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Nama: ____________________ Tanggal: ____________
1.Mudah
Which of these is a second-generation (atypical) antipsychotic?
AHaloperidol
BChlorpromazine
CFluphenazine
DOlanzapine
2.Mudah
Which of these is an extrapyramidal side effect of antipsychotics?
ADry mouth
BAkathisia (a feeling of inner restlessness)
CAgranulocytosis (a very low neutrophil count)
DWeight gain
3.Mudah
Apa yang digambarkan oleh "potensi" suatu obat?
AJumlah obat yang diperlukan untuk menghasilkan efek tertentu
BBerapa lama obat bertahan di dalam tubuh
CEfek terbesar yang dapat dihasilkan obat
DSeberapa aman obat dibandingkan obat lain dalam kelasnya
4.Sedang
Why should NSAIDs be used with caution in some people with asthma?
AThey increase the clearance of salbutamol
BThey cause mucus plugs by drying the airways
CThey block the anti-inflammatory effect of inhaled corticosteroids
DThey can trigger bronchospasm in aspirin-sensitive asthma
5.Sedang
A patient with diabetes is sweaty and shaky. Blood glucose is 3,0 mmol/L (54 mg/dL). The patient is awake and can swallow. What should the nurse do first?
AGive a large meal high in fat and protein to keep glucose up for longer
BGive the next scheduled dose of insulin
CGive 15–20 g of fast-acting carbohydrate, such as juice
DGive intramuscular glucagon at once
6.Sedang
Bagaimana metformin terutama menurunkan glukosa darah?
AMetformin menggantikan insulin yang kurang
BMetformin merangsang pelepasan insulin dari pankreas
CMetformin mengurangi produksi glukosa oleh hati
DMetformin memblokir penyerapan glukosa di ginjal
7.Sulit
Why is gentamicin often given once daily instead of in several small doses?
AIt has a very long half-life of several days
BIts killing depends on high peak levels, with a post-antibiotic effect
CIts killing depends only on the time the level stays above the MIC
DIt is absorbed slowly from the muscle over 24 hours
8.Sulit
Apa mekanisme kerja utama penghambat pompa proton seperti omeprazol?
AMelapisi tukak untuk melindunginya
BPenyekatan kompetitif reseptor histamin H2 di sel parietal
CPenghambatan ireversibel H⁺/K⁺-ATPase di sel parietal
DMenetralkan asam di lambung
Kunci jawaban
1. D · Olanzapine
2. B · Akathisia (a feeling of inner restlessness)
3. A · Jumlah obat yang diperlukan untuk menghasilkan efek tertentu
4. D · They can trigger bronchospasm in aspirin-sensitive asthma
5. C · Give 15–20 g of fast-acting carbohydrate, such as juice
6. C · Metformin mengurangi produksi glukosa oleh hati
7. B · Its killing depends on high peak levels, with a post-antibiotic effect
8. C · Penghambatan ireversibel H⁺/K⁺-ATPase di sel parietal
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