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Nama: ____________________ Tanggal: ____________
1.Mudah
In Addison's disease, fludrocortisone is given to replace which hormone?
AAldosterone
BThyroxine
CAdrenaline
DCortisol
2.Mudah
Donepezil, used in Alzheimer's disease, belongs to which class?
ADopamine agonists
BBenzodiazepines
CAcetylcholinesterase inhibitors
DSelective serotonin reuptake inhibitors
3.Mudah
Which long-term side effect of phenytoin makes good oral hygiene especially important?
ALoss of taste
BBlue-grey discoloration of the teeth and gums
COvergrowth of the gums (gingival hyperplasia)
DExcess saliva production
4.Sedang
Which blood test is commonly used to monitor a continuous infusion of unfractionated heparin?
ASerum potassium
BActivated partial thromboplastin time (aPTT)
CHaemoglobin A1c
DINR (international normalised ratio, prothrombin time)
5.Sedang
Agonis parsial diberikan bersama agonis penuh dosis tinggi. Apa yang terjadi pada responsnya?
ARespons berlipat dua, karena kedua obat mengaktifkan reseptor
BRespons turun, karena agonis parsial bersaing memperebutkan reseptor
CRespons tetap persis sama seperti pada dosis tinggi agonis penuh saja
DRespons naik melebihi maksimum agonis penuh
6.Sedang
Why is a spacer recommended with a metered-dose inhaler?
AIt removes the need to shake the inhaler
BMore drug reaches the lungs and less stays in the mouth
CIt turns the inhaler into a nebuliser
DIt doubles the dose of drug released by each puff of the inhaler
7.Sulit
Mengapa penyekat beta dapat menutupi tanda peringatan hipoglikemia pada penyandang diabetes?
AObat ini meredam gejala adrenergik seperti gemetar dan berdebar
BObat ini menaikkan gula darah sehingga hipoglikemia sama sekali tidak dapat terjadi
CObat ini menyebabkan demam yang menyembunyikan keringat
DObat ini menghentikan pelepasan insulin sepenuhnya
8.Sulit
A patient taking furosemide has a serum potassium of 2,9 mmol/L (mEq/L). Which ECG change is typical of this level?
AA short QT interval with high R waves
BFlattened T waves and prominent U waves
CWidened QRS with a sine-wave pattern
DTall, peaked T waves
Kunci jawaban
1. A · Aldosterone
2. C · Acetylcholinesterase inhibitors
3. C · Overgrowth of the gums (gingival hyperplasia)
4. B · Activated partial thromboplastin time (aPTT)
5. B · Respons turun, karena agonis parsial bersaing memperebutkan reseptor
6. B · More drug reaches the lungs and less stays in the mouth
7. A · Obat ini meredam gejala adrenergik seperti gemetar dan berdebar
8. B · Flattened T waves and prominent U waves
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