A · Bisphosphonates
3. A · Vastus lateralis (outer thigh)
4. C · A modified-release (extended-release) tablet
5. C · More drug reaches the lungs and less stays in the mouth
6. C · A patient receiving chemotherapy for leukaemia
7. A · Fluktuasi besar antara kadar puncak dan kadar lembah
8. B · Serotonin syndrome from combined serotonergic effects
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