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Nama: ____________________ Tanggal: ____________
1.Mudah
Organ mana yang mengekskresikan sebagian besar obat larut air dan metabolitnya?
AParu-paru
BHati
CGinjal
DKulit
2.Mudah
Mengapa insulin diberikan melalui suntikan, bukan dalam bentuk tablet?
AInsulin adalah protein yang akan tercerna di saluran cerna
BInsulin terlalu toksik bagi lapisan lambung
CTablet akan melepaskannya terlalu lambat
DInsulin hanya bekerja jika langsung mencapai otot rangka
3.Mudah
Rute pemberian mana yang menghindari metabolisme lintas pertama di hati?
AIntravena
BTablet oral
CLarutan oral
DSupositoria yang diletakkan tinggi di rektum
4.Sedang
A patient is starting lamotrigine. Which adverse effect should the patient report at once?
AMild headache on the first day
BSlight tiredness in the afternoon
CAny new skin rash
DA brief change in taste
5.Sedang
After instilling eye drops, why should the patient press gently on the inner corner of the eye for a minute or two?
ATo spread the drop evenly over the eyelid
BTo make the pupil dilate faster
CTo reduce drainage into the nose and absorption into blood
DTo stop the eye from producing tears for about an hour
6.Sedang
Which teaching about antiepileptic drugs is most important?
AAlcohol has no effect on seizure control
BDo not stop the drug suddenly, as this can trigger severe seizures
CStop the drug when you have had no seizures for one whole week
DTake a double dose if you feel a seizure coming
7.Sulit
A patient on disulfiram becomes flushed, nauseated and has palpitations after using a mouthwash. What is the most likely cause?
ADisulfiram toxicity from taking too many tablets by mistake
BAn allergy to mint flavouring in the mouthwash
CAlcohol in the mouthwash caused a disulfiram–alcohol reaction
DLow blood glucose from skipping breakfast
8.Sulit
Seorang pasien yang baru mulai mengonsumsi haloperidol mengalami demam tinggi, kekakuan otot "lead-pipe", kebingungan, dan kreatin kinase yang sangat tinggi. Apa diagnosis yang paling mungkin?
ADistonia akut
BHipertermia maligna akibat anestesi
CSindrom neuroleptik maligna
DSindrom serotonin
Kunci jawaban
1. C · Ginjal
2. A · Insulin adalah protein yang akan tercerna di saluran cerna
3. A · Intravena
4. C · Any new skin rash
5. C · To reduce drainage into the nose and absorption into blood
6. B · Do not stop the drug suddenly, as this can trigger severe seizures
7. C · Alcohol in the mouthwash caused a disulfiram–alcohol reaction
8. C · Sindrom neuroleptik maligna
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