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Nama: ____________________ Tanggal: ____________
1.Mudah
Naltrexone helps in alcohol use disorder because it:
ABlocks opioid receptors, reducing reward and craving
BSpeeds up the liver breakdown of alcohol
CReplaces alcohol as a sedative
DCauses vomiting and flushing whenever alcohol is drunk
2.Mudah
Apa peran utama kortikosteroid inhalasi pada asma?
AMembunuh bakteri di saluran napas
BMengencerkan lendir agar dapat dibatukkan
CMeredakan bronkospasme mendadak dalam beberapa menit
DMengurangi peradangan saluran napas dan mencegah serangan
3.Mudah
Ciclosporin and tacrolimus are used mainly to:
ATreat bacterial infections after surgery
BPrevent rejection of transplanted organs
CRelieve acute pain after surgery
DLower high blood cholesterol
4.Sedang
A patient is starting olanzapine. Which monitoring is most important over the following months?
AWeight, blood glucose and blood lipids
BHearing tests and vision tests every month
CPeak expiratory flow
DINR and platelet count
5.Sedang
A patient takes low-dose weekly methotrexate for rheumatoid arthritis. Which monitoring is needed?
AWeekly INR checks and a monthly ECG to check the heart rhythm
BMonthly hearing tests
CDaily blood glucose checks
DRegular blood count, liver and kidney function tests
6.Sedang
Which early signs suggest systemic toxicity from a local anaesthetic?
APinpoint pupils and slow, shallow breathing
BNumbness around the mouth, metallic taste and tinnitus
CItchy rash and swelling only at the injection site
DHeavy sweating, salivation and diarrhoea
7.Sulit
Why is vancomycin given by mouth, not intravenously, for Clostridioides difficile infection?
AThe oral form is cheaper but has the same effect as IV
BOral vancomycin is absorbed into the blood better than IV vancomycin
CIntravenous vancomycin causes C. difficile infection
DOral vancomycin is not absorbed, so it reaches high levels in the colon
8.Sulit
A patient receiving frequent salbutamol (albuterol) nebulisers develops a fine tremor and a heart rate of 120 per minute. What is the best explanation?
AThe patient is allergic to salbutamol and needs adrenaline
BAt high doses it also stimulates beta receptors in skeletal muscle and the heart
CSalbutamol blocks muscarinic receptors in the heart
DSalbutamol causes high potassium, which speeds the heart and causes muscle twitching
Kunci jawaban
1. A · Blocks opioid receptors, reducing reward and craving
2. D · Mengurangi peradangan saluran napas dan mencegah serangan
3. B · Prevent rejection of transplanted organs
4. A · Weight, blood glucose and blood lipids
5. D · Regular blood count, liver and kidney function tests
6. B · Numbness around the mouth, metallic taste and tinnitus
7. D · Oral vancomycin is not absorbed, so it reaches high levels in the colon
8. B · At high doses it also stimulates beta receptors in skeletal muscle and the heart
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