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Nama: ____________________ Tanggal: ____________
1.Mudah
Obat yang namanya berakhiran "-olol", seperti atenolol, termasuk golongan apa?
APenyekat kanal kalsium
BStatin
CPenghambat ACE
DPenyekat beta
2.Mudah
Benzodiazepin seperti diazepam bekerja dengan meningkatkan efek neurotransmiter apa?
ANoradrenalin
BSerotonin
CGABA
DGlutamat
3.Mudah
Which intramuscular site is recommended for infants?
AVastus lateralis (outer thigh)
BVentral forearm
CDeltoid
DDorsogluteal (upper outer buttock)
4.Sedang
Bagaimana neostigmin meningkatkan kekuatan otot pada miastenia gravis?
ANeostigmin langsung merangsang reseptor muskarinik di otot
BNeostigmin memblokir autoantibodi terhadap reseptor
CNeostigmin menghambat asetilkolinesterase sehingga lebih banyak asetilkolin mencapai reseptor
DNeostigmin meningkatkan jumlah reseptor asetilkolin di sambungan neuromuskular
5.Sedang
Which adverse effect is a well-known risk of zidovudine?
AGum overgrowth
BRed–green colour blindness
COrange-red colouring of the urine and tears
DBone marrow suppression, especially anaemia
6.Sedang
Why should NSAIDs be used with caution in some people with asthma?
AThey increase the clearance of salbutamol
BThey block the anti-inflammatory effect of inhaled corticosteroids
CThey can trigger bronchospasm in aspirin-sensitive asthma
DThey cause mucus plugs by drying the airways
7.Sulit
A patient on disulfiram becomes flushed, nauseated and has palpitations after using a mouthwash. What is the most likely cause?
AAn allergy to mint flavouring in the mouthwash
BDisulfiram toxicity from taking too many tablets by mistake
CAlcohol in the mouthwash caused a disulfiram–alcohol reaction
DLow blood glucose from skipping breakfast
8.Sulit
A pregnant woman develops a deep vein thrombosis. Which anticoagulant is usually preferred?
AWarfarin
BLow-molecular-weight heparin, such as enoxaparin
CRivaroxaban, a direct oral factor Xa inhibitor
DAspirin alone
Kunci jawaban
1. D · Penyekat beta
2. C · GABA
3. A · Vastus lateralis (outer thigh)
4. C · Neostigmin menghambat asetilkolinesterase sehingga lebih banyak asetilkolin mencapai reseptor
5. D · Bone marrow suppression, especially anaemia
6. C · They can trigger bronchospasm in aspirin-sensitive asthma
7. C · Alcohol in the mouthwash caused a disulfiram–alcohol reaction
8. B · Low-molecular-weight heparin, such as enoxaparin
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