Lembar kerja Farmakologi dengan jawaban

Obat yang namanya berakhiran "-olol", seperti atenolol, termasuk golongan apa?

1. APenyekat kanal kalsium
2. BPenyekat beta
3. CPenghambat ACE
4. DStatin

How does allopurinol prevent gout?

1. AIt dissolves crystals already in the joint within hours
2. BIt inhibits xanthine oxidase, so less uric acid is made
3. CIt increases the kidney excretion of calcium
4. DIt blocks prostaglandins in the inflamed joint

How does activated charcoal work in poisoning?

1. AIt neutralises acids in the blood
2. BIt speeds up liver metabolism of the poison
3. CIt makes the patient vomit the poison before it is absorbed
4. DIt binds (adsorbs) the poison in the gut so less is absorbed

A patient given haloperidol develops a sudden painful twisting of the neck and the eyes roll upward. Which drug is usually given?

1. ADantrolene by mouth to relax the twisted neck muscles
2. BNaloxone
3. CA second dose of haloperidol
4. DAn anticholinergic such as benzatropine (benztropine)

Which adverse effects are typical of donepezil?

1. AHair loss and skin pigmentation
2. BNausea, diarrhoea and a slow heart rate
3. CWeight gain and high blood glucose
4. DDry mouth, constipation and a fast heart rate

Which teaching about antiepileptic drugs is most important?

1. ADo not stop the drug suddenly, as this can trigger severe seizures
2. BAlcohol has no effect on seizure control
3. CTake a double dose if you feel a seizure coming
4. DStop the drug when you have had no seizures for one whole week

A man on long-term testosterone therapy has a rising haematocrit. Why is this important?

1. AIt means the testosterone dose is too low
2. BA high haematocrit shows that the testosterone is not being absorbed
3. CTestosterone raises red cell production, increasing clot risk
4. DIt is a sign of liver failure caused by testosterone

Why is the TPMT enzyme often tested before azathioprine is started?

1. AHigh TPMT activity causes an allergic reaction to azathioprine
2. BTPMT is needed to absorb azathioprine from the gut
3. CTPMT testing shows whether the patient has tuberculosis
4. DLow TPMT activity causes toxic levels and marrow suppression