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Nama: ____________________ Tanggal: ____________
1.Mudah
Why is magnesium sulfate given to a woman with severe pre-eclampsia?
ATo prevent eclamptic seizures
BTo start labour contractions
CTo raise her blood pressure
DTo treat a urinary infection
2.Mudah
What is drug synergism?
ATwo drugs together produce exactly the sum of their separate effects
BOne drug cancels out the effect of another drug
CA drug loses its effect after repeated doses
DTwo drugs together have a greater effect than the sum of each alone
3.Mudah
How long does it usually take for an SSRI to improve mood noticeably?
AAbout six months
BA few hours
COne or two days
DSeveral weeks
4.Sedang
Benzathine benzylpenicillin (penicillin G benzathine) is ordered. Which route is correct?
ASubcutaneous in the abdomen
BDeep intramuscular only
CIntravenous push
DIntravenous infusion over 30 minutes
5.Sedang
A parent will give a liquid medicine to a child at home. Which advice is safest?
AUse the oral syringe or measuring cup supplied with it
BMix the dose into a full bottle of milk
CEstimate the dose by pouring the liquid into a small cup
DUse any kitchen teaspoon
6.Sedang
A patient receives lactulose for hepatic encephalopathy. Which finding shows that it is working?
ATen watery stools a day and a low serum potassium
BNo bowel movement for three days, with less confusion than before
CBetter alertness and orientation, with two to three soft stools a day
DHigher blood ammonia with improved appetite
7.Sulit
Pada overdosis aspirin, urine dapat dibuat basa dengan natrium bikarbonat. Mengapa hal ini meningkatkan ekskresi salisilat?
AUrine basa meningkatkan filtrasi glomerulus
BBikarbonat mengikat salisilat dan membuatnya tidak aktif
CLebih banyak salisilat terionisasi di tubulus, sehingga lebih sedikit yang direabsorpsi
DBikarbonat mempercepat metabolisme salisilat di hati menjadi bentuk tidak aktif
8.Sulit
Suatu obat memiliki volume distribusi 40 L dan bioavailabilitas lengkap. Dosis muatan (loading dose) berapa yang menghasilkan konsentrasi plasma target 2 mg/L?
A20 mg
B160 mg
C80 mg
D42 mg
Kunci jawaban
1. A · To prevent eclamptic seizures
2. D · Two drugs together have a greater effect than the sum of each alone
3. D · Several weeks
4. B · Deep intramuscular only
5. A · Use the oral syringe or measuring cup supplied with it
6. C · Better alertness and orientation, with two to three soft stools a day
7. C · Lebih banyak salisilat terionisasi di tubulus, sehingga lebih sedikit yang direabsorpsi
8. C · 80 mg
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