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Nama: ____________________ Tanggal: ____________
1.Mudah
What is a prodrug?
AA drug that is inactive until the body converts it into its active form
BA drug that has passed all clinical trials
CA drug that prevents or reverses the effect of another drug in the body
DA drug that is given before surgery
2.Mudah
What does "polypharmacy" mean?
AUsing a drug at a very high dose
BTaking one drug in several different forms
CThe use of many medicines at the same time, often five or more
DA pharmacy that stocks many different brands of the same drug
3.Mudah
Why is methadone used to treat opioid use disorder?
AIt is a pure opioid antagonist that blocks all opioid effects
BIt is a long-acting opioid that prevents withdrawal and craving
CIt cures the liver damage caused by opioids
DIt causes vomiting if other opioids are used
4.Sedang
How can the absorption of oral iron be improved?
ATake it with a cup of strong tea
BTake it with a glass of milk
CTake it at the same time as an antacid to protect the stomach
DTake it with vitamin C, such as orange juice, on an empty stomach
5.Sedang
Which patient should usually not receive a live vaccine?
AA patient receiving chemotherapy for leukaemia
BA healthy 1-year-old child
CA patient with mild seasonal allergies
DA healthy adult nurse who works on a children's ward
6.Sedang
A parent will give a liquid medicine to a child at home. Which advice is safest?
AUse the oral syringe or measuring cup supplied with it
BMix the dose into a full bottle of milk
CEstimate the dose by pouring the liquid into a small cup
DUse any kitchen teaspoon
7.Sulit
A patient taking azathioprine is prescribed allopurinol for gout. What is the main danger?
ASevere hypertension from the combination
BGout becomes worse because allopurinol is inactivated by azathioprine
CLiver enzyme induction, making azathioprine ineffective
DSevere bone marrow suppression, because azathioprine breakdown is reduced
8.Sulit
A woman with chronic hypertension who takes lisinopril is now pregnant. What is the key concern?
AAll antihypertensives must be stopped in pregnancy
BLisinopril has no known fetal effects and should be continued
CACE inhibitors harm fetal kidneys, so a safer drug is used
DLisinopril works better in pregnancy, so the dose should be increased
Kunci jawaban
1. A · A drug that is inactive until the body converts it into its active form
2. C · The use of many medicines at the same time, often five or more
3. B · It is a long-acting opioid that prevents withdrawal and craving
4. D · Take it with vitamin C, such as orange juice, on an empty stomach
5. A · A patient receiving chemotherapy for leukaemia
6. A · Use the oral syringe or measuring cup supplied with it
7. D · Severe bone marrow suppression, because azathioprine breakdown is reduced
8. C · ACE inhibitors harm fetal kidneys, so a safer drug is used
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